Moyamoya disease: report of three cases in Brazilian patients

• Autor(a) principal: Franco, Clélia Maria Ribeiro
• Data de Publicação: 1999
• Outros Autores: Fukujima, Marcia Maiumi [UNIFESP], Oliveira, Roberto de Magalhães Carneiro de, Gabbai, Alberto Alain [UNIFESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0004-282X1999000300005; http://repositorio.unifesp.br/handle/11600/785
• topic: moyamoya disease; adult; chronic occlusive cerebrovascular disorder; stroke; doença de moyamoya; adulto; doença cerebrovascular; acidente vascular cerebral

Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease of unknown etiology reported mainly in the Japanese. Most cases occur in children. The disease is rare in non-Oriental adults manifesting itself mostly as intracerebral hemorrhages. We describe MMD in 2 non-Oriental young adults and one adolescent that developed cerebral infarctions. The adults were medicated with aspirin and no medication was given to the adolescent. All patients did not deteriorate in a follow-up period from 1 to 4 years. Although rare, MMD is an important cause of stroke in young individuals and may well be underreported: only 18 patients have been reported till 1997 in Brazil. Neurologists should include MMD in differential diagnosis of ischemic and hemorrhagic strokes in young adults.