What do Cochrane systematic reviews say about interventions for autism spectrum disorders?

Detalhes bibliográficos
Autor(a) principal: Lyra, Larissa [UNIFESP]
Data de Publicação: 2017
Outros Autores: Rizzo, Luiz Eduardo [UNIFESP], Sunahara, Camila Sa [UNIFESP], Pachito, Daniela Vianna [UNIFESP], Cruz Latorraca, Carolina de Oliveira [UNIFESP], Cabrera Martimbianco, Ana Luiza, Riera, Rachel [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/1516-3180.2017.0058200317
https://repositorio.unifesp.br/handle/11600/54964
Resumo: CONTEXT AND OBJECTIVE: Autism spectrum disorders (ASDs) include autistic disorder, Asperger's disorder and pervasive developmental disorder. The manifestations of ASDs can have an important impact on learning and social functioning that may persist during adulthood. The aim here was to summarize the evidence from Cochrane systematic reviews on interventions for ASDs. DESIGN AND SETTING: Review of systematic reviews, conducted within the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo. METHODS: We included and summarized the results from Cochrane systematic reviews on interventions for ASDs. RESULTS: Seventeen reviews were included. These found weak evidence of benefits from acupuncture, gluten and casein-free diets, early intensive behavioral interventions, music therapy, parent-mediated early interventions, social skill groups, Theory of Mind cognitive model, aripiprazole, risperidone, tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRI)
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spelling What do Cochrane systematic reviews say about interventions for autism spectrum disorders?Autism spectrum disorderTherapeuticsReview [Publication type]Evidence-based practiceEvidence-based medicineCONTEXT AND OBJECTIVE: Autism spectrum disorders (ASDs) include autistic disorder, Asperger's disorder and pervasive developmental disorder. The manifestations of ASDs can have an important impact on learning and social functioning that may persist during adulthood. The aim here was to summarize the evidence from Cochrane systematic reviews on interventions for ASDs. DESIGN AND SETTING: Review of systematic reviews, conducted within the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo. METHODS: We included and summarized the results from Cochrane systematic reviews on interventions for ASDs. RESULTS: Seventeen reviews were included. These found weak evidence of benefits from acupuncture, gluten and casein-free diets, early intensive behavioral interventions, music therapy, parent-mediated early interventions, social skill groups, Theory of Mind cognitive model, aripiprazole, risperidone, tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRI)this last only for adults. No benefits were found for sound therapies, chelating agents, hyperbaric oxygen therapy, omega-3, secretin, vitamin B6/magnesium and SSRI for children. CONCLUSION: Acupuncture, gluten and casein-free diets, early intensive behavioral interventions, music therapy, parent-mediated early interventions, social skill groups and the Theory of Mind cognitive model seem to have benefits for patients with autism spectrum disorders (very low to low-quality evidence). Aripiprazole, risperidone, tricyclic antidepressants and SSRI (this last only for adults) also showed some benefits, although associated with higher risk of adverse events. Experimental studies to confirm a link between probable therapies and the disease, and then high-quality long-term clinical trials, are needed.Univ Fed Sao Paulo Unifesp, EPM, Discipline Evidence Based Med, Sao Paulo, SP, BrazilUniv Fed Sao Paulo Unifesp, EPM, Sao Paulo, SP, BrazilUniv Fed Sao Paulo Unifesp, Evidence Based Hlth Program, Sao Paulo, SP, BrazilCochrane Brazil, Sao Paulo, SP, BrazilUniv Fed Sao Paulo Unifesp, EPM, Discipline Evidence Based Med, Sao Paulo, SP, BrazilUniv Fed Sao Paulo Unifesp, EPM, Sao Paulo, SP, BrazilUniv Fed Sao Paulo Unifesp, Evidence Based Hlth Program, Sao Paulo, SP, BrazilWeb of ScienceAssociacao Paulista Medicina2020-07-17T14:02:43Z2020-07-17T14:02:43Z2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion192-201application/pdfhttp://dx.doi.org/10.1590/1516-3180.2017.0058200317Sao Paulo Medical Journal. Sao Paulo, v. 135, n. 2, p. 192-201, 2017.10.1590/1516-3180.2017.0058200317WOS000402009700017.pdf1516-3180https://repositorio.unifesp.br/handle/11600/54964WOS:000402009700017engSao Paulo Medical JournalSao Pauloinfo:eu-repo/semantics/openAccessLyra, Larissa [UNIFESP]Rizzo, Luiz Eduardo [UNIFESP]Sunahara, Camila Sa [UNIFESP]Pachito, Daniela Vianna [UNIFESP]Cruz Latorraca, Carolina de Oliveira [UNIFESP]Cabrera Martimbianco, Ana LuizaRiera, Rachel [UNIFESP]reponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-02T10:42:43Zoai:repositorio.unifesp.br/:11600/54964Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-02T10:42:43Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv What do Cochrane systematic reviews say about interventions for autism spectrum disorders?
title What do Cochrane systematic reviews say about interventions for autism spectrum disorders?
spellingShingle What do Cochrane systematic reviews say about interventions for autism spectrum disorders?
