A predictive score for retinopathy of prematurity in very low birth weight preterm infants
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://dx.doi.org/10.1038/eye.2011.334 https://repositorio.unifesp.br/handle/11600/34638 |
Resumo: | Aims This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to predict the onset of ROP.Methods A prospective cohort of preterm infants with BWp1500 g and/or GAp32 weeks was studied. the score was developed based on BW, GA, proportional weight gain from birth to the 6th week of life, use of oxygen in mechanical ventilation, and need for blood transfusions from birth to the 6th week of life. the score was established after linear regression, considering the impact of each variable on the occurrences of any stage and severe ROP. Receiver operating characteristic (ROC) curves were used to determine the best sensitivity and specificity values for the score. All variables were entered into an Excel spreadsheet (Microsoft) for practical use by ophthalmologists during screening sessions.Results the sample included 474 patients. the area under the ROC curve for the score was 0.77 and 0.88 to predict any stage and severe ROP, respectively. These values were significantly higher for the score than for BW (0.71) and GA (0.69) when measured separately.Conclusions ROPScore is an excellent index of neonatal risk factors for ROP, which is easy to record and more accurate than BW and GA to predict any stage ROP or severe ROP in preterm infants. the scoring system is simple enough to be routinely used by ophthalmologists during screening examination for detection of ROP. Eye (2012) 26, 400-406; doi: 10.1038/eye. 2011.334; published online 23 December 2011 |
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A predictive score for retinopathy of prematurity in very low birth weight preterm infantsPrematurityRetinopathy of prematurityVery low birth weightRisk factorsSeverity illness scoreAims This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to predict the onset of ROP.Methods A prospective cohort of preterm infants with BWp1500 g and/or GAp32 weeks was studied. the score was developed based on BW, GA, proportional weight gain from birth to the 6th week of life, use of oxygen in mechanical ventilation, and need for blood transfusions from birth to the 6th week of life. the score was established after linear regression, considering the impact of each variable on the occurrences of any stage and severe ROP. Receiver operating characteristic (ROC) curves were used to determine the best sensitivity and specificity values for the score. All variables were entered into an Excel spreadsheet (Microsoft) for practical use by ophthalmologists during screening sessions.Results the sample included 474 patients. the area under the ROC curve for the score was 0.77 and 0.88 to predict any stage and severe ROP, respectively. These values were significantly higher for the score than for BW (0.71) and GA (0.69) when measured separately.Conclusions ROPScore is an excellent index of neonatal risk factors for ROP, which is easy to record and more accurate than BW and GA to predict any stage ROP or severe ROP in preterm infants. the scoring system is simple enough to be routinely used by ophthalmologists during screening examination for detection of ROP. Eye (2012) 26, 400-406; doi: 10.1038/eye. 2011.334; published online 23 December 2011Hosp Clin Porto Alegre, Dept Ophthalmol, BR-90035903 Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Dept Ophthalmol, Sch Med, Porto Alegre, RS, BrazilUniversidade Federal de São Paulo, Dept Ophthalmol, Sch Med, São Paulo, BrazilUniv Fed Rio Grande do Sul, Dept Paediat, Newborn Sect, Sch Med, Porto Alegre, RS, BrazilUniversidade Federal de São Paulo, Dept Ophthalmol, Sch Med, São Paulo, BrazilWeb of ScienceNature Publishing GroupHosp Clin Porto AlegreUniv Fed Rio Grande do SulUniversidade Federal de São Paulo (UNIFESP)Eckert, Gabriela UnchaloFortes Filho, Joao BorgesMaia, Mauricio [UNIFESP]Procianoy, Renato Soibelmann2016-01-24T14:17:56Z2016-01-24T14:17:56Z2012-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion400-406https://dx.doi.org/10.1038/eye.2011.334Eye. London: Nature Publishing Group, v. 26, n. 3, p. 400-406, 2012.10.1038/eye.2011.3340950-222Xhttps://repositorio.unifesp.br/handle/11600/34638WOS:000301428900007engEyeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2023-10-18T19:42:58Zoai:repositorio.unifesp.br/:11600/34638Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652023-10-18T19:42:58Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
