Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1016/j.repc.2013.04.016 http://repositorio.unifesp.br/handle/11600/37000 |
Resumo: | Introduction and Objectives: Although carotid intima-media thickness (CIMT) is considered a surrogate marker of subclinical atherosclerosis, with known value in risk stratification, its routine use in hypertensive patients is not recommended. the aim of this study was to determine the prevalence of subclinical atherosclerosis through measurement of CIMT and its impact on reclassification of risk in hypertensive patients.Methods: This was a cross-sectional study of 94 middle-aged (56.99 +/- 11.89 years) hypertensive outpatients without overt cardiovascular disease, 68.1% female. All participants underwent clinical examination, biochemical tests, echocardiogram and measurement of CIMT by high-resolution ultrasound.Results: Although the majority of patients were stratified as low (63.5%) or intermediate risk (23%) according to their Framingham score, a high prevalence (75.3%) of increased CIMT was observed in the overall sample, including in the low (61%) and intermediate risk groups (93.8%). CIMT measurement resulted in risk reclassification of 70.31% of the patients, 61% of those at low risk being reclassified as intermediate risk and 93.8% of those at intermediate risk being reclassified as high risk.Conclusion: in these hypertensive outpatients, predominantly middle-aged and female, CIMT measurement revealed a high prevalence of subclinical atherosclerosis and resulted in risk reclassification in the majority of cases. (C) 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L. All rights reserved. |
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Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patientsHypertensionCarotid intima-media thicknessRisk assessmentIntroduction and Objectives: Although carotid intima-media thickness (CIMT) is considered a surrogate marker of subclinical atherosclerosis, with known value in risk stratification, its routine use in hypertensive patients is not recommended. the aim of this study was to determine the prevalence of subclinical atherosclerosis through measurement of CIMT and its impact on reclassification of risk in hypertensive patients.Methods: This was a cross-sectional study of 94 middle-aged (56.99 +/- 11.89 years) hypertensive outpatients without overt cardiovascular disease, 68.1% female. All participants underwent clinical examination, biochemical tests, echocardiogram and measurement of CIMT by high-resolution ultrasound.Results: Although the majority of patients were stratified as low (63.5%) or intermediate risk (23%) according to their Framingham score, a high prevalence (75.3%) of increased CIMT was observed in the overall sample, including in the low (61%) and intermediate risk groups (93.8%). CIMT measurement resulted in risk reclassification of 70.31% of the patients, 61% of those at low risk being reclassified as intermediate risk and 93.8% of those at intermediate risk being reclassified as high risk.Conclusion: in these hypertensive outpatients, predominantly middle-aged and female, CIMT measurement revealed a high prevalence of subclinical atherosclerosis and resulted in risk reclassification in the majority of cases. (C) 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L. All rights reserved.Univ Fed Maranhao, Univ Hosp, Serv Cardiol, Sao Luis, Maranhao, BrazilUniversidade Federal de São Paulo, Serv Cardiol, São Paulo, BrazilUniversidade Federal de São Paulo, Serv Cardiol, São Paulo, BrazilWeb of ScienceElsevier B.V.Univ Fed MaranhaoUniversidade Federal de São Paulo (UNIFESP)Monteiro Junior, Francisco das Chagas [UNIFESP]Cunha Junior, Cacionor Pereira daMuniz Ferreira, Pedro AntonioTeixeira Nunes, Jose AldemirBrito, Ronald LopesBarbosa, Jose BonifacioMandarino, Natalia RibeiroLages, Joyce SantosSalgado Filho, NatalinoLima, Valter Correia de [UNIFESP]2016-01-24T14:34:44Z2016-01-24T14:34:44Z2013-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion975-980http://dx.doi.org/10.1016/j.repc.2013.04.016Revista Portuguesa de Cardiologia. Barcelona: Elsevier Doyma Sl, v. 32, n. 12, p. 975-980, 2013.10.1016/j.repc.2013.04.0160870-2551http://repositorio.unifesp.br/handle/11600/37000WOS:000329949300004porRevista Portuguesa de Cardiologiainfo:eu-repo/semantics/openAccesshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2016-01-24T12:34:44Zoai:repositorio.unifesp.br/:11600/37000Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652016-01-24T12:34:44Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients |
title |
Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients |
spellingShingle |
Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients Monteiro Junior, Francisco das Chagas [UNIFESP] Hypertension Carotid intima-media thickness Risk assessment |
title_short |
Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients |
title_full |
Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients |
title_fullStr |
Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients |
title_full_unstemmed |
Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients |
title_sort |
Prevalence of subclinical atherosclerosis and cardiovascular risk reclassification by measure of carotid intima-media thickness in ambulatory hypertensive patients |
author |
Monteiro Junior, Francisco das Chagas [UNIFESP] |
author_facet |
Monteiro Junior, Francisco das Chagas [UNIFESP] Cunha Junior, Cacionor Pereira da Muniz Ferreira, Pedro Antonio Teixeira Nunes, Jose Aldemir Brito, Ronald Lopes Barbosa, Jose Bonifacio Mandarino, Natalia Ribeiro Lages, Joyce Santos Salgado Filho, Natalino Lima, Valter Correia de [UNIFESP] |
author_role |
author |
author2 |
Cunha Junior, Cacionor Pereira da Muniz Ferreira, Pedro Antonio Teixeira Nunes, Jose Aldemir Brito, Ronald Lopes Barbosa, Jose Bonifacio Mandarino, Natalia Ribeiro Lages, Joyce Santos Salgado Filho, Natalino Lima, Valter Correia de [UNIFESP] |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Univ Fed Maranhao Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Monteiro Junior, Francisco das Chagas [UNIFESP] Cunha Junior, Cacionor Pereira da Muniz Ferreira, Pedro Antonio Teixeira Nunes, Jose Aldemir Brito, Ronald Lopes Barbosa, Jose Bonifacio Mandarino, Natalia Ribeiro Lages, Joyce Santos Salgado Filho, Natalino Lima, Valter Correia de [UNIFESP] |
dc.subject.por.fl_str_mv |
Hypertension Carotid intima-media thickness Risk assessment |
topic |
Hypertension Carotid intima-media thickness Risk assessment |
description |
Introduction and Objectives: Although carotid intima-media thickness (CIMT) is considered a surrogate marker of subclinical atherosclerosis, with known value in risk stratification, its routine use in hypertensive patients is not recommended. the aim of this study was to determine the prevalence of subclinical atherosclerosis through measurement of CIMT and its impact on reclassification of risk in hypertensive patients.Methods: This was a cross-sectional study of 94 middle-aged (56.99 +/- 11.89 years) hypertensive outpatients without overt cardiovascular disease, 68.1% female. All participants underwent clinical examination, biochemical tests, echocardiogram and measurement of CIMT by high-resolution ultrasound.Results: Although the majority of patients were stratified as low (63.5%) or intermediate risk (23%) according to their Framingham score, a high prevalence (75.3%) of increased CIMT was observed in the overall sample, including in the low (61%) and intermediate risk groups (93.8%). CIMT measurement resulted in risk reclassification of 70.31% of the patients, 61% of those at low risk being reclassified as intermediate risk and 93.8% of those at intermediate risk being reclassified as high risk.Conclusion: in these hypertensive outpatients, predominantly middle-aged and female, CIMT measurement revealed a high prevalence of subclinical atherosclerosis and resulted in risk reclassification in the majority of cases. (C) 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L. All rights reserved. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-12-01 2016-01-24T14:34:44Z 2016-01-24T14:34:44Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.repc.2013.04.016 Revista Portuguesa de Cardiologia. Barcelona: Elsevier Doyma Sl, v. 32, n. 12, p. 975-980, 2013. 10.1016/j.repc.2013.04.016 0870-2551 http://repositorio.unifesp.br/handle/11600/37000 WOS:000329949300004 |
url |
http://dx.doi.org/10.1016/j.repc.2013.04.016 http://repositorio.unifesp.br/handle/11600/37000 |
identifier_str_mv |
Revista Portuguesa de Cardiologia. Barcelona: Elsevier Doyma Sl, v. 32, n. 12, p. 975-980, 2013. 10.1016/j.repc.2013.04.016 0870-2551 WOS:000329949300004 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista Portuguesa de Cardiologia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy |
dc.format.none.fl_str_mv |
975-980 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
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1814268369079107584 |