Early light reduction for preventing retinopathy of prematurity in very low birth weight infants

Detalhes bibliográficos
Autor(a) principal: Jorge, Eliane Chaves [UNESP]
Data de Publicação: 2013
Outros Autores: Jorge, Edson Nacib [UNESP], Dib, Regina Paolucci El [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1002/14651858.CD000122.pub2
http://hdl.handle.net/11449/112286
Resumo: BackgroundRetinopathy of prematurity (ROP) is a complex condition of the developing retinal blood vessels and is one of the leading causes of preventable childhood blindness. Several risk factors for ROP have been studied over the past 50 years. Among them, general immaturity (low birth weight and low gestational age) and prolonged oxygen therapy have been consistently related to disease onset. However, it is understood that the progression of the disease is multifactorial and may be associated with others risk factors, such as multiple gestation, apnoea, intracranial haemorrhage, anaemia, sepsis, prolonged mechanical ventilation, multiple transfusions and light exposure. Furthermore, the precise role of these individual factors in the development of the disease has not yet been well established.ObjectivesTo determine whether the reduction of early environmental light exposure reduces the incidence of retinopathy of prematurity (ROP) or poor ROP outcomes among very low birth weight infants.Search methodsWe searched the following databases: the Cochrane Neonatal Group Specialised Register, CENTRAL (The Cochrane Library), MEDLINE, EMBASE, CINAHL, HealthSTAR, Science Citation Index Database, CANCERLIT, the Oxford Database of Perinatal Trials and www.clinicaltrials.gov. We also searched previous reviews including cross-references, abstracts, conference and symposia proceedings, and contacted expert informants. This search was updated in October 2012.Selection criteriaRandomised or quasi-randomised controlled trials that reduced light exposure to premature infants within the first seven days following birth were considered for this review. We also considered cluster-randomised controlled trials.Data collection and analysisData on clinical outcomes including any acute ROP and poor ROP outcome were extracted by both review authors independently and consensus reached. We conducted data analysis according to the standards of the Cochrane Neonatal Review Group.Main resultsData from four randomised trials with a total of 897 participants failed to show any reduction in acute ROP or poor ROP outcome with the reduction of ambient light to premature infants' retinas. The overall methodological quality of the included studies was about evenly split between those in which the classification was unclear and those in which the studies were categorised as low risk of bias. There was no report on the secondary outcomes considered in this review: quality of life measures; and time of exposure to oxygen.Authors' conclusionsThe evidence shows that bright light is not the cause of retinopathy of prematurity and that the reduction of exposure of the retinas of premature infants to light has no effect on the incidence of the disease.
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spelling Early light reduction for preventing retinopathy of prematurity in very low birth weight infantsLightingInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightRandomized Controlled Trials as TopicRetinopathy of Prematurity [prevention & control]HumansBackgroundRetinopathy of prematurity (ROP) is a complex condition of the developing retinal blood vessels and is one of the leading causes of preventable childhood blindness. Several risk factors for ROP have been studied over the past 50 years. Among them, general immaturity (low birth weight and low gestational age) and prolonged oxygen therapy have been consistently related to disease onset. However, it is understood that the progression of the disease is multifactorial and may be associated with others risk factors, such as multiple gestation, apnoea, intracranial haemorrhage, anaemia, sepsis, prolonged mechanical ventilation, multiple transfusions and light exposure. Furthermore, the precise role of these individual factors in the development of the disease has not yet been well established.ObjectivesTo determine whether the reduction of early environmental light exposure reduces the incidence of retinopathy of prematurity (ROP) or poor ROP outcomes among very low birth weight infants.Search methodsWe searched the following databases: the Cochrane Neonatal Group Specialised Register, CENTRAL (The Cochrane Library), MEDLINE, EMBASE, CINAHL, HealthSTAR, Science Citation Index Database, CANCERLIT, the Oxford Database of Perinatal Trials and www.clinicaltrials.gov. We also searched previous reviews including cross-references, abstracts, conference and symposia proceedings, and contacted expert informants. This search was updated in October 2012.Selection criteriaRandomised or quasi-randomised controlled trials that reduced light exposure to premature infants within the first seven days following birth were considered for this review. We also considered cluster-randomised controlled trials.Data collection and analysisData on clinical outcomes including any acute ROP and poor ROP outcome were extracted by both review authors independently and consensus reached. We conducted data analysis according to the standards of the Cochrane Neonatal Review Group.Main resultsData from four randomised trials with a total of 897 participants failed to show any reduction in acute ROP or poor ROP outcome with the reduction of ambient light to premature infants' retinas. The overall methodological quality of the included studies was about evenly split between those in which the classification was unclear and those in which the studies were categorised as low risk of bias. There was no report on the secondary outcomes considered in this review: quality of life measures; and time of exposure to oxygen.Authors' conclusionsThe evidence shows that bright light is not the cause of retinopathy of prematurity and that the reduction of exposure of the retinas of premature infants to light has no effect on the incidence of the disease.University of Rochester, NY, USAEunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USAUniv Estadual Paulista UNESP, Dept Ophthalmol Otorhinolaryngol & Head & Neck Su, Botucatu Med Sch, Botucatu, SP, BrazilUNESP Univ Estadual Paulista, Dept Anaesthesiol, Botucatu Med