Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass

Detalhes bibliográficos
Autor(a) principal: Zilli, Alexandre Cabral [UNIFESP]
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7756899
https://repositorio.unifesp.br/handle/11600/59216
Resumo: BACKGROUND: Valvular heart diseases are the second cause of cardiac surgeries in the world. However, the patients’ profile, etiology of valve diseases and surgical results differ according to the population and country studied. In Brazil, the BYPASS (Brazilian Registry of Cardiovascular Surgeries in Adults) project aims to map the epidemiological aspects and results of surgical treatment of patients with heart disease. OBJECTIVE: To analyze the profile of valvular heart surgery performed in Brazil, using the BYPASS Registry database. METHOD: A multicenter observational / prospective cohort study with 17 participating centers in Brazil. We evaluated 920 patients submitted to cardiac valve surgeries isolated and / or associated from August 2014 to April 2018. Postoperative clinical outcomes: cardiopulmonary and infectious complications, length of stay in the Intensive Care Unit and hospital in the post-operatory and mortality, compared to estimated calculated mortality risk by EuroSCORE (European System for Cardiac Operative Risk Evaluation). RESULTS: The mean age of the patients was 56.7 years and women represented 47%. Isolated aortic valve replacement was the most frequently performed surgery (34%), followed by isolated mitral valve replacement (24.9%) and double-mitro-aortic valve replacement (13.3%). Valve repair was performed in 21% of mitral procedures. Minimally invasive access was performed at 1.6%. Invasive mechanical ventilation post-op >24hours occurred in 8.2%. The most frequent postoperative complications were arrhythmias (22,6%), infections (5.7%- 27% in surgical focus) and low-output syndrome (5.1%). Surgeries by the public system (Unique Health System) accounted for 80.8%. The hospital mortality rate was 7.3%, while mean logistic EuroSCORE was 7.9%. The rheumatic etiopathogenesis occurred in 38.3% of the operated patients. CONCLUSION: The most frequent isolated valve surgery in Brazil is the aortic valve replacement by conventional open access, followed by mitral valve replacement surgery and double valve replacement. Rheumatic disease was the main ethiopathogenic cause of valve surgeries in Brazil. Hospital mortality of valvular cardiac surgeries match corresponding logistic risk stratification by EuroScore, showing a medium to high risk population operated. The BYPASS registry became a fundamental tool to know the profile of patients with valve heart disease in our country in order to delineate adequate strategies for health promotion and resource allocation for cardiac surgery.
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spelling Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro BypassCardiac Valve Surgeries Profile in Brazil – BYPASS Registry Analysis.Mortality Risk Stratification ScorePost-Operatory ComplicationsRheumatic Valve DiseaseValve Heart DiseaseOperative MortalityValvopatiasEscores De Risco De Mortalidade Cirúrgica.Complicações Pós-OperatóriasMortalidade HospitalarCirurgias Cardíacas ValvaresDoença Valvar ReumáticaBACKGROUND: Valvular heart diseases are the second cause of cardiac surgeries in the world. However, the patients’ profile, etiology of valve diseases and surgical results differ according to the population and country studied. In Brazil, the BYPASS (Brazilian Registry of Cardiovascular Surgeries in Adults) project aims to map the epidemiological aspects and results of surgical treatment of patients with heart disease. OBJECTIVE: To analyze the profile of valvular heart surgery performed in Brazil, using the BYPASS Registry database. METHOD: A multicenter observational / prospective cohort study with 17 participating centers in Brazil. We evaluated 920 patients submitted to cardiac valve surgeries isolated and / or associated from August 2014 to April 2018. Postoperative clinical outcomes: cardiopulmonary and infectious complications, length of stay in the Intensive Care Unit and hospital in the post-operatory and mortality, compared to estimated calculated mortality risk by EuroSCORE (European System for Cardiac Operative Risk Evaluation). RESULTS: The mean age of the patients was 56.7 years and women represented 47%. Isolated aortic valve replacement was the most frequently performed surgery (34%), followed by isolated mitral valve replacement (24.9%) and double-mitro-aortic valve replacement (13.3%). Valve repair was performed in 21% of mitral procedures. Minimally invasive access was performed at 1.6%. Invasive mechanical ventilation post-op >24hours occurred in 8.2%. The most frequent postoperative complications were arrhythmias (22,6%), infections (5.7%- 27% in surgical focus) and low-output syndrome (5.1%). Surgeries by the public system (Unique