Efeitos tardios dos praguicidas organoclorados no homem
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
dARK ID: | ark:/48912/001300000jkj5 |
Texto Completo: | http://dx.doi.org/10.1590/S0034-89101998000400011 http://repositorio.unifesp.br/handle/11600/658 |
Resumo: | Available information on organochlorines and the chronic effects of exposure to them are set out. Organochlorinated compounds are the most persistent pesticides and can be found in all ecosystems. Although they are generally efficient in pest control, they are also a potent environment pollutant and can provoke health problems in man. The evidences of the carcinogenic potential of organochlorines are controversial and insufficient, but they have been related to an increase in the incidence of some kinds of tumors, such as leukemia and solid tumors. Reproductive effects, due to anti-androgenic and estrogenic action, on embryonic virilization, the incidence of abortion and the frequency of prematurity, have also been observed. The accumulation of the organochlorines in the adipous tissue is positively correlated to the increase in aging and could be implicated in the development of aging diseases, such as Parkinson's disease. The effects of pesticides on human health have not yet been completely elucidated. Genotoxicity is one of the most serious of the possible harmful effects caused by these compounds and calls for special attention in view of the irreversible nature of the process and to the long latency associated with its manifestation. |
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Efeitos tardios dos praguicidas organoclorados no homemDelayed effects of organochlorine pesticides in manPesticidesLeukemiaPesticide exposurePraguicidasLeucemiaExposição a praguicidasAvailable information on organochlorines and the chronic effects of exposure to them are set out. Organochlorinated compounds are the most persistent pesticides and can be found in all ecosystems. Although they are generally efficient in pest control, they are also a potent environment pollutant and can provoke health problems in man. The evidences of the carcinogenic potential of organochlorines are controversial and insufficient, but they have been related to an increase in the incidence of some kinds of tumors, such as leukemia and solid tumors. Reproductive effects, due to anti-androgenic and estrogenic action, on embryonic virilization, the incidence of abortion and the frequency of prematurity, have also been observed. The accumulation of the organochlorines in the adipous tissue is positively correlated to the increase in aging and could be implicated in the development of aging diseases, such as Parkinson's disease. The effects of pesticides on human health have not yet been completely elucidated. Genotoxicity is one of the most serious of the possible harmful effects caused by these compounds and calls for special attention in view of the irreversible nature of the process and to the long latency associated with its manifestation.Procurou-se relacionar as informações disponíveis sobre os organoclorados e os efeitos crônicos provocados pela exposição. Os compostos organoclorados são os praguicidas mais persistentes já fabricados. Embora sejam geralmente eficientes no controle das pragas, são importantes poluentes ambientais e potenciais causas de problemas de saúde para o homem, tendo sido proibidos ou controlados na maioria dos países. Com poucas exceções, os efeitos tardios desses compostos sobre a saúde humana são difíceis de detectar, em função de dificuldades metodológicas e da extrapolação dos resultados. A genotoxicidade está entre os mais sérios dos possíveis danos causados por esses compostos e merece atenção especial, devido à natureza irreversível do processo. Outro ponto a ser considerado é o aumento na incidência de alterações no desenvolvimento do trato reprodutivo e na fertilidade masculina observada nas últimas décadas provavelmente decorrente do aumento da exposição intra-uterina a compostos estrogênicos e anti-androgênicos, como os organoclorados.Universidade Federal de São Paulo (UNIFESP)Universidade Estadual PaulistaUNIFESP, EPM, São Paulo, BrasilSciELOFaculdade de Saúde Pública da Universidade de São PauloUniversidade Federal de São Paulo (UNIFESP)Universidade Estadual Paulista (UNESP)Nunes, Mônica Vannucci [UNIFESP]Tajara, Eloiza Helena2015-06-14T13:24:46Z2015-06-14T13:24:46Z1998-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion372-382application/pdfhttp://dx.doi.org/10.1590/S0034-89101998000400011Revista de Saúde Pública. Faculdade de Saúde Pública da Universidade de São Paulo, v. 32, n. 4, p. 372-382, 1998.10.1590/S0034-89101998000400011S0034-89101998000400011.pdf0034-8910S0034-89101998000400011http://repositorio.unifesp.br/handle/11600/658ark:/48912/001300000jkj5porRevista de Saúde Públicainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T03:12:10Zoai:repositorio.unifesp.br/:11600/658Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:21:18.805245Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Efeitos tardios dos praguicidas organoclorados no homem Delayed effects of organochlorine pesticides in man |
title |
Efeitos tardios dos praguicidas organoclorados no homem |
spellingShingle |
Efeitos tardios dos praguicidas organoclorados no homem Nunes, Mônica Vannucci [UNIFESP] Pesticides Leukemia Pesticide exposure Praguicidas Leucemia Exposição a praguicidas |
title_short |
Efeitos tardios dos praguicidas organoclorados no homem |
title_full |
Efeitos tardios dos praguicidas organoclorados no homem |
title_fullStr |
Efeitos tardios dos praguicidas organoclorados no homem |
title_full_unstemmed |
Efeitos tardios dos praguicidas organoclorados no homem |
title_sort |
Efeitos tardios dos praguicidas organoclorados no homem |
author |
Nunes, Mônica Vannucci [UNIFESP] |
author_facet |
Nunes, Mônica Vannucci [UNIFESP] Tajara, Eloiza Helena |
author_role |
author |
author2 |
Tajara, Eloiza Helena |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Nunes, Mônica Vannucci [UNIFESP] Tajara, Eloiza Helena |
dc.subject.por.fl_str_mv |
Pesticides Leukemia Pesticide exposure Praguicidas Leucemia Exposição a praguicidas |
topic |
Pesticides Leukemia Pesticide exposure Praguicidas Leucemia Exposição a praguicidas |
description |
Available information on organochlorines and the chronic effects of exposure to them are set out. Organochlorinated compounds are the most persistent pesticides and can be found in all ecosystems. Although they are generally efficient in pest control, they are also a potent environment pollutant and can provoke health problems in man. The evidences of the carcinogenic potential of organochlorines are controversial and insufficient, but they have been related to an increase in the incidence of some kinds of tumors, such as leukemia and solid tumors. Reproductive effects, due to anti-androgenic and estrogenic action, on embryonic virilization, the incidence of abortion and the frequency of prematurity, have also been observed. The accumulation of the organochlorines in the adipous tissue is positively correlated to the increase in aging and could be implicated in the development of aging diseases, such as Parkinson's disease. The effects of pesticides on human health have not yet been completely elucidated. Genotoxicity is one of the most serious of the possible harmful effects caused by these compounds and calls for special attention in view of the irreversible nature of the process and to the long latency associated with its manifestation. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-08-01 2015-06-14T13:24:46Z 2015-06-14T13:24:46Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0034-89101998000400011 Revista de Saúde Pública. Faculdade de Saúde Pública da Universidade de São Paulo, v. 32, n. 4, p. 372-382, 1998. 10.1590/S0034-89101998000400011 S0034-89101998000400011.pdf 0034-8910 S0034-89101998000400011 http://repositorio.unifesp.br/handle/11600/658 |
dc.identifier.dark.fl_str_mv |
ark:/48912/001300000jkj5 |
url |
http://dx.doi.org/10.1590/S0034-89101998000400011 http://repositorio.unifesp.br/handle/11600/658 |
identifier_str_mv |
Revista de Saúde Pública. Faculdade de Saúde Pública da Universidade de São Paulo, v. 32, n. 4, p. 372-382, 1998. 10.1590/S0034-89101998000400011 S0034-89101998000400011.pdf 0034-8910 S0034-89101998000400011 ark:/48912/001300000jkj5 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista de Saúde Pública |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
372-382 application/pdf |
dc.publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
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1818602473224404992 |