Prediction of metabolic and cardiopulmonary responses to maximum cycle ergometry: a randomised study

• Autor(a) principal: Neder, Jose Alberto [UNIFESP]
• Data de Publicação: 1999
• Outros Autores: Nery, Luiz Eduardo [UNIFESP], Castelo Filho, Adauto [UNIFESP], Andreoni, Solange [UNIFESP], Lerario, Maria Cristina [UNIFESP], Sachs, Anita [UNIFESP], Silva, Antonio Carlos da [UNIFESP], Whipp, B. J.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1183/09031936.99.14613049; http://repositorio.unifesp.br/handle/11600/26183
• topic: cycle ergometry; exercise; oxygen consumption; reference values

All of the most widely-cited studies for the prediction of maximum exercise responses have utilized either volunteers or referred subjects. Therefore, selection bias, with overestimation of the reference values, is a likely consequence.In order to establish a set of predictive equations for the gas exchange, ventilatory and cardiovascular responses to maximum ramp-incremental cycle ergometry, this study prospectively evaluated 120 sedentary individuals (60 males, 60 females, aged 20-80), randomly-selected from >8,000 subjects. Regular physical activity pattern by questionnaire, body composition by anthropometry and dual energy X-ray absorptiometry (n=75) and knee strength by isokinetic dynamometry were also assessed.Previously reported equations typically overestimated the subjects' peak oxygen uptake (p<0.05). Prediction linear equations for the main variables of clinical interest were established by backward stepwise regression analysis including: sex, age, knee extensor peak torque, bone-free lean leg mass, total and lean body mass, height, and physical activity scares. Reference intervals (95% confidence limits) were calculated: some of these values differed markedly from those formerly recommended.The results therefore might provide a more appropriate frame of reference for interpretation of the responses to symptom-limited ramp incremental cycle ergometry in sedentary subjects; i.e. those usually referred tor clinical cardiopulmonary exercise tests.