Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x http://repositorio.unifesp.br/handle/11600/29519 |
Resumo: | Aim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED. |
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Repositório Institucional da UNIFESP |
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Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunctionpenisimpotenceginsengpenile erectionAim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED.Univ São Paulo, Div Urol Clin, Sector Sexual Med, São Paulo, BrazilUniversidade Federal de São Paulo, Discipline Urol, São Paulo, BrazilUniversidade Federal de São Paulo, Discipline Urol, São Paulo, BrazilWeb of ScienceBlackwell PublishingUniversidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)Andrade, Enrico deMesquita, Alexandre A. deClaro, Joaquim de Almeida [UNIFESP]Andrade, Priscila M. deOrtiz, Valdemar [UNIFESP]Paranhos, MarioSrougi, Miguel2016-01-24T12:41:53Z2016-01-24T12:41:53Z2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion241-244application/pdfhttp://dx.doi.org/10.1111/j.1745-7262.2007.00210.xAsian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007.10.1111/j.1745-7262.2007.00210.xWOS000244880800010.pdf1008-682Xhttp://repositorio.unifesp.br/handle/11600/29519WOS:000244880800010engAsian Journal of Andrologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-07T15:03:49Zoai:repositorio.unifesp.br/:11600/29519Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-07T15:03:49Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
spellingShingle |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction Andrade, Enrico de penis impotence ginseng penile erection |
title_short |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title_full |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title_fullStr |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title_full_unstemmed |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
title_sort |
Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction |
author |
Andrade, Enrico de |
author_facet |
Andrade, Enrico de Mesquita, Alexandre A. de Claro, Joaquim de Almeida [UNIFESP] Andrade, Priscila M. de Ortiz, Valdemar [UNIFESP] Paranhos, Mario Srougi, Miguel |
author_role |
author |
author2 |
Mesquita, Alexandre A. de Claro, Joaquim de Almeida [UNIFESP] Andrade, Priscila M. de Ortiz, Valdemar [UNIFESP] Paranhos, Mario Srougi, Miguel |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Andrade, Enrico de Mesquita, Alexandre A. de Claro, Joaquim de Almeida [UNIFESP] Andrade, Priscila M. de Ortiz, Valdemar [UNIFESP] Paranhos, Mario Srougi, Miguel |
dc.subject.por.fl_str_mv |
penis impotence ginseng penile erection |
topic |
penis impotence ginseng penile erection |
description |
Aim: To examine the treatment efficacy of Korean Red Ginseng (KRG) in impotent men with erectile dysfunction (ED). Methods: A total of 60 patients presenting mild or mild to moderate ED were enrolled in a double-blind, placebo-controlled study in which the efficacies of KRG and a placebo were compared. the patients received either 1 000 mg (3 times daily) of KRG or a placebo. Results: the five-item version of the International Index of Erectile Function (IIEF-5) score after the treatment was significantly higher in the KRG group compared with that before the treatment (from 16.4 +/- 2.9 to 21.0 +/- 6.3, P < 0.0001). in contrast, there was no difference before and after the treatment in the placebo group (from 17.0 +/- 3.1 to 17.7 +/- 5.6, P > 0.05). in the KRG group, 20 patients (66.6%), reported improved erection, significant in the global efficacy question (P < 0.01); in the placebo group there was no significance. Scores on questions 2 (rigidity), 3 (penetration), 4 and 5 (maintenance), were significantly higher for KRG than those for the placebo when those questions were answered after 12 weeks of each treatment (P < 0.01). When the score in the KRG group was compared to the placebo group after the treatment, there was a significant improvement in total score (IIEF-5 score) in questions 3 and 5 for the KRG-treated group (P < 0.001 and P < 0.0001, respectively). the levels of serum testosterone, prolactine and cholesterol after the treatment were not statistically significant different between the KRG and the placebo group (P > 0.05). Conclusion: Our data show that KRG can be an effective alternative to the invasive approaches for treating male ED. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-03-01 2016-01-24T12:41:53Z 2016-01-24T12:41:53Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x Asian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007. 10.1111/j.1745-7262.2007.00210.x WOS000244880800010.pdf 1008-682X http://repositorio.unifesp.br/handle/11600/29519 WOS:000244880800010 |
url |
http://dx.doi.org/10.1111/j.1745-7262.2007.00210.x http://repositorio.unifesp.br/handle/11600/29519 |
identifier_str_mv |
Asian Journal of Andrology. Oxford: Blackwell Publishing, v. 9, n. 2, p. 241-244, 2007. 10.1111/j.1745-7262.2007.00210.x WOS000244880800010.pdf 1008-682X WOS:000244880800010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Asian Journal of Andrology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
241-244 application/pdf |
dc.publisher.none.fl_str_mv |
Blackwell Publishing |
publisher.none.fl_str_mv |
Blackwell Publishing |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268315730706432 |