Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes

Detalhes bibliográficos
Autor(a) principal: Lima, Fabricio O.
Data de Publicação: 2016
Outros Autores: Silva, Gisele S. [UNIFESP], Furie, Karen L., Frankel, Michael R., Lev, Michael H., Camargo, Erica C. S., Haussen, Diogo C., Singhal, Aneesh B., Koroshetz, Walter J., Smith, Wade S., Nogueira, Raul G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1161/STROKEAHA.116.013301
https://repositorio.unifesp.br/handle/11600/57489
Resumo: Background and Purpose-Patients with large vessel occlusion strokes (LVOS) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers. However, accurate stroke field triage remains challenging. We aimed to develop a simple field scale to identify LVOS. Methods-The Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scale was based on items of the National Institutes of Health Stroke Scale (NIHSS) with higher predictive value for LVOS and tested in the Screening Technology and Outcomes Project in Stroke (STOPStroke) cohort, in which patients underwent computed tomographic angiography within the first 24 hours of stroke onset. LVOS were defined by total occlusions involving the intracranial internal carotid artery, middle cerebral artery-M1, middle cerebral artery-2, or basilar arteries. Patients with partial, bihemispheric, and anterior+posterior circulation occlusions were excluded. Receiver operating characteristic curve, sensitivity, specificity, positive predictive value, and negative predictive value of FAST-ED were compared with the NIHSS, Rapid Arterial Occlusion Evaluation (RACE) scale, and Cincinnati Prehospital Stroke Severity (CPSS) scale. Results-LVO was detected in 240 of the 727 qualifying patients (33%). FAST-ED had comparable accuracy to predict LVO to the NIHSS and higher accuracy than RACE and CPSS (area under the receiver operating characteristic curve: FAST-ED=0.81 as reference
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spelling Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokescerebrovascular occlusionscalestroke, acute, prehospital emergency caretriageBackground and Purpose-Patients with large vessel occlusion strokes (LVOS) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers. However, accurate stroke field triage remains challenging. We aimed to develop a simple field scale to identify LVOS. Methods-The Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scale was based on items of the National Institutes of Health Stroke Scale (NIHSS) with higher predictive value for LVOS and tested in the Screening Technology and Outcomes Project in Stroke (STOPStroke) cohort, in which patients underwent computed tomographic angiography within the first 24 hours of stroke onset. LVOS were defined by total occlusions involving the intracranial internal carotid artery, middle cerebral artery-M1, middle cerebral artery-2, or basilar arteries. Patients with partial, bihemispheric, and anterior+posterior circulation occlusions were excluded. Receiver operating characteristic curve, sensitivity, specificity, positive predictive value, and negative predictive value of FAST-ED were compared with the NIHSS, Rapid Arterial Occlusion Evaluation (RACE) scale, and Cincinnati Prehospital Stroke Severity (CPSS) scale. Results-LVO was detected in 240 of the 727 qualifying patients (33%). FAST-ED had comparable accuracy to predict LVO to the NIHSS and higher accuracy than RACE and CPSS (area under the receiver operating characteristic curve: FAST-ED=0.81 as referenceNIHSS=0.80, P=0.28RACE=0.77, P=0.02and CPSS=0.75, P=0.002). A FAST-ED >= 4 had sensitivity of 0.60, specificity of 0.89, positive predictive value of 0.72, and negative predictive value of 0.82 versus RACE >= 5 of 0.55, 0.87, 0.68, and 0.79, and CPSS >= 2 of 0.56, 0.85, 0.65, and 0.78, respectively. Conclusions-FAST-ED is a simple scale that if successfully validated in the field, it may be used by medical emergency professionals to identify LVOS in the prehospital setting enabling rapid triage of patients.Univ Fortaleza, Ctr Ciencias Saude, Curso Med, Fortaleza, CE, BrazilUniv Fed Sao Paulo, Dept Neurol, Neurovasc Serv, Sao Paulo, SP, BrazilBrown Univ, Dept Neurol, Providence, RI USAEmory Univ, Sch Med, Grady Mem Hosp, Marcus Stroke & Neurosci Ctr,Neuroendovasc & Neur, Atlanta, GA USAMassachusetts Gen Hosp, Dept Radiol, Boston, MA USAMassachusetts Gen Hosp, Dept Neurol, Stroke Serv, Boston, MA USANINDS, NIH, Bethesda, MD USAUniv Calif San Francisco, Dept Neurol, Neurovasc Serv, San Francisco, CA USAUniv Fed Sao Paulo, Dept Neurol, Neurovasc Serv, Sao Paulo, SP, BrazilWeb of ScienceNIHBiogenBoehringer IngelheimStryker Neurovascular-modestNIH: R01NS051412NIH: P50NS051343NIH: R21NS077442NIH: R21-NS085574NIH: U10NS086729Lippincott Williams & Wilkins2020-08-14T13:44:01Z2020-08-14T13:44:01Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1997-2002application/pdfhttp://dx.doi.org/10.1161/STROKEAHA.116.013301Stroke. Philadelphia, v. 47, n. 8, p. 1997-2002, 2016.10.1161/STROKEAHA.116.013301WOS000380808400017.pdf0039-2499https://repositorio.unifesp.br/handle/11600/57489WOS:000380808400017engStrokePhiladelphiainfo:eu-repo/semantics/openAccessLima, Fabricio O.Silva, Gisele S. [UNIFESP]Furie, Karen L.Frankel, Michael R.Lev, Michael H.Camargo, Erica C. S.Haussen, Diogo C.Singhal, Aneesh B.Koroshetz, Walter J.Smith, Wade S.Nogueira, Raul G.reponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-08T06:32:54Zoai:repositorio.unifesp.br/:11600/57489Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-08T06:32:54Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
title Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
spellingShingle Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
Lima, Fabricio O.