Health System) accounted for 80.8%. The hospital mortality rate was 7.3%, while mean logistic EuroSCORE was 7.9%. The rheumatic etiopathogenesis occurred in 38.3% of the operated patients. CONCLUSION: The most frequent isolated valve surgery in Brazil is the aortic valve replacement by conventional open access, followed by mitral valve replacement surgery and double valve replacement. Rheumatic disease was the main ethiopathogenic cause of valve surgeries in Brazil. Hospital mortality of valvular cardiac surgeries match corresponding logistic risk stratification by EuroScore, showing a medium to high risk population operated. The BYPASS registry became a fundamental tool to know the profile of patients with valve heart disease in our country in order to delineate adequate strategies for health promotion and resource allocation for cardiac surgery.FUNDAMENTO: As doenças valvares constituem a segunda causa de cirurgias cardíacas no mundo. No entanto, o perfil dos pacientes e resultados diferem de acordo com a população e país estudado. No Brasil, o projeto BYPASS (Registro Brasileiro de Cirurgias Cardiovasculares em Adultos) visa mapear os aspectos epidemiológicos e resultados do tratamento cirúrgico dos pacientes com doenças cardíacas. OBJETIVO: Analisar o perfil das cirurgias cardíacas valvares realizadas no Brasil utilizando o banco de dados do registro BYPASS. MÉTODO: Estudo multicêntrico observacional/coorte prospectivo com 17 centros participantes no Brasil. Foram avaliados 920 pacientes submetidos a cirurgias valvares, isoladas e/ou associadas, de agosto de 2014 a abril de 2018. Os desfechos clínicos pós-operatórios avaliados foram: complicações cardiopulmonares e infecciosas; tempos de internação em Unidade de Terapia Intensiva e hospitalar no PO e mortalidade, comparada a mortalidade prevista calculada pelo EuroSCORE (Sistema Europeu de Avaliação do Risco Cirúrgico em Cirurgia Cardíaca). RESULTADOS: A idade média dos pacientes foi de 56,7 anos e mulheres representaram 47%. A troca valvar aórtica isolada foi a cirurgia mais frequentemente realizada (34%), seguida da troca valvar mitral isolada (24,9%) e posteriormente da dupla troca valvar mitro-aórtica (13,3%). A plastia valvar mitral representou 21% dos procedimentos mitrais. Acesso minimamente invasivo foi realizado em 1,6%. Ventilação mecânica invasiva no pós-operatório >24 horas ocorreu em 8,2%. As complicações pós-operatórias mais frequentes foram arritmias (22,6%) e infecções (5,7%), - ocorrendo em 27% no sítio cirúrgico. Cirurgias custeadas pelo sistema público – Sistema Único de Saúde representaram 80,8%. A mortalidade hospitalar foi de 7,3% enquanto o EuroSCORE Log médio de 7,9%. A etiopatogenia reumática ocorreu em 38,3% dos pacientes operados, enquanto a degenerativa senil aórtica em 13,2%. CONCLUSÃO: A cirurgia valvar isolada mais frequente no Brasil foi a troca valvar aórtica por acesso aberto convencional, seguida pela cirurgia de troca valvar mitral e a dupla troca valvar. A etiopatogenia mais comum encontrada ainda foi a reumática. A mortalidade das cirurgias cardíacas valvares no Brasil foi compatível com o risco cirúrgico estimado pelo EuroSCORE, evidenciando uma população de médio-alto risco cirúrgico operada no país. O registro BYPASS se tornou de fundamental importância para conhecermos o perfil dos pacientes com doença valvar em nosso país a fim de delinear estratégias adequadas para promoção de saúde e alocação de recursos para cirurgia cardíaca.Dados abertos - Sucupira - Teses e dissertações (2019)Universidade Federal de São Paulo (UNIFESP)Gomes, Walter Jose [UNIFESP]Guizilini, Solange [UNIFESP]http://lattes.cnpq.br/1563905009199506http://lattes.cnpq.br/9877675594064089Universidade Federal de São Paulo (UNIFESP)Zilli, Alexandre Cabral [UNIFESP]2021-01-19T16:31:56Z2021-01-19T16:31:56Z2019-09-26info:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/publishedVersion75 f.application/pdfhttps://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7756899ZILLI, Alexandre Cabral. Perfil das cirurgias cardíacas valvares no Brasil – Análise do registro Bypass. 2019. 75f. Dissertação (Mestrado em Cardiologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.ALEXANDRE CABRAL ZILLI-A.pdfhttps://repositorio.unifesp.br/handle/11600/59216porinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-02T23:50:34Zoai:repositorio.unifesp.br/:11600/59216Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-02T23:50:34Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass
Cardiac Valve Surgeries Profile in Brazil – BYPASS Registry Analysis.
title Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass
spellingShingle Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass
Zilli, Alexandre Cabral [UNIFESP]
Mortality Risk Stratification Score
Post-Operatory Complications
Rheumatic Valve Disease
Valve Heart Disease
Operative Mortality
Valvopatias
Escores De Risco De Mortalidade Cirúrgica.
