The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host

Detalhes bibliográficos
Autor(a) principal: Puccia, Rosana [UNIFESP]
Data de Publicação: 2011
Outros Autores: Vallejo, Milene Carmes [UNIFESP], Matsuo, Alisson Leonardo [UNIFESP], Longo, Larissa Valle Guilhen [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.3389/fmicb.2011.00257
http://repositorio.unifesp.br/handle/11600/33234
Resumo: The cell wall of pathogenic fungi plays import roles in the interaction with the host, so that its composition and structure may determine the course of infection. Here we present an overview of the current and past knowledge on the cell wall constituents of Paracoccidioides brasiliensis and P. lutzii. These are temperature-dependent dimorphic fungi that cause paracoccidioidomycosis, a systemic granulomatous, and debilitating disease. Focus is given on cell wall carbohydrate and protein contents, their immune-stimulatory features, adhesion properties, drug target characteristics, and morphological phase specificity. We offer a journey toward the future understanding of the dynamic nature of the cell wall and of the changes that may occur when the fungus infects the human host.
id UFSP_3f4787d57e9f10229623cb018e5e40b1
oai_identifier_str oai:repositorio.unifesp.br/:11600/33234
network_acronym_str UFSP
network_name_str Repositório Institucional da UNIFESP
repository_id_str 3465
spelling The Paracoccidioides cell wall: past and present layers toward understanding interaction with the hostcell wallParacoccidioides brasiliensisP. lutziipolysaccharidesadhesinsenzymeshost interactionThe cell wall of pathogenic fungi plays import roles in the interaction with the host, so that its composition and structure may determine the course of infection. Here we present an overview of the current and past knowledge on the cell wall constituents of Paracoccidioides brasiliensis and P. lutzii. These are temperature-dependent dimorphic fungi that cause paracoccidioidomycosis, a systemic granulomatous, and debilitating disease. Focus is given on cell wall carbohydrate and protein contents, their immune-stimulatory features, adhesion properties, drug target characteristics, and morphological phase specificity. We offer a journey toward the future understanding of the dynamic nature of the cell wall and of the changes that may occur when the fungus infects the human host.Universidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, BrazilWeb of ScienceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Frontiers Research FoundationUniversidade Federal de São Paulo (UNIFESP)Puccia, Rosana [UNIFESP]Vallejo, Milene Carmes [UNIFESP]Matsuo, Alisson Leonardo [UNIFESP]Longo, Larissa Valle Guilhen [UNIFESP]2016-01-24T14:05:54Z2016-01-24T14:05:54Z2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion7application/pdfhttp://dx.doi.org/10.3389/fmicb.2011.00257Frontiers in Microbiology. Lausanne: Frontiers Research Foundation, v. 2, 7 p., 2011.10.3389/fmicb.2011.00257WOS000208863500265.pdf1664-302Xhttp://repositorio.unifesp.br/handle/11600/33234WOS:000208863500265engFrontiers in Microbiologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-31T13:47:46Zoai:repositorio.unifesp.br/:11600/33234Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-31T13:47:46Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host
title The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host
spellingShingle The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host
Puccia, Rosana [UNIFESP]
cell wall
Paracoccidioides brasiliensis
P. lutzii
polysaccharides
adhesins
enzymes
host interaction
title_short The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host
title_full The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host
title_fullStr The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host
title_full_unstemmed The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host
title_sort The Paracoccidioides cell wall: past and present layers toward understanding interaction with the host
author Puccia, Rosana [UNIFESP]
author_facet Puccia, Rosana [UNIFESP]
Vallejo, Milene Carmes [UNIFESP]
Matsuo, Alisson Leonardo [UNIFESP]
Longo, Larissa Valle Guilhen [UNIFESP]
author_role author
author2 Vallejo, Milene Carmes [UNIFESP]
Matsuo, Alisson Leonardo [UNIFESP]
Longo, Larissa Valle Guilhen [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Puccia, Rosana [UNIFESP]
Vallejo, Milene Carmes [UNIFESP]
Matsuo, Alisson Leonardo [UNIFESP]
Longo, Larissa Valle Guilhen [UNIFESP]
dc.subject.por.fl_str_mv cell wall
Paracoccidioides brasiliensis
P. lutzii
polysaccharides
adhesins
enzymes
host interaction
topic cell wall
Paracoccidioides brasiliensis
P. lutzii
polysaccharides
adhesins
enzymes
host interaction
description The cell wall of pathogenic fungi plays import roles in the interaction with the host, so that its composition and structure may determine the course of infection. Here we present an overview of the current and past knowledge on the cell wall constituents of Paracoccidioides brasiliensis and P. lutzii. These are temperature-dependent dimorphic fungi that cause paracoccidioidomycosis, a systemic granulomatous, and debilitating disease. Focus is given on cell wall carbohydrate and protein contents, their immune-stimulatory features, adhesion properties, drug target characteristics, and morphological phase specificity. We offer a journey toward the future understanding of the dynamic nature of the cell wall and of the changes that may occur when the fungus infects the human host.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
2016-01-24T14:05:54Z
2016-01-24T14:05:54Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3389/fmicb.2011.00257
Frontiers in Microbiology. Lausanne: Frontiers Research Foundation, v. 2, 7 p., 2011.
10.3389/fmicb.2011.00257
WOS000208863500265.pdf
1664-302X
http://repositorio.unifesp.br/handle/11600/33234
WOS:000208863500265
url http://dx.doi.org/10.3389/fmicb.2011.00257
http://repositorio.unifesp.br/handle/11600/33234
identifier_str_mv Frontiers in Microbiology. Lausanne: Frontiers Research Foundation, v. 2, 7 p., 2011.
10.3389/fmicb.2011.00257
WOS000208863500265.pdf
1664-302X
WOS:000208863500265
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Frontiers in Microbiology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7
application/pdf
dc.publisher.none.fl_str_mv Frontiers Research Foundation
publisher.none.fl_str_mv Frontiers Research Foundation
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268271950561280

Registros relacionados