Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1161/STROKEAHA.116.013301 https://repositorio.unifesp.br/handle/11600/57489 |
Resumo: | Background and Purpose-Patients with large vessel occlusion strokes (LVOS) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers. However, accurate stroke field triage remains challenging. We aimed to develop a simple field scale to identify LVOS. Methods-The Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scale was based on items of the National Institutes of Health Stroke Scale (NIHSS) with higher predictive value for LVOS and tested in the Screening Technology and Outcomes Project in Stroke (STOPStroke) cohort, in which patients underwent computed tomographic angiography within the first 24 hours of stroke onset. LVOS were defined by total occlusions involving the intracranial internal carotid artery, middle cerebral artery-M1, middle cerebral artery-2, or basilar arteries. Patients with partial, bihemispheric, and anterior+posterior circulation occlusions were excluded. Receiver operating characteristic curve, sensitivity, specificity, positive predictive value, and negative predictive value of FAST-ED were compared with the NIHSS, Rapid Arterial Occlusion Evaluation (RACE) scale, and Cincinnati Prehospital Stroke Severity (CPSS) scale. Results-LVO was detected in 240 of the 727 qualifying patients (33%). FAST-ED had comparable accuracy to predict LVO to the NIHSS and higher accuracy than RACE and CPSS (area under the receiver operating characteristic curve: FAST-ED=0.81 as reference |
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Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokescerebrovascular occlusionscalestroke, acute, prehospital emergency caretriageBackground and Purpose-Patients with large vessel occlusion strokes (LVOS) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers. However, accurate stroke field triage remains challenging. We aimed to develop a simple field scale to identify LVOS. Methods-The Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scale was based on items of the National Institutes of Health Stroke Scale (NIHSS) with higher predictive value for LVOS and tested in the Screening Technology and Outcomes Project in Stroke (STOPStroke) cohort, in which patients underwent computed tomographic angiography within the first 24 hours of stroke onset. LVOS were defined by total occlusions involving the intracranial internal carotid artery, middle cerebral artery-M1, middle cerebral artery-2, or basilar arteries. Patients with partial, bihemispheric, and anterior+posterior circulation occlusions were excluded. Receiver operating characteristic curve, sensitivity, specificity, positive predictive value, and negative predictive value of FAST-ED were compared with the NIHSS, Rapid Arterial Occlusion Evaluation (RACE) scale, and Cincinnati Prehospital Stroke Severity (CPSS) scale. Results-LVO was detected in 240 of the 727 qualifying patients (33%). FAST-ED had comparable accuracy to predict LVO to the NIHSS and higher accuracy than RACE and CPSS (area under the receiver operating characteristic curve: FAST-ED=0.81 as referenceNIHSS=0.80, P=0.28RACE=0.77, P=0.02and CPSS=0.75, P=0.002). A FAST-ED >= 4 had sensitivity of 0.60, specificity of 0.89, positive predictive value of 0.72, and negative predictive value of 0.82 versus RACE >= 5 of 0.55, 0.87, 0.68, and 0.79, and CPSS >= 2 of 0.56, 0.85, 0.65, and 0.78, respectively. Conclusions-FAST-ED is a simple scale that if successfully validated in the field, it may be used by medical emergency professionals to identify LVOS in the prehospital setting enabling rapid triage of patients.Univ Fortaleza, Ctr Ciencias Saude, Curso Med, Fortaleza, CE, BrazilUniv Fed Sao Paulo, Dept Neurol, Neurovasc Serv, Sao Paulo, SP, BrazilBrown Univ, Dept Neurol, Providence, RI USAEmory Univ, Sch Med, Grady Mem Hosp, Marcus Stroke & Neurosci Ctr,Neuroendovasc & Neur, Atlanta, GA USAMassachusetts Gen Hosp, Dept Radiol, Boston, MA USAMassachusetts Gen Hosp, Dept Neurol, Stroke Serv, Boston, MA USANINDS, NIH, Bethesda, MD USAUniv Calif San Francisco, Dept Neurol, Neurovasc Serv, San Francisco, CA USAUniv Fed Sao Paulo, Dept Neurol, Neurovasc Serv, Sao Paulo, SP, BrazilWeb of ScienceNIHBiogenBoehringer IngelheimStryker Neurovascular-modestNIH: R01NS051412NIH: P50NS051343NIH: R21NS077442NIH: R21-NS085574NIH: U10NS086729Lippincott Williams & Wilkins2020-08-14T13:44:01Z2020-08-14T13:44:01Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1997-2002application/pdfhttp://dx.doi.org/10.1161/STROKEAHA.116.013301Stroke. Philadelphia, v. 47, n. 8, p. 1997-2002, 2016.10.1161/STROKEAHA.116.013301WOS000380808400017.pdf0039-2499https://repositorio.unifesp.br/handle/11600/57489WOS:000380808400017engStrokePhiladelphiainfo:eu-repo/semantics/openAccessLima, Fabricio O.Silva, Gisele S. [UNIFESP]Furie, Karen L.Frankel, Michael R.Lev, Michael H.Camargo, Erica C. S.Haussen, Diogo C.Singhal, Aneesh B.Koroshetz, Walter J.Smith, Wade S.Nogueira, Raul G.reponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-08T06:32:54Zoai:repositorio.unifesp.br/:11600/57489Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-08T06:32:54Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes |
title |
Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes |
spellingShingle |
Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes Lima, Fabricio O. cerebrovascular occlusion scale stroke, acute, prehospital emergency care triage |
title_short |
Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes |
title_full |
Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes |
title_fullStr |
Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes |
title_full_unstemmed |
Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes |
title_sort |
Field Assessment Stroke Triage for Emergency Destination A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes |
author |
Lima, Fabricio O. |
author_facet |
Lima, Fabricio O. Silva, Gisele S. [UNIFESP] Furie, Karen L. Frankel, Michael R. Lev, Michael H. Camargo, Erica C. S. Haussen, Diogo C. Singhal, Aneesh B. Koroshetz, Walter J. Smith, Wade S. Nogueira, Raul G. |
author_role |
author |
author2 |
Silva, Gisele S. [UNIFESP] Furie, Karen L. Frankel, Michael R. Lev, Michael H. Camargo, Erica C. S. Haussen, Diogo C. Singhal, Aneesh B. Koroshetz, Walter J. Smith, Wade S. Nogueira, Raul G. |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Lima, Fabricio O. Silva, Gisele S. [UNIFESP] Furie, Karen L. Frankel, Michael R. Lev, Michael H. Camargo, Erica C. S. Haussen, Diogo C. Singhal, Aneesh B. Koroshetz, Walter J. Smith, Wade S. Nogueira, Raul G. |
dc.subject.por.fl_str_mv |
cerebrovascular occlusion scale stroke, acute, prehospital emergency care triage |
topic |
cerebrovascular occlusion scale stroke, acute, prehospital emergency care triage |
description |
Background and Purpose-Patients with large vessel occlusion strokes (LVOS) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers. However, accurate stroke field triage remains challenging. We aimed to develop a simple field scale to identify LVOS. Methods-The Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scale was based on items of the National Institutes of Health Stroke Scale (NIHSS) with higher predictive value for LVOS and tested in the Screening Technology and Outcomes Project in Stroke (STOPStroke) cohort, in which patients underwent computed tomographic angiography within the first 24 hours of stroke onset. LVOS were defined by total occlusions involving the intracranial internal carotid artery, middle cerebral artery-M1, middle cerebral artery-2, or basilar arteries. Patients with partial, bihemispheric, and anterior+posterior circulation occlusions were excluded. Receiver operating characteristic curve, sensitivity, specificity, positive predictive value, and negative predictive value of FAST-ED were compared with the NIHSS, Rapid Arterial Occlusion Evaluation (RACE) scale, and Cincinnati Prehospital Stroke Severity (CPSS) scale. Results-LVO was detected in 240 of the 727 qualifying patients (33%). FAST-ED had comparable accuracy to predict LVO to the NIHSS and higher accuracy than RACE and CPSS (area under the receiver operating characteristic curve: FAST-ED=0.81 as reference |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016 2020-08-14T13:44:01Z 2020-08-14T13:44:01Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1161/STROKEAHA.116.013301 Stroke. Philadelphia, v. 47, n. 8, p. 1997-2002, 2016. 10.1161/STROKEAHA.116.013301 WOS000380808400017.pdf 0039-2499 https://repositorio.unifesp.br/handle/11600/57489 WOS:000380808400017 |
url |
http://dx.doi.org/10.1161/STROKEAHA.116.013301 https://repositorio.unifesp.br/handle/11600/57489 |
identifier_str_mv |
Stroke. Philadelphia, v. 47, n. 8, p. 1997-2002, 2016. 10.1161/STROKEAHA.116.013301 WOS000380808400017.pdf 0039-2499 WOS:000380808400017 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Stroke |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1997-2002 application/pdf |
dc.coverage.none.fl_str_mv |
Philadelphia |
dc.publisher.none.fl_str_mv |
Lippincott Williams & Wilkins |
publisher.none.fl_str_mv |
Lippincott Williams & Wilkins |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268361884827648 |