Minimum alveolar concentration of isoflurane in dogs administered two morphine doses

Detalhes bibliográficos
Autor(a) principal: Coelho,Karina
Data de Publicação: 2017
Outros Autores: Monteiro,Eduardo Raposo, Bressan,Thais Feres, Monteiro,Betânia Souza, Campagnol,Daniela, Alievi,Marcelo Meller
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Ciência Rural
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001100601
Resumo: ABSTRACT: This study aimed to evaluate the effects of intramuscular 0.5mg kg-1 (MOR0.5) and 1.0mg kg-1 (MOR1.0) morphine premedication on the minimum alveolar concentration of isoflurane (ISOMAC) in dogs. Eighteen client-owned female dogs were scheduled for elective ovariohysterectomy. Dogs received intramuscular MOR0.5 or MOR1.0 as premedication and propofol IV for induction of anesthesia. Isoflurane was delivered for maintenance of anesthesia and dogs were maintained under normocapnia and normothermia. Determinations of the ISOMAC were conducted by use of the “up-and-down” method. Noxious stimulus (placement of Backhaus towel clamps, a midline skin incision and subcutaneous tissue dissection) was delivered approximately 50 minutes after premedication with MOR0.5 or MOR1.0. The calculated ISOMAC was 0.98±0.15% in MOR0.5 and 0.80±0.08% in MOR1.0. The ISOMAC was significantly lower in MOR1.0 compared with MOR0.5 (P=0.010). Results of this study suggested that intramuscular premedication with morphine 0.5 and 1.0mg kg-1 decreases the ISOMAC in a dose-related manner in dogs.
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spelling Minimum alveolar concentration of isoflurane in dogs administered two morphine dosesautonomic responsecanineinhalational anestheticsopioidsABSTRACT: This study aimed to evaluate the effects of intramuscular 0.5mg kg-1 (MOR0.5) and 1.0mg kg-1 (MOR1.0) morphine premedication on the minimum alveolar concentration of isoflurane (ISOMAC) in dogs. Eighteen client-owned female dogs were scheduled for elective ovariohysterectomy. Dogs received intramuscular MOR0.5 or MOR1.0 as premedication and propofol IV for induction of anesthesia. Isoflurane was delivered for maintenance of anesthesia and dogs were maintained under normocapnia and normothermia. Determinations of the ISOMAC were conducted by use of the “up-and-down” method. Noxious stimulus (placement of Backhaus towel clamps, a midline skin incision and subcutaneous tissue dissection) was delivered approximately 50 minutes after premedication with MOR0.5 or MOR1.0. The calculated ISOMAC was 0.98±0.15% in MOR0.5 and 0.80±0.08% in MOR1.0. The ISOMAC was significantly lower in MOR1.0 compared with MOR0.5 (P=0.010). Results of this study suggested that intramuscular premedication with morphine 0.5 and 1.0mg kg-1 decreases the ISOMAC in a dose-related manner in dogs.Universidade Federal de Santa Maria2017-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001100601Ciência Rural v.47 n.11 2017reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/0103-8478cr20170132info:eu-repo/semantics/openAccessCoelho,KarinaMonteiro,Eduardo RaposoBressan,Thais FeresMonteiro,Betânia SouzaCampagnol,DanielaAlievi,Marcelo Mellereng2017-09-18T00:00:00ZRevista
dc.title.none.fl_str_mv Minimum alveolar concentration of isoflurane in dogs administered two morphine doses
title Minimum alveolar concentration of isoflurane in dogs administered two morphine doses
spellingShingle Minimum alveolar concentration of isoflurane in dogs administered two morphine doses
Coelho,Karina
autonomic response
canine
inhalational anesthetics
opioids
title_short Minimum alveolar concentration of isoflurane in dogs administered two morphine doses
title_full Minimum alveolar concentration of isoflurane in dogs administered two morphine doses
title_fullStr Minimum alveolar concentration of isoflurane in dogs administered two morphine doses
title_full_unstemmed Minimum alveolar concentration of isoflurane in dogs administered two morphine doses
title_sort Minimum alveolar concentration of isoflurane in dogs administered two morphine doses
author Coelho,Karina
author_facet Coelho,Karina
Monteiro,Eduardo Raposo
Bressan,Thais Feres
Monteiro,Betânia Souza
Campagnol,Daniela
Alievi,Marcelo Meller
author_role author
author2 Monteiro,Eduardo Raposo
Bressan,Thais Feres
Monteiro,Betânia Souza
Campagnol,Daniela
Alievi,Marcelo Meller
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Coelho,Karina
Monteiro,Eduardo Raposo
Bressan,Thais Feres
Monteiro,Betânia Souza
Campagnol,Daniela
Alievi,Marcelo Meller
dc.subject.por.fl_str_mv autonomic response
canine
inhalational anesthetics
opioids
topic autonomic response
canine
inhalational anesthetics
opioids
description ABSTRACT: This study aimed to evaluate the effects of intramuscular 0.5mg kg-1 (MOR0.5) and 1.0mg kg-1 (MOR1.0) morphine premedication on the minimum alveolar concentration of isoflurane (ISOMAC) in dogs. Eighteen client-owned female dogs were scheduled for elective ovariohysterectomy. Dogs received intramuscular MOR0.5 or MOR1.0 as premedication and propofol IV for induction of anesthesia. Isoflurane was delivered for maintenance of anesthesia and dogs were maintained under normocapnia and normothermia. Determinations of the ISOMAC were conducted by use of the “up-and-down” method. Noxious stimulus (placement of Backhaus towel clamps, a midline skin incision and subcutaneous tissue dissection) was delivered approximately 50 minutes after premedication with MOR0.5 or MOR1.0. The calculated ISOMAC was 0.98±0.15% in MOR0.5 and 0.80±0.08% in MOR1.0. The ISOMAC was significantly lower in MOR1.0 compared with MOR0.5 (P=0.010). Results of this study suggested that intramuscular premedication with morphine 0.5 and 1.0mg kg-1 decreases the ISOMAC in a dose-related manner in dogs.
publishDate 2017
dc.date.none.fl_str_mv 2017-11-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001100601
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001100601
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0103-8478cr20170132
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv Ciência Rural v.47 n.11 2017
reponame:Ciência Rural
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Ciência Rural
collection Ciência Rural
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1749140552055521280

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