Classification and hearing evolution of patients with sudden sensorineural hearing loss

Detalhes bibliográficos
Autor(a) principal: Penido, Norma de Oliveira [UNIFESP]
Data de Publicação: 2009
Outros Autores: Cruz, Oswaldo Laércio Mendonça [UNIFESP], Zanoni, A. [UNIFESP], Inoue, Daniel Paganini [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0100-879X2009000800004
http://repositorio.unifesp.br/handle/11600/5178
Resumo: The aim of this study was to analyze clinical aspects, hearing evolution and efficacy of clinical treatment of patients with sudden sensorineural hearing loss (SSNHL). This was a prospective clinical study of 136 consecutive patients with SSNHL divided into three groups after diagnostic evaluation: patients with defined etiology (DE, N = 13, 10%), concurrent diseases (CD, N = 63, 46.04%) and idiopathic sudden sensorineural hearing loss (ISSHL, N = 60, 43.9%). Initial treatment consisted of prednisone and pentoxifylline. Clinical aspects and hearing evolution for up to 6 months were evaluated. Group CD comprised 73% of patients with metabolic decompensation in the initial evaluation and was significantly older (53.80 years) than groups DE (41.93 years) and ISSHL (39.13 years). Comparison of the mean initial and final hearing loss of the three groups revealed a significant hearing improvement for group CD (P = 0.001) and group ISSHL (P = 0.001). Group DE did not present a significant difference in thresholds. The clinical classification for SSNHL allows the identification of significant differences regarding age, initial and final hearing impairment and likelihood of response to therapy. Elevated age and presence of coexisting disease were associated with a greater initial hearing impact and poorer hearing recovery after 6 months. Patients with defined etiology presented a much more limited response to therapy. The occurrence of decompensated metabolic and cardiovascular diseases and the possibility of first manifestation of auto-immune disease and cerebello-pontine angle tumors justify an adequate protocol for investigation of SSNHL.
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spelling Classification and hearing evolution of patients with sudden sensorineural hearing lossSensorineural hearing lossSudden deafnessPrognosisThe aim of this study was to analyze clinical aspects, hearing evolution and efficacy of clinical treatment of patients with sudden sensorineural hearing loss (SSNHL). This was a prospective clinical study of 136 consecutive patients with SSNHL divided into three groups after diagnostic evaluation: patients with defined etiology (DE, N = 13, 10%), concurrent diseases (CD, N = 63, 46.04%) and idiopathic sudden sensorineural hearing loss (ISSHL, N = 60, 43.9%). Initial treatment consisted of prednisone and pentoxifylline. Clinical aspects and hearing evolution for up to 6 months were evaluated. Group CD comprised 73% of patients with metabolic decompensation in the initial evaluation and was significantly older (53.80 years) than groups DE (41.93 years) and ISSHL (39.13 years). Comparison of the mean initial and final hearing loss of the three groups revealed a significant hearing improvement for group CD (P = 0.001) and group ISSHL (P = 0.001). Group DE did not present a significant difference in thresholds. The clinical classification for SSNHL allows the identification of significant differences regarding age, initial and final hearing impairment and likelihood of response to therapy. Elevated age and presence of coexisting disease were associated with a greater initial hearing impact and poorer hearing recovery after 6 months. Patients with defined etiology presented a much more limited response to therapy. The occurrence of decompensated metabolic and cardiovascular diseases and the possibility of first manifestation of auto-immune disease and cerebello-pontine angle tumors justify an adequate protocol for investigation of SSNHL.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Otorrinolaringologia e Cirurgia de Cabeça e PescoçoUNIFESP, EPM, Depto. de Otorrinolaringologia e Cirurgia de Cabeça e PescoçoSciELOAssociação Brasileira de Divulgação CientíficaUniversidade Federal de São Paulo (UNIFESP)Penido, Norma de Oliveira [UNIFESP]Cruz, Oswaldo Laércio Mendonça [UNIFESP]Zanoni, A. [UNIFESP]Inoue, Daniel Paganini [UNIFESP]2015-06-14T13:41:05Z2015-06-14T13:41:05Z2009-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion712-716application/pdfhttp://dx.doi.org/10.1590/S0100-879X2009000800004Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 42, n. 8, p. 712-716, 2009.10.1590/S0100-879X2009000800004S0100-879X2009000800004.pdf0100-879XS0100-879X2009000800004http://repositorio.unifesp.br/handle/11600/5178WOS:000269123000004engBrazilian Journal of Medical and Biological Researchinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T18:15:39Zoai:repositorio.unifesp.br/:11600/5178Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T18:15:39Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Classification and hearing evolution of patients with sudden sensorineural hearing loss
