Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNIFESP |
| Texto Completo: | http://dx.doi.org/10.1152/japplphysiol.00557.2016 https://repositorio.unifesp.br/handle/11600/56450 |
Resumo: | This study assessed 1) the effects of 12 wk of resistance training (RT) and resistance training with instability (RTI) on presynaptic inhibition (PSI) and disynaptic reciprocal inhibition (DRI) of patients with Parkinson's disease (PD) |
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3465 |
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Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's diseasemotor complexity exercisepresynaptic inhibitiondisynaptic reciprocal inhibitiondescending driveproprioceptionThis study assessed 1) the effects of 12 wk of resistance training (RT) and resistance training with instability (RTI) on presynaptic inhibition (PSI) and disynaptic reciprocal inhibition (DRI) of patients with Parkinson's disease (PD)2) the effectiveness of RT and RTI in moving PSI and DRI values of patients toward values of age-matched healthy controls (HCZ-score analysis)and 3) associations between PSI and DRI changes and clinical outcomes changes previously published. Thirteen patients in RT group, 13 in RTI group, and 11 in a nonexercising control group completed the trial. While RT and RTI groups performed resistance exercises twice a week for 12 wk, only the RTI group used unstable devices. The soleus H reflex was used to evaluate resting PSI and DRI before and after the experimental protocol. The HC (n = 31) was assessed at pretest only. There were significant group X time interactions for PSI (P < 0.0001) and DRI (P < 0.0001). RTI was more effective than RT in increasing the levels of PSI (P = 0.0154) and DRI (P < 0.0001) at posttraining and in moving PSI [confidence interval (CI) 0.1-0.5] and DRI (CI 0.6 -1.1) levels to those observed in HC. There was association between DRI and quality of life changes (r = -0.69, P = 0.008) and a strong trend toward association between PSI and postural instability changes (r = 0.60, P = 0.051) after RTI. RTI increased PSI and DRI levels more than RT, reaching the average values of the HC. Thus RTI may cause plastic changes in PSI and DRI pathways that are associated with some PD clinical outcomes. NEW & NOTEWORTHY Patients with Parkinson's disease (PD) have motor dysfunction. Spinal inhibitory mechanisms are important for modulating both supraspinal motor commands and sensory feedback at the spinal level. Resistance training with instability was more effective than resistance training in increasing the levels of presynaptic inhibition and disynaptic reciprocal inhibition of lower limb at rest of the patients with PD, reaching the average values of the healthy controls.Univ Sao Paulo, Sch Phys Educ & Sport, Lab Adaptat Strength Training, Sao Paulo, BrazilNorthwestern Univ, Dept Phys Therapy & Human Movement Sci, Chicago, IL 60611 USARush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL USANorthwestern Univ, Dept Physiol, Chicago, IL 60611 USAUniv Sao Paulo, Sch Phys Educ & Sport, Exercise Hemodynam Lab, Sao Paulo, BrazilUniv Sao Paulo, Fac Med Sci, Sao Paulo, BrazilUniv Fed Sao Paulo, Ctr Psychobiol & Exercise Studies, Dept Psychobiol, Sao Paulo, BrazilDepartment of Psychobiology, Center for Psychobiology and Exercise Studies, Universidade Federal de São Paulo (UNIFESP), São Paulo, BrazilWeb of ScienceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)FAPESP: 2011/042423FAPESP: 2012/03056-4FAPESP: 2013/04970-4CNPq: 304205/2011-7CNPq: 406609/2015-2CAPES: 3095/2015-00Amer Physiological Soc2020-07-31T12:46:54Z2020-07-31T12:46:54Z2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1-10http://dx.doi.org/10.1152/japplphysiol.00557.2016Journal Of Applied Physiology. Bethesda, v. 122, n. 1, p. 1-10, 2017.10.1152/japplphysiol.00557.20168750-7587https://repositorio.unifesp.br/handle/11600/56450WOS:000393698000001engJournal Of Applied PhysiologyBethesdainfo:eu-repo/semantics/openAccessSilva-Batista, CarlaTavares Mattos, Eugenia CasellaCorcos, Daniel M.Wilson, Jessica M.Heckman, Charles J.Kanegusuku, HelcioPimentel Piemonte, Maria ElisaMello, Marco Tulio de [UNIFESP]Forjaz, ClaudiaRoschel, HamiltonTricoli, ValmorUgrinowitsch, Carlosreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2021-10-05T21:34:59Zoai:repositorio.unifesp.br/:11600/56450Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652021-10-05T21:34:59Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
