Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional Manancial UFSM |
Texto Completo: | http://repositorio.ufsm.br/handle/1/10146 |
Resumo: | The skin is the protection, thermoregulation, and control of water loss from the body. When there is continuity injury in this tissue, any kind of trauma can alter its functions. The healing process depends on factors such as location and size of the lesion, age and systemic conditions of the patient and the surgical technique used to repair it. Attempts to intervene in healing dates back to antiquity, when it was already recognized the importance of protecting the wounds to avoid complications in the process. Some resources are used as adjuvants in the healing process in order to obtain better results. For this experiment, we used 20 New Zealand White rabbits (Oryctolagus cuniculus). The animals were randomly divided into four groups of five animals each, in which we performed a skin wound 4cm ². In group A, animals received no treatment, group B was treated with transplantation of autologous mesenchymal stem cells, group C was treated with local application of therapeutic ultrasound, and group D laser was applied on site. The wounds were assessed at 7, 14 and 21 days postoperatively by measuring the area and biopsy. At the end of the study it was observed a statistical difference the group treated with cells in the healing process between groups. |
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2013-09-252013-09-252012-10-08ROSA, Maurício Borges da. UNDIFFERENTIATED ALLOGENEIC MESENCHYMAL STROMAL CELLS, ULTRASOUND THERAPEUTIC OR LASER IN WOUND CARE SKIN OF RABBITS. 2012. 60 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2012.http://repositorio.ufsm.br/handle/1/10146The skin is the protection, thermoregulation, and control of water loss from the body. When there is continuity injury in this tissue, any kind of trauma can alter its functions. The healing process depends on factors such as location and size of the lesion, age and systemic conditions of the patient and the surgical technique used to repair it. Attempts to intervene in healing dates back to antiquity, when it was already recognized the importance of protecting the wounds to avoid complications in the process. Some resources are used as adjuvants in the healing process in order to obtain better results. For this experiment, we used 20 New Zealand White rabbits (Oryctolagus cuniculus). The animals were randomly divided into four groups of five animals each, in which we performed a skin wound 4cm ². In group A, animals received no treatment, group B was treated with transplantation of autologous mesenchymal stem cells, group C was treated with local application of therapeutic ultrasound, and group D laser was applied on site. The wounds were assessed at 7, 14 and 21 days postoperatively by measuring the area and biopsy. At the end of the study it was observed a statistical difference the group treated with cells in the healing process between groups.A pele faz a proteção, termorregulação e controle da perda de água do corpo. Quando há lesão de continuidade neste tecido qualquer que seja o tipo de trauma pode alterar suas funções. O processo de cicatrização depende de alguns fatores como: local e tamanho da lesão, idade e condições sistêmicas do paciente bem como da técnica cirúrgica empregada para sua correção. As tentativas de intervir na cicatrização remontam à antiguidade, quando já se reconhecia a importância de proteger as feridas para evitar complicações neste processo. Alguns recursos são usados como adjuvantes no processo cicatricial a fim de se obter melhor resultado. Os objetivos foram avaliar a cicatrização das feridas temporal e histologicamente. Para a realização deste experimento, foram utilizados 20 coelhos (Oryctolagus cuniculus) da raça Nova Zelândia Branco. Os animais foram distribuídos aleatoriamente em quatro grupos de cinco animais cada, nos quais foi realizada uma ferida cutânea de 4cm² de área. No grupo A os animais não receberam nenhum tipo de tratamento, o grupo B foi tratado com transplante autógeno de células-tronco mesenquimais, o grupo C foi tratado com aplicação local de ultrassom terapêutico; e o grupo D foi aplicado laser no local. As feridas foram avaliadas aos 7, 14 e 21 dias de pós-operatório pela medida da área e biópsia. Ao final do estudo foi possível observar diferença estatística do grupo tratado com células no processo de cicatrização entre os grupos.Conselho Nacional de Desenvolvimento Científico e Tecnológicoapplication/pdfporUniversidade Federal de Santa MariaPrograma de Pós-Graduação em Medicina VeterináriaUFSMBRMedicina VeterináriaCélulas troncoCicatrizaçãoPelePlanimetriaReparoStem cellsWound healingSkinPlanimetryRepairCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIACélulas estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhosUndifferentiated allogeneic mesenchymal stromal cells, ultrasound therapeutic or laser in wound care skin of rabbitsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisPippi, Ney Luishttp://lattes.cnpq.br/7254479300721225Krause, Alexandrehttp://lattes.cnpq.br/7760558908777387Pedrozo, Josaine Cristina da Silva Rappetihttp://lattes.cnpq.br/0920500176191229http://lattes.cnpq.br/1551300597379142Rosa, Maurício Borges da500500000007400500300500500e7d62db5-d9ba-4842-bf91-8dd7b40e28b1e3813214-dd29-4bf9-af92-34272cde9d7448b1731f-9fa9-4553-ab4a-18302b9fc5149fc1aa2b-e7bc-4d2b-9f3d-ffdc640f3173info:eu-repo/semantics/openAccessreponame:Repositório