Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
Texto Completo: | https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2014v16n5p588 |
Resumo: | The prevalence of obesity and diabetes mellitus has increased significantly in recent years and the knowledge that adipose tissue has endocrine activity and plays important roles in regulating inflammation and energy metabolism by molecular mechanisms among others is a source of new studies. This study is aimed at assessing the molecular mechanisms involved in obesity and diabetes mainly in peripheral tissues as well as the relationship of exercise in this context in the form of a literature review. The methodology used was a bibliographic survey in the main databases SciELO and PubMed of articles published between 1998 and 2012. Studies have demonstrated an interrelation between molecular mechanisms involved in the development of obesity and diabetes in central and peripheral tissues. Several studies have shown that physical exercise greatly contributes to the reduction of prevalence, control and even in the treatment of obesity and diabetes. However, there is need for further studies relating various types of exercise at different intensities and volumes and preferably with humans, as well as the study model, that when using animals, exercise programs should be developed concurrently with fat-rich diets in order to assess physical exercise and its role in the prevention of these diseases. |
id |
UFSC-16_c1697593f14970a4c863d2626459bd35 |
---|---|
oai_identifier_str |
oai:periodicos.ufsc.br:article/30299 |
network_acronym_str |
UFSC-16 |
network_name_str |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
repository_id_str |
|
spelling |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signalingEfeitos do exercicio físico em parâmetros moleculares da via de sinalização da insulina e obesidadeThe prevalence of obesity and diabetes mellitus has increased significantly in recent years and the knowledge that adipose tissue has endocrine activity and plays important roles in regulating inflammation and energy metabolism by molecular mechanisms among others is a source of new studies. This study is aimed at assessing the molecular mechanisms involved in obesity and diabetes mainly in peripheral tissues as well as the relationship of exercise in this context in the form of a literature review. The methodology used was a bibliographic survey in the main databases SciELO and PubMed of articles published between 1998 and 2012. Studies have demonstrated an interrelation between molecular mechanisms involved in the development of obesity and diabetes in central and peripheral tissues. Several studies have shown that physical exercise greatly contributes to the reduction of prevalence, control and even in the treatment of obesity and diabetes. However, there is need for further studies relating various types of exercise at different intensities and volumes and preferably with humans, as well as the study model, that when using animals, exercise programs should be developed concurrently with fat-rich diets in order to assess physical exercise and its role in the prevention of these diseases.A prevalência da obesidade e diabetes mellitus tem aumentado significativamente nos últimos anos e o conhecimento de que o tecido adiposo tem atividade endócrina e desempenha funções importantes na regulação da inflamação e no metabolismo energético por meio de mecanismos moleculares entre outros é fonte de novas pesquisas. Este trabalho versa sobre os mecanismos moleculares envolvidos na obesidade e diabetes principalmente em tecidos periféricos bem como a relação do exercício físico neste contexto, em forma de revisão bibliográfica. A metodologia foi levantamento bibliográfico nas principais bases de dados: Scielo e PubMed, publicados no período de 1998 a 2012. Os estudos tem demonstrado uma inter-relação entre os mecanismos moleculares envolvidos no desenvolvimento da obesidade e diabetes em tecidos periféricos e centrais. Do ponto de vista do exercício físico, vários estudos demonstram uma contribuição muito grande na diminuição da prevalência, no controle e até mesmo no tratamento da obesidade e diabetes. No entanto há necessidade de estudos mais aprofundados relacionando diversos tipos de exercício físico, em volumes e intensidades diferentes e preferencialmente com humanos, bem como o modelo de estudo, que quando utilizado animais, os programas de exercício devem ser desenvolvidos concomitantemente com alimentação rica em gordura, verificando mais intensamente o exercício físico e o seu real papel na prevenção destas doenças. Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil2014-08-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion"Avaliado por Pares","Artigo Solicitado""Avaliado por Pares", "Artigo Solicitado"revisão de literaturainfo:eu-repo/semantics/otherapplication/pdfhttps://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2014v16n5p58810.1590/1980-0037.2014v16n5p588Brazilian Journal of Kinanthropometry and Human Performance; Vol. 16 No. 5 (2014); 588-595Revista Brasileira de Cineantropometria e Desempenho Humano; v. 16 n. 5 (2014); 588-5951980-00371415-8426reponame:Revista Brasileira de Cineantropometria & Desempenho Humano (Online)instname:Universidade Federal de Santa Catarina (UFSC)instacron:UFSCenghttps://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2014v16n5p588/27560Farias, Joni Marcio deinfo:eu-repo/semantics/openAccess2018-12-05T08:26:44Zoai:periodicos.ufsc.br:article/30299Revistahttps://periodicos.ufsc.br/index.php/rbcdh/PUBhttps://periodicos.ufsc.br/index.php/rbcdh/oairbcdh@contato.ufsc.br || portaldeperiodicos.bu@contato.ufsc.br1980-00371415-8426opendoar:2018-12-05T08:26:44Revista Brasileira de Cineantropometria & Desempenho Humano (Online) - Universidade Federal de Santa Catarina (UFSC)false |
dc.title.none.fl_str_mv |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling Efeitos do exercicio físico em parâmetros moleculares da via de sinalização da insulina e obesidade |
title |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling |
spellingShingle |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling Farias, Joni Marcio de |
title_short |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling |
title_full |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling |
title_fullStr |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling |
title_full_unstemmed |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling |
title_sort |
Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling |
author |
Farias, Joni Marcio de |
author_facet |
Farias, Joni Marcio de |
author_role |
author |
dc.contributor.author.fl_str_mv |
Farias, Joni Marcio de |
description |
The prevalence of obesity and diabetes mellitus has increased significantly in recent years and the knowledge that adipose tissue has endocrine activity and plays important roles in regulating inflammation and energy metabolism by molecular mechanisms among others is a source of new studies. This study is aimed at assessing the molecular mechanisms involved in obesity and diabetes mainly in peripheral tissues as well as the relationship of exercise in this context in the form of a literature review. The methodology used was a bibliographic survey in the main databases SciELO and PubMed of articles published between 1998 and 2012. Studies have demonstrated an interrelation between molecular mechanisms involved in the development of obesity and diabetes in central and peripheral tissues. Several studies have shown that physical exercise greatly contributes to the reduction of prevalence, control and even in the treatment of obesity and diabetes. However, there is need for further studies relating various types of exercise at different intensities and volumes and preferably with humans, as well as the study model, that when using animals, exercise programs should be developed concurrently with fat-rich diets in order to assess physical exercise and its role in the prevention of these diseases. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-08-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion "Avaliado por Pares","Artigo Solicitado" "Avaliado por Pares", "Artigo Solicitado" revisão de literatura info:eu-repo/semantics/other |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2014v16n5p588 10.1590/1980-0037.2014v16n5p588 |
url |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2014v16n5p588 |
identifier_str_mv |
10.1590/1980-0037.2014v16n5p588 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2014v16n5p588/27560 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil |
publisher.none.fl_str_mv |
Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil |
dc.source.none.fl_str_mv |
Brazilian Journal of Kinanthropometry and Human Performance; Vol. 16 No. 5 (2014); 588-595 Revista Brasileira de Cineantropometria e Desempenho Humano; v. 16 n. 5 (2014); 588-595 1980-0037 1415-8426 reponame:Revista Brasileira de Cineantropometria & Desempenho Humano (Online) instname:Universidade Federal de Santa Catarina (UFSC) instacron:UFSC |
instname_str |
Universidade Federal de Santa Catarina (UFSC) |
instacron_str |
UFSC |
institution |
UFSC |
reponame_str |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
collection |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) - Universidade Federal de Santa Catarina (UFSC) |
repository.mail.fl_str_mv |
rbcdh@contato.ufsc.br || portaldeperiodicos.bu@contato.ufsc.br |
_version_ |
1789435123534397440 |