Classification and hearing evolution of patients with sudden sensorineural hearing loss
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S0100-879X2009000800004 http://repositorio.unifesp.br/handle/11600/5178 |
Resumo: | The aim of this study was to analyze clinical aspects, hearing evolution and efficacy of clinical treatment of patients with sudden sensorineural hearing loss (SSNHL). This was a prospective clinical study of 136 consecutive patients with SSNHL divided into three groups after diagnostic evaluation: patients with defined etiology (DE, N = 13, 10%), concurrent diseases (CD, N = 63, 46.04%) and idiopathic sudden sensorineural hearing loss (ISSHL, N = 60, 43.9%). Initial treatment consisted of prednisone and pentoxifylline. Clinical aspects and hearing evolution for up to 6 months were evaluated. Group CD comprised 73% of patients with metabolic decompensation in the initial evaluation and was significantly older (53.80 years) than groups DE (41.93 years) and ISSHL (39.13 years). Comparison of the mean initial and final hearing loss of the three groups revealed a significant hearing improvement for group CD (P = 0.001) and group ISSHL (P = 0.001). Group DE did not present a significant difference in thresholds. The clinical classification for SSNHL allows the identification of significant differences regarding age, initial and final hearing impairment and likelihood of response to therapy. Elevated age and presence of coexisting disease were associated with a greater initial hearing impact and poorer hearing recovery after 6 months. Patients with defined etiology presented a much more limited response to therapy. The occurrence of decompensated metabolic and cardiovascular diseases and the possibility of first manifestation of auto-immune disease and cerebello-pontine angle tumors justify an adequate protocol for investigation of SSNHL. |
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Classification and hearing evolution of patients with sudden sensorineural hearing lossSensorineural hearing lossSudden deafnessPrognosisThe aim of this study was to analyze clinical aspects, hearing evolution and efficacy of clinical treatment of patients with sudden sensorineural hearing loss (SSNHL). This was a prospective clinical study of 136 consecutive patients with SSNHL divided into three groups after diagnostic evaluation: patients with defined etiology (DE, N = 13, 10%), concurrent diseases (CD, N = 63, 46.04%) and idiopathic sudden sensorineural hearing loss (ISSHL, N = 60, 43.9%). Initial treatment consisted of prednisone and pentoxifylline. Clinical aspects and hearing evolution for up to 6 months were evaluated. Group CD comprised 73% of patients with metabolic decompensation in the initial evaluation and was significantly older (53.80 years) than groups DE (41.93 years) and ISSHL (39.13 years). Comparison of the mean initial and final hearing loss of the three groups revealed a significant hearing improvement for group CD (P = 0.001) and group ISSHL (P = 0.001). Group DE did not present a significant difference in thresholds. The clinical classification for SSNHL allows the identification of significant differences regarding age, initial and final hearing impairment and likelihood of response to therapy. Elevated age and presence of coexisting disease were associated with a greater initial hearing impact and poorer hearing recovery after 6 months. Patients with defined etiology presented a much more limited response to therapy. The occurrence of decompensated metabolic and cardiovascular diseases and the possibility of first manifestation of auto-immune disease and cerebello-pontine angle tumors justify an adequate protocol for investigation of SSNHL.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Otorrinolaringologia e Cirurgia de Cabeça e PescoçoUNIFESP, EPM, Depto. de Otorrinolaringologia e Cirurgia de Cabeça e PescoçoSciELOAssociação Brasileira de Divulgação CientíficaUniversidade Federal de São Paulo (UNIFESP)Penido, Norma de Oliveira [UNIFESP]Cruz, Oswaldo Laércio Mendonça [UNIFESP]Zanoni, A. [UNIFESP]Inoue, Daniel Paganini [UNIFESP]2015-06-14T13:41:05Z2015-06-14T13:41:05Z2009-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion712-716application/pdfhttp://dx.doi.org/10.1590/S0100-879X2009000800004Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 42, n. 8, p. 712-716, 2009.10.1590/S0100-879X2009000800004S0100-879X2009000800004.pdf0100-879XS0100-879X2009000800004http://repositorio.unifesp.br/handle/11600/5178WOS:000269123000004engBrazilian Journal of Medical and Biological Researchinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T18:15:39Zoai:repositorio.unifesp.br/:11600/5178Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T18:15:39Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Classification and hearing evolution of patients with sudden sensorineural hearing loss |
