Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking

Detalhes bibliográficos
Autor(a) principal: Paz, Amanda C. da [UNIFESP]
Data de Publicação: 2014
Outros Autores: Bersanetti, Patricia A. [UNIFESP], Salomao, Marcella Q., Ambrosio, Renato [UNIFESP], Schor, Paulo [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1155/2014/890823
http://repositorio.unifesp.br/handle/11600/37160
Resumo: Corneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysis of some established topics and others that are still controversial. in addition, this review examines new technologies and techniques (transepithelial and ultrafast CXL), uses of corneal CXL including natural products and biomolecules as CXL promoters, and evidence for in vitro and in vivo indirect effectiveness.
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spelling Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-LinkingCorneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysis of some established topics and others that are still controversial. in addition, this review examines new technologies and techniques (transepithelial and ultrafast CXL), uses of corneal CXL including natural products and biomolecules as CXL promoters, and evidence for in vitro and in vivo indirect effectiveness.Fed Univ São Paulo UNIFESP, Paulista Sch Med, Dept Ophthalmol & Visual Sci, São Paulo, BrazilFed Univ São Paulo UNIFESP, Paulista Sch Med, Dept Hlth Informat, BR-04023062 São Paulo, BrazilInst Olhos Renato Ambrosio, BR-20520050 Rio de Janeiro, RJ, BrazilFed Univ São Paulo UNIFESP, Paulista Sch Med, Dept Ophthalmol & Visual Sci, São Paulo, BrazilFed Univ São Paulo UNIFESP, Paulista Sch Med, Dept Hlth Informat, BR-04023062 São Paulo, BrazilWeb of ScienceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FAPESP: 2012/07343-8FAPESP: 2013/20857-3Hindawi Publishing CorporationUniversidade Federal de São Paulo (UNIFESP)Inst Olhos Renato AmbrosioPaz, Amanda C. da [UNIFESP]Bersanetti, Patricia A. [UNIFESP]Salomao, Marcella Q.Ambrosio, Renato [UNIFESP]Schor, Paulo [UNIFESP]2016-01-24T14:34:57Z2016-01-24T14:34:57Z2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion9application/pdfhttp://dx.doi.org/10.1155/2014/890823Journal of Ophthalmology. New York: Hindawi Publishing Corporation, 9 p., 2014.10.1155/2014/890823WOS000344168700001.pdf2090-004Xhttp://repositorio.unifesp.br/handle/11600/37160WOS:000344168700001engJournal of Ophthalmologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-31T17:31:45Zoai:repositorio.unifesp.br/:11600/37160Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-31T17:31:45Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
title Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
spellingShingle Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
Paz, Amanda C. da [UNIFESP]
title_short Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
title_full Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
title_fullStr Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
title_full_unstemmed Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
title_sort Theoretical Basis, Laboratory Evidence, and Clinical Research of Chemical Surgery of the Cornea: Cross-Linking
author Paz, Amanda C. da [UNIFESP]
author_facet Paz, Amanda C. da [UNIFESP]
Bersanetti, Patricia A. [UNIFESP]
Salomao, Marcella Q.
Ambrosio, Renato [UNIFESP]
Schor, Paulo [UNIFESP]
author_role author
author2 Bersanetti, Patricia A. [UNIFESP]
Salomao, Marcella Q.
Ambrosio, Renato [UNIFESP]
Schor, Paulo [UNIFESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Inst Olhos Renato Ambrosio
dc.contributor.author.fl_str_mv Paz, Amanda C. da [UNIFESP]
Bersanetti, Patricia A. [UNIFESP]
Salomao, Marcella Q.
Ambrosio, Renato [UNIFESP]
Schor, Paulo [UNIFESP]
description Corneal cross-linking (CXL) is increasingly performed in ophthalmology with high success rates for progressive keratoconus and other types of ectasia. Despite being an established procedure, some molecular and clinical aspects still require additional studies. This review presents a critical analysis of some established topics and others that are still controversial. in addition, this review examines new technologies and techniques (transepithelial and ultrafast CXL), uses of corneal CXL including natural products and biomolecules as CXL promoters, and evidence for in vitro and in vivo indirect effectiveness.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
2016-01-24T14:34:57Z
2016-01-24T14:34:57Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1155/2014/890823
Journal of Ophthalmology. New York: Hindawi Publishing Corporation, 9 p., 2014.
10.1155/2014/890823
WOS000344168700001.pdf
2090-004X
http://repositorio.unifesp.br/handle/11600/37160
WOS:000344168700001
url http://dx.doi.org/10.1155/2014/890823
http://repositorio.unifesp.br/handle/11600/37160
identifier_str_mv Journal of Ophthalmology. New York: Hindawi Publishing Corporation, 9 p., 2014.
10.1155/2014/890823
WOS000344168700001.pdf
2090-004X
WOS:000344168700001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Ophthalmology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9
application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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