Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama

Detalhes bibliográficos
Autor(a) principal: Pinto, Vania Lopes [UNIFESP]
Data de Publicação: 2020
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=10133662
https://hdl.handle.net/11600/64827
Resumo: Objective: to identify the prevalence of xerostomia in women diagnosed with breast cancer and undergoing chemotherapy treatment in a public reference service in the city of São Paulo. Method: prospective cohort with women diagnosed with any malignant breast cancer, with or without previous surgical procedure and / or previous chemotherapy, in outpatient care. Women who discontinued or abandoned treatment during the data collection period, those who changed their treatment to non-chemotherapy, and those who needed a regimen with more than 16 sessions were excluded only the surpluses. The sample calculation predicted an expected error of 17% at an expected prevalence of 50% and with a significance level of 95% therefore considered a sample of 27 women followed up at the end of treatment. The research respected all stages of study with human beings, including obtaining the signature of the Informed Consent Form and submitting it to the Research Ethics Committee. Data collection was performed using two instruments built by the researchers to identify the sample characterization data and anamnesis of the oral cavity. The identification of dry mouth was assessed by means of a validated xerostomia evaluation questionnaire cross-culturally adapted to the Portuguese language, which was applied before the beginning of treatment and after each administration of chemotherapy. Results: All women in the study were from the State of São Paulo aged 35 to 77 years and with an average of nine years of schooling. Dry mouth complaints were present in 48.1% of women before chemotherapy and they were 28 times more likely to develop xerostomia during treatment. It was observed that the use of antiemetics contributed to the increased occurrence of xerostomia and the antiulcerants presented as a protective factor. Conclusion: the present study identified the prevalence of xerostomia in the studied population of 75.4%.
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spelling Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mamaPrevalence of xerostomia in women during breast cancer chemotherapyXerostomiaBreast NeoplasmsPharmacological TreatmentXerostomiaNeoplasias Da MamaTratamento FarmacológicoObjective: to identify the prevalence of xerostomia in women diagnosed with breast cancer and undergoing chemotherapy treatment in a public reference service in the city of São Paulo. Method: prospective cohort with women diagnosed with any malignant breast cancer, with or without previous surgical procedure and / or previous chemotherapy, in outpatient care. Women who discontinued or abandoned treatment during the data collection period, those who changed their treatment to non-chemotherapy, and those who needed a regimen with more than 16 sessions were excluded only the surpluses. The sample calculation predicted an expected error of 17% at an expected prevalence of 50% and with a significance level of 95% therefore considered a sample of 27 women followed up at the end of treatment. The research respected all stages of study with human beings, including obtaining the signature of the Informed Consent Form and submitting it to the Research Ethics Committee. Data collection was performed using two instruments built by the researchers to identify the sample characterization data and anamnesis of the oral cavity. The identification of dry mouth was assessed by means of a validated xerostomia evaluation questionnaire cross-culturally adapted to the Portuguese language, which was applied before the beginning of treatment and after each administration of chemotherapy. Results: All women in the study were from the State of São Paulo aged 35 to 77 years and with an average of nine years of schooling. Dry mouth complaints were present in 48.1% of women before chemotherapy and they were 28 times more likely to develop xerostomia during treatment. It was observed that the use of antiemetics contributed to the increased occurrence of xerostomia and the antiulcerants presented as a protective factor. Conclusion: the present study identified the prevalence of xerostomia in the studied population of 75.4%.Objetivo: identificar a prevalência da xerostomia em mulheres diagnosticadas com câncer de mama e submetidas a tratamento quimioterápico em serviço público de referência na cidade de São Paulo. Método: coorte prospectiva com mulheres diagnosticadas com qualquer neoplasia maligna da mama, com ou sem procedimento cirúrgico prévio e/ou quimioterapia anterior, em atendimento ambulatorial. Foram excluídas as mulheres que interromperam ou abandonaram o tratamento durante o período de coleta de dados, as que o tratamento foi modificado para não quimioterápico e aquelas que necessitaram de um esquema com mais de 16 sessões foram excluídas apenas as excedentes. O cálculo amostral previu um erro esperado de 17% em uma prevalência esperada de 50% e com nível de significância de 95% considerou, portanto, uma amostra de 27 mulheres acompanhadas até o final do tratamento. A pesquisa respeitou todas as etapas de estudo com seres humano, incluindo a obtenção da assinatura do Termo de Consentimento Livre e Esclarecido e submissão ao Comitê de Ética em Pesquisa. A coleta de dados foi realizada por meio de dois instrumentos construídos pelos pesquisadores para a identificação dos dados de caracterização da amostra e anamnese da cavidade oral aplicado antes da quimioterapia. A identificação da boca seca por meio de um questionário de avaliação da xerostomia validado e adaptado transculturalmente para o idioma português que foi aplicado