Estudo ultraestrutural do colo uterino de ratas ooforectomizadas após aplicação de óleo de copaíba

• Autor(a) principal: Botelho, Nara Macedo [UNIFESP]
• Data de Publicação: 2000
• Outros Autores: Kulay-Júnior, Luiz [UNIFESP], Simões, Manuel de Jesus [UNIFESP], Mora, Oswaldo Alves [UNIFESP], Diniz, José Antonio Picanço, Lamarão, Luciana Garcia
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0102-86502000000400003; http://repositorio.unifesp.br/handle/11600/1056
• topic: Rats; Cervix uteri; Ovariectomy; Ratos; Colo uterino; Ovariectomia

In Amazônia there are a lot of plants used alternatively for diseases. The copaíba oil, extract from a tree called Copaifera, has shown great importance in this context. By vaginal route is apllied for therapeutic of cervicitis and leucohrrea. Because of the large empirically employment of this oil in gynecological treatment, the present study objective to study ultraestruturally the effect of this substance in the rats uterus colo. It was used 12 females rats, adults, distributed in four groups: copaíba oil, corn oil, water and control. All the animals were submitted to bilateral oophorectomy and after twenty days began the substances application. The animals were killed in pre-determined time periods (7, 14 and 21 days). The corn oil, water and control groups showed epithelium with two or three cells filers and copaíba group showed epithelium with eight or tem. It was concluded that copaíba oil promoted an increase in the number of epithelial cells with queratinization in the oophorectomized rats.