The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2006 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNIFESP |
| dARK ID: | ark:/48912/0013000010h0r |
| DOI: | 10.1590/S0102-86502006000500010 |
| Texto Completo: | http://dx.doi.org/10.1590/S0102-86502006000500010 http://repositorio.unifesp.br/handle/11600/3273 |
Resumo: | PURPOSE: To assess the role of preserved bovine parietal peritoneum as a material for hernia repair in a rat ventral hernia model. METHODS: An abdominal wall defect (15mm x 25mm) was created in Wistar male rats (n=40). Control animals (n=20) had the polypropylene (PP) mesh sutured into the defect, whereas bovine preserved peritoneum (BPP) was used in experimental group (n=20). After 7 and 28 days, the abdominal wall was taken off and histological studies of the amount of collagen by Sirius Red stain and morphometric evaluation consisted in quantitative analysis of the collagen by using specific software (Imagelab®). The Mann-Whitney, Kruskal-Wallis and ANOVA tests were applied for statistical analysis (pd0.05). RESULTS: Histological examination revealed no difference between the BPP and PP groups (p = 0.55 NS). CONCLUSION: BPP is suitable for the closure of ventral hernias in rat model as shown by its morphological properties. |
| id |
UFSP_10b1790088938d96484ee4b7725e517b |
|---|---|
| oai_identifier_str |
oai:repositorio.unifesp.br/:11600/3273 |
| network_acronym_str |
UFSP |
| network_name_str |
Repositório Institucional da UNIFESP |
| repository_id_str |
3465 |
| spelling |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluationAspectos histológicos do uso do peritônio bovino conservado na correção de hérnia ventral em ratosHernia, VentralPeritoneum. SurgicalMeshHérnia VentralPeritnioTelas CirúrgicasPURPOSE: To assess the role of preserved bovine parietal peritoneum as a material for hernia repair in a rat ventral hernia model. METHODS: An abdominal wall defect (15mm x 25mm) was created in Wistar male rats (n=40). Control animals (n=20) had the polypropylene (PP) mesh sutured into the defect, whereas bovine preserved peritoneum (BPP) was used in experimental group (n=20). After 7 and 28 days, the abdominal wall was taken off and histological studies of the amount of collagen by Sirius Red stain and morphometric evaluation consisted in quantitative analysis of the collagen by using specific software (Imagelab®). The Mann-Whitney, Kruskal-Wallis and ANOVA tests were applied for statistical analysis (pd0.05). RESULTS: Histological examination revealed no difference between the BPP and PP groups (p = 0.55 NS). CONCLUSION: BPP is suitable for the closure of ventral hernias in rat model as shown by its morphological properties.OBJETIVO: Estudar os aspectos histológicos do uso de uma prótese de peritônio bovino na correção de hérnia ventral em um modelo animal de doença. MÉTODOS: Utilizando 40 ratos machos Wistar, comparou-se o implante do peritônio bovino com a tela de polipropileno na correção de um defeito provocado na parede abdominal do animal. Após 7 (sub-grupo A) e 28 (sub-grupo B) dias de observação, as peças foram retiradas e procedeu-se o estudo histológico através da quantificação de colágeno pelo método de captação e processamento digital de imagens, sob a coloração do Sirius Red. Os testes de Mann-Whitney, de Kruskal-Wallis e ANOVA foram utilizados e estabeleceu-se em 0,05 o nível para rejeição da hipótese de nulidade (pd0.05). RESULTADOS: A quantificação do colágeno na interface do implante mostrou equivalência entre os grupos Peritônio e Polipropileno (p=0,55 NS). CONCLUSÃO: O peritônio parietal bovino apresentou infiltração de tecido fibrocolágeno semelhante a da tela de polipropileno na correção de hérnia ventral em ratos.Marilia Medicine School Department of SurgeryUNIFESPUniversidade Federal de São Paulo (UNIFESP) Department of SurgeryUNIFESP, Department of SurgerySciELOSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaMarilia Medicine School Department of SurgeryUniversidade Federal de São Paulo (UNIFESP)Bastos, Eduardo Lemos de SouzaFagundes, Djalma José [UNIFESP]Taha, Murched Omar [UNIFESP]Novo, Neil Ferreira [UNIFESP]Juliano, Yara [UNIFESP]Simões, Manuel de Jesus [UNIFESP]Silvado, Rubens Augusto Brazil [UNIFESP]2015-06-14T13:36:27Z2015-06-14T13:36:27Z2006-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion328-331application/pdfhttp://dx.doi.org/10.1590/S0102-86502006000500010Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 21, n. 5, p. 328-331, 2006.10.1590/S0102-86502006000500010S0102-86502006000500010.pdf0102-8650S0102-86502006000500010http://repositorio.unifesp.br/handle/11600/3273ark:/48912/0013000010h0rengActa Cirurgica Brasileirainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-28T18:08:28Zoai:repositorio.unifesp.br/:11600/3273Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:47:33.852663Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
