Efeitos tardios dos praguicidas organoclorados no homem

Detalhes bibliográficos
Autor(a) principal: Nunes, Mônica Vannucci [UNIFESP]
Data de Publicação: 1998
Outros Autores: Tajara, Eloiza Helena
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
dARK ID: ark:/48912/001300000jkj5
Texto Completo: http://dx.doi.org/10.1590/S0034-89101998000400011
http://repositorio.unifesp.br/handle/11600/658
Resumo: Available information on organochlorines and the chronic effects of exposure to them are set out. Organochlorinated compounds are the most persistent pesticides and can be found in all ecosystems. Although they are generally efficient in pest control, they are also a potent environment pollutant and can provoke health problems in man. The evidences of the carcinogenic potential of organochlorines are controversial and insufficient, but they have been related to an increase in the incidence of some kinds of tumors, such as leukemia and solid tumors. Reproductive effects, due to anti-androgenic and estrogenic action, on embryonic virilization, the incidence of abortion and the frequency of prematurity, have also been observed. The accumulation of the organochlorines in the adipous tissue is positively correlated to the increase in aging and could be implicated in the development of aging diseases, such as Parkinson's disease. The effects of pesticides on human health have not yet been completely elucidated. Genotoxicity is one of the most serious of the possible harmful effects caused by these compounds and calls for special attention in view of the irreversible nature of the process and to the long latency associated with its manifestation.
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spelling Efeitos tardios dos praguicidas organoclorados no homemDelayed effects of organochlorine pesticides in manPesticidesLeukemiaPesticide exposurePraguicidasLeucemiaExposição a praguicidasAvailable information on organochlorines and the chronic effects of exposure to them are set out. Organochlorinated compounds are the most persistent pesticides and can be found in all ecosystems. Although they are generally efficient in pest control, they are also a potent environment pollutant and can provoke health problems in man. The evidences of the carcinogenic potential of organochlorines are controversial and insufficient, but they have been related to an increase in the incidence of some kinds of tumors, such as leukemia and solid tumors. Reproductive effects, due to anti-androgenic and estrogenic action, on embryonic virilization, the incidence of abortion and the frequency of prematurity, have also been observed. The accumulation of the organochlorines in the adipous tissue is positively correlated to the increase in aging and could be implicated in the development of aging diseases, such as Parkinson's disease. The effects of pesticides on human health have not yet been completely elucidated. Genotoxicity is one of the most serious of the possible harmful effects caused by these compounds and calls for special attention in view of the irreversible nature of the process and to the long latency associated with its manifestation.Procurou-se relacionar as informações disponíveis sobre os organoclorados e os efeitos crônicos provocados pela exposição. Os compostos organoclorados são os praguicidas mais persistentes já fabricados. Embora sejam geralmente eficientes no controle das pragas, são importantes poluentes ambientais e potenciais causas de problemas de saúde para o homem, tendo sido proibidos ou controlados na maioria dos países. Com poucas exceções, os efeitos tardios desses compostos sobre a saúde humana são difíceis de detectar, em função de dificuldades metodológicas e da extrapolação dos resultados. A genotoxicidade está entre os mais sérios dos possíveis danos causados por esses compostos e merece atenção especial, devido à natureza irreversível do processo. Outro ponto a ser considerado é o aumento na incidência de alterações no desenvolvimento do trato reprodutivo e na fertilidade masculina observada nas últimas décadas provavelmente decorrente do aumento da exposição intra-uterina a compostos estrogênicos e anti-androgênicos, como os organoclorados.Universidade Federal de São Paulo (UNIFESP)Universidade Estadual PaulistaUNIFESP, EPM, São Paulo, BrasilSciELOFaculdade de Saúde Pública da Universidade de São