Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Ciência Rural |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025 |
Resumo: | Samples of intestine with necrotic enteritis from 63 pigs naturally infected with porcine circovirus type 2 (PCV2) were studied. Colon was the main target of PCV2 associated necrotic enteritis in 60 cases. Immunohistological investigations were carried out to detect the presence of PCV2 in necrotic lesions and to identify the type of cells infected by the virus. Crypt epithelial cells had positive labelling for PCV2 in 17 cases. Depletion of goblet cells occurred in 10 cases. In 24 necrotic enteritis cases, co-infection of PCV2 and Salmonella was identified. An increased rate of apoptosis in the crypt epithelial cells of the large intestine from PCV2 of naturally infected pigs was observed. Immunohistochemical findings confirmed the presence of PCV2 within cells from necrotic intestinal tissue, suggesting that PCV2 may play a role in the development of those lesions. Diagnosis of necrotic enteritis associated with PCV2 should be based on the detection of PCV2 antigen or DNA in the necrotizing lesions. However, bacteriological examination should be performed to rule out the presence of bacterial agents, since co-infections are likely to occur in PCV2 affected pigs. |
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Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2necrotic enterocolitisPCV2 infectionswineSamples of intestine with necrotic enteritis from 63 pigs naturally infected with porcine circovirus type 2 (PCV2) were studied. Colon was the main target of PCV2 associated necrotic enteritis in 60 cases. Immunohistological investigations were carried out to detect the presence of PCV2 in necrotic lesions and to identify the type of cells infected by the virus. Crypt epithelial cells had positive labelling for PCV2 in 17 cases. Depletion of goblet cells occurred in 10 cases. In 24 necrotic enteritis cases, co-infection of PCV2 and Salmonella was identified. An increased rate of apoptosis in the crypt epithelial cells of the large intestine from PCV2 of naturally infected pigs was observed. Immunohistochemical findings confirmed the presence of PCV2 within cells from necrotic intestinal tissue, suggesting that PCV2 may play a role in the development of those lesions. Diagnosis of necrotic enteritis associated with PCV2 should be based on the detection of PCV2 antigen or DNA in the necrotizing lesions. However, bacteriological examination should be performed to rule out the presence of bacterial agents, since co-infections are likely to occur in PCV2 affected pigs.Universidade Federal de Santa Maria2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025Ciência Rural v.39 n.6 2009reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/S0103-84782009005000115info:eu-repo/semantics/openAccessZlotowski,PriscilaCorrêa,André Mendes RibeiroBarcellos,David Emílio Santos Neves deCardoso,Marisa Ribeiro de ItapemaVasconcelos,Anílton CesarCastro,Luiza Amaral deDriemeier,Davideng2009-09-10T00:00:00ZRevista |
dc.title.none.fl_str_mv |
Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2 |
title |
Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2 |
spellingShingle |
Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2 Zlotowski,Priscila necrotic enterocolitis PCV2 infection swine |
title_short |
Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2 |
title_full |
Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2 |
title_fullStr |
Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2 |
title_full_unstemmed |
Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2 |
title_sort |
Necrotic enterocolitis in pigs naturally infected by porcine circovirus type 2 |
author |
Zlotowski,Priscila |
author_facet |
Zlotowski,Priscila Corrêa,André Mendes Ribeiro Barcellos,David Emílio Santos Neves de Cardoso,Marisa Ribeiro de Itapema Vasconcelos,Anílton Cesar Castro,Luiza Amaral de Driemeier,David |
author_role |
author |
author2 |
Corrêa,André Mendes Ribeiro Barcellos,David Emílio Santos Neves de Cardoso,Marisa Ribeiro de Itapema Vasconcelos,Anílton Cesar Castro,Luiza Amaral de Driemeier,David |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Zlotowski,Priscila Corrêa,André Mendes Ribeiro Barcellos,David Emílio Santos Neves de Cardoso,Marisa Ribeiro de Itapema Vasconcelos,Anílton Cesar Castro,Luiza Amaral de Driemeier,David |
dc.subject.por.fl_str_mv |
necrotic enterocolitis PCV2 infection swine |
topic |
necrotic enterocolitis PCV2 infection swine |
description |
Samples of intestine with necrotic enteritis from 63 pigs naturally infected with porcine circovirus type 2 (PCV2) were studied. Colon was the main target of PCV2 associated necrotic enteritis in 60 cases. Immunohistological investigations were carried out to detect the presence of PCV2 in necrotic lesions and to identify the type of cells infected by the virus. Crypt epithelial cells had positive labelling for PCV2 in 17 cases. Depletion of goblet cells occurred in 10 cases. In 24 necrotic enteritis cases, co-infection of PCV2 and Salmonella was identified. An increased rate of apoptosis in the crypt epithelial cells of the large intestine from PCV2 of naturally infected pigs was observed. Immunohistochemical findings confirmed the presence of PCV2 within cells from necrotic intestinal tissue, suggesting that PCV2 may play a role in the development of those lesions. Diagnosis of necrotic enteritis associated with PCV2 should be based on the detection of PCV2 antigen or DNA in the necrotizing lesions. However, bacteriological examination should be performed to rule out the presence of bacterial agents, since co-infections are likely to occur in PCV2 affected pigs. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000600025 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-84782009005000115 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
dc.source.none.fl_str_mv |
Ciência Rural v.39 n.6 2009 reponame:Ciência Rural instname:Universidade Federal de Santa Maria (UFSM) instacron:UFSM |
instname_str |
Universidade Federal de Santa Maria (UFSM) |
instacron_str |
UFSM |
institution |
UFSM |
reponame_str |
Ciência Rural |
collection |
Ciência Rural |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1749140534332489728 |