Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer

Detalhes bibliográficos
Autor(a) principal: Garófolo, Adriana [UNIFESP]
Data de Publicação: 2010
Outros Autores: Maia-Lemos, Priscila dos Santos [UNIFESP], Petrilli, Antonio Sergio [UNIFESP], Ancona-Lopez, Fábio [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: https://dx.doi.org/10.1590/S1415-52732010000500003
https://repositorio.unifesp.br/handle/11600/5965
Resumo: Objective This study aimed to describe the algorithm and the global results after its implementation. Methods This was a randomized clinical trial done with malnourished cancer patients. Follow-up followed an algorithm and patients with mild malnutrition were randomized to receive store-bought or homemade oral supplementation. The patients were reassessed after three, eight and twelve weeks. Depending on how the group supplemented with store-bought supplements responded, the supplementation was either continued orally, by tube-feeding or discontinued. The group receiving homemade supplementation either continued on it if the response was positive or received store-bought oral supplementation if the response was negative. The severely malnourished patients either received store-bought supplementation by feeding tube or orally, or it was discontinued if an adequate nutritional status was reached. The patients' responses to supplementation were determined by weight-for-height Z-scores, body mass indices, triceps skinfold thicknesses and circumferences. Results One hundred and seventeen out of 141 patients completed the first three weeks; 58 were severely malnourished and 59 were mildly malnourished. The nutritional status of 41% of the severely malnourished patients and 97% of the mildly malnourished patients receiving store-bought supplement orally improved. The nutritional status of 77% of the mildly malnourished patients receiving homemade supplement orally also improved. Of the 117 patients, 42 had to be tube-fed; of these, 23 accepted and 19 refused tube feeding and continued taking store-bought supplement orally. Consumption of store-bought supplement was higher in tube-fed patients than in orally-fed patients. Consumption also increased as orally-fed patients became tube-fed. Store-bought supplements given by tube improved nutritional status, showing a positive association between duration of tube feeding and nutritional status. Conclusion Store-bought oral supplements improved the nutrient intake of malnourished patients, especially those who were mildly malnourished. The results also suggest that store-bought supplements given by tube improve nutritional status, especially as duration of tube feeding increases.
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spelling Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncerOutcomes of the implementation of an enteral nutrition algorithm in children and adolescents with cancerAlgorithmNeoplasmsEnteral nutritionNutritional supportAlgoritmoNeoplasiasNutrição enteralTerapia nutricionalObjective This study aimed to describe the algorithm and the global results after its implementation. Methods This was a randomized clinical trial done with malnourished cancer patients. Follow-up followed an algorithm and patients with mild malnutrition were randomized to receive store-bought or homemade oral supplementation. The patients were reassessed after three, eight and twelve weeks. Depending on how the group supplemented with store-bought supplements responded, the supplementation was either continued orally, by tube-feeding or discontinued. The group receiving homemade supplementation either continued on it if the response was positive or received store-bought oral supplementation if the response was negative. The severely malnourished patients either received store-bought supplementation by feeding tube or orally, or it was discontinued if an adequate nutritional status was reached. The patients' responses to supplementation were determined by weight-for-height Z-scores, body mass indices, triceps skinfold thicknesses and circumferences. Results One hundred and seventeen out of 141 patients completed the first three weeks; 58 were severely malnourished and 59 were mildly malnourished. The nutritional status of 41% of the severely malnourished patients and 97% of the mildly malnourished patients receiving store-bought supplement orally improved. The nutritional status of 77% of the mildly malnourished patients receiving homemade supplement orally also improved. Of the 117 patients, 42 had to be tube-fed; of these, 23 accepted