Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment

Detalhes bibliográficos
Autor(a) principal: Chagas, Marcos Hortes N.
Data de Publicação: 2014
Outros Autores: Moriyama, Tais Silveira [UNIFESP], Felício, André Carvalho [UNIFESP], Sosa, Ana Luisa, Bressan, Rodrigo Affonseca [UNIFESP], Ferri, Cleusa Pinheiro [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
dARK ID: ark:/48912/0013000008pmr
DOI: 10.1590/0004-282X20140049
Texto Completo: http://dx.doi.org/10.1590/0004-282X20140049
http://repositorio.unifesp.br/handle/11600/8399
Resumo: Objective : To test the hypothesis that severity of cognitive impairment modifies the association between depression and Parkinson’s disease (PD). Method : One-phase population-based door-to-door surveys. This is a secondary analysis of 1,451 people aged 65 years and older with cognitive impairment living in defined catchment areas. Depression was estimated according to ICD-10, self-reported PD, disability according to WHODAS-II and cognitive status according to the CSI-D. Results : The mean age of the sample was 79.3 years old and most (69%) were women. Of the total sample, 16.1% had depression and it was significantly higher among participants with PD. There was an increase on the ORs of the association between depression and PD with decreased scores in the cognitive test (Adjusted OR from 0.98 to 8.04). Conclusion : The association between depression and PD increases with the severity of the cognitive impairment.
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spelling Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairmentEm pacientes com doença de Parkinson, a depressão aumenta de acordo com o aumento da gravidade do comprometimento cognitivoparkinsonismdepressioncognitive impairmentParkinson?s diseaseparkinsonismodepressãoprejuízo cognitivodoença de ParkinsonObjective : To test the hypothesis that severity of cognitive impairment modifies the association between depression and Parkinson’s disease (PD). Method : One-phase population-based door-to-door surveys. This is a secondary analysis of 1,451 people aged 65 years and older with cognitive impairment living in defined catchment areas. Depression was estimated according to ICD-10, self-reported PD, disability according to WHODAS-II and cognitive status according to the CSI-D. Results : The mean age of the sample was 79.3 years old and most (69%) were women. Of the total sample, 16.1% had depression and it was significantly higher among participants with PD. There was an increase on the ORs of the association between depression and PD with decreased scores in the cognitive test (Adjusted OR from 0.98 to 8.04). Conclusion : The association between depression and PD increases with the severity of the cognitive impairment.Objetivo : Testar a hipótese que a gravidade do prejuízo cognitivo modifica a associação entre depressão e doença de Parkinson (DP). Método : Estudo populacional através da análise secundária de 1.451 pessoas com idade maior ou igual a 65 anos com prejuízo cognitivo que residiam em áreas de abrangência definidas. A depressão foi estimada de acordo com a CID-10, auto-relato de DP, incapacidade conforme a WHODAS-II e nível cognitvo de acordo com a CSI-D. Resultado : A média de idade foi 79,3 anos, predominaram as mulheres (69%). Do total de indivíduos, 16,1% tinham depressão, significantemente maior entre os participantes com DP. Houve aumento gradativo na OR relativa à associação entre depressão e DP com a diminuição do escore no teste cognitivo (OR ajustado variou de 0,98 a 8,04). Conclusão : A associação entre depressão e DP parece aumentar com a gravidade do prejuízo cognitivo.Universidade de São Paulo Departamento de Neurociências e Ciências do ComportamentoUniversidade Federal de São Paulo (UNIFESP) Laboratório Interdisciplinar de Neurociências Clínicas Departamento de PsiquiatriaHospital Israelita Albert Einstein Instituto Israelita de Ensino e PesquisaNational Institute of Neurology and Neurosurgery of MéxicoUniversidade Federal de São Paulo (UNIFESP) Departamento de PsicobiologiaUNIFESP, Laboratório Interdisciplinar de Neurociências Clínicas Depto. de PsiquiatriaUNIFESP, Depto. de PsicobiologiaSciELOAcademia Brasileira de Neurologia - ABNEUROUniversidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)Hospital Israelita Albert Einstein Instituto Israelita de Ensino e PesquisaNational Institute of Neurology and Neurosurgery of MéxicoChagas, Marcos Hortes N.Moriyama, Tais Silveira [UNIFESP]Felício, André Carvalho [UNIFESP]Sosa, Ana LuisaBressan, Rodrigo Affonseca [UNIFESP]Ferri, Cleusa Pinheiro [UNIFESP]2015-06-14T13:47:07Z2015-06-14T13:47:07Z2014-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion426-429application/pdfhttp://dx.doi.org/10.1590/0004-282X20140049Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 72, n. 6, p. 426-429, 2014.10.1590/0004-282X20140049S0004-282X2014000600426.pdf0004-282XS0004-282X2014000600426http://repositorio.unifesp.br/handle/11600/8399ark:/48912/0013000008pmrengArquivos de Neuro-Psiquiatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T12:48:21Zoai:repositorio.unifesp.br/:11600/8399Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:05:29.902346Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
Em pacientes com doença de Parkinson, a depressão aumenta de acordo com o aumento da gravidade do comprometimento cognitivo
title Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
spellingShingle Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
Chagas, Marcos Hortes N.
