Bovine abortion by a vaccine strain of Bacillus anthracis
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Ciência Rural |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020001200554 |
Resumo: | ABSTRACT: This paper reports the abortion of a male Aberdeen Angus bovine by a vaccine strain of Bacillus anthracis, describing the pathological and microbiological findings and the genome sequence. Necropsy findings included multifocal areas of hemorrhage in different organs. Histologically, various organs showed hemorrhage, fibrin exudation, necrosis associated with countless bacillary bacterial clumps and severe neutrophilic inflammatory infiltrate. In the microbiological examination, numerous rough, nonhemolytic, gray and dry colonies with irregular edges were isolated from liver, lung and abomasum content samples. Gram staining revealed square-ended Gram-positive rods arranged in chains. B. anthracis identification was confirmed by detection of the molecular chromosomal marker Ba813. The genomes from the isolated B. anthracis (named SPV842_15) and from the isolated vaccinal strain (Brazilian vaccinal strain), which was recovered from a commercial vaccine used in the pregnant cow, were sequenced. Genomic comparisons displayed a high level of nucleotide identity in the comparisons between B. anthracis SPV842_15 and the B. anthracis Brazilian vaccinal strain (98,2%). Furthermore, in both strains, only the plasmid pX01 sequence was detected. Although, vaccination against anthrax is characterized by an elevated protective profile and very low residual virulence, immunization with Sterne strains can cause abortion in cattle, presumably by the plasmid pX01 toxins in rare or special situations. |
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Bovine abortion by a vaccine strain of Bacillus anthracisanthraxcattlefetal lossinfectious diseasesABSTRACT: This paper reports the abortion of a male Aberdeen Angus bovine by a vaccine strain of Bacillus anthracis, describing the pathological and microbiological findings and the genome sequence. Necropsy findings included multifocal areas of hemorrhage in different organs. Histologically, various organs showed hemorrhage, fibrin exudation, necrosis associated with countless bacillary bacterial clumps and severe neutrophilic inflammatory infiltrate. In the microbiological examination, numerous rough, nonhemolytic, gray and dry colonies with irregular edges were isolated from liver, lung and abomasum content samples. Gram staining revealed square-ended Gram-positive rods arranged in chains. B. anthracis identification was confirmed by detection of the molecular chromosomal marker Ba813. The genomes from the isolated B. anthracis (named SPV842_15) and from the isolated vaccinal strain (Brazilian vaccinal strain), which was recovered from a commercial vaccine used in the pregnant cow, were sequenced. Genomic comparisons displayed a high level of nucleotide identity in the comparisons between B. anthracis SPV842_15 and the B. anthracis Brazilian vaccinal strain (98,2%). Furthermore, in both strains, only the plasmid pX01 sequence was detected. Although, vaccination against anthrax is characterized by an elevated protective profile and very low residual virulence, immunization with Sterne strains can cause abortion in cattle, presumably by the plasmid pX01 toxins in rare or special situations.Universidade Federal de Santa Maria2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020001200554Ciência Rural v.50 n.12 2020reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/0103-8478cr20200264info:eu-repo/semantics/openAccessBassuino,Daniele MariathSiqueira,Franciele MaboniKonradt,GuilhermeVielmo,AndréiaRolim,Verônica MachadoGonçalves,Maiara AlineCibulski,Samuel PauloSnel,GustavoMayer,Fabiana QuoosVargas,Agueda Castagna deDriemeier,DavidPavarini,Saulo Petinattieng2020-10-20T00:00:00ZRevista |
dc.title.none.fl_str_mv |
Bovine abortion by a vaccine strain of Bacillus anthracis |
title |
Bovine abortion by a vaccine strain of Bacillus anthracis |
spellingShingle |
Bovine abortion by a vaccine strain of Bacillus anthracis Bassuino,Daniele Mariath anthrax cattle fetal loss infectious diseases |
title_short |
Bovine abortion by a vaccine strain of Bacillus anthracis |
title_full |
Bovine abortion by a vaccine strain of Bacillus anthracis |
title_fullStr |
Bovine abortion by a vaccine strain of Bacillus anthracis |
title_full_unstemmed |
Bovine abortion by a vaccine strain of Bacillus anthracis |
title_sort |
Bovine abortion by a vaccine strain of Bacillus anthracis |
author |
Bassuino,Daniele Mariath |
author_facet |
Bassuino,Daniele Mariath Siqueira,Franciele Maboni Konradt,Guilherme Vielmo,Andréia Rolim,Verônica Machado Gonçalves,Maiara Aline Cibulski,Samuel Paulo Snel,Gustavo Mayer,Fabiana Quoos Vargas,Agueda Castagna de Driemeier,David Pavarini,Saulo Petinatti |
author_role |
author |
author2 |
Siqueira,Franciele Maboni Konradt,Guilherme Vielmo,Andréia Rolim,Verônica Machado Gonçalves,Maiara Aline Cibulski,Samuel Paulo Snel,Gustavo Mayer,Fabiana Quoos Vargas,Agueda Castagna de Driemeier,David Pavarini,Saulo Petinatti |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Bassuino,Daniele Mariath Siqueira,Franciele Maboni Konradt,Guilherme Vielmo,Andréia Rolim,Verônica Machado Gonçalves,Maiara Aline Cibulski,Samuel Paulo Snel,Gustavo Mayer,Fabiana Quoos Vargas,Agueda Castagna de Driemeier,David Pavarini,Saulo Petinatti |
dc.subject.por.fl_str_mv |
anthrax cattle fetal loss infectious diseases |
topic |
anthrax cattle fetal loss infectious diseases |
description |
ABSTRACT: This paper reports the abortion of a male Aberdeen Angus bovine by a vaccine strain of Bacillus anthracis, describing the pathological and microbiological findings and the genome sequence. Necropsy findings included multifocal areas of hemorrhage in different organs. Histologically, various organs showed hemorrhage, fibrin exudation, necrosis associated with countless bacillary bacterial clumps and severe neutrophilic inflammatory infiltrate. In the microbiological examination, numerous rough, nonhemolytic, gray and dry colonies with irregular edges were isolated from liver, lung and abomasum content samples. Gram staining revealed square-ended Gram-positive rods arranged in chains. B. anthracis identification was confirmed by detection of the molecular chromosomal marker Ba813. The genomes from the isolated B. anthracis (named SPV842_15) and from the isolated vaccinal strain (Brazilian vaccinal strain), which was recovered from a commercial vaccine used in the pregnant cow, were sequenced. Genomic comparisons displayed a high level of nucleotide identity in the comparisons between B. anthracis SPV842_15 and the B. anthracis Brazilian vaccinal strain (98,2%). Furthermore, in both strains, only the plasmid pX01 sequence was detected. Although, vaccination against anthrax is characterized by an elevated protective profile and very low residual virulence, immunization with Sterne strains can cause abortion in cattle, presumably by the plasmid pX01 toxins in rare or special situations. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020001200554 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020001200554 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0103-8478cr20200264 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
dc.source.none.fl_str_mv |
Ciência Rural v.50 n.12 2020 reponame:Ciência Rural instname:Universidade Federal de Santa Maria (UFSM) instacron:UFSM |
instname_str |
Universidade Federal de Santa Maria (UFSM) |
instacron_str |
UFSM |
institution |
UFSM |
reponame_str |
Ciência Rural |
collection |
Ciência Rural |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1749140555238998016 |