Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS

Detalhes bibliográficos
Autor(a) principal: Flores, Clóvis Blattes
Data de Publicação: 2015
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Manancial - Repositório Digital da UFSM
dARK ID: ark:/26339/001300000jbgg
Texto Completo: http://repositorio.ufsm.br/handle/1/9032
Resumo: Bone fragility caused by osteoporosis has increased the incidence of low-impact fractures in postmenopausal women. It represents a serious Public Health problem due to its increased risk of new fractures, high morbidity, and high mortality. Furthermore, it has a considerable impact in the treatment costs. The objective of this study was to evaluate the prevalence of pharmacological treatment for prevention of bone fractures in post-menopause women with the diagnosis of osteoporosis, in Santa Maria, Rio Grande do Sul. A cross-sectional study was carried out between March 1st and August 31st 2013. It included, in total, 1,057 postmenopausal women, aged 55 or over, who attended the basic health unit (UBS) in their region. Women with difficulties of communication and/or still menstruating were excluded. Data were obtained through questionnaires with information regarding patient s characteristics, lifestyle habits, history of fractures, risk factors for fractures and use of medications. Low-impact fractures were defined as those resulting from a fall no greater than standing height. Results: From the 1,301 women invited to participate in the study, 1,057 were eligible. The mean age was 67.2 (7.6). Two hundred seventy eight women had a diagnosis of osteoporosis. A hundred and sixty women were diagnosed for osteoporosis through bone densitometry, and a hundred eighteen due to major fractures (hip, wrist, humerus or clinical vertebral) by low impact. First-line medications (alendronate, risedronate and pamidronate) were used in 26.1% of these women and second-line drugs (raloxifene, estrogen, calcitonin) were used in 4,3%. The women who received pharmacological treatment, 9,6% were treated with first line medication, and 1,7% were treated with second line medication. Conclusion: in spite of the dedicated efforts, the diagnosis and treatment of osteoporosis in Santa Maria are inadequate, with obstacles of all levels, from health care providers (physicians and nurses) to the patients themselves.
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spelling Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RSPrevalence of pharmacological treatment for prevention of bone fractures in women with osteoporosis in the city of Santa MariaOsteoporoseFraturasPós-menopausaFatores de riscoTratamentoPrevençãoOsteoporosisFracturesPost-menopauseRisk factorsTreatmentPreventionCNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIABone fragility caused by osteoporosis has increased the incidence of low-impact fractures in postmenopausal women. It represents a serious Public Health problem due to its increased risk of new fractures, high morbidity, and high mortality. Furthermore, it has a considerable impact in the treatment costs. The objective of this study was to evaluate the prevalence of pharmacological treatment for prevention of bone fractures in post-menopause women with the diagnosis of osteoporosis, in Santa Maria, Rio Grande do Sul. A cross-sectional study was carried out between March 1st and August 31st 2013. It included, in total, 1,057 postmenopausal women, aged 55 or over, who attended the basic health unit (UBS) in their region. Women with difficulties of communication and/or still menstruating were excluded. Data were obtained through questionnaires with information regarding patient s characteristics, lifestyle habits, history of fractures, risk factors for fractures and use of medications. Low-impact fractures were defined as those resulting from a fall no greater than standing height. Results: From the 1,301 women invited to participate in the study, 1,057 were eligible. The mean age was 67.2 (7.6). Two hundred seventy eight women had a diagnosis of osteoporosis. A hundred and sixty women were diagnosed for osteoporosis through bone densitometry, and a hundred eighteen due to major fractures (hip, wrist, humerus or clinical vertebral) by low impact. First-line medications (alendronate, risedronate and pamidronate) were used in 26.1% of these women and second-line drugs (raloxifene, estrogen, calcitonin) were