Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1002/14651858.CD000122.pub2 http://hdl.handle.net/11449/112286 |
Resumo: | BackgroundRetinopathy of prematurity (ROP) is a complex condition of the developing retinal blood vessels and is one of the leading causes of preventable childhood blindness. Several risk factors for ROP have been studied over the past 50 years. Among them, general immaturity (low birth weight and low gestational age) and prolonged oxygen therapy have been consistently related to disease onset. However, it is understood that the progression of the disease is multifactorial and may be associated with others risk factors, such as multiple gestation, apnoea, intracranial haemorrhage, anaemia, sepsis, prolonged mechanical ventilation, multiple transfusions and light exposure. Furthermore, the precise role of these individual factors in the development of the disease has not yet been well established.ObjectivesTo determine whether the reduction of early environmental light exposure reduces the incidence of retinopathy of prematurity (ROP) or poor ROP outcomes among very low birth weight infants.Search methodsWe searched the following databases: the Cochrane Neonatal Group Specialised Register, CENTRAL (The Cochrane Library), MEDLINE, EMBASE, CINAHL, HealthSTAR, Science Citation Index Database, CANCERLIT, the Oxford Database of Perinatal Trials and www.clinicaltrials.gov. We also searched previous reviews including cross-references, abstracts, conference and symposia proceedings, and contacted expert informants. This search was updated in October 2012.Selection criteriaRandomised or quasi-randomised controlled trials that reduced light exposure to premature infants within the first seven days following birth were considered for this review. We also considered cluster-randomised controlled trials.Data collection and analysisData on clinical outcomes including any acute ROP and poor ROP outcome were extracted by both review authors independently and consensus reached. We conducted data analysis according to the standards of the Cochrane Neonatal Review Group.Main resultsData from four randomised trials with a total of 897 participants failed to show any reduction in acute ROP or poor ROP outcome with the reduction of ambient light to premature infants' retinas. The overall methodological quality of the included studies was about evenly split between those in which the classification was unclear and those in which the studies were categorised as low risk of bias. There was no report on the secondary outcomes considered in this review: quality of life measures; and time of exposure to oxygen.Authors' conclusionsThe evidence shows that bright light is not the cause of retinopathy of prematurity and that the reduction of exposure of the retinas of premature infants to light has no effect on the incidence of the disease. |
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Early light reduction for preventing retinopathy of prematurity in very low birth weight infantsLightingInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightRandomized Controlled Trials as TopicRetinopathy of Prematurity [prevention & control]HumansBackgroundRetinopathy of prematurity (ROP) is a complex condition of the developing retinal blood vessels and is one of the leading causes of preventable childhood blindness. Several risk factors for ROP have been studied over the past 50 years. Among them, general immaturity (low birth weight and low gestational age) and prolonged oxygen therapy have been consistently related to disease onset. However, it is understood that the progression of the disease is multifactorial and may be associated with others risk factors, such as multiple gestation, apnoea, intracranial haemorrhage, anaemia, sepsis, prolonged mechanical ventilation, multiple transfusions and light exposure. Furthermore, the precise role of these individual factors in the development of the disease has not yet been well established.ObjectivesTo determine whether the reduction of early environmental light exposure reduces the incidence of retinopathy of prematurity (ROP) or poor ROP outcomes among very low birth weight infants.Search methodsWe searched the following databases: the Cochrane Neonatal Group Specialised Register, CENTRAL (The Cochrane Library), MEDLINE, EMBASE, CINAHL, HealthSTAR, Science Citation Index Database, CANCERLIT, the Oxford Database of Perinatal Trials and www.clinicaltrials.gov. We also searched previous reviews including cross-references, abstracts, conference and symposia proceedings, and contacted expert informants. This search was updated in October 2012.Selection criteriaRandomised or quasi-randomised controlled trials that reduced light exposure to premature infants within the first seven days following birth were considered for this review. We also considered cluster-randomised controlled trials.Data collection and analysisData on clinical outcomes including any acute ROP and poor ROP outcome were extracted by both review authors independently and consensus reached. We conducted data analysis according to the standards of the Cochrane Neonatal Review Group.Main resultsData from four randomised trials with a total of 897 participants failed to show any reduction in acute ROP or poor ROP outcome with the reduction of ambient light to premature infants' retinas. The overall methodological quality of the included studies was about evenly split between those in which the classification was unclear and those in which the studies were categorised as low risk of bias. There was no report on the secondary outcomes considered in this review: quality of life measures; and time of exposure to oxygen.Authors' conclusionsThe evidence shows that bright light is not the cause of retinopathy of prematurity and that the reduction of exposure of the retinas of premature infants to light has no effect on the incidence of the disease.University of Rochester, NY, USAEunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USAUniv Estadual Paulista UNESP, Dept Ophthalmol Otorhinolaryngol & Head & Neck Su, Botucatu Med Sch, Botucatu, SP, BrazilUNESP Univ Estadual Paulista, Dept Anaesthesiol, Botucatu Med Sch, Botucatu, SP, BrazilUniv Estadual Paulista UNESP, Dept Ophthalmol Otorhinolaryngol & Head & Neck Su, Botucatu Med Sch, Botucatu, SP, BrazilUNESP Univ Estadual Paulista, Dept Anaesthesiol, Botucatu Med Sch, Botucatu, SP, BrazilEunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USAHHSN275201100016CWiley-BlackwellUniversidade Estadual Paulista (Unesp)Jorge, Eliane Chaves [UNESP]Jorge, Edson Nacib [UNESP]Dib, Regina Paolucci El [UNESP]2014-12-03T13:10:35Z2014-12-03T13:10:35Z2013-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article31http://dx.doi.org/10.1002/14651858.CD000122.pub2Cochrane Database Of Systematic Reviews. Hoboken: Wiley-blackwell, n. 8, 31 p., 2013.1469-493Xhttp://hdl.handle.net/11449/11228610.1002/14651858.CD000122.pub2WOS:000323928600002026012048635593466922279033003800000-0003-3121-440X0000-0002-4081-803X0000-0002-9362-1505Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCochrane Database of Systematic Reviews6.754info:eu-repo/semantics/openAccess2024-08-16T18:44:44Zoai:repositorio.unesp.br:11449/112286Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T18:44:44Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants |
