Alterações ultra-sonográficas na gravidez Rh negativo sensibilizada avaliada pela espectrofotometria do líquido amniótico e pela dopplervelocimetria da artéria cerebral média

• Autor(a) principal: Nardozza, Luciano Marcondes Machado [UNIFESP]
• Data de Publicação: 2006
• Outros Autores: Camano, Luiz [UNIFESP], Moron, Antonio Fernandes [UNIFESP], Pares, David Baptista da Silva [UNIFESP], Chinen, Paulo Alexandre [UNIFESP], Lobo, Guilherme Antonio Rago
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0100-39842006000100004; http://repositorio.unifesp.br/handle/11600/2911
• topic: Red blood cell isoimmunization; Fetal anemia; Middle cerebral artery; Doppler ultrasonography; Isoantibodies; Fetal erythroblastosis; Isoimunização; Anemia fetal; Artéria cerebral média; Ultra-som Doppler; Aloanticorpos; Eritroblastose fetal

OBJECTIVE: To evaluate and compare existing ultrasound findings in women with Rh-alloimmunized pregnancies with diagnosis of fetal anemia by spectrophotometric analysis of amniotic fluid or Doppler ultrasound of the fetal middle cerebral artery. MATERIALS AND METHODS: This was an observational descriptive study involving 99 patients evaluated between January 1995 and January 2004. Patients were divided into two groups: 74 Rh-isoimmunized women submitted to spectrophotometry of the amniotic fluid (group S) and 25 Rh-isoimmunized women submitted to Doppler ultrasound of fetal middle cerebral artery (group D) to evaluate fetal anemia. Ultrasound findings in the two groups were compared. RESULTS: Placental anomalies, mainly placentomegaly and textural irregularities were more frequently seen in pregnant women followed up with spectrophotometry of the amniotic fluid compared to those followed up with Doppler ultrasound (64% X 32%, p = 6,294). CONCLUSION: The frequency of abnormal ultrasound findings was 2-fold higher in pregnancies evaluated with spectrophotometry of the amniotic fluid compared to those followed up with Doppler ultrasound.