Experimental model to study the effect of nicotine in a random skin flap, in the rat

Detalhes bibliográficos
Autor(a) principal: Gomes, Heitor Carvalho [UNIFESP]
Data de Publicação: 2004
Outros Autores: Campos, José Humberto Oliveira, Ferreira, Lydia Masako [UNIFESP], Kobayashi, Ludmila Aimi [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0102-86502004000700012
http://repositorio.unifesp.br/handle/11600/2303
Resumo: Presentation of an experimental model to study the effect of nicotine in a random skin flap, in the rat. Adult rats of the same lineage are exposed to nicotine for seven days in the preoperative period. After the preoperative period, the animals are anesthetized and a dorsal random pattern skin flap, cranially based is elevated. On the seventh postoperative day, the rats are anesthetized and the percentages of distal necrosis in the flaps are determined. After that, excision of skin fragments for biochemical analysis is possible. Blood samples may be collected by decapitation.
id UFSP_9bdf03330bbd9cab010ae050edfc8b59
oai_identifier_str oai:repositorio.unifesp.br/:11600/2303
network_acronym_str UFSP
network_name_str Repositório Institucional da UNIFESP
repository_id_str 3465
spelling Experimental model to study the effect of nicotine in a random skin flap, in the ratModelo experimental para o estudo do efeito da nicotina em retalho cutâneo randômico, no ratoSurgical flapsNicotineTobaccoRatsRetalhos cirúrgicosNicotinaTabacoRatosPresentation of an experimental model to study the effect of nicotine in a random skin flap, in the rat. Adult rats of the same lineage are exposed to nicotine for seven days in the preoperative period. After the preoperative period, the animals are anesthetized and a dorsal random pattern skin flap, cranially based is elevated. On the seventh postoperative day, the rats are anesthetized and the percentages of distal necrosis in the flaps are determined. After that, excision of skin fragments for biochemical analysis is possible. Blood samples may be collected by decapitation.Apresentação de um modelo experimental para estudar o efeito da nicotina em um retalho cutâneo randômico, no rato. Ratos adultos da mesma linhagem são expostos à nicotina por sete dias no período pré-operatório. Após este período os animais são anestesiados e um retalho cutâneo randômico dorsal, de base cranial é elevado. No sétimo dia de pós-operatório, os ratos são anestesiados e as porcentagens de necrose distal são determinadas. Isto feito, é possível colher fragmentos de pele para análise bioquímica. Amostras de sangue podem ser colhidas por decapitação.Federal University of São Paulo EPMMedicine School of BahiaFederal University of São Paulo EPM Surgery DepartmentUNIFESP, EPM, Surgery DepartmentSciELOSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaUniversidade Federal de São Paulo (UNIFESP)Medicine School of BahiaGomes, Heitor Carvalho [UNIFESP]Campos, José Humberto OliveiraFerreira, Lydia Masako [UNIFESP]Kobayashi, Ludmila Aimi [UNIFESP]2015-06-14T13:31:21Z2015-06-14T13:31:21Z2004-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion65-68application/pdfhttp://dx.doi.org/10.1590/S0102-86502004000700012Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 19, p. 65-68, 2004.10.1590/S0102-86502004000700012S0102-86502004000700012.pdf0102-8650S0102-86502004000700012http://repositorio.unifesp.br/handle/11600/2303engActa Cirurgica Brasileirainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-28T08:33:36Zoai:repositorio.unifesp.br/:11600/2303Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-28T08:33:36Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Experimental model to study the effect of nicotine in a random skin flap, in the rat
Modelo experimental para o estudo do efeito da nicotina em retalho cutâneo randômico, no rato
title Experimental model to study the effect of nicotine in a random skin flap, in the rat
spellingShingle Experimental model to study the effect of nicotine in a random skin flap, in the rat
Gomes, Heitor Carvalho [UNIFESP]
Surgical flaps
Nicotine
Tobacco
Rats
Retalhos cirúrgicos
Nicotina
Tabaco
Ratos
title_short Experimental model to study the effect of nicotine in a random skin flap, in the rat
title_full Experimental model to study the effect of nicotine in a random skin flap, in the rat
title_fullStr Experimental model to study the effect of nicotine in a random skin flap, in the rat
title_full_unstemmed Experimental model to study the effect of nicotine in a random skin flap, in the rat
title_sort Experimental model to study the effect of nicotine in a random skin flap, in the rat
author Gomes, Heitor Carvalho [UNIFESP]
author_facet Gomes, Heitor Carvalho [UNIFESP]
Campos, José Humberto Oliveira
Ferreira, Lydia Masako [UNIFESP]
Kobayashi, Ludmila Aimi [UNIFESP]
author_role author
author2 Campos, José Humberto Oliveira
Ferreira, Lydia Masako [UNIFESP]
Kobayashi, Ludmila Aimi [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Medicine School of Bahia
dc.contributor.author.fl_str_mv Gomes, Heitor Carvalho [UNIFESP]
Campos, José Humberto Oliveira
Ferreira, Lydia Masako [UNIFESP]
Kobayashi, Ludmila Aimi [UNIFESP]
dc.subject.por.fl_str_mv Surgical flaps
Nicotine
Tobacco
Rats
Retalhos cirúrgicos
Nicotina
Tabaco
Ratos
topic Surgical flaps
Nicotine
Tobacco
Rats
Retalhos cirúrgicos
Nicotina
Tabaco
Ratos
description Presentation of an experimental model to study the effect of nicotine in a random skin flap, in the rat. Adult rats of the same lineage are exposed to nicotine for seven days in the preoperative period. After the preoperative period, the animals are anesthetized and a dorsal random pattern skin flap, cranially based is elevated. On the seventh postoperative day, the rats are anesthetized and the percentages of distal necrosis in the flaps are determined. After that, excision of skin fragments for biochemical analysis is possible. Blood samples may be collected by decapitation.
publishDate 2004
dc.date.none.fl_str_mv 2004-12-01
2015-06-14T13:31:21Z
2015-06-14T13:31:21Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0102-86502004000700012
Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 19, p. 65-68, 2004.
10.1590/S0102-86502004000700012
S0102-86502004000700012.pdf
0102-8650
S0102-86502004000700012
http://repositorio.unifesp.br/handle/11600/2303
url http://dx.doi.org/10.1590/S0102-86502004000700012
http://repositorio.unifesp.br/handle/11600/2303
identifier_str_mv Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 19, p. 65-68, 2004.
10.1590/S0102-86502004000700012
S0102-86502004000700012.pdf
0102-8650
S0102-86502004000700012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Cirurgica Brasileira
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 65-68
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268411755102208

Registros relacionados