Depression during gestation in adolescent mothers interferes with neonatal neurobehavior
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/8020 http://dx.doi.org/10.1590/1516-4446-2012-0855 |
Resumo: | Objective: To compare the neurobehavior of neonates born to adolescent mothers with and without depression during gestation. Methods: This prospective cross-sectional study included healthy term neonates born to adolescent mothers with untreated depression during gestation, without exposure to legal or illicit drugs, and compared them with infants born to adolescent mothers without psychiatric disorders. Maternal psychiatric diagnoses were assessed by the Composite International Diagnostic Interview (CIDI 2.1) and neonatal neurobehavior by the Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS) at 24 to 72 hours of life. Neurobehavioral outcomes were analyzed by ANOVA adjusted for confounders. Results: 37 infants born to mothers with depression during gestation were compared to 332 infants born to mothers without psychiatric disorders. Infants of mothers with depression had smaller head circumferences. Significant interactions of maternal depression and male gender, gestational age > 40 weeks, regional anesthesia during delivery, vaginal delivery, and infant head circumference ≥ 34 cm were found. Worse performance was noted in the following neonatal neurobehavioral parameters: arousal, excitability, lethargy, hypotonicity, and signs of stress and abstinence. Conclusion: Infants born to adolescent mothers with depression exhibit some behavioral changes in the first days of life. These changes are associated with infant sex, gestational age, type of anesthesia, mode of delivery, and head circumference. |
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Barros, Marina Carvalho de Moraes [UNIFESP]Mitsuhiro, Sandro Sendin [UNIFESP]Chalem, ElisaLaranjeira, Ronaldo [UNIFESP]Guinsburg, Ruth [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2015-06-14T13:45:41Z2015-06-14T13:45:41Z2013-12-01Revista Brasileira de Psiquiatria. Associação Brasileira de Psiquiatria - ABP, v. 35, n. 4, p. 353-359, 2013.1516-4446http://repositorio.unifesp.br/handle/11600/8020http://dx.doi.org/10.1590/1516-4446-2012-0855S1516-44462013000400353.pdfS1516-4446201300040035310.1590/1516-4446-2012-0855Objective: To compare the neurobehavior of neonates born to adolescent mothers with and without depression during gestation. Methods: This prospective cross-sectional study included healthy term neonates born to adolescent mothers with untreated depression during gestation, without exposure to legal or illicit drugs, and compared them with infants born to adolescent mothers without psychiatric disorders. Maternal psychiatric diagnoses were assessed by the Composite International Diagnostic Interview (CIDI 2.1) and neonatal neurobehavior by the Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS) at 24 to 72 hours of life. Neurobehavioral outcomes were analyzed by ANOVA adjusted for confounders. Results: 37 infants born to mothers with depression during gestation were compared to 332 infants born to mothers without psychiatric disorders. Infants of mothers with depression had smaller head circumferences. Significant interactions of maternal depression and male gender, gestational age > 40 weeks, regional anesthesia during delivery, vaginal delivery, and infant head circumference ≥ 34 cm were found. Worse performance was noted in the following neonatal neurobehavioral parameters: arousal, excitability, lethargy, hypotonicity, and signs of stress and abstinence. Conclusion: Infants born to adolescent mothers with depression exhibit some behavioral changes in the first days of life. These changes are associated with infant sex, gestational age, type of anesthesia, mode of delivery, and head circumference.Universidade Federal de São Paulo (UNIFESP) - Escola Paulista de Medicina (UNIFESP-EPM) Department of Pediatrics Division of Neonatal MedicineUNIFESP and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) National Science and Technology Institute for Policies on Alcohol and Drugs (INPAD)UNIFESP-EPM Research Unit on Alcohol and Other DrugsUNIFESP-EPM Department of PsychiatryUNIFESP, - Escola Paulista de Medicina (UNIFESP-EPM) Department of Pediatrics Division of Neonatal MedicineUNIFESP, and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) National Science and Technology Institute for Policies on Alcohol and Drugs (INPAD)UNIFESP, EPM Research Unit on Alcohol and Other DrugsUNIFESP, EPM Department of PsychiatrySciELO353-359engAssociação Brasileira de Psiquiatria - ABPRevista Brasileira de PsiquiatriaDepressive disorderpregnancy in adolescenceinfant behaviorDepression during gestation in adolescent mothers interferes with neonatal neurobehaviorinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1516-44462013000400353.pdfapplication/pdf75961${dspace.ui.url}/bitstream/11600/8020/1/S1516-44462013000400353.pdf17599815479468d22ca5af512bd03905MD51open accessTEXTS1516-44462013000400353.pdf.txtS1516-44462013000400353.pdf.txtExtracted texttext/plain37789${dspace.ui.url}/bitstream/11600/8020/30/S1516-44462013000400353.pdf.txt5ad51dd6b9d34b0b83f3764f1c59f513MD530open accessTHUMBNAILS1516-44462013000400353.pdf.jpgS1516-44462013000400353.pdf.jpgIM Thumbnailimage/jpeg6890${dspace.ui.url}/bitstream/11600/8020/32/S1516-44462013000400353.pdf.jpg160c1a13304a299c9b2319aff6c99e53MD532open access11600/80202023-06-05 20:22:49.409open accessoai:repositorio.unifesp.br:11600/8020Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-06-05T23:22:49Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Depression during gestation in adolescent mothers interferes with neonatal neurobehavior |
