Manifestações da infecção pelo novo vírus influenza A (H1N1) na tomografia computadorizada de tórax

• Autor(a) principal: Verrastro, Carlos Gustavo Yuji [UNIFESP]
• Data de Publicação: 2009
• Outros Autores: Abreu Junior, Luiz de, Hitomi, Diego Ziotti, Antonio, Emerson Pelarigo, Neves, Rodrigo Azambuja [UNIFESP], D'Ippolito, Giuseppe [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0100-39842009000600005; http://repositorio.unifesp.br/handle/11600/5444
• topic: Influenza A virus; Influenza A (H1N1) virus subtype; Viral pneumonia; X-ray computed tomography; Vírus influenza A; Vírus influenza A subtipo H1N1; Pneumonia viral; Tomografia computadorizada por raios X

OBJECTIVE: The objective of this study was to describe chest computed tomography findings in confirmed cases of infection by the novel influenza A (H1N1) virus. MATERIALS AND METHODS: Computed tomography studies of nine patients with laboratory-confirmed infection by the novel influenza A (H1N1) virus were consensually evaluated by three observers. The sample of the present study included five male and four female patients with ages ranging from 14 to 64 years (mean, 40 years). Four of the patients were previously healthy, four were kidney transplant recipients and one was pregnant at the time of diagnosis. Presence, extent and distribution of the following findings were evaluated: a) ground-glass opacities; b) centrilobular nodules; c) consolidation; d) interlobular septa thickening; e) pleural effusion; f) lymphadenopathy. RESULTS: The most frequent findings were ground-glass opacities, centrilobular nodules and consolidations, present in nine (100%), five (55%) and four (44%) of cases, respectively. Pleural effusions and lymphadenopathy were less common findings, occurring in only two (22%) of the cases. CONCLUSION: Ground-glass opacities, centrilobular nodules and consolidation were the most frequent findings in cases of infection by the novel influenza A (H1N1) virus. These changes are not typical or unique to this agent and may also occur in other viral or bacterial infections.