parkinsonism
depression
cognitive impairment
Parkinson?s disease
parkinsonismo
depressão
prejuízo cognitivo
doença de Parkinson
Chagas, Marcos Hortes N.
parkinsonism
depression
cognitive impairment
Parkinson?s disease
parkinsonismo
depressão
prejuízo cognitivo
doença de Parkinson
title_short Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
title_full Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
title_fullStr Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
title_full_unstemmed Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
title_sort Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment
author Chagas, Marcos Hortes N.
author_facet Chagas, Marcos Hortes N.
Chagas, Marcos Hortes N.
Moriyama, Tais Silveira [UNIFESP]
Felício, André Carvalho [UNIFESP]
Sosa, Ana Luisa
Bressan, Rodrigo Affonseca [UNIFESP]
Ferri, Cleusa Pinheiro [UNIFESP]
Moriyama, Tais Silveira [UNIFESP]
Felício, André Carvalho [UNIFESP]
Sosa, Ana Luisa
Bressan, Rodrigo Affonseca [UNIFESP]
Ferri, Cleusa Pinheiro [UNIFESP]
author_role author
author2 Moriyama, Tais Silveira [UNIFESP]
Felício, André Carvalho [UNIFESP]
Sosa, Ana Luisa
Bressan, Rodrigo Affonseca [UNIFESP]
Ferri, Cleusa Pinheiro [UNIFESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Hospital Israelita Albert Einstein Instituto Israelita de Ensino e Pesquisa
National Institute of Neurology and Neurosurgery of México
dc.contributor.author.fl_str_mv Chagas, Marcos Hortes N.
Moriyama, Tais Silveira [UNIFESP]
Felício, André Carvalho [UNIFESP]
Sosa, Ana Luisa
Bressan, Rodrigo Affonseca [UNIFESP]
Ferri, Cleusa Pinheiro [UNIFESP]
dc.subject.por.fl_str_mv parkinsonism
depression
cognitive impairment
Parkinson?s disease
parkinsonismo
depressão
prejuízo cognitivo
doença de Parkinson
topic parkinsonism
depression
cognitive impairment
Parkinson?s disease
parkinsonismo
depressão
prejuízo cognitivo
doença de Parkinson
description Objective : To test the hypothesis that severity of cognitive impairment modifies the association between depression and Parkinson’s disease (PD). Method : One-phase population-based door-to-door surveys. This is a secondary analysis of 1,451 people aged 65 years and older with cognitive impairment living in defined catchment areas. Depression was estimated according to ICD-10, self-reported PD, disability according to WHODAS-II and cognitive status according to the CSI-D. Results : The mean age of the sample was 79.3 years old and most (69%) were women. Of the total sample, 16.1% had depression and it was significantly higher among participants with PD. There was an increase on the ORs of the association between depression and PD with decreased scores in the cognitive test (Adjusted OR from 0.98 to 8.04). Conclusion : The association between depression and PD increases with the severity of the cognitive impairment.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-01
2015-06-14T13:47:07Z
2015-06-14T13:47:07Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/0004-282X20140049
Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 72, n. 6, p. 426-429, 2014.
10.1590/0004-282X20140049
S0004-282X2014000600426.pdf
0004-282X
S0004-282X2014000600426
http://repositorio.unifesp.br/handle/11600/8399
dc.identifier.dark.fl_str_mv ark:/48912/0013000008pmr
url http://dx.doi.org/10.1590/0004-282X20140049
http://repositorio.unifesp.br/handle/11600/8399
identifier_str_mv Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 72, n. 6, p. 426-429, 2014.
10.1590/0004-282X20140049
S0004-282X2014000600426.pdf
0004-282X
S0004-282X2014000600426
ark:/48912/0013000008pmr
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos de Neuro-Psiquiatria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 426-429
application/pdf
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1822183947282415616
dc.identifier.doi.none.fl_str_mv 10.1590/0004-282X20140049

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