Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012

Detalhes bibliográficos
Autor(a) principal: Pereira, Carlos Alberto de Castro [UNIFESP]
Data de Publicação: 2014
Outros Autores: Duarte, Andrezza Araujo Oliveira, Gimenez, Andrea, Soares, Maria Raquel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S1806-37132014000400007
http://repositorio.unifesp.br/handle/11600/8527
Resumo: OBJECTIVE:To evaluate the spirometry values predicted by the 2012 Global Lung Function Initiative (GLI) equations, which are recommended for international use, in comparison with those obtained for a sample of White adults used for the establishment of reference equations for spirometry in Brazil.METHODS:The sample comprised 270 and 373 healthy males and females, respectively. The mean differences between the values found in this sample and the predicted values calculated from the GLI equations for FVC, FEV1, and VEF1/FVC, as well as their lower limits, were compared by paired t-test. The predicted values by each pair of equations were compared in various combinations of age and height.RESULTS:For the males in our study sample, the values obtained for all of the variables studied were significantly higher than those predicted by the GLI equations (p < 0.01 for all). These differences become more evident in subjects who were shorter in stature and older. For the females in our study sample, only the lower limit of the FEV1/FVC ratio was significantly higher than that predicted by the GLI equation.CONCLUSIONS:The predicted values suggested by the GLI equations for White adults were significantly lower than those used as reference values for males in Brazil. For both genders, the lower limit of the FEV1/FVC ratio is significantly lower than that predicted by the GLI equations.
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spelling Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012Comparação entre os valores de referência para CVF, VEF1 e relação VEF1/CVF em brasileiros caucasianos adultos e aqueles sugeridos pela Global Lung Function Initiative 2012Respiratory function tests/statistics and numerical dataRespiratory function tests/diagnosisReference valuesTestes de função respiratória/estatística e dados numéricosTestes de função respiratória/diagnósticoValores de referênciaOBJECTIVE:To evaluate the spirometry values predicted by the 2012 Global Lung Function Initiative (GLI) equations, which are recommended for international use, in comparison with those obtained for a sample of White adults used for the establishment of reference equations for spirometry in Brazil.METHODS:The sample comprised 270 and 373 healthy males and females, respectively. The mean differences between the values found in this sample and the predicted values calculated from the GLI equations for FVC, FEV1, and VEF1/FVC, as well as their lower limits, were compared by paired t-test. The predicted values by each pair of equations were compared in various combinations of age and height.RESULTS:For the males in our study sample, the values obtained for all of the variables studied were significantly higher than those predicted by the GLI equations (p < 0.01 for all). These differences become more evident in subjects who were shorter in stature and older. For the females in our study sample, only the lower limit of the FEV1/FVC ratio was significantly higher than that predicted by the GLI equation.CONCLUSIONS:The predicted values suggested by the GLI equations for White adults were significantly lower than those used as reference values for males in Brazil. For both genders, the lower limit of the FEV1/FVC ratio is significantly lower than that predicted by the GLI equations.OBJETIVO:Comparar os valores espirométricos previstos pelas equações da Global Lung Function Initiative (GLI) em 2012, sugeridas como de uso internacional, com aqueles obtidos em uma amostra utilizada para derivação de valores de referência em adultos caucasianos brasileiros.MÉTODOS:A amostra utilizada era composta por 270 homens e 373 mulheres saudáveis. As médias das diferenças entre os valores dessa amostra e os valores previstos calculados a partir das equações da GLI para CVF, VEF1 e VEF1/CVF, assim como seus limites inferiores, foram comparados por teste de t pareado. Os valores previstos pelos pares das equações foram comparados em diversas combinações de idade e estatura.RESULTADOS:Nos homens da amostra, os valores obtidos para todas as variáveis estudadas foram significativamente maiores que aqueles previstos pelas equações da GLI (p < 0,01 para todas). Estas diferenças se tornaram mais evidentes em indivíduos com menor estatura e idade mais avançada. Nas mulheres, somente o limite inferior da relação VEF1/CVF foi significativamente maior na amostra brasileira.CONCLUSÕES:Os valores previstos sugeridos pelas equações da GLI para caucasianos são significativamente menores daqueles utilizados como referência para homens brasileiros. Em ambos os sexos, o limite inferior da relação VEF1/CVF é significativamente menor que o previsto pelas equações GLIFederal University of São PauloFederal University of Campina GrandeCentro Diagnóstico BrasilUNIFESPSciELOSociedade Brasileira de Pneumologia e TisiologiaUniversidade Federal de São Paulo (UNIFESP)Federal University of Campina GrandeCentro