Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura

Detalhes bibliográficos
Autor(a) principal: Almeida, Edmilton Pereira De
Data de Publicação: 2007
Outros Autores: Almeida, Maria Antônia Campos [UNIFESP], Amaral, Lígia Menezes Do, Soares Júnior, Cleber, Haddad, Márcia Abudd, Rodrigues, Lúcia Lopes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0103-507X2007000200017
http://repositorio.unifesp.br/handle/11600/3695
Resumo: BACKGROUND AND OBJECTIVES: Amniotic fluid embolism is a rare complication of pregnancy whose physiopathology is not completely known and still not frequently remembered by intensive care physicians and obstetricians. The main aim of this case report was to emphasize the need of better knowledge of this disease by physicians. CASE REPORT: A 15 years old, primigravida, 35th week of gestation was admitted in our intensive care unit (ICU) with a sudden respiratory distress. Soon after admission she was intubated and put on mechanical ventilation. After stabilization she was transferred to the operating room and a cesarean section was undertaken. During the operation, instead of fluid reposition with crystalloids in large amounts, her hemodynamic status deteriorated and it was necessary to use vasoactive drugs. After three days on mechanical ventilation she was successfully weaned and discharged from the intensive care unit (ICU) after 6 days. She and her baby were discharged from hospital on13th day of hospitalization. CONCLUSIONS: Amniotic fluid embolism is a rare and catastrophic complication of pregnancy, at least in its classic presentation. It is characterized by acute respiratory distress, hemodynamic compromise and coagulopathy that occur during or within 30 min after labor. Diagnosis is by exclusion of other conditions of pregnancy or diseases that can be aggravated during pregnancy such as eclampsia, sepsis, pos-partum cardiomyopathy, anaphylaxis, pulmonary thromboembolism, transfusion reactions, anesthetic complications and mitral stenosis. There is growing evidence that we have a spectrum of manifestation which can be more common that in the classic ones. The treatment is supportive of vital functions, such as mechanical ventilation, fluid reposition, vasoactive drugs and fresh frozen plasma as necessary. The intensive care physicians and obstetricians should be aware of this disease in order to make early diagnosis and prompt treatment.
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spelling Embolia pulmonar por líquido amniótico: relato de caso e revisão da literaturaPulmonary amniotic fluid embolism syndrome: case report and literature reviewamniotic fluidembolismpregnancyemboliagestaçãolíquido amnióticoBACKGROUND AND OBJECTIVES: Amniotic fluid embolism is a rare complication of pregnancy whose physiopathology is not completely known and still not frequently remembered by intensive care physicians and obstetricians. The main aim of this case report was to emphasize the need of better knowledge of this disease by physicians. CASE REPORT: A 15 years old, primigravida, 35th week of gestation was admitted in our intensive care unit (ICU) with a sudden respiratory distress. Soon after admission she was intubated and put on mechanical ventilation. After stabilization she was transferred to the operating room and a cesarean section was undertaken. During the operation, instead of fluid reposition with crystalloids in large amounts, her hemodynamic status deteriorated and it was necessary to use vasoactive drugs. After three days on mechanical ventilation she was successfully weaned and discharged from the intensive care unit (ICU) after 6 days. She and her baby were discharged from hospital on13th day of hospitalization. CONCLUSIONS: Amniotic fluid embolism is a rare and catastrophic complication of pregnancy, at least in its classic presentation. It is characterized by acute respiratory distress, hemodynamic compromise and coagulopathy that occur during or within 30 min after labor. Diagnosis is by exclusion of other conditions of pregnancy or diseases that can be aggravated during pregnancy such as eclampsia, sepsis, pos-partum cardiomyopathy, anaphylaxis, pulmonary thromboembolism, transfusion reactions, anesthetic complications and mitral stenosis. There is growing evidence that we have a spectrum of manifestation which can be more common that in the classic ones. The treatment