Institucional Manancial UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMORIGINALROSA, MAURICIO BORGES.pdfapplication/pdf1113266http://repositorio.ufsm.br/bitstream/1/10146/1/ROSA%2c%20MAURICIO%20BORGES.pdf67a2d2fd2c9e8150a7a0cf478279f5e5MD51TEXTROSA, MAURICIO BORGES.pdf.txtROSA, MAURICIO BORGES.pdf.txtExtracted texttext/plain95161http://repositorio.ufsm.br/bitstream/1/10146/2/ROSA%2c%20MAURICIO%20BORGES.pdf.txt4a3b02c66685f087a7318a1b64fbb7a2MD52THUMBNAILROSA, MAURICIO BORGES.pdf.jpgROSA, MAURICIO BORGES.pdf.jpgIM Thumbnailimage/jpeg5209http://repositorio.ufsm.br/bitstream/1/10146/3/ROSA%2c%20MAURICIO%20BORGES.pdf.jpg3251c37a0beea79080e3b45e836a84f7MD531/101462022-01-18 09:47:30.383oai:repositorio.ufsm.br:1/10146Repositório Institucionalhttp://repositorio.ufsm.br/PUBhttp://repositorio.ufsm.br/oai/requestouvidoria@ufsm.bropendoar:39132022-01-18T12:47:30Repositório Institucional Manancial UFSM - Universidade Federal de Santa Maria (UFSM)false |
dc.title.por.fl_str_mv |
Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos |
dc.title.alternative.eng.fl_str_mv |
Undifferentiated allogeneic mesenchymal stromal cells, ultrasound therapeutic or laser in wound care skin of rabbits |
title |
Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos |
spellingShingle |
Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos Rosa, Maurício Borges da Células tronco Cicatrização Pele Planimetria Reparo Stem cells Wound healing Skin Planimetry Repair CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos |
title_full |
Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos |
title_fullStr |
Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos |
title_full_unstemmed |
Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos |
title_sort |
Células estromais mesenquimais indiferenciadas alogênicas, ultrassom terapêutico ou laser no tratamento de feridas cutâneas de coelhos |
author |
Rosa, Maurício Borges da |
author_facet |
Rosa, Maurício Borges da |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Pippi, Ney Luis |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/7254479300721225 |
dc.contributor.referee1.fl_str_mv |
Krause, Alexandre |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/7760558908777387 |
dc.contributor.referee2.fl_str_mv |
Pedrozo, Josaine Cristina da Silva Rappeti |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/0920500176191229 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/1551300597379142 |
dc.contributor.author.fl_str_mv |
Rosa, Maurício Borges da |
contributor_str_mv |
Pippi, Ney Luis Krause, Alexandre Pedrozo, Josaine Cristina da Silva Rappeti |
dc.subject.por.fl_str_mv |
Células tronco Cicatrização Pele Planimetria Reparo |
topic |
Células tronco Cicatrização Pele Planimetria Reparo Stem cells Wound healing Skin Planimetry Repair CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
dc.subject.eng.fl_str_mv |
Stem cells Wound healing Skin Planimetry Repair |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
The skin is the protection, thermoregulation, and control of water loss from the body. When there is continuity injury in this tissue, any kind of trauma can alter its functions. The healing process depends on factors such as location and size of the lesion, age and systemic conditions of the patient and the surgical technique used to repair it. Attempts to intervene in healing dates back to antiquity, when it was already recognized the importance of protecting the wounds to avoid complications in the process. Some resources are used as adjuvants in the healing process in order to obtain better results. For this experiment, we used 20 New Zealand White rabbits (Oryctolagus cuniculus). The animals were randomly divided into four groups of five animals each, in which we performed a skin wound 4cm ². In group A, animals received no treatment, group B was treated with transplantation of autologous mesenchymal stem cells, group C was treated with local application of therapeutic ultrasound, and group D laser was applied on site. The wounds were assessed at 7, 14 and 21 days postoperatively by measuring the area and biopsy. At the end of the study it was observed a statistical difference the group treated with cells in the healing process between groups. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012-10-08 |
dc.date.accessioned.fl_str_mv |
2013-09-25 |
dc.date.available.fl_str_mv |
2013-09-25 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
ROSA, Maurício Borges da. UNDIFFERENTIATED ALLOGENEIC MESENCHYMAL STROMAL CELLS, ULTRASOUND THERAPEUTIC OR LASER IN WOUND CARE SKIN OF RABBITS. 2012. 60 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2012. |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufsm.br/handle/1/10146 |
identifier_str_mv |
ROSA, Maurício Borges da. UNDIFFERENTIATED ALLOGENEIC MESENCHYMAL STROMAL CELLS, ULTRASOUND THERAPEUTIC OR LASER IN WOUND CARE SKIN OF RABBITS. 2012. 60 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2012. |
url |
http://repositorio.ufsm.br/handle/1/10146 |
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por |
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Universidade Federal de Santa Maria |
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UFSM |
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Medicina Veterinária |
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Universidade Federal de Santa Maria |
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