Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S1413-86702008000600006 http://repositorio.unifesp.br/handle/11600/42881 |
Resumo: | The purpose of this study was to identify the rate of infections due to RSV and other viruses in children. In addition we have analyzed demographic data and clinical characteristics of the RSV-positive patients comparing with patients infected by other respiratory viruses. We also described the seasonality of the RSV occurrence in a hospital in Sao Paulo. Children below 5 years old admitted in Santa Casa de Sao Paulo Hospital between February 2005 and September 2006 due to acute respiratory infections (ARI) were included. A nasopharyngeal specimens were obtained with sterile No. 5 French feeding catheters as soon as possible (usually within 24 h). Specimens were kept refrigerated at 4 degrees C and transported to Adolfo Lutz Institute, where the indirect immunofluorescent assay was performed. Virus identified by these assay included RSV, Adenovirus, Influenza A and B virus and Parainfluenza 1, 2, and 3. Clinical data from each group was compared. Four hundred and fifty five cases were included in the study, with 30% positive for some type of virus. Viruses that were identified included Respiratory Syncytial Virus (73.03%), Influenza (8.42%), Parainfluenza (8.42%) and Adenovirus (3.37%). We divided the subjects in 3 groups: Group 1 RSV-Positive, Group 2 Other Positive Viruses and Group 3 Negative for Respiratory Virus. Mean age (months) was of 7.5 for RSV-positive children, 7.6 for other viruses, and 8 for negative for respiratory virus. The RSV-Positive Group was significantly younger than the Group Negative for Respiratory Virus (p<0.05). Signs of UAI were more present in the Positive RSV Group (p<0.05). General mortality was of 2.41%. There was a higher incidence of RSV between the months of March and August in the two years of the study. Our study indicates RSV as the most prevalent viral agent in children admitted due to (ARI), especially in infants below 3 months old. We have also found that infections due to RSV can occur in months others than the classic seasonal period. |
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Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo HospitalChildrenbronchiolitisRSVrespiratory infectionsThe purpose of this study was to identify the rate of infections due to RSV and other viruses in children. In addition we have analyzed demographic data and clinical characteristics of the RSV-positive patients comparing with patients infected by other respiratory viruses. We also described the seasonality of the RSV occurrence in a hospital in Sao Paulo. Children below 5 years old admitted in Santa Casa de Sao Paulo Hospital between February 2005 and September 2006 due to acute respiratory infections (ARI) were included. A nasopharyngeal specimens were obtained with sterile No. 5 French feeding catheters as soon as possible (usually within 24 h). Specimens were kept refrigerated at 4 degrees C and transported to Adolfo Lutz Institute, where the indirect immunofluorescent assay was performed. Virus identified by these assay included RSV, Adenovirus, Influenza A and B virus and Parainfluenza 1, 2, and 3. Clinical data from each group was compared. Four hundred and fifty five cases were included in the study, with 30% positive for some type of virus. Viruses that were identified included Respiratory Syncytial Virus (73.03%), Influenza (8.42%), Parainfluenza (8.42%) and Adenovirus (3.37%). We divided the subjects in 3 groups: Group 1 RSV-Positive, Group 2 Other Positive Viruses and Group 3 Negative for Respiratory Virus. Mean age (months) was of 7.5 for RSV-positive children, 7.6 for other viruses, and 8 for negative for respiratory virus. The RSV-Positive Group was significantly younger than the Group Negative for Respiratory Virus (p<0.05). Signs of UAI were more present in the Positive RSV Group (p<0.05). General mortality was of 2.41%. There was a higher incidence of RSV between the months of March and August in the two years of the study. Our study indicates RSV as the most prevalent viral agent in children admitted due to (ARI), especially in infants below 3 months old. We have also found that infections due to RSV can occur in months others than the classic seasonal period.Irmandade Santa Casa Misericordia Sao Paulo, Dept Pediat, Sao Paulo, BrazilSch Med Jundiai, Jundiai, SP, BrazilInst Adolfo Lutz Registro, Sao Paulo, BrazilUniv Sao Paulo, Inst Biomed Sci, Sao Paulo, BrazilWeb of ScienceContextoUniversidade Federal de São Paulo (UNIFESP)Sch Med JundiaiInst Adolfo Lutz RegistroUniversidade de São Paulo (USP)Pecchini, RogerioBerezin, Eitan Naaman [UNIFESP]Calahani Felicio, Maria C.Passos, Saulo D.Souza, Maria Candido O. deLima, Lourdes Rehder de Andrade Vaz deUeda, MirthesMatsumoto, Tokiko KyomenDurigon, Edison Luiz2018-06-15T14:04:34Z2018-06-15T14:04:34Z2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion476-479http://dx.doi.org/10.1590/S1413-86702008000600006Brazilian Journal Of Infectious Diseases. Salvador: Contexto, v. 12, n. 6, p. 476-479, 2008.10.1590/S1413-86702008000600006S1413-86702008000600006.pdf1413-8670S1413-86702008000600006http://repositorio.unifesp.br/handle/11600/42881WOS:000264200300006engBrazilian Journal Of Infectious Diseasesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-05-02T15:58:48Zoai:repositorio.unifesp.br/:11600/42881Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-05-02T15:58:48Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital |
title |
Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital |
spellingShingle |
Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital Pecchini, Rogerio Children bronchiolitis RSV respiratory infections |
title_short |
Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital |
title_full |
Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital |
title_fullStr |
Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital |
title_full_unstemmed |
Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital |
title_sort |
Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital |
author |
Pecchini, Rogerio |
author_facet |
Pecchini, Rogerio Berezin, Eitan Naaman [UNIFESP] Calahani Felicio, Maria C. Passos, Saulo D. Souza, Maria Candido O. de Lima, Lourdes Rehder de Andrade Vaz de Ueda, Mirthes Matsumoto, Tokiko Kyomen Durigon, Edison Luiz |
author_role |
author |
author2 |
Berezin, Eitan Naaman [UNIFESP] Calahani Felicio, Maria C. Passos, Saulo D. Souza, Maria Candido O. de Lima, Lourdes Rehder de Andrade Vaz de Ueda, Mirthes Matsumoto, Tokiko Kyomen Durigon, Edison Luiz |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Sch Med Jundiai Inst Adolfo Lutz Registro Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Pecchini, Rogerio Berezin, Eitan Naaman [UNIFESP] Calahani Felicio, Maria C. Passos, Saulo D. Souza, Maria Candido O. de Lima, Lourdes Rehder de Andrade Vaz de Ueda, Mirthes Matsumoto, Tokiko Kyomen Durigon, Edison Luiz |
dc.subject.por.fl_str_mv |
Children bronchiolitis RSV respiratory infections |
topic |
Children bronchiolitis RSV respiratory infections |
description |
The purpose of this study was to identify the rate of infections due to RSV and other viruses in children. In addition we have analyzed demographic data and clinical characteristics of the RSV-positive patients comparing with patients infected by other respiratory viruses. We also described the seasonality of the RSV occurrence in a hospital in Sao Paulo. Children below 5 years old admitted in Santa Casa de Sao Paulo Hospital between February 2005 and September 2006 due to acute respiratory infections (ARI) were included. A nasopharyngeal specimens were obtained with sterile No. 5 French feeding catheters as soon as possible (usually within 24 h). Specimens were kept refrigerated at 4 degrees C and transported to Adolfo Lutz Institute, where the indirect immunofluorescent assay was performed. Virus identified by these assay included RSV, Adenovirus, Influenza A and B virus and Parainfluenza 1, 2, and 3. Clinical data from each group was compared. Four hundred and fifty five cases were included in the study, with 30% positive for some type of virus. Viruses that were identified included Respiratory Syncytial Virus (73.03%), Influenza (8.42%), Parainfluenza (8.42%) and Adenovirus (3.37%). We divided the subjects in 3 groups: Group 1 RSV-Positive, Group 2 Other Positive Viruses and Group 3 Negative for Respiratory Virus. Mean age (months) was of 7.5 for RSV-positive children, 7.6 for other viruses, and 8 for negative for respiratory virus. The RSV-Positive Group was significantly younger than the Group Negative for Respiratory Virus (p<0.05). Signs of UAI were more present in the Positive RSV Group (p<0.05). General mortality was of 2.41%. There was a higher incidence of RSV between the months of March and August in the two years of the study. Our study indicates RSV as the most prevalent viral agent in children admitted due to (ARI), especially in infants below 3 months old. We have also found that infections due to RSV can occur in months others than the classic seasonal period. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-12-01 2018-06-15T14:04:34Z 2018-06-15T14:04:34Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1413-86702008000600006 Brazilian Journal Of Infectious Diseases. Salvador: Contexto, v. 12, n. 6, p. 476-479, 2008. 10.1590/S1413-86702008000600006 S1413-86702008000600006.pdf 1413-8670 S1413-86702008000600006 http://repositorio.unifesp.br/handle/11600/42881 WOS:000264200300006 |
url |
http://dx.doi.org/10.1590/S1413-86702008000600006 http://repositorio.unifesp.br/handle/11600/42881 |
identifier_str_mv |
Brazilian Journal Of Infectious Diseases. Salvador: Contexto, v. 12, n. 6, p. 476-479, 2008. 10.1590/S1413-86702008000600006 S1413-86702008000600006.pdf 1413-8670 S1413-86702008000600006 WOS:000264200300006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal Of Infectious Diseases |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
476-479 |
dc.publisher.none.fl_str_mv |
Contexto |
publisher.none.fl_str_mv |
Contexto |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
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1814268404170752000 |