Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://dx.doi.org/10.1590/S0100-72032011000100003 https://repositorio.unifesp.br/handle/11600/6242 |
Resumo: | PURPOSE: to evaluate associations between parental exposure to pesticides and births with congenital defects in São Francisco Valley, as well as the demographic profile and the defects found. METHODS: in this case-control study, each case (newborns with congenital defects) had two controls (healthy newborns). The subjects were born in the city of Petrolina, in São Francisco Valley, in 2009. The sample consisted of 42 cases and 84 controls. Data were gathered by a structured questionnaire adapted from Latin-American Collaborative Study of Congenital Malformations (ECLAMC), with the addition of questions related to exposure to pesticides, analysis of the medical records and contact with the hospital's pediatrician. The χ2 test was performed with a significance level of 5% to identify the variables with the greatest differences between case and control groups. Odds Ratio (OR) for the sample was calculated, as well as the OR obtained by logistic regression analysis, and finally, multivariate logistic regression analysis was performed. RESULTS: there was a greater exposure to pesticides during pregnancy in infants with congenital defects compared to healthy subjects. Increased risk was observed when at least one parent was exposed to pesticides (adjusted OR = 1.3; 95%CI = 0.4 - 3.9). The sociodemographic variables associated with congenital defects were: low school level, low weight, prematurity, young parents, chronic diseases, and physical factors. Multiple malformations and defects of the musculoskeletal and nervous systems were more frequently found. CONCLUSIONS: the present study suggests an association between exposure to pesticides and the occurrence of congenital defects, although the data were not significant. |
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Defeitos congênitos e exposição a agrotóxicos no Vale do São FranciscoCongenital defects and exposure to pesticides in São Francisco ValleyCongenital abnormalitiesPesticides exposurreMaternal exposureInfant, newbornOccupational exposureRisk factorsAnormalidades congênitasExposição a praguicidasExposição maternaRecém-nascidoExposição ocupacionalFatores de riscoPURPOSE: to evaluate associations between parental exposure to pesticides and births with congenital defects in São Francisco Valley, as well as the demographic profile and the defects found. METHODS: in this case-control study, each case (newborns with congenital defects) had two controls (healthy newborns). The subjects were born in the city of Petrolina, in São Francisco Valley, in 2009. The sample consisted of 42 cases and 84 controls. Data were gathered by a structured questionnaire adapted from Latin-American Collaborative Study of Congenital Malformations (ECLAMC), with the addition of questions related to exposure to pesticides, analysis of the medical records and contact with the hospital's pediatrician. The χ2 test was performed with a significance level of 5% to identify the variables with the greatest differences between case and control groups. Odds Ratio (OR) for the sample was calculated, as well as the OR obtained by logistic regression analysis, and finally, multivariate logistic regression analysis was performed. RESULTS: there was a greater exposure to pesticides during pregnancy in infants with congenital defects compared to healthy subjects. Increased risk was observed when at least one parent was exposed to pesticides (adjusted OR = 1.3; 95%CI = 0.4 - 3.9). The sociodemographic variables associated with congenital defects were: low school level, low weight, prematurity, young parents, chronic diseases, and physical factors. Multiple malformations and defects of the musculoskeletal and nervous systems were more frequently found. CONCLUSIONS: the present study suggests an association between exposure to pesticides and the occurrence of congenital defects, although the data were not significant.OBJETIVO: avaliar a associação entre a exposição dos genitores aos agrotóxicos e nascimentos com defeitos congênitos no Vale do São Francisco, bem como o perfil sociodemográfico e os defeitos encontrados. MÉTODOS: estudo tipo caso-controle, sendo que para cada caso (recém-nascido com defeito congênito), eram dois controles (recém-nascidos saudáveis) nascidos na cidade de Petrolina, no