cerebrovascular occlusion
scale
stroke, acute, prehospital emergency care
triage
title_short Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
title_full Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
title_fullStr Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
title_full_unstemmed Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
title_sort Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
author Lima, Fabricio O.
author_facet Lima, Fabricio O.
Silva, Gisele S. [UNIFESP]
Furie, Karen L.
Frankel, Michael R.
Lev, Michael H.
Camargo, Erica C. S.
Haussen, Diogo C.
Singhal, Aneesh B.
Koroshetz, Walter J.
Smith, Wade S.
Nogueira, Raul G.
author_role author
author2 Silva, Gisele S. [UNIFESP]
Furie, Karen L.
Frankel, Michael R.
Lev, Michael H.
Camargo, Erica C. S.
Haussen, Diogo C.
Singhal, Aneesh B.
Koroshetz, Walter J.
Smith, Wade S.
Nogueira, Raul G.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lima, Fabricio O.
Silva, Gisele S. [UNIFESP]
Furie, Karen L.
Frankel, Michael R.
Lev, Michael H.
Camargo, Erica C. S.
Haussen, Diogo C.
Singhal, Aneesh B.
Koroshetz, Walter J.
Smith, Wade S.
Nogueira, Raul G.
dc.subject.por.fl_str_mv cerebrovascular occlusion
scale
stroke, acute, prehospital emergency care
triage
topic cerebrovascular occlusion
scale
stroke, acute, prehospital emergency care
triage
description Background and Purpose-Patients with large vessel occlusion strokes (LVOS) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers. However, accurate stroke field triage remains challenging. We aimed to develop a simple field scale to identify LVOS. Methods-The Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scale was based on items of the National Institutes of Health Stroke Scale (NIHSS) with higher predictive value for LVOS and tested in the Screening Technology and Outcomes Project in Stroke (STOPStroke) cohort, in which patients underwent computed tomographic angiography within the first 24 hours of stroke onset. LVOS were defined by total occlusions involving the intracranial internal carotid artery, middle cerebral artery-M1, middle cerebral artery-2, or basilar arteries. Patients with partial, bihemispheric, and anterior+posterior circulation occlusions were excluded. Receiver operating characteristic curve, sensitivity, specificity, positive predictive value, and negative predictive value of FAST-ED were compared with the NIHSS, Rapid Arterial Occlusion Evaluation (RACE) scale, and Cincinnati Prehospital Stroke Severity (CPSS) scale. Results-LVO was detected in 240 of the 727 qualifying patients (33%). FAST-ED had comparable accuracy to predict LVO to the NIHSS and higher accuracy than RACE and CPSS (area under the receiver operating characteristic curve: FAST-ED=0.81 as reference
publishDate 2016
dc.date.none.fl_str_mv 2016
2020-08-14T13:44:01Z
2020-08-14T13:44:01Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1161/STROKEAHA.116.013301
Stroke. Philadelphia, v. 47, n. 8, p. 1997-2002, 2016.
10.1161/STROKEAHA.116.013301
WOS000380808400017.pdf
0039-2499
https://repositorio.unifesp.br/handle/11600/57489
WOS:000380808400017
url http://dx.doi.org/10.1161/STROKEAHA.116.013301
https://repositorio.unifesp.br/handle/11600/57489
identifier_str_mv Stroke. Philadelphia, v. 47, n. 8, p. 1997-2002, 2016.
10.1161/STROKEAHA.116.013301
WOS000380808400017.pdf
0039-2499
WOS:000380808400017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Stroke
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1997-2002
application/pdf
dc.coverage.none.fl_str_mv Philadelphia
dc.publisher.none.fl_str_mv Lippincott Williams & Wilkins
publisher.none.fl_str_mv Lippincott Williams & Wilkins
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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