Risk Factors Associated With Early Invasive Pulmonary Aspergillosis in Kidney Transplant Recipients: Results From a Multinational Matched Case-Control Study

• Autor(a) principal: Lopez-Medrano, F.
• Data de Publicação: 2016
• Outros Autores: Silva, J. T., Fernandez-Ruiz, M., Carver, P. L., van Delden, C., Merino, E., Perez-Saez, M. J., Montero, M., Coussement, J., de Abreu Mazzolin, M. [UNIFESP], Cervera, C., Santos, L., Sabe, N., Scemla, A., Cordero, E., Cruzado-Vega, L., Martin-Moreno, P. L., Len, O., Rudas, E., Ponce de Leon, A., Arriola, M., Lauzurica, R., David, M., Gonzalez-Rico, C., Henriquez-Palop, F., Fortun, J., Nucci, M., Manuel, O., Pano-Pardo, J. R., Montejo, M., Munoz, P., Sanchez-Sobrino, B., Mazuecos, A., Pascual, J., Horcajada, J. P., Lecompte, T., Lumbreras, C., Moreno, A., Carratala, J., Blanes, M., Hernandez, D., Hernandez-Mendez, E. A., Farinas, M. C., Perello-Carrascosa, M., Morales, J. M., Andres, A., Aguado, J. M.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1111/ajt.13735; https://repositorio.unifesp.br/handle/11600/57662
• topic: clinical research; practice; infectious disease; kidney transplantation; nephrology; infection and infectious agents; fungal; epidemiology

Risk factors for invasive pulmonary aspergillosis (IPA) after kidney transplantation have been poorly explored. We performed a multinational case-control study that included 51 kidney transplant (KT) recipients diagnosed with early (first 180 posttransplant days) IPA at 19 institutions between 2000 and 2013. Control recipients were matched (1:1 ratio) by center and date of transplantation. Overall mortality among cases was 60.8%, and 25.0% of living recipients experienced graft loss. Pretransplant diagnosis of chronic pulmonary obstructive disease (COPD