Vale do São Francisco, em 2009. A amostra constou de 42 casos e 84 controles. Os dados formam colhidos com uso de questionário estruturado, adaptado do Estudo Colaborativo Latino-Americano de Malformações Congênitas (ECLAMC), acrescido de questões relacionadas à exposição aos agrotóxicos, análise do prontuário e contato com a pediatra do hospital. Foi realizado o teste do χ2 com nível de significância de 5% para identificar as variáveis com maiores diferenças entre os grupos caso e controle. Em seguida, foi calculado o Odds Ratio (OR) amostral, bem como o OR obtido por análise de regressão logística e, finalmente, realizou-se uma análise de regressão logística multivariada. RESULTADOS: houve maior exposição aos agrotóxicos durante a gestação em neonatos com defeitos congênitos se comparados aos saudáveis. Maior risco foi observado quando pelo menos um dos genitores foi exposto aos agrotóxicos (OR ajustado = 1,3; IC95% = 0,4-3,9). As variáveis sociodemográficas associadas aos defeitos congênitos foram: baixa escolaridade, baixo peso, prematuridade, genitores jovens, doenças crônicas e fatores físicos. Foram encontrados com maior frequência os polimalformados e os defeitos dos sistemas musculoesquelético e nervoso. CONCLUSÃO: o presente estudo, a despeito de não apresentar significância, sugere associação entre a exposição aos agrotóxicos e a ocorrência de defeitos congênitos.Universidade Federal do Vale do São Francisco Colegiado de Enfermagem Disciplina de Bases MorfofisiológicasUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Cirurgia PediátricaUniversidade Federal do Vale do São FranciscoHospital Memorial de PetrolinaUniversidade Federal do Vale do São Francisco Colegiado de MedicinaUNIFESP, EPM, Depto. de Cirurgia PediátricaSciELOFederação Brasileira das Sociedades de Ginecologia e ObstetríciaUniversidade Federal do Vale do São Francisco Colegiado de Enfermagem Disciplina de Bases MorfofisiológicasUniversidade Federal de São Paulo (UNIFESP)Universidade Federal do Vale do São FranciscoHospital Memorial de PetrolinaUniversidade Federal do Vale do São Francisco Colegiado de MedicinaSilva, Silvio Romero Gonçalves eMartins, Jose Luiz [UNIFESP]Seixas, SimoneSilva, Daniela Conceição Gomes Gonçalves eLemos, Sidney Pereira PintoLemos, Patrícia Veruska Barbosa2015-06-14T13:42:51Z2015-06-14T13:42:51Z2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion20-26application/pdfhttps://dx.doi.org/10.1590/S0100-72032011000100003Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 33, n. 1, p. 20-26, 2011.10.1590/S0100-72032011000100003S0100-72032011000100003.pdf0100-7203S0100-72032011000100003https://repositorio.unifesp.br/handle/11600/6242porRevista Brasileira de Ginecologia e Obstetríciainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-22T18:18:30Zoai:repositorio.unifesp.br/:11600/6242Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-22T18:18:30Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco Congenital defects and exposure to pesticides in São Francisco Valley |
title |
Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco |
spellingShingle |
Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco Silva, Silvio Romero Gonçalves e Congenital abnormalities Pesticides exposurre Maternal exposure Infant, newborn Occupational exposure Risk factors Anormalidades congênitas Exposição a praguicidas Exposição materna Recém-nascido Exposição ocupacional Fatores de risco |
title_short |
Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco |
title_full |
Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco |
title_fullStr |
Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco |
title_full_unstemmed |
Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco |
title_sort |
Defeitos congênitos e exposição a agrotóxicos no Vale do São Francisco |
author |
Silva, Silvio Romero Gonçalves e |
author_facet |
Silva, Silvio Romero Gonçalves e Martins, Jose Luiz [UNIFESP] Seixas, Simone Silva, Daniela Conceição Gomes Gonçalves e Lemos, Sidney Pereira Pinto Lemos, Patrícia Veruska Barbosa |
author_role |
author |
author2 |
Martins, Jose Luiz [UNIFESP] Seixas, Simone Silva, Daniela Conceição Gomes Gonçalves e Lemos, Sidney Pereira Pinto Lemos, Patrícia Veruska Barbosa |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal do Vale do São Francisco Colegiado de Enfermagem Disciplina de Bases Morfofisiológicas Universidade Federal de São Paulo (UNIFESP) Universidade Federal do Vale do São Francisco Hospital Memorial de Petrolina Universidade Federal do Vale do São Francisco Colegiado de Medicina |