used in 4,3%. The women who received pharmacological treatment, 9,6% were treated with first line medication, and 1,7% were treated with second line medication. Conclusion: in spite of the dedicated efforts, the diagnosis and treatment of osteoporosis in Santa Maria are inadequate, with obstacles of all levels, from health care providers (physicians and nurses) to the patients themselves.A fragilidade óssea causada pela osteoporose aumentou a ocorrência de fraturas por baixo impacto em mulheres no período de pós-menopausa, representando um sério problema de Saúde Pública, já que aumenta os riscos de novas fraturas, morbidade, mortalidade, além de impactar nos custos do tratamento. O objetivo deste estudo é pesquisar a prevalência de tratamento farmacológico para prevenção de fraturas ósseas na pós-menopausa com diagnóstico de osteoporose, no município de Santa Maria RS. Este é um estudo transversal, realizado no período de 01 de março a 31 de agosto de 2013. No total foram incluídas 1.057 mulheres com idade igual ou superior a 55 anos, na pós-menopausa, e que frequentassem a unidade básica de saúde (UBS) de seu território. Mulheres com dificuldade de comunicação e que ainda menstruassem foram excluídas. Os dados foram obtidos através de questionários contendo informações relacionadas às características da paciente, hábitos de vida, história de fraturas, fatores de risco para faturas e uso de medicações. Fraturas de baixo impacto foram definidas como aquelas decorrentes da queda da própria altura ou menos. Resultados: Dentre as 1.301 mulheres convidadas a participar do estudo, 1.057 foram elegíveis. Sua média de idade foi 67,2 anos (7,6). Duzentas e setenta e oito mulheres apresentavam o diagnóstico de osteoporose. Cento e sessenta mulheres foram diagnosticadas através do exame de densitometria óssea, e cento e dezoito pela presença de fraturas maiores (quadril, punho, ombro ou vertebral clínica) por trauma mínimo. Medicamentos de primeira linha (alendronato, risedronato e pamidronato) foram utilizados em 26,1% das mulheres diagnosticadas pela densitometria mineral óssea (DMO), e de segunda linha (raloxifeno, estrogênio, calcitonina) em 4,3%. Das mulheres diagnosticadas com fratura maior, 9,6% foram tratadas com medicamentos de primeira linha, e 1,7% com medicamentos de segunda linha. Conclusão: apesar dos esforços dispensados o diagnóstico e tratamento da osteoporose no município de Santa Maria não são adequados, com obstáculos de todos os níveis, desde os provedores de cuidados de saúde (médicos e enfermeiros), até os próprios pacientes.Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em FarmacologiaPremaor, Melissa Orlandinhttp://lattes.cnpq.br/1919693261808995Comim, Fabio Vasconcelloshttp://lattes.cnpq.br/5119233991388822Fagundes, Renato Borgeshttp://lattes.cnpq.br/5255286815018611Cruz, Ivana Beatrice Mânica dahttp://lattes.cnpq.br/3426369324110716Flores, Clóvis Blattes2016-11-082016-11-082015-04-07info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfapplication/pdfFLORES, Clóvis Blattes. Prevalence of pharmacological treatment for prevention of bone fractures in women with osteoporosis in the city of Santa Maria. 2015. 42 f. Dissertação (Mestrado em Farmácia) - Universidade Federal de Santa Maria, Santa Maria, 2015.http://repositorio.ufsm.br/handle/1/9032ark:/26339/001300000jbggporinfo:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2022-05-04T14:03:28Zoai:repositorio.ufsm.br:1/9032Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2022-05-04T14:03:28Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS
Prevalence of pharmacological treatment for prevention of bone fractures in women with osteoporosis in the city of Santa Maria
title Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS
spellingShingle Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS
Flores, Clóvis Blattes
Osteoporose
Fraturas
Pós-menopausa
Fatores de risco
Tratamento
Prevenção
Osteoporosis
Fractures
Post-menopause
Risk factors
Treatment
Prevention
CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
title_short Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS
title_full Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS
title_fullStr Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS
title_full_unstemmed Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS
title_sort Prevalência de tratamento farmacológico para prevenção de fraturas ósseas em mulheres com osteoporose no município de Santa Maria - RS
