The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?

Detalhes bibliográficos
Autor(a) principal: Albuquerque, Marly de [UNIFESP]
Data de Publicação: 2009
Outros Autores: Scorza, Carla Alessandra [UNIFESP], Arida, Ricardo Mario [UNIFESP], Cavalheiro, Esper Abrão [UNIFESP], Scorza, Fulvio Alexandre [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0004-282X2009000300038
http://repositorio.unifesp.br/handle/11600/5020
Resumo: Epilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but high seizure frequency is a potential risk factor. Additionally, potential pathomechanisms for SUDEP are unknown, but it is very probable that cardiac arrhythmias during and between seizures or transmission of epileptic activity to the heart via the autonomic nervous system potentially play a role. More than two decades ago, temporal lobe epilepsy was suggested as having been the ''nervous disease'' of Gustave Flaubert, one of the most important French novelists. In these lines, as the circumstances of his death were the subject of fabulous and mysterious speculations, we postulated in this paper that Falubert' death could be due SUDEP phenomenon.
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spelling The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?O mistério da morte de Gustave Flaubert: pode a morte súbita em epilepsia fazer parte o contexto?epilepsyGustave FlaubertSUDEPseizureepilepsiaGustave FlaubertSUDEPcrise epilépticaEpilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but high seizure frequency is a potential risk factor. Additionally, potential pathomechanisms for SUDEP are unknown, but it is very probable that cardiac arrhythmias during and between seizures or transmission of epileptic activity to the heart via the autonomic nervous system potentially play a role. More than two decades ago, temporal lobe epilepsy was suggested as having been the ''nervous disease'' of Gustave Flaubert, one of the most important French novelists. In these lines, as the circumstances of his death were the subject of fabulous and mysterious speculations, we postulated in this paper that Falubert' death could be due SUDEP phenomenon.A epilepsia é a condição neurológica crônica grave mais comum e a morte súbita em epilepsia (SUDEP) é a mais importante causa de morte diretamente relacionada à epilepsia. Informações sobre fatores de risco para SUDEP são conflitantes, porém, a alta freqüência de crises epilépticas é um fator de risco em potencial. Além disso, os mecanismos causais para SUDEP ainda não estão conhecidos, mas é muito provável que arritmias cardíacas durante e entre as crises epilépticas ou a transmissão da atividade epiléptica para o coração via sistema nervoso autônomo desempenhem um importante papel. Mais de duas décadas atrás, foi proposto que a doença nervosa de Gustave Flaubert, um dos mais importantes novelistas franceses, era epilepsia do lobo temporal. Nesse sentido, como a morte de Gustave Flaubert ainda seja motivo de misteriosa especulação, nosso artigo propõe que a mesma poderia estar relacionada ao fenômeno de SUDEP.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de FisiologiaUNIFESP, EPM, Depto. de FisiologiaSciELOAcademia Brasileira de Neurologia - ABNEUROUniversidade Federal de São Paulo (UNIFESP)Albuquerque, Marly de [UNIFESP]Scorza, Carla Alessandra [UNIFESP]Arida, Ricardo Mario [UNIFESP]Cavalheiro, Esper Abrão [UNIFESP]Scorza, Fulvio Alexandre [UNIFESP]2015-06-14T13:39:12Z2015-06-14T13:39:12Z2009-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion548-552application/pdfhttp://dx.doi.org/10.1590/S0004-282X2009000300038Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 67, n. 2b, p. 548-552, 2009.10.1590/S0004-282X2009000300038S0004-282X2009000300038.pdf0004-282XS0004-282X2009000300038http://repositorio.unifesp.br/handle/11600/5020WOS:000268140200038engArquivos de Neuro-Psiquiatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T12:18:27Zoai:repositorio.unifesp.br/:11600/5020Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T12:18:27Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?
O mistério da morte de Gustave Flaubert: pode a morte súbita em epilepsia fazer parte o contexto?
title The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?
spellingShingle The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?
Albuquerque, Marly de [UNIFESP]
epilepsy
Gustave Flaubert
SUDEP
seizure
epilepsia
Gustave Flaubert
SUDEP
crise epiléptica
title_short The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?
title_full The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?
title_fullStr The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?
title_full_unstemmed The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?
title_sort The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?
author Albuquerque, Marly de [UNIFESP]
author_facet Albuquerque, Marly de [UNIFESP]
Scorza, Carla Alessandra [UNIFESP]
Arida, Ricardo Mario [UNIFESP]
Cavalheiro, Esper Abrão [UNIFESP]
Scorza, Fulvio Alexandre [UNIFESP]
author_role author
author2 Scorza, Carla Alessandra [UNIFESP]
Arida, Ricardo Mario [UNIFESP]
Cavalheiro, Esper Abrão [UNIFESP]
Scorza, Fulvio Alexandre [UNIFESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Albuquerque, Marly de [UNIFESP]
Scorza, Carla Alessandra [UNIFESP]
Arida, Ricardo Mario [UNIFESP]
Cavalheiro, Esper Abrão [UNIFESP]
Scorza, Fulvio Alexandre [UNIFESP]
dc.subject.por.fl_str_mv epilepsy
Gustave Flaubert
SUDEP
seizure
epilepsia
Gustave Flaubert
SUDEP
crise epiléptica
topic epilepsy
Gustave Flaubert
SUDEP
seizure
epilepsia
Gustave Flaubert
SUDEP
crise epiléptica
description Epilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but high seizure frequency is a potential risk factor. Additionally, potential pathomechanisms for SUDEP are unknown, but it is very probable that cardiac arrhythmias during and between seizures or transmission of epileptic activity to the heart via the autonomic nervous system potentially play a role. More than two decades ago, temporal lobe epilepsy was suggested as having been the ''nervous disease'' of Gustave Flaubert, one of the most important French novelists. In these lines, as the circumstances of his death were the subject of fabulous and mysterious speculations, we postulated in this paper that Falubert' death could be due SUDEP phenomenon.
publishDate 2009
dc.date.none.fl_str_mv 2009-06-01
2015-06-14T13:39:12Z
2015-06-14T13:39:12Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0004-282X2009000300038
Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 67, n. 2b, p. 548-552, 2009.
10.1590/S0004-282X2009000300038
S0004-282X2009000300038.pdf
0004-282X
S0004-282X2009000300038
http://repositorio.unifesp.br/handle/11600/5020
WOS:000268140200038
url http://dx.doi.org/10.1590/S0004-282X2009000300038
http://repositorio.unifesp.br/handle/11600/5020
identifier_str_mv Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 67, n. 2b, p. 548-552, 2009.
10.1590/S0004-282X2009000300038
S0004-282X2009000300038.pdf
0004-282X
S0004-282X2009000300038
WOS:000268140200038
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos de Neuro-Psiquiatria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 548-552
application/pdf
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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