dc.contributor.author.fl_str_mv |
Silva, Silvio Romero Gonçalves e Martins, Jose Luiz [UNIFESP] Seixas, Simone Silva, Daniela Conceição Gomes Gonçalves e Lemos, Sidney Pereira Pinto Lemos, Patrícia Veruska Barbosa |
dc.subject.por.fl_str_mv |
Congenital abnormalities Pesticides exposurre Maternal exposure Infant, newborn Occupational exposure Risk factors Anormalidades congênitas Exposição a praguicidas Exposição materna Recém-nascido Exposição ocupacional Fatores de risco |
topic |
Congenital abnormalities Pesticides exposurre Maternal exposure Infant, newborn Occupational exposure Risk factors Anormalidades congênitas Exposição a praguicidas Exposição materna Recém-nascido Exposição ocupacional Fatores de risco |
description |
PURPOSE: to evaluate associations between parental exposure to pesticides and births with congenital defects in São Francisco Valley, as well as the demographic profile and the defects found. METHODS: in this case-control study, each case (newborns with congenital defects) had two controls (healthy newborns). The subjects were born in the city of Petrolina, in São Francisco Valley, in 2009. The sample consisted of 42 cases and 84 controls. Data were gathered by a structured questionnaire adapted from Latin-American Collaborative Study of Congenital Malformations (ECLAMC), with the addition of questions related to exposure to pesticides, analysis of the medical records and contact with the hospital's pediatrician. The χ2 test was performed with a significance level of 5% to identify the variables with the greatest differences between case and control groups. Odds Ratio (OR) for the sample was calculated, as well as the OR obtained by logistic regression analysis, and finally, multivariate logistic regression analysis was performed. RESULTS: there was a greater exposure to pesticides during pregnancy in infants with congenital defects compared to healthy subjects. Increased risk was observed when at least one parent was exposed to pesticides (adjusted OR = 1.3; 95%CI = 0.4 - 3.9). The sociodemographic variables associated with congenital defects were: low school level, low weight, prematurity, young parents, chronic diseases, and physical factors. Multiple malformations and defects of the musculoskeletal and nervous systems were more frequently found. CONCLUSIONS: the present study suggests an association between exposure to pesticides and the occurrence of congenital defects, although the data were not significant. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-01-01 2015-06-14T13:42:51Z 2015-06-14T13:42:51Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://dx.doi.org/10.1590/S0100-72032011000100003 Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 33, n. 1, p. 20-26, 2011. 10.1590/S0100-72032011000100003 S0100-72032011000100003.pdf 0100-7203 S0100-72032011000100003 https://repositorio.unifesp.br/handle/11600/6242 |
url |
https://dx.doi.org/10.1590/S0100-72032011000100003 https://repositorio.unifesp.br/handle/11600/6242 |
identifier_str_mv |
Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 33, n. 1, p. 20-26, 2011. 10.1590/S0100-72032011000100003 S0100-72032011000100003.pdf 0100-7203 S0100-72032011000100003 |
dc.language.iso.fl_str_mv |
por |
language |
por |
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Revista Brasileira de Ginecologia e Obstetrícia |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
20-26 application/pdf |
dc.publisher.none.fl_str_mv |
Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
publisher.none.fl_str_mv |
Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
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reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
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Universidade Federal de São Paulo (UNIFESP) |
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UNIFESP |
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Repositório Institucional da UNIFESP |
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Repositório Institucional da UNIFESP |
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Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
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biblioteca.csp@unifesp.br |
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1814268310935568384 |