Complicações Pós-Operatórias
Mortalidade Hospitalar
Cirurgias Cardíacas Valvares
Doença Valvar Reumática
title_short Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass
title_full Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass
title_fullStr Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass
title_full_unstemmed Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass
title_sort Perfil das Cirurgias Cardíacas Valvares no Brasil Análise do Registro Bypass
author Zilli, Alexandre Cabral [UNIFESP]
author_facet Zilli, Alexandre Cabral [UNIFESP]
author_role author
dc.contributor.none.fl_str_mv Gomes, Walter Jose [UNIFESP]
Guizilini, Solange [UNIFESP]
http://lattes.cnpq.br/1563905009199506
http://lattes.cnpq.br/9877675594064089
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Zilli, Alexandre Cabral [UNIFESP]
dc.subject.por.fl_str_mv Mortality Risk Stratification Score
Post-Operatory Complications
Rheumatic Valve Disease
Valve Heart Disease
Operative Mortality
Valvopatias
Escores De Risco De Mortalidade Cirúrgica.
Complicações Pós-Operatórias
Mortalidade Hospitalar
Cirurgias Cardíacas Valvares
Doença Valvar Reumática
topic Mortality Risk Stratification Score
Post-Operatory Complications
Rheumatic Valve Disease
Valve Heart Disease
Operative Mortality
Valvopatias
Escores De Risco De Mortalidade Cirúrgica.
Complicações Pós-Operatórias
Mortalidade Hospitalar
Cirurgias Cardíacas Valvares
Doença Valvar Reumática
description BACKGROUND: Valvular heart diseases are the second cause of cardiac surgeries in the world. However, the patients’ profile, etiology of valve diseases and surgical results differ according to the population and country studied. In Brazil, the BYPASS (Brazilian Registry of Cardiovascular Surgeries in Adults) project aims to map the epidemiological aspects and results of surgical treatment of patients with heart disease. OBJECTIVE: To analyze the profile of valvular heart surgery performed in Brazil, using the BYPASS Registry database. METHOD: A multicenter observational / prospective cohort study with 17 participating centers in Brazil. We evaluated 920 patients submitted to cardiac valve surgeries isolated and / or associated from August 2014 to April 2018. Postoperative clinical outcomes: cardiopulmonary and infectious complications, length of stay in the Intensive Care Unit and hospital in the post-operatory and mortality, compared to estimated calculated mortality risk by EuroSCORE (European System for Cardiac Operative Risk Evaluation). RESULTS: The mean age of the patients was 56.7 years and women represented 47%. Isolated aortic valve replacement was the most frequently performed surgery (34%), followed by isolated mitral valve replacement (24.9%) and double-mitro-aortic valve replacement (13.3%). Valve repair was performed in 21% of mitral procedures. Minimally invasive access was performed at 1.6%. Invasive mechanical ventilation post-op >24hours occurred in 8.2%. The most frequent postoperative complications were arrhythmias (22,6%), infections (5.7%- 27% in surgical focus) and low-output syndrome (5.1%). Surgeries by the public system (Unique Health System) accounted for 80.8%. The hospital mortality rate was 7.3%, while mean logistic EuroSCORE was 7.9%. The rheumatic etiopathogenesis occurred in 38.3% of the operated patients. CONCLUSION: The most frequent isolated valve surgery in Brazil is the aortic valve replacement by conventional open access, followed by mitral valve replacement surgery and double valve replacement. Rheumatic disease was the main ethiopathogenic cause of valve surgeries in Brazil. Hospital mortality of valvular cardiac surgeries match corresponding logistic risk stratification by EuroScore, showing a medium to high risk population operated. The BYPASS registry became a fundamental tool to know the profile of patients with valve heart disease in our country in order to delineate adequate strategies for health promotion and resource allocation for cardiac surgery.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-26
2021-01-19T16:31:56Z
2021-01-19T16:31:56Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7756899
ZILLI, Alexandre Cabral. Perfil das cirurgias cardíacas valvares no Brasil – Análise do registro Bypass. 2019. 75f. Dissertação (Mestrado em Cardiologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.
ALEXANDRE CABRAL ZILLI-A.pdf
https://repositorio.unifesp.br/handle/11600/59216
url https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7756899
https://repositorio.unifesp.br/handle/11600/59216
identifier_str_mv ZILLI, Alexandre Cabral. Perfil das cirurgias cardíacas valvares no Brasil – Análise do registro Bypass. 2019. 75f. Dissertação (Mestrado em Cardiologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.
ALEXANDRE CABRAL ZILLI-A.pdf
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 75 f.
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
publisher.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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