The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases

Detalhes bibliográficos
Autor(a) principal: Queiroz, Matheus Trovao de [UNIFESP]
Data de Publicação: 2016
Outros Autores: Pereira, Vanessa Goncalves [UNIFESP], Nascimento, Cinthia Castro do [UNIFESP], D'Almeida, Vania [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.3389/fendo.2016.00133
https://repositorio.unifesp.br/handle/11600/57100
Resumo: Non-coding RNAs (ncRNAs) are a functional class of RNA involved in the regulation of several cellular processes which may modulate disease onset, progression, and prognosis. Lysosomal storage diseases (LSD) are a group of rare disorders caused by mutations of genes encoding specific hydrolases or non-enzymatic proteins, characterized by a wide spectrum of manifestations. The alteration of ncRNA levels is well established in several human diseases such as cancer and auto-immune disorders
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spelling The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseasesnon-coding RNAlysosomal storage diseaselysosomemiRNAsiRNANon-coding RNAs (ncRNAs) are a functional class of RNA involved in the regulation of several cellular processes which may modulate disease onset, progression, and prognosis. Lysosomal storage diseases (LSD) are a group of rare disorders caused by mutations of genes encoding specific hydrolases or non-enzymatic proteins, characterized by a wide spectrum of manifestations. The alteration of ncRNA levels is well established in several human diseases such as cancer and auto-immune disordershowever, there is a lack of information focused on the role of ncRNA in rare diseases. Recent reports related to changes in ncRNA expression and its consequences on LSD physiopathology show us the importance to keep advancing in this field. This article will summarize recent findings and provide key points for further studies on LSD and ncRNA association.Univ Fed Sao Paulo, Dept Psychobiol, Lab Erros Inatos Metab, Sao Paulo, BrazilUniv Fed Sao Paulo, Dept Pediat, Sao Paulo, BrazilLaboratório de Erros Inatos do Metabolismo, Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, BrazilDepartment of Pediatrics, Universidade Federal de São Paulo, São Paulo, BrazilWeb of ScienceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Instituto de Genetica e Erros Inatos do Metabolismo (IGEIM)Associação Fundo de Incentivo à Psicofarmacologia (AFIP)FAPESP: 2014/14230-0FAPESP: 2015/053818Frontiers Media Sa2020-07-31T12:47:48Z2020-07-31T12:47:48Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion-application/pdfhttp://dx.doi.org/10.3389/fendo.2016.00133Frontiers In Endocrinology. Lausanne, v. 7, p. -, 2016.10.3389/fendo.2016.00133WOS000385361700001.pdf1664-2392https://repositorio.unifesp.br/handle/11600/57100WOS:000385361700001engFrontiers In EndocrinologyLausanneinfo:eu-repo/semantics/openAccessQueiroz, Matheus Trovao de [UNIFESP]Pereira, Vanessa Goncalves [UNIFESP]Nascimento, Cinthia Castro do [UNIFESP]D'Almeida, Vania [UNIFESP]reponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-11T19:41:26Zoai:repositorio.unifesp.br/:11600/57100Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-11T19:41:26Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases
title The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases
spellingShingle The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases
Queiroz, Matheus Trovao de [UNIFESP]
non-coding RNA
lysosomal storage disease
lysosome
miRNA
siRNA
title_short The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases
title_full The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases
title_fullStr The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases
title_full_unstemmed The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases
title_sort The Underexploited Role of Non-Coding RNAs in Lysosomal Storage Diseases
author Queiroz, Matheus Trovao de [UNIFESP]
author_facet Queiroz, Matheus Trovao de [UNIFESP]
Pereira, Vanessa Goncalves [UNIFESP]
Nascimento, Cinthia Castro do [UNIFESP]
D'Almeida, Vania [UNIFESP]
author_role author
author2 Pereira, Vanessa Goncalves [UNIFESP]
Nascimento, Cinthia Castro do [UNIFESP]
D'Almeida, Vania [UNIFESP]
author2_role author
author
author
dc.contributor.author.fl_str_mv Queiroz, Matheus Trovao de [UNIFESP]
Pereira, Vanessa Goncalves [UNIFESP]
Nascimento, Cinthia Castro do [UNIFESP]
D'Almeida, Vania [UNIFESP]
dc.subject.por.fl_str_mv non-coding RNA
lysosomal storage disease
lysosome
miRNA
siRNA
topic non-coding RNA
lysosomal storage disease
lysosome
miRNA
siRNA
description Non-coding RNAs (ncRNAs) are a functional class of RNA involved in the regulation of several cellular processes which may modulate disease onset, progression, and prognosis. Lysosomal storage diseases (LSD) are a group of rare disorders caused by mutations of genes encoding specific hydrolases or non-enzymatic proteins, characterized by a wide spectrum of manifestations. The alteration of ncRNA levels is well established in several human diseases such as cancer and auto-immune disorders
publishDate 2016
dc.date.none.fl_str_mv 2016
2020-07-31T12:47:48Z
2020-07-31T12:47:48Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3389/fendo.2016.00133
Frontiers In Endocrinology. Lausanne, v. 7, p. -, 2016.
10.3389/fendo.2016.00133
WOS000385361700001.pdf
1664-2392
https://repositorio.unifesp.br/handle/11600/57100
WOS:000385361700001
url http://dx.doi.org/10.3389/fendo.2016.00133
https://repositorio.unifesp.br/handle/11600/57100
identifier_str_mv Frontiers In Endocrinology. Lausanne, v. 7, p. -, 2016.
10.3389/fendo.2016.00133
WOS000385361700001.pdf
1664-2392
WOS:000385361700001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Frontiers In Endocrinology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv -
application/pdf
dc.coverage.none.fl_str_mv Lausanne
dc.publisher.none.fl_str_mv Frontiers Media Sa
publisher.none.fl_str_mv Frontiers Media Sa
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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