Cytotoxic T cells and mycobacteria

Detalhes bibliográficos
Autor(a) principal: Silva, Celio L.
Data de Publicação: 2001
Outros Autores: Bonato, Vania LD, Lima, Karla M., Coelho-Castelo, Arlete AM, Faccioli, Lucia H., Sartori, Alexandrina, De Souza, Ana O., Leao, Sylvia Cardoso [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1111/j.1574-6968.2001.tb10575.x
http://repositorio.unifesp.br/handle/11600/26512
Resumo: How the immune system kills Mycobacterium tuberculosis is still a puzzle. the classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
id UFSP_47d8c7e9a96ad3b7d702061a2876bfd8
oai_identifier_str oai:repositorio.unifesp.br/:11600/26512
network_acronym_str UFSP
network_name_str Repositório Institucional da UNIFESP
repository_id_str 3465
spelling Cytotoxic T cells and mycobacteriacytotoxic T lymphocytemacrophage activationcellular immune responseDNA vaccinegene therapyMycobacterium tuberculosisHow the immune system kills Mycobacterium tuberculosis is still a puzzle. the classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.Univ São Paulo, Sch Med Ribeirao Preto, Dept Biochem & Immunol, BR-14049900 Ribeirao Preto, SP, BrazilUniv São Paulo, Sch Pharmaceut Sci Ribeirao Preto, Dept Clin Anal Bromatol & Toxicol, BR-14049 Ribeirao Preto, SP, BrazilUniversidade Federal de São Paulo, Dept Microbiol & Immunol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Microbiol & Immunol, São Paulo, BrazilWeb of ScienceElsevier B.V.Universidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)Silva, Celio L.Bonato, Vania LDLima, Karla M.Coelho-Castelo, Arlete AMFaccioli, Lucia H.Sartori, AlexandrinaDe Souza, Ana O.Leao, Sylvia Cardoso [UNIFESP]2016-01-24T12:31:20Z2016-01-24T12:31:20Z2001-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion11-18http://dx.doi.org/10.1111/j.1574-6968.2001.tb10575.xFems Microbiology Letters. Amsterdam: Elsevier B.V., v. 197, n. 1, p. 11-18, 2001.10.1111/j.1574-6968.2001.tb10575.x0378-1097http://repositorio.unifesp.br/handle/11600/26512WOS:000167980100002engFems Microbiology Lettersinfo:eu-repo/semantics/openAccesshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2023-03-27T13:59:24Zoai:repositorio.unifesp.br/:11600/26512Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652023-03-27T13:59:24Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Cytotoxic T cells and mycobacteria
title Cytotoxic T cells and mycobacteria
spellingShingle Cytotoxic T cells and mycobacteria
Silva, Celio L.
cytotoxic T lymphocyte
macrophage activation
cellular immune response
DNA vaccine
gene therapy
Mycobacterium tuberculosis
title_short Cytotoxic T cells and mycobacteria
title_full Cytotoxic T cells and mycobacteria
title_fullStr Cytotoxic T cells and mycobacteria
title_full_unstemmed Cytotoxic T cells and mycobacteria
title_sort Cytotoxic T cells and mycobacteria
author Silva, Celio L.
author_facet Silva, Celio L.
Bonato, Vania LD
Lima, Karla M.
Coelho-Castelo, Arlete AM
Faccioli, Lucia H.
Sartori, Alexandrina
De Souza, Ana O.
Leao, Sylvia Cardoso [UNIFESP]
author_role author
author2 Bonato, Vania LD
Lima, Karla M.
Coelho-Castelo, Arlete AM
Faccioli, Lucia H.
Sartori, Alexandrina
De Souza, Ana O.
Leao, Sylvia Cardoso [UNIFESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Silva, Celio L.
Bonato, Vania LD
Lima, Karla M.
Coelho-Castelo, Arlete AM
Faccioli, Lucia H.
Sartori, Alexandrina
De Souza, Ana O.
Leao, Sylvia Cardoso [UNIFESP]
dc.subject.por.fl_str_mv cytotoxic T lymphocyte
macrophage activation
cellular immune response
DNA vaccine
gene therapy
Mycobacterium tuberculosis
topic cytotoxic T lymphocyte
macrophage activation
cellular immune response
DNA vaccine
gene therapy
Mycobacterium tuberculosis
description How the immune system kills Mycobacterium tuberculosis is still a puzzle. the classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
publishDate 2001
dc.date.none.fl_str_mv 2001-04-01
2016-01-24T12:31:20Z
2016-01-24T12:31:20Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1111/j.1574-6968.2001.tb10575.x
Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 197, n. 1, p. 11-18, 2001.
10.1111/j.1574-6968.2001.tb10575.x
0378-1097
http://repositorio.unifesp.br/handle/11600/26512
WOS:000167980100002
url http://dx.doi.org/10.1111/j.1574-6968.2001.tb10575.x
http://repositorio.unifesp.br/handle/11600/26512
identifier_str_mv Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 197, n. 1, p. 11-18, 2001.
10.1111/j.1574-6968.2001.tb10575.x
0378-1097
WOS:000167980100002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Fems Microbiology Letters
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
eu_rights_str_mv openAccess
rights_invalid_str_mv http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.format.none.fl_str_mv 11-18
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268417293680640

Registros relacionados