Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital

Detalhes bibliográficos
Autor(a) principal: Pecchini, Rogerio
Data de Publicação: 2008
Outros Autores: Berezin, Eitan Naaman [UNIFESP], Calahani Felicio, Maria C., Passos, Saulo D., Souza, Maria Candido O. de, Lima, Lourdes Rehder de Andrade Vaz de, Ueda, Mirthes, Matsumoto, Tokiko Kyomen, Durigon, Edison Luiz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S1413-86702008000600006
http://repositorio.unifesp.br/handle/11600/42881
Resumo: The purpose of this study was to identify the rate of infections due to RSV and other viruses in children. In addition we have analyzed demographic data and clinical characteristics of the RSV-positive patients comparing with patients infected by other respiratory viruses. We also described the seasonality of the RSV occurrence in a hospital in Sao Paulo. Children below 5 years old admitted in Santa Casa de Sao Paulo Hospital between February 2005 and September 2006 due to acute respiratory infections (ARI) were included. A nasopharyngeal specimens were obtained with sterile No. 5 French feeding catheters as soon as possible (usually within 24 h). Specimens were kept refrigerated at 4 degrees C and transported to Adolfo Lutz Institute, where the indirect immunofluorescent assay was performed. Virus identified by these assay included RSV, Adenovirus, Influenza A and B virus and Parainfluenza 1, 2, and 3. Clinical data from each group was compared. Four hundred and fifty five cases were included in the study, with 30% positive for some type of virus. Viruses that were identified included Respiratory Syncytial Virus (73.03%), Influenza (8.42%), Parainfluenza (8.42%) and Adenovirus (3.37%). We divided the subjects in 3 groups: Group 1 RSV-Positive, Group 2 Other Positive Viruses and Group 3 Negative for Respiratory Virus. Mean age (months) was of 7.5 for RSV-positive children, 7.6 for other viruses, and 8 for negative for respiratory virus. The RSV-Positive Group was significantly younger than the Group Negative for Respiratory Virus (p<0.05). Signs of UAI were more present in the Positive RSV Group (p<0.05). General mortality was of 2.41%. There was a higher incidence of RSV between the months of March and August in the two years of the study. Our study indicates RSV as the most prevalent viral agent in children admitted due to (ARI), especially in infants below 3 months old. We have also found that infections due to RSV can occur in months others than the classic seasonal period.
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spelling Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo HospitalChildrenbronchiolitisRSVrespiratory infectionsThe purpose of this study was to identify the rate of infections due to RSV and other viruses in children. In addition we have analyzed demographic data and clinical characteristics of the RSV-positive patients comparing with patients infected by other respiratory viruses. We also described the seasonality of the RSV occurrence in a hospital in Sao Paulo. Children below 5 years old admitted in Santa Casa de Sao Paulo Hospital between February 2005 and September 2006 due to acute respiratory infections (ARI) were included. A nasopharyngeal specimens were obtained with sterile No. 5 French feeding catheters as soon as possible (usually within 24 h). Specimens were kept refrigerated at 4 degrees C and transported to Adolfo Lutz Institute, where the indirect immunofluorescent assay was performed. Virus identified by these assay included RSV, Adenovirus, Influenza A and B virus and Parainfluenza 1, 2, and 3. Clinical data from each group was compared. Four hundred and fifty five cases were included in the study, with 30% positive for some type of virus. Viruses that were identified included Respiratory Syncytial Virus (73.03%), Influenza (8.42%), Parainfluenza (8.42%) and Adenovirus (3.37%). We divided the subjects in 3 groups: Group 1 RSV-Positive, Group 2 Other Positive Viruses and Group 3 Negative for Respiratory Virus. Mean age (months) was of 7.5 for RSV-positive children, 7.6 for other viruses, and 8 for negative for respiratory virus. The RSV-Positive Group was significantly younger than the Group Negative for Respiratory Virus (p<0.05). Signs of UAI were more present in the Positive RSV Group (p<0.05). General mortality was of 2.41%. There was a higher incidence of RSV between the months of March and August in the two years of the study. Our study indicates RSV as the most prevalent viral agent in children admitted due to (ARI), especially in infants below 3 months old. We have also found that infections due to RSV can occur in months others than the classic seasonal period.Irmandade Santa Casa Misericordia Sao Paulo, Dept Pediat, Sao Paulo, BrazilSch Med Jundiai, Jundiai, SP, BrazilInst Adolfo Lutz Registro, Sao Paulo, BrazilUniv Sao Paulo, Inst Biomed Sci, Sao Paulo, BrazilWeb of ScienceContextoUniversidade Federal de São Paulo (UNIFESP)Sch Med JundiaiInst Adolfo Lutz RegistroUniversidade de São Paulo (USP)Pecchini, RogerioBerezin, Eitan Naaman [UNIFESP]Calahani Felicio, Maria C.Passos, Saulo D.Souza, Maria Candido O. deLima, Lourdes Rehder de Andrade Vaz deUeda, MirthesMatsumoto, Tokiko KyomenDurigon, Edison Luiz2018-06-15T14:04:34Z2018-06-15T14:04:34Z2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion476-479http://dx.doi.org/10.1590/S1413-86702008000600006Brazilian Journal Of Infectious Diseases. Salvador: Contexto, v. 12, n. 6, p. 476-479, 2008.10.1590/S1413-86702008000600006S1413-86702008000600006.pdf1413-8670S1413-86702008000600006http://repositorio.unifesp.br/handle/11600/42881WOS:000264200300006engBrazilian Journal Of Infectious Diseasesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-05-02T15:58:48Zoai:repositorio.unifesp.br/:11600/42881Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-05-02T15:58:48Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
title Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
spellingShingle Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
Pecchini, Rogerio
Children
bronchiolitis
RSV
respiratory infections
title_short Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
title_full Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
title_fullStr Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
title_full_unstemmed Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
title_sort Incidence and Clinical Characteristics of the Infection by the Respiratory Syncytial Virus in Children Admitted in Santa Casa de Sao Paulo Hospital
author Pecchini, Rogerio
author_facet Pecchini, Rogerio
Berezin, Eitan Naaman [UNIFESP]
Calahani Felicio, Maria C.