is supportive of vital functions, such as mechanical ventilation, fluid reposition, vasoactive drugs and fresh frozen plasma as necessary. The intensive care physicians and obstetricians should be aware of this disease in order to make early diagnosis and prompt treatment.JUSTIFICATIVA E OBJETIVOS: A embolia pulmonar por líquido amniótico é uma complicação obstétrica rara, freqüentemente fatal, de fisiopatologia ainda não totalmente esclarecida e pouco conhecida pelo intensivista e obstetra. O objetivo deste relato foi enfatizar a necessidade de conhecimento desta entidade clínica e discutir a literatura pertinente de maior relevância. RELATO DO CASO: Paciente com 15 anos, primigesta, 34 semanas de gestação, foi admitida no serviço de emergência para tratamento de início de parto prematuro. Queixava-se de tosse e dispnéia. Ao exame clínico apresentava-se taquipneica (28 irm), ausculta pulmonar normal, sem outras anormalidades. Permaneceu em observação com uso de oxigênio através de máscara facial. Houve agravamento progressivo sendo transferida para a UTI. À admissão na UTI apresentava taquipnéia (28 irm), lúcida, pressão arterial (PA) de 104 x 56 mmHg e pressão arterial média (PAM) de 65 mmHg, SpO2 de 87% com fluxo de oxigênio de 5 L/min. Devido à piora progressiva da mecânica ventilatória foi realizada intubação traqueal e instituída ventilação mecânica com pressão controlada e volume garantido. Radiograma de tórax evidenciou infiltrado pulmonar extenso e bilateral. O painel de coagulação evidenciou importante alargamento do tempo de tromboplastina parcial ativado de 34,7 seg na admissão para 57,4 seg, 10 horas após, com redução progressiva nos dias subsequentes. Foi submetida à cesariana na manhã seguinte. Apresentou importante hipotensão arterial no intra-operatório, apesar de utilização de cristalóides em volume aparentemente adequado, sendo iniciado administração de noradrenalina. Foi extubada no 3º dia, recebendo alta hospitalar 13 dias após a admissão, assintomática. CONCLUSÕES: A embolia por líquido amniótico é uma rara e catastrófica complicação da gestação. A síndrome se caracteriza por um quadro súbito de desconforto ventilatório, hipotensão arterial, sintomatologia neurológica e coagulopatia que se iniciou durante ou em 30 min do trabalho de parto. O diagnóstico é de exclusão de outras afecções mais comuns, tais como eclâmpsia, sepse, miocardiopatia periparto, anafilaxia, tromboembolismo pulmonar, reações transfusionais, complicações anestésicas e estenose mitral, que podem surgir ou agravar-se durante o trabalho de parto. Pode ocorrer durante ou logo após aborto cirúrgico, amniocentese ou colocação de transdutor de pressão na cavidade uterina. O tratamento é o de suporte hemodinâmico, ventilatório e correção dos distúrbios de coagulação. A interrupção imediata da gestação, através de cesariana, parece trazer benefícios para a mãe e concepto. Os intensivistas e obstetras devem estar atentos para esta entidade com o intuito de diagnóstico e tratamento imediatos.Hospital Monte Sinai UTI AdultoUNIFESPAMIBUNIFESPSciELOAssociação de Medicina Intensiva Brasileira - AMIBHospital Monte Sinai UTI AdultoUniversidade Federal de São Paulo (UNIFESP)AMIBAlmeida, Edmilton Pereira DeAlmeida, Maria Antônia Campos [UNIFESP]Amaral, Lígia Menezes DoSoares Júnior, CleberHaddad, Márcia AbuddRodrigues, Lúcia Lopes2015-06-14T13:36:53Z2015-06-14T13:36:53Z2007-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion237-241application/pdfhttp://dx.doi.org/10.1590/S0103-507X2007000200017Revista Brasileira de Terapia Intensiva. Associação de Medicina Intensiva Brasileira - AMIB, v. 19, n. 2, p. 237-241, 2007.10.1590/S0103-507X2007000200017S0103-507X2007000200017.pdf0103-507XS0103-507X2007000200017http://repositorio.unifesp.br/handle/11600/3695porRevista Brasileira de Terapia Intensivainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-28T13:04:17Zoai:repositorio.unifesp.br/:11600/3695Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-28T13:04:17Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura
Pulmonary amniotic fluid embolism syndrome: case report and literature review
title Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura
spellingShingle Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura
Almeida, Edmilton Pereira De
amniotic fluid
embolism
pregnancy
embolia
gestação
líquido amniótico
