Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics

Detalhes bibliográficos
Autor(a) principal: Guedes, Zelita Caldeira Ferreira
Data de Publicação: 2014
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1055/s-0033-1363466
http://repositorio.unifesp.br/handle/11600/8566
Resumo: Introduction Möbius syndrome (MS; VI and VII palsy) is a rare disease that in Brazil has a great frequency because of the use of misoprostol during pregnancy. Objective Verify if the speech and language performance of children with MS whose mothers reported use of misoprostol (Cytotec, Pfizer, Connecticut, USA) are different from the performance of children of mothers who did not report use. Methods The stomatognathic system beyond receptive and expressive language and speech was evaluated in children with MS, and their mothers were questioned whether they used misoprostol during the pregnancy. Results During the interview, 61.11% of mothers reported that they took misoprostol during the pregnancy. Most of the subjects (83.3%) whose mothers took misoprostol presented bilateral palsy beyond bad mobility of the tongue (90.9%) and speech disorders (63.6%). Conclusion The number of mothers who took misoprostol without knowing the risk for MS was great. The lack of facial expressions and speech disorders were common characteristics of the individuals with MS, whether the mothers took misoprostol during the pregnancy or not.
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spelling Möbius Syndrome: Misoprostol Use and Speech and Language Characteristicsmisoprostolspeech disordersrehabilitation of speech and language disordersIntroduction Möbius syndrome (MS; VI and VII palsy) is a rare disease that in Brazil has a great frequency because of the use of misoprostol during pregnancy. Objective Verify if the speech and language performance of children with MS whose mothers reported use of misoprostol (Cytotec, Pfizer, Connecticut, USA) are different from the performance of children of mothers who did not report use. Methods The stomatognathic system beyond receptive and expressive language and speech was evaluated in children with MS, and their mothers were questioned whether they used misoprostol during the pregnancy. Results During the interview, 61.11% of mothers reported that they took misoprostol during the pregnancy. Most of the subjects (83.3%) whose mothers took misoprostol presented bilateral palsy beyond bad mobility of the tongue (90.9%) and speech disorders (63.6%). Conclusion The number of mothers who took misoprostol without knowing the risk for MS was great. The lack of facial expressions and speech disorders were common characteristics of the individuals with MS, whether the mothers took misoprostol during the pregnancy or not.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Department of Speech and LanguageUNIFESP, EPM, Department of Speech and LanguageSciELOFundação OtorrinolaringologiaUniversidade Federal de São Paulo (UNIFESP)Guedes, Zelita Caldeira Ferreira2015-06-14T13:47:16Z2015-06-14T13:47:16Z2014-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion239-243application/pdfhttp://dx.doi.org/10.1055/s-0033-1363466International Archives of Otorhinolaryngology. Fundação Otorrinolaringologia, v. 18, n. 3, p. 239-243, 2014.10.1055/s-0033-1363466S1809-48642014000300239.pdf1809-4864S1809-48642014000300239http://repositorio.unifesp.br/handle/11600/8566engInternational Archives of Otorhinolaryngologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T08:07:16Zoai:repositorio.unifesp.br/:11600/8566Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-05T08:07:16Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics
title Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics
spellingShingle Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics
Guedes, Zelita Caldeira Ferreira
misoprostol
speech disorders
rehabilitation of speech and language disorders
title_short Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics
title_full Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics
title_fullStr Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics
title_full_unstemmed Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics
title_sort Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics
author Guedes, Zelita Caldeira Ferreira
author_facet Guedes, Zelita Caldeira Ferreira
author_role author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Guedes, Zelita Caldeira Ferreira
dc.subject.por.fl_str_mv misoprostol
speech disorders
rehabilitation of speech and language disorders
topic misoprostol
speech disorders
rehabilitation of speech and language disorders
description Introduction Möbius syndrome (MS; VI and VII palsy) is a rare disease that in Brazil has a great frequency because of the use of misoprostol during pregnancy. Objective Verify if the speech and language performance of children with MS whose mothers reported use of misoprostol (Cytotec, Pfizer, Connecticut, USA) are different from the performance of children of mothers who did not report use. Methods The stomatognathic system beyond receptive and expressive language and speech was evaluated in children with MS, and their mothers were questioned whether they used misoprostol during the pregnancy. Results During the interview, 61.11% of mothers reported that they took misoprostol during the pregnancy. Most of the subjects (83.3%) whose mothers took misoprostol presented bilateral palsy beyond bad mobility of the tongue (90.9%) and speech disorders (63.6%). Conclusion The number of mothers who took misoprostol without knowing the risk for MS was great. The lack of facial expressions and speech disorders were common characteristics of the individuals with MS, whether the mothers took misoprostol during the pregnancy or not.
publishDate 2014
dc.date.none.fl_str_mv 2014-09-01
2015-06-14T13:47:16Z
2015-06-14T13:47:16Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1055/s-0033-1363466
International Archives of Otorhinolaryngology. Fundação Otorrinolaringologia, v. 18, n. 3, p. 239-243, 2014.
10.1055/s-0033-1363466
S1809-48642014000300239.pdf
1809-4864
S1809-48642014000300239
http://repositorio.unifesp.br/handle/11600/8566
url http://dx.doi.org/10.1055/s-0033-1363466
http://repositorio.unifesp.br/handle/11600/8566
identifier_str_mv International Archives of Otorhinolaryngology. Fundação Otorrinolaringologia, v. 18, n. 3, p. 239-243, 2014.
10.1055/s-0033-1363466
S1809-48642014000300239.pdf
1809-4864
S1809-48642014000300239
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Archives of Otorhinolaryngology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 239-243
application/pdf
dc.publisher.none.fl_str_mv Fundação Otorrinolaringologia
publisher.none.fl_str_mv Fundação Otorrinolaringologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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