A predictive score for retinopathy of prematurity in very low birth weight preterm infants |
title |
A predictive score for retinopathy of prematurity in very low birth weight preterm infants |
spellingShingle |
A predictive score for retinopathy of prematurity in very low birth weight preterm infants Eckert, Gabriela Unchalo Prematurity Retinopathy of prematurity Very low birth weight Risk factors Severity illness score |
title_short |
A predictive score for retinopathy of prematurity in very low birth weight preterm infants |
title_full |
A predictive score for retinopathy of prematurity in very low birth weight preterm infants |
title_fullStr |
A predictive score for retinopathy of prematurity in very low birth weight preterm infants |
title_full_unstemmed |
A predictive score for retinopathy of prematurity in very low birth weight preterm infants |
title_sort |
A predictive score for retinopathy of prematurity in very low birth weight preterm infants |
author |
Eckert, Gabriela Unchalo |
author_facet |
Eckert, Gabriela Unchalo Fortes Filho, Joao Borges Maia, Mauricio [UNIFESP] Procianoy, Renato Soibelmann |
author_role |
author |
author2 |
Fortes Filho, Joao Borges Maia, Mauricio [UNIFESP] Procianoy, Renato Soibelmann |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Hosp Clin Porto Alegre Univ Fed Rio Grande do Sul Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Eckert, Gabriela Unchalo Fortes Filho, Joao Borges Maia, Mauricio [UNIFESP] Procianoy, Renato Soibelmann |
dc.subject.por.fl_str_mv |
Prematurity Retinopathy of prematurity Very low birth weight Risk factors Severity illness score |
topic |
Prematurity Retinopathy of prematurity Very low birth weight Risk factors Severity illness score |
description |
Aims This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to predict the onset of ROP.Methods A prospective cohort of preterm infants with BWp1500 g and/or GAp32 weeks was studied. the score was developed based on BW, GA, proportional weight gain from birth to the 6th week of life, use of oxygen in mechanical ventilation, and need for blood transfusions from birth to the 6th week of life. the score was established after linear regression, considering the impact of each variable on the occurrences of any stage and severe ROP. Receiver operating characteristic (ROC) curves were used to determine the best sensitivity and specificity values for the score. All variables were entered into an Excel spreadsheet (Microsoft) for practical use by ophthalmologists during screening sessions.Results the sample included 474 patients. the area under the ROC curve for the score was 0.77 and 0.88 to predict any stage and severe ROP, respectively. These values were significantly higher for the score than for BW (0.71) and GA (0.69) when measured separately.Conclusions ROPScore is an excellent index of neonatal risk factors for ROP, which is easy to record and more accurate than BW and GA to predict any stage ROP or severe ROP in preterm infants. the scoring system is simple enough to be routinely used by ophthalmologists during screening examination for detection of ROP. Eye (2012) 26, 400-406; doi: 10.1038/eye. 2011.334; published online 23 December 2011 |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-03-01 2016-01-24T14:17:56Z 2016-01-24T14:17:56Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://dx.doi.org/10.1038/eye.2011.334 Eye. London: Nature Publishing Group, v. 26, n. 3, p. 400-406, 2012. 10.1038/eye.2011.334 0950-222X https://repositorio.unifesp.br/handle/11600/34638 WOS:000301428900007 |
url |
https://dx.doi.org/10.1038/eye.2011.334 https://repositorio.unifesp.br/handle/11600/34638 |
identifier_str_mv |
Eye. London: Nature Publishing Group, v. 26, n. 3, p. 400-406, 2012. 10.1038/eye.2011.334 0950-222X WOS:000301428900007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Eye |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
400-406 |
dc.publisher.none.fl_str_mv |
Nature Publishing Group |
publisher.none.fl_str_mv |
Nature Publishing Group |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268442668171264 |