Sch, Botucatu, SP, BrazilUniv Estadual Paulista UNESP, Dept Ophthalmol Otorhinolaryngol & Head & Neck Su, Botucatu Med Sch, Botucatu, SP, BrazilUNESP Univ Estadual Paulista, Dept Anaesthesiol, Botucatu Med Sch, Botucatu, SP, BrazilEunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USAHHSN275201100016CWiley-BlackwellUniversidade Estadual Paulista (Unesp)Jorge, Eliane Chaves [UNESP]Jorge, Edson Nacib [UNESP]Dib, Regina Paolucci El [UNESP]2014-12-03T13:10:35Z2014-12-03T13:10:35Z2013-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article31http://dx.doi.org/10.1002/14651858.CD000122.pub2Cochrane Database Of Systematic Reviews. Hoboken: Wiley-blackwell, n. 8, 31 p., 2013.1469-493Xhttp://hdl.handle.net/11449/11228610.1002/14651858.CD000122.pub2WOS:000323928600002026012048635593466922279033003800000-0003-3121-440X0000-0002-4081-803X0000-0002-9362-1505Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCochrane Database of Systematic Reviews6.754info:eu-repo/semantics/openAccess2024-08-16T18:44:44Zoai:repositorio.unesp.br:11449/112286Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T18:44:44Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
title Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
spellingShingle Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
Jorge, Eliane Chaves [UNESP]
Lighting
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Randomized Controlled Trials as Topic
Retinopathy of Prematurity [prevention & control]
Humans
title_short Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
title_full Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
title_fullStr Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
title_full_unstemmed Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
title_sort Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
author Jorge, Eliane Chaves [UNESP]
author_facet Jorge, Eliane Chaves [UNESP]
Jorge, Edson Nacib [UNESP]
Dib, Regina Paolucci El [UNESP]
author_role author
author2 Jorge, Edson Nacib [UNESP]
Dib, Regina Paolucci El [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Jorge, Eliane Chaves [UNESP]
Jorge, Edson Nacib [UNESP]
Dib, Regina Paolucci El [UNESP]
dc.subject.por.fl_str_mv Lighting
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Randomized Controlled Trials as Topic
Retinopathy of Prematurity [prevention & control]
Humans
topic Lighting
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Randomized Controlled Trials as Topic
Retinopathy of Prematurity [prevention & control]
Humans
description BackgroundRetinopathy of prematurity (ROP) is a complex condition of the developing retinal blood vessels and is one of the leading causes of preventable childhood blindness. Several risk factors for ROP have been studied over the past 50 years. Among them, general immaturity (low birth weight and low gestational age) and prolonged oxygen therapy have been consistently related to disease onset. However, it is understood that the progression of the disease is multifactorial and may be associated with others risk factors, such as multiple gestation, apnoea, intracranial haemorrhage, anaemia, sepsis, prolonged mechanical ventilation, multiple transfusions and light exposure. Furthermore, the precise role of these individual factors in the development of the disease has not yet been well established.ObjectivesTo determine whether the reduction of early environmental light exposure reduces the incidence of retinopathy of prematurity (ROP) or poor ROP outcomes among very low birth weight infants.Search methodsWe searched the following databases: the Cochrane Neonatal Group Specialised Register, CENTRAL (The Cochrane Library), MEDLINE, EMBASE, CINAHL, HealthSTAR, Science Citation Index Database, CANCERLIT, the Oxford Database of Perinatal Trials and www.clinicaltrials.gov. We also searched previous reviews including cross-references, abstracts, conference and symposia proceedings, and contacted expert informants. This search was updated in October 2012.Selection criteriaRandomised or quasi-randomised controlled trials that reduced light exposure to premature infants within the first seven days following birth were considered for this review. We also considered cluster-randomised controlled trials.Data collection and analysisData on clinical outcomes including any acute ROP and poor ROP outcome were extracted by both review authors independently and consensus reached. We conducted data analysis according to the standards of the Cochrane Neonatal Review Group.Main resultsData from four randomised trials with a total of 897 participants failed to show any reduction in acute ROP or poor ROP outcome with the reduction of ambient light to premature infants' retinas. The overall methodological quality of the included studies was about evenly split between those in which the classification was unclear and those in which the studies were categorised as low risk of bias. There was no report on the secondary outcomes considered in this review: quality of life measures; and time of exposure to oxygen.Authors' conclusionsThe evidence shows that bright light is not the cause of retinopathy of prematurity and that the reduction of exposure of the retinas of premature infants to light has no effect on the incidence of the disease.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
2014-12-03T13:10:35Z
2014-12-03T13:10:35Z
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format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1002/14651858.CD000122.pub2
Cochrane Database Of Systematic Reviews. Hoboken: Wiley-blackwell, n. 8, 31 p., 2013.
1469-493X
http://hdl.handle.net/11449/112286
10.1002/14651858.CD000122.pub2
WOS:000323928600002
0260120486355934
6692227903300380
0000-0003-3121-440X
0000-0002-4081-803X
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url http://dx.doi.org/10.1002/14651858.CD000122.pub2
http://hdl.handle.net/11449/112286
identifier_str_mv Cochrane Database Of Systematic Reviews. Hoboken: Wiley-blackwell, n. 8, 31 p., 2013.
1469-493X
10.1002/14651858.CD000122.pub2
WOS:000323928600002
0260120486355934
6692227903300380
0000-0003-3121-440X
0000-0002-4081-803X
0000-0002-9362-1505
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Cochrane Database of Systematic Reviews
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dc.publisher.none.fl_str_mv Wiley-Blackwell
publisher.none.fl_str_mv Wiley-Blackwell
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
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