Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction

Detalhes bibliográficos
Autor(a) principal: Andrade, Enrico de
Data de Publicação: 2007
Outros Autores: Mesquita, Alexandre A. de, Claro, Joaquim de Almeida [UNIFESP], Andrade, Priscila M. de, Ortiz, Valdemar [UNIFESP], Paranhos, Mario, Srougi, Miguel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x
http://repositorio.unifesp.br/handle/11600/29519
Resumo: Aim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED.
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spelling Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunctionpenisimpotenceginsengpenile erectionAim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED.Univ São Paulo, Div Urol Clin, Sector Sexual Med, São Paulo, BrazilUniversidade Federal de São Paulo, Discipline Urol, São Paulo, BrazilUniversidade Federal de São Paulo, Discipline Urol, São Paulo, BrazilWeb of ScienceBlackwell PublishingUniversidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)Andrade, Enrico deMesquita, Alexandre A. deClaro, Joaquim de Almeida [UNIFESP]Andrade, Priscila M. deOrtiz, Valdemar [UNIFESP]Paranhos, MarioSrougi, Miguel2016-01-24T12:41:53Z2016-01-24T12:41:53Z2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion241-244application/pdfhttp://dx.doi.org/10.1111/j.1745-7262.2007.00210.xAsian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007.10.1111/j.1745-7262.2007.00210.xWOS000244880800010.pdf1008-682Xhttp://repositorio.unifesp.br/handle/11600/29519WOS:000244880800010engAsian Journal of Andrologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-07T15:03:49Zoai:repositorio.unifesp.br/:11600/29519Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-07T15:03:49Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
title Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
spellingShingle Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
Andrade, Enrico de
penis
impotence
ginseng
penile erection
title_short Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
title_full Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
title_fullStr Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
title_full_unstemmed Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
title_sort Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
author Andrade, Enrico de
author_facet Andrade, Enrico de
Mesquita, Alexandre A. de
Claro, Joaquim de Almeida [UNIFESP]
Andrade, Priscila M. de
Ortiz, Valdemar [UNIFESP]
Paranhos, Mario
Srougi, Miguel
author_role author
author2 Mesquita, Alexandre A. de
Claro, Joaquim de Almeida [UNIFESP]
Andrade, Priscila M. de
Ortiz, Valdemar [UNIFESP]
Paranhos, Mario
Srougi, Miguel
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Andrade, Enrico de
Mesquita, Alexandre A. de
Claro, Joaquim de Almeida [UNIFESP]
Andrade, Priscila M. de
Ortiz, Valdemar [UNIFESP]
Paranhos, Mario
Srougi, Miguel
dc.subject.por.fl_str_mv penis
impotence
ginseng
penile erection
topic penis
impotence
ginseng
penile erection
description Aim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED.
publishDate 2007
dc.date.none.fl_str_mv 2007-03-01
2016-01-24T12:41:53Z
2016-01-24T12:41:53Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x
Asian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007.
10.1111/j.1745-7262.2007.00210.x
WOS000244880800010.pdf
1008-682X
http://repositorio.unifesp.br/handle/11600/29519
WOS:000244880800010
url http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x
http://repositorio.unifesp.br/handle/11600/29519
identifier_str_mv Asian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007.
10.1111/j.1745-7262.2007.00210.x
WOS000244880800010.pdf
1008-682X
WOS:000244880800010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Asian Journal of Andrology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 241-244
application/pdf
dc.publisher.none.fl_str_mv Blackwell Publishing
publisher.none.fl_str_mv Blackwell Publishing
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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