author Flores, Clóvis Blattes
author_facet Flores, Clóvis Blattes
author_role author
dc.contributor.none.fl_str_mv Premaor, Melissa Orlandin
http://lattes.cnpq.br/1919693261808995
Comim, Fabio Vasconcellos
http://lattes.cnpq.br/5119233991388822
Fagundes, Renato Borges
http://lattes.cnpq.br/5255286815018611
Cruz, Ivana Beatrice Mânica da
http://lattes.cnpq.br/3426369324110716
dc.contributor.author.fl_str_mv Flores, Clóvis Blattes
dc.subject.por.fl_str_mv Osteoporose
Fraturas
Pós-menopausa
Fatores de risco
Tratamento
Prevenção
Osteoporosis
Fractures
Post-menopause
Risk factors
Treatment
Prevention
CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
topic Osteoporose
Fraturas
Pós-menopausa
Fatores de risco
Tratamento
Prevenção
Osteoporosis
Fractures
Post-menopause
Risk factors
Treatment
Prevention
CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
description Bone fragility caused by osteoporosis has increased the incidence of low-impact fractures in postmenopausal women. It represents a serious Public Health problem due to its increased risk of new fractures, high morbidity, and high mortality. Furthermore, it has a considerable impact in the treatment costs. The objective of this study was to evaluate the prevalence of pharmacological treatment for prevention of bone fractures in post-menopause women with the diagnosis of osteoporosis, in Santa Maria, Rio Grande do Sul. A cross-sectional study was carried out between March 1st and August 31st 2013. It included, in total, 1,057 postmenopausal women, aged 55 or over, who attended the basic health unit (UBS) in their region. Women with difficulties of communication and/or still menstruating were excluded. Data were obtained through questionnaires with information regarding patient s characteristics, lifestyle habits, history of fractures, risk factors for fractures and use of medications. Low-impact fractures were defined as those resulting from a fall no greater than standing height. Results: From the 1,301 women invited to participate in the study, 1,057 were eligible. The mean age was 67.2 (7.6). Two hundred seventy eight women had a diagnosis of osteoporosis. A hundred and sixty women were diagnosed for osteoporosis through bone densitometry, and a hundred eighteen due to major fractures (hip, wrist, humerus or clinical vertebral) by low impact. First-line medications (alendronate, risedronate and pamidronate) were used in 26.1% of these women and second-line drugs (raloxifene, estrogen, calcitonin) were used in 4,3%. The women who received pharmacological treatment, 9,6% were treated with first line medication, and 1,7% were treated with second line medication. Conclusion: in spite of the dedicated efforts, the diagnosis and treatment of osteoporosis in Santa Maria are inadequate, with obstacles of all levels, from health care providers (physicians and nurses) to the patients themselves.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-07
2016-11-08
2016-11-08
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv FLORES, Clóvis Blattes. Prevalence of pharmacological treatment for prevention of bone fractures in women with osteoporosis in the city of Santa Maria. 2015. 42 f. Dissertação (Mestrado em Farmácia) - Universidade Federal de Santa Maria, Santa Maria, 2015.
http://repositorio.ufsm.br/handle/1/9032
dc.identifier.dark.fl_str_mv ark:/26339/001300000jbgg
identifier_str_mv FLORES, Clóvis Blattes. Prevalence of pharmacological treatment for prevention of bone fractures in women with osteoporosis in the city of Santa Maria. 2015. 42 f. Dissertação (Mestrado em Farmácia) - Universidade Federal de Santa Maria, Santa Maria, 2015.
ark:/26339/001300000jbgg
url http://repositorio.ufsm.br/handle/1/9032
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
BR
Farmacologia
UFSM
Programa de Pós-Graduação em Farmacologia
publisher.none.fl_str_mv Universidade Federal de Santa Maria
BR
Farmacologia
UFSM
Programa de Pós-Graduação em Farmacologia
dc.source.none.fl_str_mv reponame:Manancial - Repositório Digital da UFSM
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Manancial - Repositório Digital da UFSM
collection Manancial - Repositório Digital da UFSM
repository.name.fl_str_mv Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv atendimento.sib@ufsm.br||tedebc@gmail.com
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