PauloUniversidade Federal de São Paulo (UNIFESP)Universidade Estadual Paulista (UNESP)Nunes, Mônica Vannucci [UNIFESP]Tajara, Eloiza Helena2015-06-14T13:24:46Z2015-06-14T13:24:46Z1998-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion372-382application/pdfhttp://dx.doi.org/10.1590/S0034-89101998000400011Revista de Saúde Pública. Faculdade de Saúde Pública da Universidade de São Paulo, v. 32, n. 4, p. 372-382, 1998.10.1590/S0034-89101998000400011S0034-89101998000400011.pdf0034-8910S0034-89101998000400011http://repositorio.unifesp.br/handle/11600/658ark:/48912/001300000jkj5porRevista de Saúde Públicainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T03:12:10Zoai:repositorio.unifesp.br/:11600/658Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:21:18.805245Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Efeitos tardios dos praguicidas organoclorados no homem
Delayed effects of organochlorine pesticides in man
title Efeitos tardios dos praguicidas organoclorados no homem
spellingShingle Efeitos tardios dos praguicidas organoclorados no homem
Nunes, Mônica Vannucci [UNIFESP]
Pesticides
Leukemia
Pesticide exposure
Praguicidas
Leucemia
Exposição a praguicidas
title_short Efeitos tardios dos praguicidas organoclorados no homem
title_full Efeitos tardios dos praguicidas organoclorados no homem
title_fullStr Efeitos tardios dos praguicidas organoclorados no homem
title_full_unstemmed Efeitos tardios dos praguicidas organoclorados no homem
title_sort Efeitos tardios dos praguicidas organoclorados no homem
author Nunes, Mônica Vannucci [UNIFESP]
author_facet Nunes, Mônica Vannucci [UNIFESP]
Tajara, Eloiza Helena
author_role author
author2 Tajara, Eloiza Helena
author2_role author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Nunes, Mônica Vannucci [UNIFESP]
Tajara, Eloiza Helena
dc.subject.por.fl_str_mv Pesticides
Leukemia
Pesticide exposure
Praguicidas
Leucemia
Exposição a praguicidas
topic Pesticides
Leukemia
Pesticide exposure
Praguicidas
Leucemia
Exposição a praguicidas
description Available information on organochlorines and the chronic effects of exposure to them are set out. Organochlorinated compounds are the most persistent pesticides and can be found in all ecosystems. Although they are generally efficient in pest control, they are also a potent environment pollutant and can provoke health problems in man. The evidences of the carcinogenic potential of organochlorines are controversial and insufficient, but they have been related to an increase in the incidence of some kinds of tumors, such as leukemia and solid tumors. Reproductive effects, due to anti-androgenic and estrogenic action, on embryonic virilization, the incidence of abortion and the frequency of prematurity, have also been observed. The accumulation of the organochlorines in the adipous tissue is positively correlated to the increase in aging and could be implicated in the development of aging diseases, such as Parkinson's disease. The effects of pesticides on human health have not yet been completely elucidated. Genotoxicity is one of the most serious of the possible harmful effects caused by these compounds and calls for special attention in view of the irreversible nature of the process and to the long latency associated with its manifestation.
publishDate 1998
dc.date.none.fl_str_mv 1998-08-01
2015-06-14T13:24:46Z
2015-06-14T13:24:46Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0034-89101998000400011
Revista de Saúde Pública. Faculdade de Saúde Pública da Universidade de São Paulo, v. 32, n. 4, p. 372-382, 1998.
10.1590/S0034-89101998000400011
S0034-89101998000400011.pdf
0034-8910
S0034-89101998000400011
http://repositorio.unifesp.br/handle/11600/658
dc.identifier.dark.fl_str_mv ark:/48912/001300000jkj5
url http://dx.doi.org/10.1590/S0034-89101998000400011
http://repositorio.unifesp.br/handle/11600/658
identifier_str_mv Revista de Saúde Pública. Faculdade de Saúde Pública da Universidade de São Paulo, v. 32, n. 4, p. 372-382, 1998.
10.1590/S0034-89101998000400011
S0034-89101998000400011.pdf
0034-8910
S0034-89101998000400011
ark:/48912/001300000jkj5
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista de Saúde Pública
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 372-382
application/pdf
dc.publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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