Lyra, Larissa [UNIFESP]
Autism spectrum disorder
Therapeutics
Review [Publication type]
Evidence-based practice
Evidence-based medicine
title_short What do Cochrane systematic reviews say about interventions for autism spectrum disorders?
title_full What do Cochrane systematic reviews say about interventions for autism spectrum disorders?
title_fullStr What do Cochrane systematic reviews say about interventions for autism spectrum disorders?
title_full_unstemmed What do Cochrane systematic reviews say about interventions for autism spectrum disorders?
title_sort What do Cochrane systematic reviews say about interventions for autism spectrum disorders?
author Lyra, Larissa [UNIFESP]
author_facet Lyra, Larissa [UNIFESP]
Rizzo, Luiz Eduardo [UNIFESP]
Sunahara, Camila Sa [UNIFESP]
Pachito, Daniela Vianna [UNIFESP]
Cruz Latorraca, Carolina de Oliveira [UNIFESP]
Cabrera Martimbianco, Ana Luiza
Riera, Rachel [UNIFESP]
author_role author
author2 Rizzo, Luiz Eduardo [UNIFESP]
Sunahara, Camila Sa [UNIFESP]
Pachito, Daniela Vianna [UNIFESP]
Cruz Latorraca, Carolina de Oliveira [UNIFESP]
Cabrera Martimbianco, Ana Luiza
Riera, Rachel [UNIFESP]
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lyra, Larissa [UNIFESP]
Rizzo, Luiz Eduardo [UNIFESP]
Sunahara, Camila Sa [UNIFESP]
Pachito, Daniela Vianna [UNIFESP]
Cruz Latorraca, Carolina de Oliveira [UNIFESP]
Cabrera Martimbianco, Ana Luiza
Riera, Rachel [UNIFESP]
dc.subject.por.fl_str_mv Autism spectrum disorder
Therapeutics
Review [Publication type]
Evidence-based practice
Evidence-based medicine
topic Autism spectrum disorder
Therapeutics
Review [Publication type]
Evidence-based practice
Evidence-based medicine
description CONTEXT AND OBJECTIVE: Autism spectrum disorders (ASDs) include autistic disorder, Asperger's disorder and pervasive developmental disorder. The manifestations of ASDs can have an important impact on learning and social functioning that may persist during adulthood. The aim here was to summarize the evidence from Cochrane systematic reviews on interventions for ASDs. DESIGN AND SETTING: Review of systematic reviews, conducted within the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo. METHODS: We included and summarized the results from Cochrane systematic reviews on interventions for ASDs. RESULTS: Seventeen reviews were included. These found weak evidence of benefits from acupuncture, gluten and casein-free diets, early intensive behavioral interventions, music therapy, parent-mediated early interventions, social skill groups, Theory of Mind cognitive model, aripiprazole, risperidone, tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRI)
publishDate 2017
dc.date.none.fl_str_mv 2017
2020-07-17T14:02:43Z
2020-07-17T14:02:43Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1516-3180.2017.0058200317
Sao Paulo Medical Journal. Sao Paulo, v. 135, n. 2, p. 192-201, 2017.
10.1590/1516-3180.2017.0058200317
WOS000402009700017.pdf
1516-3180
https://repositorio.unifesp.br/handle/11600/54964
WOS:000402009700017
url http://dx.doi.org/10.1590/1516-3180.2017.0058200317
https://repositorio.unifesp.br/handle/11600/54964
identifier_str_mv Sao Paulo Medical Journal. Sao Paulo, v. 135, n. 2, p. 192-201, 2017.
10.1590/1516-3180.2017.0058200317
WOS000402009700017.pdf
1516-3180
WOS:000402009700017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Sao Paulo Medical Journal
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 192-201
application/pdf
dc.coverage.none.fl_str_mv Sao Paulo
dc.publisher.none.fl_str_mv Associacao Paulista Medicina
publisher.none.fl_str_mv Associacao Paulista Medicina
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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