Diagnóstico BrasilPereira, Carlos Alberto de Castro [UNIFESP]Duarte, Andrezza Araujo OliveiraGimenez, AndreaSoares, Maria Raquel2015-06-14T13:47:14Z2015-06-14T13:47:14Z2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion397-402application/pdfhttp://dx.doi.org/10.1590/S1806-37132014000400007Jornal Brasileiro de Pneumologia. Sociedade Brasileira de Pneumologia e Tisiologia, v. 40, n. 4, p. 397-402, 2014.10.1590/S1806-37132014000400007S1806-37132014000400397.pdf1806-3713S1806-37132014000400397http://repositorio.unifesp.br/handle/11600/8527engJornal Brasileiro de Pneumologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-30T03:23:37Zoai:repositorio.unifesp.br/:11600/8527Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-30T03:23:37Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
Comparação entre os valores de referência para CVF, VEF1 e relação VEF1/CVF em brasileiros caucasianos adultos e aqueles sugeridos pela Global Lung Function Initiative 2012
title Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
spellingShingle Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
Pereira, Carlos Alberto de Castro [UNIFESP]
Respiratory function tests/statistics and numerical data
Respiratory function tests/diagnosis
Reference values
Testes de função respiratória/estatística e dados numéricos
Testes de função respiratória/diagnóstico
Valores de referência
title_short Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
title_full Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
title_fullStr Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
title_full_unstemmed Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
title_sort Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
author Pereira, Carlos Alberto de Castro [UNIFESP]
author_facet Pereira, Carlos Alberto de Castro [UNIFESP]
Duarte, Andrezza Araujo Oliveira
Gimenez, Andrea
Soares, Maria Raquel
author_role author
author2 Duarte, Andrezza Araujo Oliveira
Gimenez, Andrea
Soares, Maria Raquel
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Federal University of Campina Grande
Centro Diagnóstico Brasil
dc.contributor.author.fl_str_mv Pereira, Carlos Alberto de Castro [UNIFESP]
Duarte, Andrezza Araujo Oliveira
Gimenez, Andrea
Soares, Maria Raquel
dc.subject.por.fl_str_mv Respiratory function tests/statistics and numerical data
Respiratory function tests/diagnosis
Reference values
Testes de função respiratória/estatística e dados numéricos
Testes de função respiratória/diagnóstico
Valores de referência
topic Respiratory function tests/statistics and numerical data
Respiratory function tests/diagnosis
Reference values
Testes de função respiratória/estatística e dados numéricos
Testes de função respiratória/diagnóstico
Valores de referência
description OBJECTIVE:To evaluate the spirometry values predicted by the 2012 Global Lung Function Initiative (GLI) equations, which are recommended for international use, in comparison with those obtained for a sample of White adults used for the establishment of reference equations for spirometry in Brazil.METHODS:The sample comprised 270 and 373 healthy males and females, respectively. The mean differences between the values found in this sample and the predicted values calculated from the GLI equations for FVC, FEV1, and VEF1/FVC, as well as their lower limits, were compared by paired t-test. The predicted values by each pair of equations were compared in various combinations of age and height.RESULTS:For the males in our study sample, the values obtained for all of the variables studied were significantly higher than those predicted by the GLI equations (p < 0.01 for all). These differences become more evident in subjects who were shorter in stature and older. For the females in our study sample, only the lower limit of the FEV1/FVC ratio was significantly higher than that predicted by the GLI equation.CONCLUSIONS:The predicted values suggested by the GLI equations for White adults were significantly lower than those used as reference values for males in Brazil. For both genders, the lower limit of the FEV1/FVC ratio is significantly lower than that predicted by the GLI equations.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-01
2015-06-14T13:47:14Z
2015-06-14T13:47:14Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1806-37132014000400007
Jornal Brasileiro de Pneumologia. Sociedade Brasileira de Pneumologia e Tisiologia, v. 40, n. 4, p. 397-402, 2014.
10.1590/S1806-37132014000400007
S1806-37132014000400397.pdf
1806-3713
S1806-37132014000400397
http://repositorio.unifesp.br/handle/11600/8527
url http://dx.doi.org/10.1590/S1806-37132014000400007
http://repositorio.unifesp.br/handle/11600/8527
identifier_str_mv Jornal Brasileiro de Pneumologia. Sociedade Brasileira de Pneumologia e Tisiologia, v. 40, n. 4, p. 397-402, 2014.
10.1590/S1806-37132014000400007
S1806-37132014000400397.pdf
1806-3713
S1806-37132014000400397
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Jornal Brasileiro de Pneumologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 397-402
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pneumologia e Tisiologia
publisher.none.fl_str_mv Sociedade Brasileira de Pneumologia e Tisiologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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