Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1155/2014/890823 http://repositorio.unifesp.br/handle/11600/37160 |
Resumo: | Corneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysis of some established topics and others that are still controversial. in addition, this review examines new technologies and techniques (transepithelial and ultrafast CXL), uses of corneal CXL including natural products and biomolecules as CXL promoters, and evidence for in vitro and in vivo indirect effectiveness. |
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Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-LinkingCorneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysis of some established topics and others that are still controversial. in addition, this review examines new technologies and techniques (transepithelial and ultrafast CXL), uses of corneal CXL including natural products and biomolecules as CXL promoters, and evidence for in vitro and in vivo indirect effectiveness.Fed Univ São Paulo UNIFESP, Paulista Sch Med, Dept Ophthalmol & Visual Sci, São Paulo, BrazilFed Univ São Paulo UNIFESP, Paulista Sch Med, Dept Hlth Informat, BR-04023062 São Paulo, BrazilInst Olhos Renato Ambrosio, BR-20520050 Rio de Janeiro, RJ, BrazilFed Univ São Paulo UNIFESP, Paulista Sch Med, Dept Ophthalmol & Visual Sci, São Paulo, BrazilFed Univ São Paulo UNIFESP, Paulista Sch Med, Dept Hlth Informat, BR-04023062 São Paulo, BrazilWeb of ScienceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FAPESP: 2012/07343-8FAPESP: 2013/20857-3Hindawi Publishing CorporationUniversidade Federal de São Paulo (UNIFESP)Inst Olhos Renato AmbrosioPaz, Amanda C. da [UNIFESP]Bersanetti, Patricia A. [UNIFESP]Salomao, Marcella Q.Ambrosio, Renato [UNIFESP]Schor, Paulo [UNIFESP]2016-01-24T14:34:57Z2016-01-24T14:34:57Z2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion9application/pdfhttp://dx.doi.org/10.1155/2014/890823Journal of Ophthalmology. New York: Hindawi Publishing Corporation, 9 p., 2014.10.1155/2014/890823WOS000344168700001.pdf2090-004Xhttp://repositorio.unifesp.br/handle/11600/37160WOS:000344168700001engJournal of Ophthalmologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-31T17:31:45Zoai:repositorio.unifesp.br/:11600/37160Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-31T17:31:45Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
title |
Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
spellingShingle |
Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking Paz, Amanda C. da [UNIFESP] |
title_short |
Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
title_full |
Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
title_fullStr |
Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
title_full_unstemmed |
Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
title_sort |
Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking |
author |
Paz, Amanda C. da [UNIFESP] |
author_facet |
Paz, Amanda C. da [UNIFESP] Bersanetti, Patricia A. [UNIFESP] Salomao, Marcella Q. Ambrosio, Renato [UNIFESP] Schor, Paulo [UNIFESP] |
author_role |
author |
author2 |
Bersanetti, Patricia A. [UNIFESP] Salomao, Marcella Q. Ambrosio, Renato [UNIFESP] Schor, Paulo [UNIFESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Inst Olhos Renato Ambrosio |
dc.contributor.author.fl_str_mv |
Paz, Amanda C. da [UNIFESP] Bersanetti, Patricia A. [UNIFESP] Salomao, Marcella Q. Ambrosio, Renato [UNIFESP] Schor, Paulo [UNIFESP] |
description |
Corneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysis of some established topics and others that are still controversial. in addition, this review examines new technologies and techniques (transepithelial and ultrafast CXL), uses of corneal CXL including natural products and biomolecules as CXL promoters, and evidence for in vitro and in vivo indirect effectiveness. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 2016-01-24T14:34:57Z 2016-01-24T14:34:57Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1155/2014/890823 Journal of Ophthalmology. New York: Hindawi Publishing Corporation, 9 p., 2014. 10.1155/2014/890823 WOS000344168700001.pdf 2090-004X http://repositorio.unifesp.br/handle/11600/37160 WOS:000344168700001 |
url |
http://dx.doi.org/10.1155/2014/890823 http://repositorio.unifesp.br/handle/11600/37160 |
identifier_str_mv |
Journal of Ophthalmology. New York: Hindawi Publishing Corporation, 9 p., 2014. 10.1155/2014/890823 WOS000344168700001.pdf 2090-004X WOS:000344168700001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Ophthalmology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
9 application/pdf |
dc.publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268413148659712 |