title_short Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura
title_full Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura
title_fullStr Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura
title_full_unstemmed Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura
title_sort Embolia pulmonar por líquido amniótico: relato de caso e revisão da literatura
author Almeida, Edmilton Pereira De
author_facet Almeida, Edmilton Pereira De
Almeida, Maria Antônia Campos [UNIFESP]
Amaral, Lígia Menezes Do
Soares Júnior, Cleber
Haddad, Márcia Abudd
Rodrigues, Lúcia Lopes
author_role author
author2 Almeida, Maria Antônia Campos [UNIFESP]
Amaral, Lígia Menezes Do
Soares Júnior, Cleber
Haddad, Márcia Abudd
Rodrigues, Lúcia Lopes
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Hospital Monte Sinai UTI Adulto
Universidade Federal de São Paulo (UNIFESP)
AMIB
dc.contributor.author.fl_str_mv Almeida, Edmilton Pereira De
Almeida, Maria Antônia Campos [UNIFESP]
Amaral, Lígia Menezes Do
Soares Júnior, Cleber
Haddad, Márcia Abudd
Rodrigues, Lúcia Lopes
dc.subject.por.fl_str_mv amniotic fluid
embolism
pregnancy
embolia
gestação
líquido amniótico
topic amniotic fluid
embolism
pregnancy
embolia
gestação
líquido amniótico
description BACKGROUND AND OBJECTIVES: Amniotic fluid embolism is a rare complication of pregnancy whose physiopathology is not completely known and still not frequently remembered by intensive care physicians and obstetricians. The main aim of this case report was to emphasize the need of better knowledge of this disease by physicians. CASE REPORT: A 15 years old, primigravida, 35th week of gestation was admitted in our intensive care unit (ICU) with a sudden respiratory distress. Soon after admission she was intubated and put on mechanical ventilation. After stabilization she was transferred to the operating room and a cesarean section was undertaken. During the operation, instead of fluid reposition with crystalloids in large amounts, her hemodynamic status deteriorated and it was necessary to use vasoactive drugs. After three days on mechanical ventilation she was successfully weaned and discharged from the intensive care unit (ICU) after 6 days. She and her baby were discharged from hospital on13th day of hospitalization. CONCLUSIONS: Amniotic fluid embolism is a rare and catastrophic complication of pregnancy, at least in its classic presentation. It is characterized by acute respiratory distress, hemodynamic compromise and coagulopathy that occur during or within 30 min after labor. Diagnosis is by exclusion of other conditions of pregnancy or diseases that can be aggravated during pregnancy such as eclampsia, sepsis, pos-partum cardiomyopathy, anaphylaxis, pulmonary thromboembolism, transfusion reactions, anesthetic complications and mitral stenosis. There is growing evidence that we have a spectrum of manifestation which can be more common that in the classic ones. The treatment is supportive of vital functions, such as mechanical ventilation, fluid reposition, vasoactive drugs and fresh frozen plasma as necessary. The intensive care physicians and obstetricians should be aware of this disease in order to make early diagnosis and prompt treatment.
publishDate 2007
dc.date.none.fl_str_mv 2007-06-01
2015-06-14T13:36:53Z
2015-06-14T13:36:53Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0103-507X2007000200017
Revista Brasileira de Terapia Intensiva. Associação de Medicina Intensiva Brasileira - AMIB, v. 19, n. 2, p. 237-241, 2007.
10.1590/S0103-507X2007000200017
S0103-507X2007000200017.pdf
0103-507X
S0103-507X2007000200017
http://repositorio.unifesp.br/handle/11600/3695
url http://dx.doi.org/10.1590/S0103-507X2007000200017
http://repositorio.unifesp.br/handle/11600/3695
identifier_str_mv Revista Brasileira de Terapia Intensiva. Associação de Medicina Intensiva Brasileira - AMIB, v. 19, n. 2, p. 237-241, 2007.
10.1590/S0103-507X2007000200017
S0103-507X2007000200017.pdf
0103-507X
S0103-507X2007000200017
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista Brasileira de Terapia Intensiva
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 237-241
application/pdf
dc.publisher.none.fl_str_mv Associação de Medicina Intensiva Brasileira - AMIB
publisher.none.fl_str_mv Associação de Medicina Intensiva Brasileira - AMIB
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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