Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions
Autor(a) principal: | |
---|---|
Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/31762 http://dx.doi.org/10.1684/epd.2009.0264 |
Resumo: | Background. Describe an ictal EEG pattern of paradoxical lateralization in children with unilateral encephaloclastic hemispheric lesion acquired early in life. Methods. of 68 children who underwent hemispherectomy during 2003-2005, scalp video-EEG and brain MRI of six children with an ictal scalp EEG pattern discordant to the clinical and imaging data were reanalyzed. Medical charts were reviewed for clinical findings and seizure outcome. Results. Age of seizure onset was 1 day-4 years. the destructive MRI lesion was an ischemic stroke in 2, a post-infectious encephalomalacia in 2, and a perinatal trauma and hemiconvulsive-hemiplegic syndrome in one patient each. Ictal EEG pattern was characterized by prominent ictal rhythms with either 3-7 Hz spike and wave complexes or beta frequency sharp waves (paroxysmal fast) over the unaffected (contralesional) hemisphere. Scalp video-EEG was discordant, however, other findings of motor deficits (hemiparesis; five severe, one mild), seizure semiology (4/6), interictal EEG abnormalities (3/6), and unilateral burden of MRI lesion guided the decision for hemispherectomy. After 12-39 months of post-surgery follow up, five of six patients were seizure free and one has brief staring spells. Conclusion. We describe a paradoxical lateralization of the EEG to the good hemisphere in children with unihemispheric encephaloclastic lesions. This EEG pattern is compatible with seizure free outcome after surgery, provided other clinical findings and tests are concordant with origin from the abnormal hemisphere. |
id |
UFSP_ce2533d1e8f41478e22c9d827cc2e8b1 |
---|---|
oai_identifier_str |
oai:repositorio.unifesp.br:11600/31762 |
network_acronym_str |
UFSP |
network_name_str |
Repositório Institucional da UNIFESP |
repository_id_str |
3465 |
spelling |
Garzon, Eliana [UNIFESP]Gupta, AjayBingaman, WilliamSakamoto, Americo C. [UNIFESP]Luders, HansCleveland Clin FdnUniversidade Federal de São Paulo (UNIFESP)Univ Hosp Cleveland2016-01-24T13:58:39Z2016-01-24T13:58:39Z2009-09-01Epileptic Disorders. Montrouge: John Libbey Eurotext Ltd, v. 11, n. 3, p. 215-221, 2009.1294-9361http://repositorio.unifesp.br/handle/11600/31762http://dx.doi.org/10.1684/epd.2009.026410.1684/epd.2009.0264WOS:000270687600004Background. Describe an ictal EEG pattern of paradoxical lateralization in children with unilateral encephaloclastic hemispheric lesion acquired early in life. Methods. of 68 children who underwent hemispherectomy during 2003-2005, scalp video-EEG and brain MRI of six children with an ictal scalp EEG pattern discordant to the clinical and imaging data were reanalyzed. Medical charts were reviewed for clinical findings and seizure outcome. Results. Age of seizure onset was 1 day-4 years. the destructive MRI lesion was an ischemic stroke in 2, a post-infectious encephalomalacia in 2, and a perinatal trauma and hemiconvulsive-hemiplegic syndrome in one patient each. Ictal EEG pattern was characterized by prominent ictal rhythms with either 3-7 Hz spike and wave complexes or beta frequency sharp waves (paroxysmal fast) over the unaffected (contralesional) hemisphere. Scalp video-EEG was discordant, however, other findings of motor deficits (hemiparesis; five severe, one mild), seizure semiology (4/6), interictal EEG abnormalities (3/6), and unilateral burden of MRI lesion guided the decision for hemispherectomy. After 12-39 months of post-surgery follow up, five of six patients were seizure free and one has brief staring spells. Conclusion. We describe a paradoxical lateralization of the EEG to the good hemisphere in children with unihemispheric encephaloclastic lesions. This EEG pattern is compatible with seizure free outcome after surgery, provided other clinical findings and tests are concordant with origin from the abnormal hemisphere.Cleveland Clin Fdn, Neurol Inst, Epilepsy Ctr, Cleveland, OH 44195 USAUniversidade Federal de São Paulo, São Paulo, BrazilUniv Hosp Cleveland, Epilepsy Ctr, Cleveland, OH 44106 USAUniversidade Federal de São Paulo, EPM, São Paulo, BrazilWeb of Science215-221engJohn Libbey Eurotext LtdEpileptic Disordersepilepsy surgeryEEGpediatric epilepsyvideo-EEG in epilepsyParadoxical ictal EEG lateralization in children with unilateral encephaloclastic lesionsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/317622022-06-02 09:02:13.514metadata only accessoai:repositorio.unifesp.br:11600/31762Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:13:22.302652Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions |
title |
Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions |
spellingShingle |
Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions Garzon, Eliana [UNIFESP] epilepsy surgery EEG pediatric epilepsy video-EEG in epilepsy |
title_short |
Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions |
title_full |
Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions |
title_fullStr |
Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions |
title_full_unstemmed |
Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions |
title_sort |
Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions |
author |
Garzon, Eliana [UNIFESP] |
author_facet |
Garzon, Eliana [UNIFESP] Gupta, Ajay Bingaman, William Sakamoto, Americo C. [UNIFESP] Luders, Hans |
author_role |
author |
author2 |
Gupta, Ajay Bingaman, William Sakamoto, Americo C. [UNIFESP] Luders, Hans |
author2_role |
author author author author |
dc.contributor.institution.none.fl_str_mv |
Cleveland Clin Fdn Universidade Federal de São Paulo (UNIFESP) Univ Hosp Cleveland |
dc.contributor.author.fl_str_mv |
Garzon, Eliana [UNIFESP] Gupta, Ajay Bingaman, William Sakamoto, Americo C. [UNIFESP] Luders, Hans |
dc.subject.eng.fl_str_mv |
epilepsy surgery EEG pediatric epilepsy video-EEG in epilepsy |
topic |
epilepsy surgery EEG pediatric epilepsy video-EEG in epilepsy |
description |
Background. Describe an ictal EEG pattern of paradoxical lateralization in children with unilateral encephaloclastic hemispheric lesion acquired early in life. Methods. of 68 children who underwent hemispherectomy during 2003-2005, scalp video-EEG and brain MRI of six children with an ictal scalp EEG pattern discordant to the clinical and imaging data were reanalyzed. Medical charts were reviewed for clinical findings and seizure outcome. Results. Age of seizure onset was 1 day-4 years. the destructive MRI lesion was an ischemic stroke in 2, a post-infectious encephalomalacia in 2, and a perinatal trauma and hemiconvulsive-hemiplegic syndrome in one patient each. Ictal EEG pattern was characterized by prominent ictal rhythms with either 3-7 Hz spike and wave complexes or beta frequency sharp waves (paroxysmal fast) over the unaffected (contralesional) hemisphere. Scalp video-EEG was discordant, however, other findings of motor deficits (hemiparesis; five severe, one mild), seizure semiology (4/6), interictal EEG abnormalities (3/6), and unilateral burden of MRI lesion guided the decision for hemispherectomy. After 12-39 months of post-surgery follow up, five of six patients were seizure free and one has brief staring spells. Conclusion. We describe a paradoxical lateralization of the EEG to the good hemisphere in children with unihemispheric encephaloclastic lesions. This EEG pattern is compatible with seizure free outcome after surgery, provided other clinical findings and tests are concordant with origin from the abnormal hemisphere. |
publishDate |
2009 |
dc.date.issued.fl_str_mv |
2009-09-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T13:58:39Z |
dc.date.available.fl_str_mv |
2016-01-24T13:58:39Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Epileptic Disorders. Montrouge: John Libbey Eurotext Ltd, v. 11, n. 3, p. 215-221, 2009. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/31762 http://dx.doi.org/10.1684/epd.2009.0264 |
dc.identifier.issn.none.fl_str_mv |
1294-9361 |
dc.identifier.doi.none.fl_str_mv |
10.1684/epd.2009.0264 |
dc.identifier.wos.none.fl_str_mv |
WOS:000270687600004 |
identifier_str_mv |
Epileptic Disorders. Montrouge: John Libbey Eurotext Ltd, v. 11, n. 3, p. 215-221, 2009. 1294-9361 10.1684/epd.2009.0264 WOS:000270687600004 |
url |
http://repositorio.unifesp.br/handle/11600/31762 http://dx.doi.org/10.1684/epd.2009.0264 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Epileptic Disorders |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
215-221 |
dc.publisher.none.fl_str_mv |
John Libbey Eurotext Ltd |
publisher.none.fl_str_mv |
John Libbey Eurotext Ltd |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
_version_ |
1783460264227635200 |