Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2

Detalhes bibliográficos
Autor(a) principal: Zlotowski,Priscila
Data de Publicação: 2009
Outros Autores: Corrêa,André Mendes Ribeiro, Barcellos,David Emílio Santos Neves de, Cardoso,Marisa Ribeiro de Itapema, Vasconcelos,Anílton Cesar, Castro,Luiza Amaral de, Driemeier,David
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Ciência Rural
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025
Resumo: Samples of intestine with necrotic enteritis from 63 pigs naturally infected with porcine circovirus type 2 (PCV2) were studied. Colon was the main target of PCV2 associated necrotic enteritis in 60 cases. Immunohistological investigations were carried out to detect the presence of PCV2 in necrotic lesions and to identify the type of cells infected by the virus. Crypt epithelial cells had positive labelling for PCV2 in 17 cases. Depletion of goblet cells occurred in 10 cases. In 24 necrotic enteritis cases, co-infection of PCV2 and Salmonella was identified. An increased rate of apoptosis in the crypt epithelial cells of the large intestine from PCV2 of naturally infected pigs was observed. Immunohistochemical findings confirmed the presence of PCV2 within cells from necrotic intestinal tissue, suggesting that PCV2 may play a role in the development of those lesions. Diagnosis of necrotic enteritis associated with PCV2 should be based on the detection of PCV2 antigen or DNA in the necrotizing lesions. However, bacteriological examination should be performed to rule out the presence of bacterial agents, since co-infections are likely to occur in PCV2 affected pigs.
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spelling Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2necrotic enterocolitisPCV2 infectionswineSamples of intestine with necrotic enteritis from 63 pigs naturally infected with porcine circovirus type 2 (PCV2) were studied. Colon was the main target of PCV2 associated necrotic enteritis in 60 cases. Immunohistological investigations were carried out to detect the presence of PCV2 in necrotic lesions and to identify the type of cells infected by the virus. Crypt epithelial cells had positive labelling for PCV2 in 17 cases. Depletion of goblet cells occurred in 10 cases. In 24 necrotic enteritis cases, co-infection of PCV2 and Salmonella was identified. An increased rate of apoptosis in the crypt epithelial cells of the large intestine from PCV2 of naturally infected pigs was observed. Immunohistochemical findings confirmed the presence of PCV2 within cells from necrotic intestinal tissue, suggesting that PCV2 may play a role in the development of those lesions. Diagnosis of necrotic enteritis associated with PCV2 should be based on the detection of PCV2 antigen or DNA in the necrotizing lesions. However, bacteriological examination should be performed to rule out the presence of bacterial agents, since co-infections are likely to occur in PCV2 affected pigs.Universidade Federal de Santa Maria2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025Ciência Rural v.39 n.6 2009reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/S0103-84782009005000115info:eu-repo/semantics/openAccessZlotowski,PriscilaCorrêa,André Mendes RibeiroBarcellos,David Emílio Santos Neves deCardoso,Marisa Ribeiro de ItapemaVasconcelos,Anílton CesarCastro,Luiza Amaral deDriemeier,Davideng2009-09-10T00:00:00ZRevista
dc.title.none.fl_str_mv Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
title Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
spellingShingle Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
Zlotowski,Priscila
necrotic enterocolitis
PCV2 infection
swine
title_short Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
title_full Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
title_fullStr Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
title_full_unstemmed Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
title_sort Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
author Zlotowski,Priscila
author_facet Zlotowski,Priscila
Corrêa,André Mendes Ribeiro
Barcellos,David Emílio Santos Neves de
Cardoso,Marisa Ribeiro de Itapema
Vasconcelos,Anílton Cesar
Castro,Luiza Amaral de
Driemeier,David
author_role author
author2 Corrêa,André Mendes Ribeiro
Barcellos,David Emílio Santos Neves de
Cardoso,Marisa Ribeiro de Itapema
Vasconcelos,Anílton Cesar
Castro,Luiza Amaral de
Driemeier,David
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Zlotowski,Priscila
Corrêa,André Mendes Ribeiro
Barcellos,David Emílio Santos Neves de
Cardoso,Marisa Ribeiro de Itapema
Vasconcelos,Anílton Cesar
Castro,Luiza Amaral de
Driemeier,David
dc.subject.por.fl_str_mv necrotic enterocolitis
PCV2 infection
swine
topic necrotic enterocolitis
PCV2 infection
swine
description Samples of intestine with necrotic enteritis from 63 pigs naturally infected with porcine circovirus type 2 (PCV2) were studied. Colon was the main target of PCV2 associated necrotic enteritis in 60 cases. Immunohistological investigations were carried out to detect the presence of PCV2 in necrotic lesions and to identify the type of cells infected by the virus. Crypt epithelial cells had positive labelling for PCV2 in 17 cases. Depletion of goblet cells occurred in 10 cases. In 24 necrotic enteritis cases, co-infection of PCV2 and Salmonella was identified. An increased rate of apoptosis in the crypt epithelial cells of the large intestine from PCV2 of naturally infected pigs was observed. Immunohistochemical findings confirmed the presence of PCV2 within cells from necrotic intestinal tissue, suggesting that PCV2 may play a role in the development of those lesions. Diagnosis of necrotic enteritis associated with PCV2 should be based on the detection of PCV2 antigen or DNA in the necrotizing lesions. However, bacteriological examination should be performed to rule out the presence of bacterial agents, since co-infections are likely to occur in PCV2 affected pigs.
publishDate 2009
dc.date.none.fl_str_mv 2009-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-84782009005000115
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv Ciência Rural v.39 n.6 2009
reponame:Ciência Rural
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Ciência Rural
collection Ciência Rural
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repository.mail.fl_str_mv
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