Epidemiological and therapeutic profile of patients with cryptococosis in the school hospital of Santa Maria/RS

• Autor(a) principal: Ianiski, Lara B
• Data de Publicação: 2018
• Outros Autores: Azevedo, Maria Isabel, Weiblen, Carla, Stibbe, Paula Cristina, Tondolo, Juliana S M, Botton, Sônia de Avila
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Saúde (Santa Maria)
• Texto Completo: https://periodicos.ufsm.br/revistasaude/article/view/32507
• topic: Cryptococcus spp.; Fungal diseases; Diagnosis; Epidemiology; Cryptococcus spp.; Doenças fúngicas; Diagnóstico; Epidemiologia

Cryptococcosis is a fungal disease caused by yeasts of the complex Cryptococcus neoformans and Cryptococcus gattii. The infection usually occurs by inhaling the basidiospores of the fungus present in the environment. Severe cases occur due to infection of the central nervous system. The disease has a worldwide distribution, mainly associated to the immunocompromised individuals with human immunodeficiency virus (HIV). This study aimed to verify the epidemiological profile and therapeutic protocols of patients diagnosed with cryptococcosis at the Hospital Universitário de Santa Maria (Santa Maria, RS), from March 2010 to March 2017. A total of 46 clinical records were evaluated, the profile of the patients was predominantly Caucasian, aged between 31 and 50 years, with HIV, presenting a CD4 + cell count <100 cells / μL and with a prevalent clinical form neurocryptococcosis. The combination of amphotericin B and fluconazole was the therapeutic protocol adopted in the majority of patients studied.