Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S1806-37132014000400007 http://repositorio.unifesp.br/handle/11600/8527 |
Resumo: | OBJECTIVE:To evaluate the spirometry values predicted by the 2012 Global Lung Function Initiative (GLI) equations, which are recommended for international use, in comparison with those obtained for a sample of White adults used for the establishment of reference equations for spirometry in Brazil.METHODS:The sample comprised 270 and 373 healthy males and females, respectively. The mean differences between the values found in this sample and the predicted values calculated from the GLI equations for FVC, FEV1, and VEF1/FVC, as well as their lower limits, were compared by paired t-test. The predicted values by each pair of equations were compared in various combinations of age and height.RESULTS:For the males in our study sample, the values obtained for all of the variables studied were significantly higher than those predicted by the GLI equations (p < 0.01 for all). These differences become more evident in subjects who were shorter in stature and older. For the females in our study sample, only the lower limit of the FEV1/FVC ratio was significantly higher than that predicted by the GLI equation.CONCLUSIONS:The predicted values suggested by the GLI equations for White adults were significantly lower than those used as reference values for males in Brazil. For both genders, the lower limit of the FEV1/FVC ratio is significantly lower than that predicted by the GLI equations. |
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Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012Comparação entre os valores de referência para CVF, VEF1 e relação VEF1/CVF em brasileiros caucasianos adultos e aqueles sugeridos pela Global Lung Function Initiative 2012Respiratory function tests/statistics and numerical dataRespiratory function tests/diagnosisReference valuesTestes de função respiratória/estatística e dados numéricosTestes de função respiratória/diagnósticoValores de referênciaOBJECTIVE:To evaluate the spirometry values predicted by the 2012 Global Lung Function Initiative (GLI) equations, which are recommended for international use, in comparison with those obtained for a sample of White adults used for the establishment of reference equations for spirometry in Brazil.METHODS:The sample comprised 270 and 373 healthy males and females, respectively. The mean differences between the values found in this sample and the predicted values calculated from the GLI equations for FVC, FEV1, and VEF1/FVC, as well as their lower limits, were compared by paired t-test. The predicted values by each pair of equations were compared in various combinations of age and height.RESULTS:For the males in our study sample, the values obtained for all of the variables studied were significantly higher than those predicted by the GLI equations (p < 0.01 for all). These differences become more evident in subjects who were shorter in stature and older. For the females in our study sample, only the lower limit of the FEV1/FVC ratio was significantly higher than that predicted by the GLI equation.CONCLUSIONS:The predicted values suggested by the GLI equations for White adults were significantly lower than those used as reference values for males in Brazil. For both genders, the lower limit of the FEV1/FVC ratio is significantly lower than that predicted by the GLI equations.OBJETIVO:Comparar os valores espirométricos previstos pelas equações da Global Lung Function Initiative (GLI) em 2012, sugeridas como de uso internacional, com aqueles obtidos em uma amostra utilizada para derivação de valores de referência em adultos caucasianos brasileiros.MÉTODOS:A amostra utilizada era composta por 270 homens e 373 mulheres saudáveis. As médias das diferenças entre os valores dessa amostra e os valores previstos calculados a partir das equações da GLI para CVF, VEF1 e VEF1/CVF, assim como seus limites inferiores, foram comparados por teste de t pareado. Os valores previstos pelos pares das equações foram comparados em diversas combinações de idade e estatura.RESULTADOS:Nos homens da amostra, os valores obtidos para todas as variáveis estudadas foram significativamente maiores que aqueles previstos pelas equações da GLI (p < 0,01 para todas). Estas diferenças se tornaram mais evidentes em indivíduos com menor estatura e idade mais avançada. Nas mulheres, somente o limite inferior da relação VEF1/CVF foi significativamente maior na amostra brasileira.CONCLUSÕES:Os valores previstos sugeridos pelas equações da GLI para caucasianos são significativamente menores daqueles utilizados como referência para homens brasileiros. Em ambos os sexos, o limite inferior da relação VEF1/CVF é significativamente menor que o previsto pelas equações GLIFederal University of São PauloFederal University of Campina GrandeCentro Diagnóstico BrasilUNIFESPSciELOSociedade Brasileira de Pneumologia e TisiologiaUniversidade Federal de São Paulo (UNIFESP)Federal University of Campina GrandeCentro Diagnóstico BrasilPereira, Carlos Alberto de Castro [UNIFESP]Duarte, Andrezza Araujo OliveiraGimenez, AndreaSoares, Maria Raquel2015-06-14T13:47:14Z2015-06-14T13:47:14Z2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion397-402application/pdfhttp://dx.doi.org/10.1590/S1806-37132014000400007Jornal Brasileiro de Pneumologia. Sociedade Brasileira de Pneumologia e Tisiologia, v. 40, n. 4, p. 397-402, 2014.10.1590/S1806-37132014000400007S1806-37132014000400397.pdf1806-3713S1806-37132014000400397http://repositorio.unifesp.br/handle/11600/8527engJornal Brasileiro de Pneumologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-30T03:23:37Zoai:repositorio.unifesp.br/:11600/8527Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-30T03:23:37Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012 Comparação entre os valores de referência para CVF, VEF1 e relação VEF1/CVF em brasileiros caucasianos adultos e aqueles sugeridos pela Global Lung Function Initiative 2012 |
