First Description of KPC-2-Producing Klebsiella oxytoca in Brazil

Detalhes bibliográficos
Autor(a) principal: Almeida, Anna C. S.
Data de Publicação: 2013
Outros Autores: Cavalcanti, Felipe L. S., Martins, Willames M. B., Vilela, Marinalda A., Gales, Ana C. [UNIFESP], Morais Junior, Marcos A., Morais, Marcia M. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://repositorio.unifesp.br/handle/11600/36563
http://dx.doi.org/10.1128/AAC.02376-12
Resumo: The present work reports the detection of the first case of nosocomial Klebsiella oxytoca producing class A carbapenemase KPC-2 in Brazil. the isolate KPN106 carried a 65-kb IncW-type plasmid that harbors the bla(KPC) gene and Tn4401b. Moreover, we detected the presence of a class 1 integron containing a new allele, arr-8, followed by a 5'-truncated dhfrIIIc gene. in view of the recent results, we emphasize the high variability of the bacterial and genetic hosts of this resistance determinant.
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spelling Almeida, Anna C. S.Cavalcanti, Felipe L. S.Martins, Willames M. B.Vilela, Marinalda A.Gales, Ana C. [UNIFESP]Morais Junior, Marcos A.Morais, Marcia M. C.Univ PernambucoUniversidade Federal de Pernambuco (UFPE)Universidade Federal de São Paulo (UNIFESP)CPqAM Fiocruz2016-01-24T14:32:01Z2016-01-24T14:32:01Z2013-08-01Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 57, n. 8, p. 4077-4078, 2013.0066-4804http://repositorio.unifesp.br/handle/11600/36563http://dx.doi.org/10.1128/AAC.02376-12WOS000321761800086.pdf10.1128/AAC.02376-12WOS:000321761800086The present work reports the detection of the first case of nosocomial Klebsiella oxytoca producing class A carbapenemase KPC-2 in Brazil. the isolate KPN106 carried a 65-kb IncW-type plasmid that harbors the bla(KPC) gene and Tn4401b. Moreover, we detected the presence of a class 1 integron containing a new allele, arr-8, followed by a 5'-truncated dhfrIIIc gene. in view of the recent results, we emphasize the high variability of the bacterial and genetic hosts of this resistance determinant.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)FACEPEPFA/UPEUniv Pernambuco, Inst Ciencias Biol, Lab Resistencia Microbiana, Recife, PE, BrazilUniv Fed Pernambuco, Dept Genet, Lab Genet Microrganismos, Recife, PE, BrazilUniversidade Federal de São Paulo, Lab Alerta, São Paulo, BrazilCPqAM Fiocruz, Ctr Pesquisa Aggeu Magalhaes, Recife, PE, BrazilUniversidade Federal de São Paulo, Lab Alerta, São Paulo, BrazilWeb of Science4077-4078engAmer Soc MicrobiologyAntimicrobial Agents and ChemotherapyFirst Description of KPC-2-Producing Klebsiella oxytoca in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000321761800086.pdfapplication/pdf94549${dspace.ui.url}/bitstream/11600/36563/1/WOS000321761800086.pdf5efe72bb3f24f3f1052ccba491b27f9cMD51open accessTEXTWOS000321761800086.pdf.txtWOS000321761800086.pdf.txtExtracted texttext/plain7742${dspace.ui.url}/bitstream/11600/36563/2/WOS000321761800086.pdf.txt6338a61e8e052f6e520ab9f793a40d03MD52open access11600/365632022-02-18 12:08:04.393open accessoai:repositorio.unifesp.br:11600/36563Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652022-02-18T15:08:04Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.en.fl_str_mv First Description of KPC-2-Producing Klebsiella oxytoca in Brazil
title First Description of KPC-2-Producing Klebsiella oxytoca in Brazil
spellingShingle First Description of KPC-2-Producing Klebsiella oxytoca in Brazil
Almeida, Anna C. S.
title_short First Description of KPC-2-Producing Klebsiella oxytoca in Brazil
title_full First Description of KPC-2-Producing Klebsiella oxytoca in Brazil
title_fullStr First Description of KPC-2-Producing Klebsiella oxytoca in Brazil
title_full_unstemmed First Description of KPC-2-Producing Klebsiella oxytoca in Brazil
title_sort First Description of KPC-2-Producing Klebsiella oxytoca in Brazil
author Almeida, Anna C. S.
author_facet Almeida, Anna C. S.
Cavalcanti, Felipe L. S.
Martins, Willames M. B.
Vilela, Marinalda A.
Gales, Ana C. [UNIFESP]
Morais Junior, Marcos A.
Morais, Marcia M. C.
author_role author
author2 Cavalcanti, Felipe L. S.
Martins, Willames M. B.
Vilela, Marinalda A.
Gales, Ana C. [UNIFESP]
Morais Junior, Marcos A.
Morais, Marcia M. C.
author2_role author
author
author
author
author
author
dc.contributor.institution.none.fl_str_mv Univ Pernambuco
Universidade Federal de Pernambuco (UFPE)
Universidade Federal de São Paulo (UNIFESP)
CPqAM Fiocruz
dc.contributor.author.fl_str_mv Almeida, Anna C. S.
Cavalcanti, Felipe L. S.
Martins, Willames M. B.
Vilela, Marinalda A.
Gales, Ana C. [UNIFESP]
Morais Junior, Marcos A.
Morais, Marcia M. C.
description The present work reports the detection of the first case of nosocomial Klebsiella oxytoca producing class A carbapenemase KPC-2 in Brazil. the isolate KPN106 carried a 65-kb IncW-type plasmid that harbors the bla(KPC) gene and Tn4401b. Moreover, we detected the presence of a class 1 integron containing a new allele, arr-8, followed by a 5'-truncated dhfrIIIc gene. in view of the recent results, we emphasize the high variability of the bacterial and genetic hosts of this resistance determinant.
publishDate 2013
dc.date.issued.fl_str_mv 2013-08-01
dc.date.accessioned.fl_str_mv 2016-01-24T14:32:01Z
dc.date.available.fl_str_mv 2016-01-24T14:32:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 57, n. 8, p. 4077-4078, 2013.
dc.identifier.uri.fl_str_mv http://repositorio.unifesp.br/handle/11600/36563
http://dx.doi.org/10.1128/AAC.02376-12
dc.identifier.issn.none.fl_str_mv 0066-4804
dc.identifier.file.none.fl_str_mv WOS000321761800086.pdf
dc.identifier.doi.none.fl_str_mv 10.1128/AAC.02376-12
dc.identifier.wos.none.fl_str_mv WOS:000321761800086
identifier_str_mv Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 57, n. 8, p. 4077-4078, 2013.
0066-4804
WOS000321761800086.pdf
10.1128/AAC.02376-12
WOS:000321761800086
url http://repositorio.unifesp.br/handle/11600/36563
http://dx.doi.org/10.1128/AAC.02376-12
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Antimicrobial Agents and Chemotherapy
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 4077-4078
dc.publisher.none.fl_str_mv Amer Soc Microbiology
publisher.none.fl_str_mv Amer Soc Microbiology
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
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