title |
Classification and hearing evolution of patients with sudden sensorineural hearing loss |
spellingShingle |
Classification and hearing evolution of patients with sudden sensorineural hearing loss Penido, Norma de Oliveira [UNIFESP] Sensorineural hearing loss Sudden deafness Prognosis |
title_short |
Classification and hearing evolution of patients with sudden sensorineural hearing loss |
title_full |
Classification and hearing evolution of patients with sudden sensorineural hearing loss |
title_fullStr |
Classification and hearing evolution of patients with sudden sensorineural hearing loss |
title_full_unstemmed |
Classification and hearing evolution of patients with sudden sensorineural hearing loss |
title_sort |
Classification and hearing evolution of patients with sudden sensorineural hearing loss |
author |
Penido, Norma de Oliveira [UNIFESP] |
author_facet |
Penido, Norma de Oliveira [UNIFESP] Cruz, Oswaldo Laércio Mendonça [UNIFESP] Zanoni, A. [UNIFESP] Inoue, Daniel Paganini [UNIFESP] |
author_role |
author |
author2 |
Cruz, Oswaldo Laércio Mendonça [UNIFESP] Zanoni, A. [UNIFESP] Inoue, Daniel Paganini [UNIFESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Penido, Norma de Oliveira [UNIFESP] Cruz, Oswaldo Laércio Mendonça [UNIFESP] Zanoni, A. [UNIFESP] Inoue, Daniel Paganini [UNIFESP] |
dc.subject.por.fl_str_mv |
Sensorineural hearing loss Sudden deafness Prognosis |
topic |
Sensorineural hearing loss Sudden deafness Prognosis |
description |
The aim of this study was to analyze clinical aspects, hearing evolution and efficacy of clinical treatment of patients with sudden sensorineural hearing loss (SSNHL). This was a prospective clinical study of 136 consecutive patients with SSNHL divided into three groups after diagnostic evaluation: patients with defined etiology (DE, N = 13, 10%), concurrent diseases (CD, N = 63, 46.04%) and idiopathic sudden sensorineural hearing loss (ISSHL, N = 60, 43.9%). Initial treatment consisted of prednisone and pentoxifylline. Clinical aspects and hearing evolution for up to 6 months were evaluated. Group CD comprised 73% of patients with metabolic decompensation in the initial evaluation and was significantly older (53.80 years) than groups DE (41.93 years) and ISSHL (39.13 years). Comparison of the mean initial and final hearing loss of the three groups revealed a significant hearing improvement for group CD (P = 0.001) and group ISSHL (P = 0.001). Group DE did not present a significant difference in thresholds. The clinical classification for SSNHL allows the identification of significant differences regarding age, initial and final hearing impairment and likelihood of response to therapy. Elevated age and presence of coexisting disease were associated with a greater initial hearing impact and poorer hearing recovery after 6 months. Patients with defined etiology presented a much more limited response to therapy. The occurrence of decompensated metabolic and cardiovascular diseases and the possibility of first manifestation of auto-immune disease and cerebello-pontine angle tumors justify an adequate protocol for investigation of SSNHL. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-08-01 2015-06-14T13:41:05Z 2015-06-14T13:41:05Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0100-879X2009000800004 Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 42, n. 8, p. 712-716, 2009. 10.1590/S0100-879X2009000800004 S0100-879X2009000800004.pdf 0100-879X S0100-879X2009000800004 http://repositorio.unifesp.br/handle/11600/5178 WOS:000269123000004 |
url |
http://dx.doi.org/10.1590/S0100-879X2009000800004 http://repositorio.unifesp.br/handle/11600/5178 |
identifier_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 42, n. 8, p. 712-716, 2009. 10.1590/S0100-879X2009000800004 S0100-879X2009000800004.pdf 0100-879X S0100-879X2009000800004 WOS:000269123000004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
712-716 application/pdf |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268447106793472 |