A predictive score for retinopathy of prematurity in very low birth weight preterm infants

Detalhes bibliográficos
Autor(a) principal: Eckert, Gabriela Unchalo
Data de Publicação: 2012
Outros Autores: Fortes Filho, Joao Borges, Maia, Mauricio [UNIFESP], Procianoy, Renato Soibelmann
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: https://dx.doi.org/10.1038/eye.2011.334
https://repositorio.unifesp.br/handle/11600/34638
Resumo: Aims This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to predict the onset of ROP.Methods A prospective cohort of preterm infants with BWp1500 g and/or GAp32 weeks was studied. the score was developed based on BW, GA, proportional weight gain from birth to the 6th week of life, use of oxygen in mechanical ventilation, and need for blood transfusions from birth to the 6th week of life. the score was established after linear regression, considering the impact of each variable on the occurrences of any stage and severe ROP. Receiver operating characteristic (ROC) curves were used to determine the best sensitivity and specificity values for the score. All variables were entered into an Excel spreadsheet (Microsoft) for practical use by ophthalmologists during screening sessions.Results the sample included 474 patients. the area under the ROC curve for the score was 0.77 and 0.88 to predict any stage and severe ROP, respectively. These values were significantly higher for the score than for BW (0.71) and GA (0.69) when measured separately.Conclusions ROPScore is an excellent index of neonatal risk factors for ROP, which is easy to record and more accurate than BW and GA to predict any stage ROP or severe ROP in preterm infants. the scoring system is simple enough to be routinely used by ophthalmologists during screening examination for detection of ROP. Eye (2012) 26, 400-406; doi: 10.1038/eye. 2011.334; published online 23 December 2011
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spelling A predictive score for retinopathy of prematurity in very low birth weight preterm infantsPrematurityRetinopathy of prematurityVery low birth weightRisk factorsSeverity illness scoreAims This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to predict the onset of ROP.Methods A prospective cohort of preterm infants with BWp1500 g and/or GAp32 weeks was studied. the score was developed based on BW, GA, proportional weight gain from birth to the 6th week of life, use of oxygen in mechanical ventilation, and need for blood transfusions from birth to the 6th week of life. the score was established after linear regression, considering the impact of each variable on the occurrences of any stage and severe ROP. Receiver operating characteristic (ROC) curves were used to determine the best sensitivity and specificity values for the score. All variables were entered into an Excel spreadsheet (Microsoft) for practical use by ophthalmologists during screening sessions.Results the sample included 474 patients. the area under the ROC curve for the score was 0.77 and 0.88 to predict any stage and severe ROP, respectively. These values were significantly higher for the score than for BW (0.71) and GA (0.69) when measured separately.Conclusions ROPScore is an excellent index of neonatal risk factors for ROP, which is easy to record and more accurate than BW and GA to predict any stage ROP or severe ROP in preterm infants. the scoring system is simple enough to be routinely used by ophthalmologists during screening examination for detection of ROP. Eye (2012) 26, 400-406; doi: 10.1038/eye. 2011.334; published online 23 December 2011Hosp Clin Porto Alegre, Dept Ophthalmol, BR-90035903 Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Dept Ophthalmol, Sch Med, Porto Alegre, RS, BrazilUniversidade Federal de São Paulo, Dept Ophthalmol, Sch Med, São Paulo, BrazilUniv Fed Rio Grande do Sul, Dept Paediat, Newborn Sect, Sch Med, Porto Alegre, RS, BrazilUniversidade Federal de São Paulo, Dept Ophthalmol, Sch Med, São Paulo, BrazilWeb of ScienceNature Publishing GroupHosp Clin Porto AlegreUniv Fed Rio Grande do SulUniversidade Federal de São Paulo (UNIFESP)Eckert, Gabriela UnchaloFortes Filho, Joao BorgesMaia, Mauricio [UNIFESP]Procianoy, Renato Soibelmann2016-01-24T14:17:56Z2016-01-24T14:17:56Z2012-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion400-406https://dx.doi.org/10.1038/eye.2011.334Eye. London: Nature Publishing Group, v. 26, n. 3, p. 400-406, 2012.10.1038/eye.2011.3340950-222Xhttps://repositorio.unifesp.br/handle/11600/34638WOS:000301428900007engEyeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2023-10-18T19:42:58Zoai:repositorio.unifesp.br/:11600/34638Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652023-10-18T19:42:58Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv A predictive score for retinopathy of prematurity in very low birth weight preterm infants