Passos, Saulo D.
Souza, Maria Candido O. de
Lima, Lourdes Rehder de Andrade Vaz de
Ueda, Mirthes
Matsumoto, Tokiko Kyomen
Durigon, Edison Luiz
author_role author
author2 Berezin, Eitan Naaman [UNIFESP]
Calahani Felicio, Maria C.
Passos, Saulo D.
Souza, Maria Candido O. de
Lima, Lourdes Rehder de Andrade Vaz de
Ueda, Mirthes
Matsumoto, Tokiko Kyomen
Durigon, Edison Luiz
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Sch Med Jundiai
Inst Adolfo Lutz Registro
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Pecchini, Rogerio
Berezin, Eitan Naaman [UNIFESP]
Calahani Felicio, Maria C.
Passos, Saulo D.
Souza, Maria Candido O. de
Lima, Lourdes Rehder de Andrade Vaz de
Ueda, Mirthes
Matsumoto, Tokiko Kyomen
Durigon, Edison Luiz
dc.subject.por.fl_str_mv Children
bronchiolitis
RSV
respiratory infections
topic Children
bronchiolitis
RSV
respiratory infections
description The purpose of this study was to identify the rate of infections due to RSV and other viruses in children. In addition we have analyzed demographic data and clinical characteristics of the RSV-positive patients comparing with patients infected by other respiratory viruses. We also described the seasonality of the RSV occurrence in a hospital in Sao Paulo. Children below 5 years old admitted in Santa Casa de Sao Paulo Hospital between February 2005 and September 2006 due to acute respiratory infections (ARI) were included. A nasopharyngeal specimens were obtained with sterile No. 5 French feeding catheters as soon as possible (usually within 24 h). Specimens were kept refrigerated at 4 degrees C and transported to Adolfo Lutz Institute, where the indirect immunofluorescent assay was performed. Virus identified by these assay included RSV, Adenovirus, Influenza A and B virus and Parainfluenza 1, 2, and 3. Clinical data from each group was compared. Four hundred and fifty five cases were included in the study, with 30% positive for some type of virus. Viruses that were identified included Respiratory Syncytial Virus (73.03%), Influenza (8.42%), Parainfluenza (8.42%) and Adenovirus (3.37%). We divided the subjects in 3 groups: Group 1 RSV-Positive, Group 2 Other Positive Viruses and Group 3 Negative for Respiratory Virus. Mean age (months) was of 7.5 for RSV-positive children, 7.6 for other viruses, and 8 for negative for respiratory virus. The RSV-Positive Group was significantly younger than the Group Negative for Respiratory Virus (p<0.05). Signs of UAI were more present in the Positive RSV Group (p<0.05). General mortality was of 2.41%. There was a higher incidence of RSV between the months of March and August in the two years of the study. Our study indicates RSV as the most prevalent viral agent in children admitted due to (ARI), especially in infants below 3 months old. We have also found that infections due to RSV can occur in months others than the classic seasonal period.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-01
2018-06-15T14:04:34Z
2018-06-15T14:04:34Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1413-86702008000600006
Brazilian Journal Of Infectious Diseases. Salvador: Contexto, v. 12, n. 6, p. 476-479, 2008.
10.1590/S1413-86702008000600006
S1413-86702008000600006.pdf
1413-8670
S1413-86702008000600006
http://repositorio.unifesp.br/handle/11600/42881
WOS:000264200300006
url http://dx.doi.org/10.1590/S1413-86702008000600006
http://repositorio.unifesp.br/handle/11600/42881
identifier_str_mv Brazilian Journal Of Infectious Diseases. Salvador: Contexto, v. 12, n. 6, p. 476-479, 2008.
10.1590/S1413-86702008000600006
S1413-86702008000600006.pdf
1413-8670
S1413-86702008000600006
WOS:000264200300006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal Of Infectious Diseases
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 476-479
dc.publisher.none.fl_str_mv Contexto
publisher.none.fl_str_mv Contexto
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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