title |
Depression during gestation in adolescent mothers interferes with neonatal neurobehavior |
spellingShingle |
Depression during gestation in adolescent mothers interferes with neonatal neurobehavior Barros, Marina Carvalho de Moraes [UNIFESP] Depressive disorder pregnancy in adolescence infant behavior |
title_short |
Depression during gestation in adolescent mothers interferes with neonatal neurobehavior |
title_full |
Depression during gestation in adolescent mothers interferes with neonatal neurobehavior |
title_fullStr |
Depression during gestation in adolescent mothers interferes with neonatal neurobehavior |
title_full_unstemmed |
Depression during gestation in adolescent mothers interferes with neonatal neurobehavior |
title_sort |
Depression during gestation in adolescent mothers interferes with neonatal neurobehavior |
author |
Barros, Marina Carvalho de Moraes [UNIFESP] |
author_facet |
Barros, Marina Carvalho de Moraes [UNIFESP] Mitsuhiro, Sandro Sendin [UNIFESP] Chalem, Elisa Laranjeira, Ronaldo [UNIFESP] Guinsburg, Ruth [UNIFESP] |
author_role |
author |
author2 |
Mitsuhiro, Sandro Sendin [UNIFESP] Chalem, Elisa Laranjeira, Ronaldo [UNIFESP] Guinsburg, Ruth [UNIFESP] |
author2_role |
author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Barros, Marina Carvalho de Moraes [UNIFESP] Mitsuhiro, Sandro Sendin [UNIFESP] Chalem, Elisa Laranjeira, Ronaldo [UNIFESP] Guinsburg, Ruth [UNIFESP] |
dc.subject.eng.fl_str_mv |
Depressive disorder pregnancy in adolescence infant behavior |
topic |
Depressive disorder pregnancy in adolescence infant behavior |
description |
Objective: To compare the neurobehavior of neonates born to adolescent mothers with and without depression during gestation. Methods: This prospective cross-sectional study included healthy term neonates born to adolescent mothers with untreated depression during gestation, without exposure to legal or illicit drugs, and compared them with infants born to adolescent mothers without psychiatric disorders. Maternal psychiatric diagnoses were assessed by the Composite International Diagnostic Interview (CIDI 2.1) and neonatal neurobehavior by the Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS) at 24 to 72 hours of life. Neurobehavioral outcomes were analyzed by ANOVA adjusted for confounders. Results: 37 infants born to mothers with depression during gestation were compared to 332 infants born to mothers without psychiatric disorders. Infants of mothers with depression had smaller head circumferences. Significant interactions of maternal depression and male gender, gestational age > 40 weeks, regional anesthesia during delivery, vaginal delivery, and infant head circumference ≥ 34 cm were found. Worse performance was noted in the following neonatal neurobehavioral parameters: arousal, excitability, lethargy, hypotonicity, and signs of stress and abstinence. Conclusion: Infants born to adolescent mothers with depression exhibit some behavioral changes in the first days of life. These changes are associated with infant sex, gestational age, type of anesthesia, mode of delivery, and head circumference. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-12-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:45:41Z |
dc.date.available.fl_str_mv |
2015-06-14T13:45:41Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
Revista Brasileira de Psiquiatria. Associação Brasileira de Psiquiatria - ABP, v. 35, n. 4, p. 353-359, 2013. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/8020 http://dx.doi.org/10.1590/1516-4446-2012-0855 |
dc.identifier.issn.none.fl_str_mv |
1516-4446 |
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S1516-44462013000400353.pdf |
dc.identifier.scielo.none.fl_str_mv |
S1516-44462013000400353 |
dc.identifier.doi.none.fl_str_mv |
10.1590/1516-4446-2012-0855 |
identifier_str_mv |
Revista Brasileira de Psiquiatria. Associação Brasileira de Psiquiatria - ABP, v. 35, n. 4, p. 353-359, 2013. 1516-4446 S1516-44462013000400353.pdf S1516-44462013000400353 10.1590/1516-4446-2012-0855 |
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http://repositorio.unifesp.br/handle/11600/8020 http://dx.doi.org/10.1590/1516-4446-2012-0855 |
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Revista Brasileira de Psiquiatria |
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Associação Brasileira de Psiquiatria - ABP |
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Associação Brasileira de Psiquiatria - ABP |
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