Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients

Detalhes bibliográficos
Autor(a) principal: Monteiro Junior, Francisco das Chagas [UNIFESP]
Data de Publicação: 2013
Outros Autores: Cunha Junior, Cacionor Pereira da, Muniz Ferreira, Pedro Antonio, Teixeira Nunes, Jose Aldemir, Brito, Ronald Lopes, Barbosa, Jose Bonifacio, Mandarino, Natalia Ribeiro, Lages, Joyce Santos, Salgado Filho, Natalino, Lima, Valter Correia de [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1016/j.repc.2013.04.016
http://repositorio.unifesp.br/handle/11600/37000
Resumo: Introduction and Objectives: Although carotid intima-media thickness (CIMT) is considered a surrogate marker of subclinical atherosclerosis, with known value in risk stratification, its routine use in hypertensive patients is not recommended. the aim of this study was to determine the prevalence of subclinical atherosclerosis through measurement of CIMT and its impact on reclassification of risk in hypertensive patients.Methods: This was a cross-sectional study of 94 middle-aged (56.99 +/- 11.89 years) hypertensive outpatients without overt cardiovascular disease, 68.1% female. All participants underwent clinical examination, biochemical tests, echocardiogram and measurement of CIMT by high-resolution ultrasound.Results: Although the majority of patients were stratified as low (63.5%) or intermediate risk (23%) according to their Framingham score, a high prevalence (75.3%) of increased CIMT was observed in the overall sample, including in the low (61%) and intermediate risk groups (93.8%). CIMT measurement resulted in risk reclassification of 70.31% of the patients, 61% of those at low risk being reclassified as intermediate risk and 93.8% of those at intermediate risk being reclassified as high risk.Conclusion: in these hypertensive outpatients, predominantly middle-aged and female, CIMT measurement revealed a high prevalence of subclinical atherosclerosis and resulted in risk reclassification in the majority of cases. (C) 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L. All rights reserved.
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spelling Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patientsHypertensionCarotid intima-media thicknessRisk assessmentIntroduction and Objectives: Although carotid intima-media thickness (CIMT) is considered a surrogate marker of subclinical atherosclerosis, with known value in risk stratification, its routine use in hypertensive patients is not recommended. the aim of this study was to determine the prevalence of subclinical atherosclerosis through measurement of CIMT and its impact on reclassification of risk in hypertensive patients.Methods: This was a cross-sectional study of 94 middle-aged (56.99 +/- 11.89 years) hypertensive outpatients without overt cardiovascular disease, 68.1% female. All participants underwent clinical examination, biochemical tests, echocardiogram and measurement of CIMT by high-resolution ultrasound.Results: Although the majority of patients were stratified as low (63.5%) or intermediate risk (23%) according to their Framingham score, a high prevalence (75.3%) of increased CIMT was observed in the overall sample, including in the low (61%) and intermediate risk groups (93.8%). CIMT measurement resulted in risk reclassification of 70.31% of the patients, 61% of those at low risk being reclassified as intermediate risk and 93.8% of those at intermediate risk being reclassified as high risk.Conclusion: in these hypertensive outpatients, predominantly middle-aged and female, CIMT measurement revealed a high prevalence of subclinical atherosclerosis and resulted in risk reclassification in the majority of cases. (C) 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L. All rights reserved.Univ Fed Maranhao, Univ Hosp, Serv Cardiol, Sao Luis, Maranhao, BrazilUniversidade Federal de São Paulo, Serv Cardiol, São Paulo, BrazilUniversidade Federal de São Paulo, Serv Cardiol, São Paulo, BrazilWeb of ScienceElsevier B.V.Univ Fed MaranhaoUniversidade Federal de São Paulo (UNIFESP)Monteiro Junior, Francisco das Chagas [UNIFESP]Cunha Junior, Cacionor Pereira daMuniz Ferreira, Pedro AntonioTeixeira Nunes, Jose AldemirBrito, Ronald LopesBarbosa, Jose BonifacioMandarino, Natalia RibeiroLages, Joyce SantosSalgado Filho, NatalinoLima, Valter Correia de [UNIFESP]2016-01-24T14:34:44Z2016-01-24T14:34:44Z2013-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion975-980http://dx.doi.org/10.1016/j.repc.2013.04.016Revista Portuguesa de Cardiologia. Barcelona: Elsevier Doyma Sl, v. 32, n. 12, p. 975-980, 2013.10.1016/j.repc.2013.04.0160870-2551http://repositorio.unifesp.br/handle/11600/37000WOS:000329949300004porRevista Portuguesa de Cardiologiainfo:eu-repo/semantics/openAccesshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2016-01-24T12:34:44Zoai:repositorio.unifesp.br/:11600/37000Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652016-01-24T12:34:44Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
title Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
spellingShingle Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
Monteiro Junior, Francisco das Chagas [UNIFESP]
Hypertension
Carotid intima-media thickness
Risk assessment
title_short Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
title_full Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
title_fullStr Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
title_full_unstemmed Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
title_sort Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
author Monteiro Junior, Francisco das Chagas [UNIFESP]
author_facet Monteiro Junior, Francisco das Chagas [UNIFESP]
Cunha Junior, Cacionor Pereira da
Muniz Ferreira, Pedro Antonio
Teixeira Nunes, Jose Aldemir
Brito, Ronald Lopes
Barbosa, Jose Bonifacio
Mandarino, Natalia Ribeiro
Lages, Joyce Santos
Salgado Filho, Natalino
Lima, Valter Correia de [UNIFESP]
author_role author
author2 Cunha Junior, Cacionor Pereira da
Muniz Ferreira, Pedro Antonio
Teixeira Nunes, Jose Aldemir
Brito, Ronald Lopes
Barbosa, Jose Bonifacio
Mandarino, Natalia Ribeiro
Lages, Joyce Santos
Salgado Filho, Natalino
Lima, Valter Correia de [UNIFESP]
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Univ Fed Maranhao
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Monteiro Junior, Francisco das Chagas [UNIFESP]
Cunha Junior, Cacionor Pereira da
Muniz Ferreira, Pedro Antonio
Teixeira Nunes, Jose Aldemir
Brito, Ronald Lopes
Barbosa, Jose Bonifacio
Mandarino, Natalia Ribeiro
Lages, Joyce Santos
Salgado Filho, Natalino
Lima, Valter Correia de [UNIFESP]
dc.subject.por.fl_str_mv Hypertension
Carotid intima-media thickness
Risk assessment
topic Hypertension
Carotid intima-media thickness
Risk assessment
description Introduction and Objectives: Although carotid intima-media thickness (CIMT) is considered a surrogate marker of subclinical atherosclerosis, with known value in risk stratification, its routine use in hypertensive patients is not recommended. the aim of this study was to determine the prevalence of subclinical atherosclerosis through measurement of CIMT and its impact on reclassification of risk in hypertensive patients.Methods: This was a cross-sectional study of 94 middle-aged (56.99 +/- 11.89 years) hypertensive outpatients without overt cardiovascular disease, 68.1% female. All participants underwent clinical examination, biochemical tests, echocardiogram and measurement of CIMT by high-resolution ultrasound.Results: Although the majority of patients were stratified as low (63.5%) or intermediate risk (23%) according to their Framingham score, a high prevalence (75.3%) of increased CIMT was observed in the overall sample, including in the low (61%) and intermediate risk groups (93.8%). CIMT measurement resulted in risk reclassification of 70.31% of the patients, 61% of those at low risk being reclassified as intermediate risk and 93.8% of those at intermediate risk being reclassified as high risk.Conclusion: in these hypertensive outpatients, predominantly middle-aged and female, CIMT measurement revealed a high prevalence of subclinical atherosclerosis and resulted in risk reclassification in the majority of cases. (C) 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L. All rights reserved.
publishDate 2013
dc.date.none.fl_str_mv 2013-12-01
2016-01-24T14:34:44Z
2016-01-24T14:34:44Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.repc.2013.04.016
Revista Portuguesa de Cardiologia. Barcelona: Elsevier Doyma Sl, v. 32, n. 12, p. 975-980, 2013.
10.1016/j.repc.2013.04.016
0870-2551
http://repositorio.unifesp.br/handle/11600/37000
WOS:000329949300004
url http://dx.doi.org/10.1016/j.repc.2013.04.016
http://repositorio.unifesp.br/handle/11600/37000
identifier_str_mv Revista Portuguesa de Cardiologia. Barcelona: Elsevier Doyma Sl, v. 32, n. 12, p. 975-980, 2013.
10.1016/j.repc.2013.04.016
0870-2551
WOS:000329949300004
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista Portuguesa de Cardiologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
eu_rights_str_mv openAccess
rights_invalid_str_mv http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.format.none.fl_str_mv 975-980
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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