| dc.title.none.fl_str_mv |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation Aspectos histológicos do uso do peritônio bovino conservado na correção de hérnia ventral em ratos |
| title |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation |
| spellingShingle |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation Bastos, Eduardo Lemos de Souza Hernia, Ventral Peritoneum. Surgical Mesh Hérnia Ventral Peritnio Telas Cirúrgicas Bastos, Eduardo Lemos de Souza Hernia, Ventral Peritoneum. Surgical Mesh Hérnia Ventral Peritnio Telas Cirúrgicas |
| title_short |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation |
| title_full |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation |
| title_fullStr |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation |
| title_full_unstemmed |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation |
| title_sort |
The role of bovine preserved peritoneum in rats ventral hernia: a histological evaluation |
| author |
Bastos, Eduardo Lemos de Souza |
| author_facet |
Bastos, Eduardo Lemos de Souza Bastos, Eduardo Lemos de Souza Fagundes, Djalma José [UNIFESP] Taha, Murched Omar [UNIFESP] Novo, Neil Ferreira [UNIFESP] Juliano, Yara [UNIFESP] Simões, Manuel de Jesus [UNIFESP] Silvado, Rubens Augusto Brazil [UNIFESP] Fagundes, Djalma José [UNIFESP] Taha, Murched Omar [UNIFESP] Novo, Neil Ferreira [UNIFESP] Juliano, Yara [UNIFESP] Simões, Manuel de Jesus [UNIFESP] Silvado, Rubens Augusto Brazil [UNIFESP] |
| author_role |
author |
| author2 |
Fagundes, Djalma José [UNIFESP] Taha, Murched Omar [UNIFESP] Novo, Neil Ferreira [UNIFESP] Juliano, Yara [UNIFESP] Simões, Manuel de Jesus [UNIFESP] Silvado, Rubens Augusto Brazil [UNIFESP] |
| author2_role |
author author author author author author |
| dc.contributor.none.fl_str_mv |
Marilia Medicine School Department of Surgery Universidade Federal de São Paulo (UNIFESP) |
| dc.contributor.author.fl_str_mv |
Bastos, Eduardo Lemos de Souza Fagundes, Djalma José [UNIFESP] Taha, Murched Omar [UNIFESP] Novo, Neil Ferreira [UNIFESP] Juliano, Yara [UNIFESP] Simões, Manuel de Jesus [UNIFESP] Silvado, Rubens Augusto Brazil [UNIFESP] |
| dc.subject.por.fl_str_mv |
Hernia, Ventral Peritoneum. Surgical Mesh Hérnia Ventral Peritnio Telas Cirúrgicas |
| topic |
Hernia, Ventral Peritoneum. Surgical Mesh Hérnia Ventral Peritnio Telas Cirúrgicas |
| description |
PURPOSE: To assess the role of preserved bovine parietal peritoneum as a material for hernia repair in a rat ventral hernia model. METHODS: An abdominal wall defect (15mm x 25mm) was created in Wistar male rats (n=40). Control animals (n=20) had the polypropylene (PP) mesh sutured into the defect, whereas bovine preserved peritoneum (BPP) was used in experimental group (n=20). After 7 and 28 days, the abdominal wall was taken off and histological studies of the amount of collagen by Sirius Red stain and morphometric evaluation consisted in quantitative analysis of the collagen by using specific software (Imagelab®). The Mann-Whitney, Kruskal-Wallis and ANOVA tests were applied for statistical analysis (pd0.05). RESULTS: Histological examination revealed no difference between the BPP and PP groups (p = 0.55 NS). CONCLUSION: BPP is suitable for the closure of ventral hernias in rat model as shown by its morphological properties. |
| publishDate |
2006 |
| dc.date.none.fl_str_mv |
2006-10-01 2015-06-14T13:36:27Z 2015-06-14T13:36:27Z |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0102-86502006000500010 Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 21, n. 5, p. 328-331, 2006. 10.1590/S0102-86502006000500010 S0102-86502006000500010.pdf 0102-8650 S0102-86502006000500010 http://repositorio.unifesp.br/handle/11600/3273 |
| dc.identifier.dark.fl_str_mv |
ark:/48912/0013000010h0r |
| url |
http://dx.doi.org/10.1590/S0102-86502006000500010 http://repositorio.unifesp.br/handle/11600/3273 |
| identifier_str_mv |
Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 21, n. 5, p. 328-331, 2006. 10.1590/S0102-86502006000500010 S0102-86502006000500010.pdf 0102-8650 S0102-86502006000500010 ark:/48912/0013000010h0r |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Acta Cirurgica Brasileira |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
328-331 application/pdf |
| dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
| publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
| instname_str |
Universidade Federal de São Paulo (UNIFESP) |
| instacron_str |
UNIFESP |
| institution |
UNIFESP |
| reponame_str |
Repositório Institucional da UNIFESP |
| collection |
Repositório Institucional da UNIFESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
| repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
| _version_ |
1822183974460456960 |
| dc.identifier.doi.none.fl_str_mv |
10.1590/S0102-86502006000500010 |