title |
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants |
spellingShingle |
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants Jorge, Eliane Chaves [UNESP] Lighting Infant, Newborn Infant, Premature Infant, Very Low Birth Weight Randomized Controlled Trials as Topic Retinopathy of Prematurity [prevention & control] Humans |
title_short |
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants |
title_full |
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants |
title_fullStr |
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants |
title_full_unstemmed |
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants |
title_sort |
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants |
author |
Jorge, Eliane Chaves [UNESP] |
author_facet |
Jorge, Eliane Chaves [UNESP] Jorge, Edson Nacib [UNESP] Dib, Regina Paolucci El [UNESP] |
author_role |
author |
author2 |
Jorge, Edson Nacib [UNESP] Dib, Regina Paolucci El [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Jorge, Eliane Chaves [UNESP] Jorge, Edson Nacib [UNESP] Dib, Regina Paolucci El [UNESP] |
dc.subject.por.fl_str_mv |
Lighting Infant, Newborn Infant, Premature Infant, Very Low Birth Weight Randomized Controlled Trials as Topic Retinopathy of Prematurity [prevention & control] Humans |
topic |
Lighting Infant, Newborn Infant, Premature Infant, Very Low Birth Weight Randomized Controlled Trials as Topic Retinopathy of Prematurity [prevention & control] Humans |
description |
BackgroundRetinopathy of prematurity (ROP) is a complex condition of the developing retinal blood vessels and is one of the leading causes of preventable childhood blindness. Several risk factors for ROP have been studied over the past 50 years. Among them, general immaturity (low birth weight and low gestational age) and prolonged oxygen therapy have been consistently related to disease onset. However, it is understood that the progression of the disease is multifactorial and may be associated with others risk factors, such as multiple gestation, apnoea, intracranial haemorrhage, anaemia, sepsis, prolonged mechanical ventilation, multiple transfusions and light exposure. Furthermore, the precise role of these individual factors in the development of the disease has not yet been well established.ObjectivesTo determine whether the reduction of early environmental light exposure reduces the incidence of retinopathy of prematurity (ROP) or poor ROP outcomes among very low birth weight infants.Search methodsWe searched the following databases: the Cochrane Neonatal Group Specialised Register, CENTRAL (The Cochrane Library), MEDLINE, EMBASE, CINAHL, HealthSTAR, Science Citation Index Database, CANCERLIT, the Oxford Database of Perinatal Trials and www.clinicaltrials.gov. We also searched previous reviews including cross-references, abstracts, conference and symposia proceedings, and contacted expert informants. This search was updated in October 2012.Selection criteriaRandomised or quasi-randomised controlled trials that reduced light exposure to premature infants within the first seven days following birth were considered for this review. We also considered cluster-randomised controlled trials.Data collection and analysisData on clinical outcomes including any acute ROP and poor ROP outcome were extracted by both review authors independently and consensus reached. We conducted data analysis according to the standards of the Cochrane Neonatal Review Group.Main resultsData from four randomised trials with a total of 897 participants failed to show any reduction in acute ROP or poor ROP outcome with the reduction of ambient light to premature infants' retinas. The overall methodological quality of the included studies was about evenly split between those in which the classification was unclear and those in which the studies were categorised as low risk of bias. There was no report on the secondary outcomes considered in this review: quality of life measures; and time of exposure to oxygen.Authors' conclusionsThe evidence shows that bright light is not the cause of retinopathy of prematurity and that the reduction of exposure of the retinas of premature infants to light has no effect on the incidence of the disease. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-01 2014-12-03T13:10:35Z 2014-12-03T13:10:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1002/14651858.CD000122.pub2 Cochrane Database Of Systematic Reviews. Hoboken: Wiley-blackwell, n. 8, 31 p., 2013. 1469-493X http://hdl.handle.net/11449/112286 10.1002/14651858.CD000122.pub2 WOS:000323928600002 0260120486355934 6692227903300380 0000-0003-3121-440X 0000-0002-4081-803X 0000-0002-9362-1505 |
url |
http://dx.doi.org/10.1002/14651858.CD000122.pub2 http://hdl.handle.net/11449/112286 |
identifier_str_mv |
Cochrane Database Of Systematic Reviews. Hoboken: Wiley-blackwell, n. 8, 31 p., 2013. 1469-493X 10.1002/14651858.CD000122.pub2 WOS:000323928600002 0260120486355934 6692227903300380 0000-0003-3121-440X 0000-0002-4081-803X 0000-0002-9362-1505 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Cochrane Database of Systematic Reviews 6.754 |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
31 |
dc.publisher.none.fl_str_mv |
Wiley-Blackwell |
publisher.none.fl_str_mv |
Wiley-Blackwell |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
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UNESP |
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UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128210480660480 |