antes do inicio do tratamento e após cada administração do quimioterápico. Resultados: todas as mulheres no estudo eram procedentes do Estado de São Paulo com idades entre 35 a 77 anos e com uma média de nove anos de escolaridade. A queixa de boca seca esteve presente em 48,1% das mulheres antes da quimioterapia e elas tiveram 28 vezes mais chance de desenvolver a xerostomia durante o tratamento. Observou-se que o uso de antieméticos contribuiu para o aumento da ocorrência de xerostomia e os antiulcerosos se apresentaram como fator de proteção. Conclusão: o presente estudo identificou a prevalência da xerostomia na população estudada de 75,4%.Dados abertos - Sucupira - Teses e dissertações (2020)Universidade Federal de São Paulo (UNIFESP)Elias, Simone [UNIFESP]http://lattes.cnpq.br/7745925386381770http://lattes.cnpq.br/8078552208250536Universidade Federal de São PauloPinto, Vania Lopes [UNIFESP]2022-07-22T17:29:13Z2022-07-22T17:29:13Z2020-01-30info:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/publishedVersion48 f.application/pdfhttps://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=10133662PINTO, Vânia Lopes. Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama. 2019. 48f. Dissertação (Mestrado em Ginecologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.VÂNIA LOPES PINTO-A.pdfhttps://hdl.handle.net/11600/64827porSão Pauloinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-19T09:11:52Zoai:repositorio.unifesp.br/:11600/64827Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-19T09:11:52Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama
Prevalence of xerostomia in women during breast cancer chemotherapy
title Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama
spellingShingle Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama
Pinto, Vania Lopes [UNIFESP]
Xerostomia
Breast Neoplasms
Pharmacological Treatment
Xerostomia
Neoplasias Da Mama
Tratamento Farmacológico
title_short Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama
title_full Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama
title_fullStr Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama
title_full_unstemmed Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama
title_sort Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama
author Pinto, Vania Lopes [UNIFESP]
author_facet Pinto, Vania Lopes [UNIFESP]
author_role author
dc.contributor.none.fl_str_mv Elias, Simone [UNIFESP]
http://lattes.cnpq.br/7745925386381770
http://lattes.cnpq.br/8078552208250536
Universidade Federal de São Paulo
dc.contributor.author.fl_str_mv Pinto, Vania Lopes [UNIFESP]
dc.subject.por.fl_str_mv Xerostomia
Breast Neoplasms
Pharmacological Treatment
Xerostomia
Neoplasias Da Mama
Tratamento Farmacológico
topic Xerostomia
Breast Neoplasms
Pharmacological Treatment
Xerostomia
Neoplasias Da Mama
Tratamento Farmacológico
description Objective: to identify the prevalence of xerostomia in women diagnosed with breast cancer and undergoing chemotherapy treatment in a public reference service in the city of São Paulo. Method: prospective cohort with women diagnosed with any malignant breast cancer, with or without previous surgical procedure and / or previous chemotherapy, in outpatient care. Women who discontinued or abandoned treatment during the data collection period, those who changed their treatment to non-chemotherapy, and those who needed a regimen with more than 16 sessions were excluded only the surpluses. The sample calculation predicted an expected error of 17% at an expected prevalence of 50% and with a significance level of 95% therefore considered a sample of 27 women followed up at the end of treatment. The research respected all stages of study with human beings, including obtaining the signature of the Informed Consent Form and submitting it to the Research Ethics Committee. Data collection was performed using two instruments built by the researchers to identify the sample characterization data and anamnesis of the oral cavity. The identification of dry mouth was assessed by means of a validated xerostomia evaluation questionnaire cross-culturally adapted to the Portuguese language, which was applied before the beginning of treatment and after each administration of chemotherapy. Results: All women in the study were from the State of São Paulo aged 35 to 77 years and with an average of nine years of schooling. Dry mouth complaints were present in 48.1% of women before chemotherapy and they were 28 times more likely to develop xerostomia during treatment. It was observed that the use of antiemetics contributed to the increased occurrence of xerostomia and the antiulcerants presented as a protective factor. Conclusion: the present study identified the prevalence of xerostomia in the studied population of 75.4%.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-30
2022-07-22T17:29:13Z
2022-07-22T17:29:13Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=10133662
PINTO, Vânia Lopes. Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama. 2019. 48f. Dissertação (Mestrado em Ginecologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.
VÂNIA LOPES PINTO-A.pdf
https://hdl.handle.net/11600/64827
url https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=10133662
https://hdl.handle.net/11600/64827
identifier_str_mv PINTO, Vânia Lopes. Prevalência de xerostomia em mulheres durante a quimioterapia por câncer de mama. 2019. 48f. Dissertação (Mestrado em Ginecologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.
VÂNIA LOPES PINTO-A.pdf
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 48 f.
application/pdf
dc.coverage.none.fl_str_mv São Paulo
dc.publisher.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
publisher.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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