| dc.title.none.fl_str_mv |
Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease |
| title |
Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease |
| spellingShingle |
Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease Silva-Batista, Carla motor complexity exercise presynaptic inhibition disynaptic reciprocal inhibition descending drive proprioception |
| title_short |
Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease |
| title_full |
Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease |
| title_fullStr |
Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease |
| title_full_unstemmed |
Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease |
| title_sort |
Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease |
| author |
Silva-Batista, Carla |
| author_facet |
Silva-Batista, Carla Tavares Mattos, Eugenia Casella Corcos, Daniel M. Wilson, Jessica M. Heckman, Charles J. Kanegusuku, Helcio Pimentel Piemonte, Maria Elisa Mello, Marco Tulio de [UNIFESP] Forjaz, Claudia Roschel, Hamilton Tricoli, Valmor Ugrinowitsch, Carlos |
| author_role |
author |
| author2 |
Tavares Mattos, Eugenia Casella Corcos, Daniel M. Wilson, Jessica M. Heckman, Charles J. Kanegusuku, Helcio Pimentel Piemonte, Maria Elisa Mello, Marco Tulio de [UNIFESP] Forjaz, Claudia Roschel, Hamilton Tricoli, Valmor Ugrinowitsch, Carlos |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva-Batista, Carla Tavares Mattos, Eugenia Casella Corcos, Daniel M. Wilson, Jessica M. Heckman, Charles J. Kanegusuku, Helcio Pimentel Piemonte, Maria Elisa Mello, Marco Tulio de [UNIFESP] Forjaz, Claudia Roschel, Hamilton Tricoli, Valmor Ugrinowitsch, Carlos |
| dc.subject.por.fl_str_mv |
motor complexity exercise presynaptic inhibition disynaptic reciprocal inhibition descending drive proprioception |
| topic |
motor complexity exercise presynaptic inhibition disynaptic reciprocal inhibition descending drive proprioception |
| description |
This study assessed 1) the effects of 12 wk of resistance training (RT) and resistance training with instability (RTI) on presynaptic inhibition (PSI) and disynaptic reciprocal inhibition (DRI) of patients with Parkinson's disease (PD) |
| publishDate |
2017 |
| dc.date.none.fl_str_mv |
2017 2020-07-31T12:46:54Z 2020-07-31T12:46:54Z |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1152/japplphysiol.00557.2016 Journal Of Applied Physiology. Bethesda, v. 122, n. 1, p. 1-10, 2017. 10.1152/japplphysiol.00557.2016 8750-7587 https://repositorio.unifesp.br/handle/11600/56450 WOS:000393698000001 |
| url |
http://dx.doi.org/10.1152/japplphysiol.00557.2016 https://repositorio.unifesp.br/handle/11600/56450 |
| identifier_str_mv |
Journal Of Applied Physiology. Bethesda, v. 122, n. 1, p. 1-10, 2017. 10.1152/japplphysiol.00557.2016 8750-7587 WOS:000393698000001 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Journal Of Applied Physiology |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
1-10 |
| dc.coverage.none.fl_str_mv |
Bethesda |
| dc.publisher.none.fl_str_mv |
Amer Physiological Soc |
| publisher.none.fl_str_mv |
Amer Physiological Soc |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
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Universidade Federal de São Paulo (UNIFESP) |
| instacron_str |
UNIFESP |
| institution |
UNIFESP |
| reponame_str |
Repositório Institucional da UNIFESP |
| collection |
Repositório Institucional da UNIFESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
| repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
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1814268414829527040 |