and 19 refused tube feeding and continued taking store-bought supplement orally. Consumption of store-bought supplement was higher in tube-fed patients than in orally-fed patients. Consumption also increased as orally-fed patients became tube-fed. Store-bought supplements given by tube improved nutritional status, showing a positive association between duration of tube feeding and nutritional status. Conclusion Store-bought oral supplements improved the nutrient intake of malnourished patients, especially those who were mildly malnourished. The results also suggest that store-bought supplements given by tube improve nutritional status, especially as duration of tube feeding increases.Objetivo Descrever o algoritmo e os resultados globais após sua implantação. Métodos Ensaio clínico randomizado realizado com pacientes com câncer e desnutrição. O acompanhamento foi guiado por algoritmo, e desnutridos leves eram randomizados para suplementação oral industrializada ou artesanal, reavaliados após três, oito e doze semanas. Dependendo da resposta no grupo suplementação oral indus-trializada, indicava-se suplemento industrializado por sonda, mantinha-se suplementação oral industrializada ou ela era suspensa. O grupo suplementação oral artesanal com resposta positiva permaneceu com a mesma orientação; se negativa iniciou com suplementação oral industrializada. Nos desnutridos graves, resposta negativa indicou suplemento industrializado por sonda, positiva manteve suplementação oral industrializada ou ela era suspensa no caso de eutrofia. A avaliação das respostas foi realizada por meio do escore-Z de peso para estatura, índice de massa corpórea, prega cutânea triciptal e circunferências. Resultados Cento e dezessete de 141 pacientes completaram três semanas iniciais; 58 desnutridos grave e 59 leve. Evolução nutricional positiva ocorreu em 41% dos graves, em 97% dos leves com suplementação oral industrializada e em 77% dos desnutridos leves com suplementação oral artesanal. Dos 117, 42 tiveram indicação de suplemento industrializado por sonda; 23 usaram e 19 recusaram, mantendo suplementação oral industrializada. Pacientes que usaram suplemento industrializado por sonda apresentaram consumo de suplemento superior aos demais; o consumo de suplemento industrializado por sonda também foi superior quando comparado ao período anterior com suplementação oral industrializada nos mesmos pacientes. O uso de suplemento industrializado por sonda demonstrou melhorar o estado nutricional, com associação positiva entre sua duração e evolução nutricional. Conclusão Suplementação oral industrializada reduziu o deficit nutricional, principalmente em desnutridos leves. Os resultados sugerem que a suplemento industrializado por sonda favoreceu a recuperação nutricional, principalmente com o uso mais prolongado.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Instituto de Oncologia PediátricaUNIFESP, EPM, Instituto de Oncologia PediátricaSciELOPontifícia Universidade Católica de CampinasUniversidade Federal de São Paulo (UNIFESP)Garófolo, Adriana [UNIFESP]Maia-Lemos, Priscila dos Santos [UNIFESP]Petrilli, Antonio Sergio [UNIFESP]Ancona-Lopez, Fábio [UNIFESP]2015-06-14T13:41:54Z2015-06-14T13:41:54Z2010-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion715-730application/pdfhttps://dx.doi.org/10.1590/S1415-52732010000500003GAROFOLO, Adriana; MAIA, Priscila Santos; PETRILLI, Antonio Sérgio e ANCONA-LOPEZ, Fábio. Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer. Rev. Nutr. [online]. 2010, vol.23, n.5, pp.715-73010.1590/S1415-52732010000500003S1415-52732010000500003.pdf1415-5273S1415-52732010000500003https://repositorio.unifesp.br/handle/11600/5965WOS:000288382400003porRevista de Nutriçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-27T17:56:43Zoai:repositorio.unifesp.br/:11600/5965Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-27T17:56:43Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer
Outcomes of the implementation of an enteral nutrition algorithm in children and adolescents with cancer
title Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer
spellingShingle Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer
Garófolo, Adriana [UNIFESP]
Algorithm
Neoplasms
Enteral nutrition
Nutritional support
Algoritmo
Neoplasias
Nutrição enteral
Terapia nutricional
title_short Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer
title_full Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer
title_fullStr Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer
title_full_unstemmed Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer
title_sort Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer
author Garófolo, Adriana [UNIFESP]
author_facet Garófolo, Adriana [UNIFESP]
Maia-Lemos, Priscila dos Santos [UNIFESP]
Petrilli, Antonio Sergio [UNIFESP]
Ancona-Lopez, Fábio [UNIFESP]
author_role author
author2 Maia-Lemos, Priscila dos Santos [UNIFESP]
Petrilli, Antonio Sergio [UNIFESP]
Ancona-Lopez, Fábio [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Garófolo, Adriana [UNIFESP]
Maia-Lemos, Priscila dos Santos [UNIFESP]
Petrilli, Antonio Sergio [UNIFESP]
Ancona-Lopez, Fábio [UNIFESP]
dc.subject.por.fl_str_mv Algorithm
Neoplasms
Enteral nutrition
Nutritional support
Algoritmo
Neoplasias
Nutrição enteral
Terapia nutricional
topic Algorithm
Neoplasms
Enteral nutrition
Nutritional support
Algoritmo
Neoplasias
Nutrição enteral
Terapia nutricional
description Objective This study aimed to describe the algorithm and the global results after its implementation. Methods This was a randomized clinical trial done with malnourished cancer patients. Follow-up followed an algorithm and patients with mild malnutrition were randomized to receive store-bought or homemade oral supplementation. The patients were reassessed after three, eight and twelve weeks. Depending on how the group supplemented with store-bought supplements responded, the supplementation was either continued orally, by tube-feeding or discontinued. The group receiving homemade supplementation either continued on it if the response was positive or received store-bought oral supplementation if the response was negative. The severely malnourished patients either received store-bought supplementation by feeding tube or orally, or it was discontinued if an adequate nutritional status was reached. The patients' responses to supplementation were determined by weight-for-height Z-scores, body mass indices, triceps skinfold thicknesses and circumferences. Results One hundred and seventeen out of 141 patients completed the first three weeks; 58 were severely malnourished and 59 were mildly malnourished. The nutritional status of 41% of the severely malnourished patients and 97% of the mildly malnourished patients receiving store-bought supplement orally improved. The nutritional status of 77% of the mildly malnourished patients receiving homemade supplement orally also improved. Of the 117 patients, 42 had to be tube-fed; of these, 23 accepted and 19 refused tube feeding and continued taking store-bought supplement orally. Consumption of store-bought supplement was higher in tube-fed patients than in orally-fed patients. Consumption also increased as orally-fed patients became tube-fed. Store-bought supplements given by tube improved nutritional status, showing a positive association between duration of tube feeding and nutritional status. Conclusion Store-bought oral supplements improved the nutrient intake of malnourished patients, especially those who were mildly malnourished. The results also suggest that store-bought supplements given by tube improve nutritional status, especially as duration of tube feeding increases.
publishDate 2010
dc.date.none.fl_str_mv 2010-10-01
2015-06-14T13:41:54Z
2015-06-14T13:41:54Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://dx.doi.org/10.1590/S1415-52732010000500003
GAROFOLO, Adriana; MAIA, Priscila Santos; PETRILLI, Antonio Sérgio e ANCONA-LOPEZ, Fábio. Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer. Rev. Nutr. [online]. 2010, vol.23, n.5, pp.715-730
10.1590/S1415-52732010000500003
S1415-52732010000500003.pdf
1415-5273
S1415-52732010000500003
https://repositorio.unifesp.br/handle/11600/5965
WOS:000288382400003
url https://dx.doi.org/10.1590/S1415-52732010000500003
https://repositorio.unifesp.br/handle/11600/5965
identifier_str_mv GAROFOLO, Adriana; MAIA, Priscila Santos; PETRILLI, Antonio Sérgio e ANCONA-LOPEZ, Fábio. Resultados da implantação de um algoritmo para terapia nutricional enteral em crianças e adolescentes com câncer. Rev. Nutr. [online]. 2010, vol.23, n.5, pp.715-730
10.1590/S1415-52732010000500003
S1415-52732010000500003.pdf
1415-5273
S1415-52732010000500003
WOS:000288382400003
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista de Nutrição
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 715-730
application/pdf
dc.publisher.none.fl_str_mv Pontifícia Universidade Católica de Campinas
publisher.none.fl_str_mv Pontifícia Universidade Católica de Campinas
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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