title |
Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012 |
spellingShingle |
Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012 Pereira, Carlos Alberto de Castro [UNIFESP] Respiratory function tests/statistics and numerical data Respiratory function tests/diagnosis Reference values Testes de função respiratória/estatística e dados numéricos Testes de função respiratória/diagnóstico Valores de referência |
title_short |
Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012 |
title_full |
Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012 |
title_fullStr |
Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012 |
title_full_unstemmed |
Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012 |
title_sort |
Comparison between reference values for FVC, FEV1, and FEV1/FVC ratio in White adults in Brazil and those suggested by the Global Lung Function Initiative 2012 |
author |
Pereira, Carlos Alberto de Castro [UNIFESP] |
author_facet |
Pereira, Carlos Alberto de Castro [UNIFESP] Duarte, Andrezza Araujo Oliveira Gimenez, Andrea Soares, Maria Raquel |
author_role |
author |
author2 |
Duarte, Andrezza Araujo Oliveira Gimenez, Andrea Soares, Maria Raquel |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Federal University of Campina Grande Centro Diagnóstico Brasil |
dc.contributor.author.fl_str_mv |
Pereira, Carlos Alberto de Castro [UNIFESP] Duarte, Andrezza Araujo Oliveira Gimenez, Andrea Soares, Maria Raquel |
dc.subject.por.fl_str_mv |
Respiratory function tests/statistics and numerical data Respiratory function tests/diagnosis Reference values Testes de função respiratória/estatística e dados numéricos Testes de função respiratória/diagnóstico Valores de referência |
topic |
Respiratory function tests/statistics and numerical data Respiratory function tests/diagnosis Reference values Testes de função respiratória/estatística e dados numéricos Testes de função respiratória/diagnóstico Valores de referência |
description |
OBJECTIVE:To evaluate the spirometry values predicted by the 2012 Global Lung Function Initiative (GLI) equations, which are recommended for international use, in comparison with those obtained for a sample of White adults used for the establishment of reference equations for spirometry in Brazil.METHODS:The sample comprised 270 and 373 healthy males and females, respectively. The mean differences between the values found in this sample and the predicted values calculated from the GLI equations for FVC, FEV1, and VEF1/FVC, as well as their lower limits, were compared by paired t-test. The predicted values by each pair of equations were compared in various combinations of age and height.RESULTS:For the males in our study sample, the values obtained for all of the variables studied were significantly higher than those predicted by the GLI equations (p < 0.01 for all). These differences become more evident in subjects who were shorter in stature and older. For the females in our study sample, only the lower limit of the FEV1/FVC ratio was significantly higher than that predicted by the GLI equation.CONCLUSIONS:The predicted values suggested by the GLI equations for White adults were significantly lower than those used as reference values for males in Brazil. For both genders, the lower limit of the FEV1/FVC ratio is significantly lower than that predicted by the GLI equations. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-08-01 2015-06-14T13:47:14Z 2015-06-14T13:47:14Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1806-37132014000400007 Jornal Brasileiro de Pneumologia. Sociedade Brasileira de Pneumologia e Tisiologia, v. 40, n. 4, p. 397-402, 2014. 10.1590/S1806-37132014000400007 S1806-37132014000400397.pdf 1806-3713 S1806-37132014000400397 http://repositorio.unifesp.br/handle/11600/8527 |
url |
http://dx.doi.org/10.1590/S1806-37132014000400007 http://repositorio.unifesp.br/handle/11600/8527 |
identifier_str_mv |
Jornal Brasileiro de Pneumologia. Sociedade Brasileira de Pneumologia e Tisiologia, v. 40, n. 4, p. 397-402, 2014. 10.1590/S1806-37132014000400007 S1806-37132014000400397.pdf 1806-3713 S1806-37132014000400397 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Jornal Brasileiro de Pneumologia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
397-402 application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pneumologia e Tisiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pneumologia e Tisiologia |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268377893437440 |