Clonidina ou sufentanil epidural em cães submetidos à ovário-histerectomia

• Autor(a) principal: Bopp, Simone
• Data de Publicação: 2004
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações do UFSM
• Texto Completo: http://repositorio.ufsm.br/handle/1/10103
• topic: Analgesia; Opióides; Agonistas alfa2 adrenérgicos; CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA

The objective of this study was to evaluate the cardiovascular, respiratory and analgesic effects of epidural clonidine and sufentanil associated with halothane anesthesia and in the immediate postoperative period. In order to study this, twenty female dogs, healthy, among 10 to 20 kg from the routine of Veterinary Hospital of UFSM underwent ovario-histerectomy. The dogs were distributed in two groups. One received epidural clonidine and other received epidural sufentanil. In the P0 period (baseline values), heart rate (HR), systolic arterial pressure (SAP), hemoglobin saturation (SatO2), respiratory rate (RR) and temperature (T°C) were measured, also heart rhythm was evaluate and collected the first sample of arterial blood to gas analysis (P0G). Two another samples of arterial blood were collected, one 30 minutes after epidural (P1G) and other four hours after epidural (P2G) to analyze pH, parcial arterial press of CO2 (PaCO2), parcial arterial press of O2 (PaO2), hemoglobin saturation (SatO2), base excess (BE), bicarbonate (HCO3) and total CO2 (TCO2). In the P1 (15 minutes after epidural) and in the other periods (P2, P3 and P4 at 15 minutes intervals until the end of the procedure) were measured HR, RR, SatO2,, SAP, tidal volume (VT) and minute ventilation (VE), heart rhythm, T°C and halothane concentration release from the vaporizator (V%). As for the level anesthetic, 0,5 to 1 V% were diminished in each measure. Passed one hour to the end of the surgery was realizated the first pospoperative avaliation of analgesia, repeated each hour during five hours of postoperative by the modificated Firth&Haldane scale. The results show that epidural clonidine and epidural sufentanil provide adequated intra-operative analgesia with minimal cardiovascular and respiratory effects associated with halothane anesthesia in dogs undergoing ovario-histerectomy and adequate analgesia in the immediate postoperative period, with sufentanil exhibiting lesser punctuation by the scores obtained by the modificated Firth&Haldane scale