title Classification and hearing evolution of patients with sudden sensorineural hearing loss
spellingShingle Classification and hearing evolution of patients with sudden sensorineural hearing loss
Penido, Norma de Oliveira [UNIFESP]
Sensorineural hearing loss
Sudden deafness
Prognosis
title_short Classification and hearing evolution of patients with sudden sensorineural hearing loss
title_full Classification and hearing evolution of patients with sudden sensorineural hearing loss
title_fullStr Classification and hearing evolution of patients with sudden sensorineural hearing loss
title_full_unstemmed Classification and hearing evolution of patients with sudden sensorineural hearing loss
title_sort Classification and hearing evolution of patients with sudden sensorineural hearing loss
author Penido, Norma de Oliveira [UNIFESP]
author_facet Penido, Norma de Oliveira [UNIFESP]
Cruz, Oswaldo Laércio Mendonça [UNIFESP]
Zanoni, A. [UNIFESP]
Inoue, Daniel Paganini [UNIFESP]
author_role author
author2 Cruz, Oswaldo Laércio Mendonça [UNIFESP]
Zanoni, A. [UNIFESP]
Inoue, Daniel Paganini [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Penido, Norma de Oliveira [UNIFESP]
Cruz, Oswaldo Laércio Mendonça [UNIFESP]
Zanoni, A. [UNIFESP]
Inoue, Daniel Paganini [UNIFESP]
dc.subject.por.fl_str_mv Sensorineural hearing loss
Sudden deafness
Prognosis
topic Sensorineural hearing loss
Sudden deafness
Prognosis
description The aim of this study was to analyze clinical aspects, hearing evolution and efficacy of clinical treatment of patients with sudden sensorineural hearing loss (SSNHL). This was a prospective clinical study of 136 consecutive patients with SSNHL divided into three groups after diagnostic evaluation: patients with defined etiology (DE, N = 13, 10%), concurrent diseases (CD, N = 63, 46.04%) and idiopathic sudden sensorineural hearing loss (ISSHL, N = 60, 43.9%). Initial treatment consisted of prednisone and pentoxifylline. Clinical aspects and hearing evolution for up to 6 months were evaluated. Group CD comprised 73% of patients with metabolic decompensation in the initial evaluation and was significantly older (53.80 years) than groups DE (41.93 years) and ISSHL (39.13 years). Comparison of the mean initial and final hearing loss of the three groups revealed a significant hearing improvement for group CD (P = 0.001) and group ISSHL (P = 0.001). Group DE did not present a significant difference in thresholds. The clinical classification for SSNHL allows the identification of significant differences regarding age, initial and final hearing impairment and likelihood of response to therapy. Elevated age and presence of coexisting disease were associated with a greater initial hearing impact and poorer hearing recovery after 6 months. Patients with defined etiology presented a much more limited response to therapy. The occurrence of decompensated metabolic and cardiovascular diseases and the possibility of first manifestation of auto-immune disease and cerebello-pontine angle tumors justify an adequate protocol for investigation of SSNHL.
publishDate 2009
dc.date.none.fl_str_mv 2009-08-01
2015-06-14T13:41:05Z
2015-06-14T13:41:05Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0100-879X2009000800004
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 42, n. 8, p. 712-716, 2009.
10.1590/S0100-879X2009000800004
S0100-879X2009000800004.pdf
0100-879X
S0100-879X2009000800004
http://repositorio.unifesp.br/handle/11600/5178
WOS:000269123000004
url http://dx.doi.org/10.1590/S0100-879X2009000800004
http://repositorio.unifesp.br/handle/11600/5178
identifier_str_mv Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 42, n. 8, p. 712-716, 2009.
10.1590/S0100-879X2009000800004
S0100-879X2009000800004.pdf
0100-879X
S0100-879X2009000800004
WOS:000269123000004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Medical and Biological Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 712-716
application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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