title A predictive score for retinopathy of prematurity in very low birth weight preterm infants
spellingShingle A predictive score for retinopathy of prematurity in very low birth weight preterm infants
Eckert, Gabriela Unchalo
Prematurity
Retinopathy of prematurity
Very low birth weight
Risk factors
Severity illness score
title_short A predictive score for retinopathy of prematurity in very low birth weight preterm infants
title_full A predictive score for retinopathy of prematurity in very low birth weight preterm infants
title_fullStr A predictive score for retinopathy of prematurity in very low birth weight preterm infants
title_full_unstemmed A predictive score for retinopathy of prematurity in very low birth weight preterm infants
title_sort A predictive score for retinopathy of prematurity in very low birth weight preterm infants
author Eckert, Gabriela Unchalo
author_facet Eckert, Gabriela Unchalo
Fortes Filho, Joao Borges
Maia, Mauricio [UNIFESP]
Procianoy, Renato Soibelmann
author_role author
author2 Fortes Filho, Joao Borges
Maia, Mauricio [UNIFESP]
Procianoy, Renato Soibelmann
author2_role author
author
author
dc.contributor.none.fl_str_mv Hosp Clin Porto Alegre
Univ Fed Rio Grande do Sul
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Eckert, Gabriela Unchalo
Fortes Filho, Joao Borges
Maia, Mauricio [UNIFESP]
Procianoy, Renato Soibelmann
dc.subject.por.fl_str_mv Prematurity
Retinopathy of prematurity
Very low birth weight
Risk factors
Severity illness score
topic Prematurity
Retinopathy of prematurity
Very low birth weight
Risk factors
Severity illness score
description Aims This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to predict the onset of ROP.Methods A prospective cohort of preterm infants with BWp1500 g and/or GAp32 weeks was studied. the score was developed based on BW, GA, proportional weight gain from birth to the 6th week of life, use of oxygen in mechanical ventilation, and need for blood transfusions from birth to the 6th week of life. the score was established after linear regression, considering the impact of each variable on the occurrences of any stage and severe ROP. Receiver operating characteristic (ROC) curves were used to determine the best sensitivity and specificity values for the score. All variables were entered into an Excel spreadsheet (Microsoft) for practical use by ophthalmologists during screening sessions.Results the sample included 474 patients. the area under the ROC curve for the score was 0.77 and 0.88 to predict any stage and severe ROP, respectively. These values were significantly higher for the score than for BW (0.71) and GA (0.69) when measured separately.Conclusions ROPScore is an excellent index of neonatal risk factors for ROP, which is easy to record and more accurate than BW and GA to predict any stage ROP or severe ROP in preterm infants. the scoring system is simple enough to be routinely used by ophthalmologists during screening examination for detection of ROP. Eye (2012) 26, 400-406; doi: 10.1038/eye. 2011.334; published online 23 December 2011
publishDate 2012
dc.date.none.fl_str_mv 2012-03-01
2016-01-24T14:17:56Z
2016-01-24T14:17:56Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://dx.doi.org/10.1038/eye.2011.334
Eye. London: Nature Publishing Group, v. 26, n. 3, p. 400-406, 2012.
10.1038/eye.2011.334
0950-222X
https://repositorio.unifesp.br/handle/11600/34638
WOS:000301428900007
url https://dx.doi.org/10.1038/eye.2011.334
https://repositorio.unifesp.br/handle/11600/34638
identifier_str_mv Eye. London: Nature Publishing Group, v. 26, n. 3, p. 400-406, 2012.
10.1038/eye.2011.334
0950-222X
WOS:000301428900007
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Eye
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 400-406
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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