Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors
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Publication Date: | 2016 |
Other Authors: | , , , , , , , , |
Format: | Article |
Language: | eng |
Source: | Repositório Institucional da UNIFESP |
Download full: | https://repositorio.unifesp.br/handle/11600/57784 http://dx.doi.org/10.1016/j.marpolbul.2016.01.025 |
Summary: | The goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA. (C) 2016 Elsevier Ltd. All rights reserved. |
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Gusso-Choueri, Paloma KachelChoueri, Rodrigo Brasil [UNIFESP]Santos, Gustavo Souzade Araujo, Giuliana SeraphimFeitosa Cruz, Ana CarolinaStremel, Tatianade Campos, Sandro XavierCestari, Marta MargareteOliveira Ribeiro, Ciro Albertode Sousa Abessa, Denis Moledo2020-08-21T16:59:51Z2020-08-21T16:59:51Z2016Marine Pollution Bulletin. Oxford, v. 104, n. 43497, p. 229-239, 2016.0025-326Xhttps://repositorio.unifesp.br/handle/11600/57784http://dx.doi.org/10.1016/j.marpolbul.2016.01.02510.1016/j.marpolbul.2016.01.025WOS:000374198100039The goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA. (C) 2016 Elsevier Ltd. All rights reserved.National Council for Scientific and Technological Development (CNPq)Sao Paulo Research Foundation (FAPESP)Brazilian Aquatic Research Foundation (FUNDESPA)Brazilian Commission for the Improvement of Higher Education Personnel in Brazil (CAPES)CNPqFed Univ Parana UFPR, Grad Program Ecol & Conservat, CP 19031, BR-81531990 Curitiba, Parana, BrazilFed Univ Parana UFPR, Dept Cellular Biol, Cellular Toxicol Lab, CP19031, BR-81531990 Curitiba, Parana, BrazilSao Paulo State Univ, Lab Study Aquat Pollut & Ecotoxicol NEPEA, Sao Vicente Campus UNESP Campus Litoral Paulista, BR-11330900 Sao Vicente, SP, BrazilUniv Fed Sao Paulo, Dept Marine Sci, Santos Campus UNIFESP Santos, BR-11030490 Santos, SP, BrazilFed Univ Parana UFPR, Dept Genet, BR-81531990 Curitiba, Parana, BrazilUniv Sao Paulo IOUSP, Inst Oceanog, Praca Oceanog 191, BR-05508120 Sao Paulo, SP, BrazilUniv Estadual Ponta Grossa, Res Grp Environm & Sanit Analyt Chem QAAS, Av Gen Carlos Cavalcanti 4748, BR-84030900 Ponta Grossa, BrazilUniv Fed Sao Paulo, Dept Marine Sci, Santos Campus UNIFESP Santos, BR-11030490 Santos, SP, BrazilCNPq: 479899/2013-4FAPESP: 2009/52762-6CNPq: 308649/2011-7CNPq: 311609/2014-7Web of Science229-239engPergamon-Elsevier Science LtdMarine Pollution BulletinEstuaryWeight of evidenceEnvironmental quality assessmentGenotoxicityBiomarkersMultivariate approachAssessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressorsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleOxford1041/fevinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/577842021-08-09 21:27:00.615metadata only accessoai:repositorio.unifesp.br:11600/57784Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:18:15.663905Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
spellingShingle |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors Gusso-Choueri, Paloma Kachel Estuary Weight of evidence Environmental quality assessment Genotoxicity Biomarkers Multivariate approach |
title_short |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title_full |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title_fullStr |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title_full_unstemmed |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title_sort |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
author |
Gusso-Choueri, Paloma Kachel |
author_facet |
Gusso-Choueri, Paloma Kachel Choueri, Rodrigo Brasil [UNIFESP] Santos, Gustavo Souza de Araujo, Giuliana Seraphim Feitosa Cruz, Ana Carolina Stremel, Tatiana de Campos, Sandro Xavier Cestari, Marta Margarete Oliveira Ribeiro, Ciro Alberto de Sousa Abessa, Denis Moledo |
author_role |
author |
author2 |
Choueri, Rodrigo Brasil [UNIFESP] Santos, Gustavo Souza de Araujo, Giuliana Seraphim Feitosa Cruz, Ana Carolina Stremel, Tatiana de Campos, Sandro Xavier Cestari, Marta Margarete Oliveira Ribeiro, Ciro Alberto de Sousa Abessa, Denis Moledo |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Gusso-Choueri, Paloma Kachel Choueri, Rodrigo Brasil [UNIFESP] Santos, Gustavo Souza de Araujo, Giuliana Seraphim Feitosa Cruz, Ana Carolina Stremel, Tatiana de Campos, Sandro Xavier Cestari, Marta Margarete Oliveira Ribeiro, Ciro Alberto de Sousa Abessa, Denis Moledo |
dc.subject.eng.fl_str_mv |
Estuary Weight of evidence Environmental quality assessment Genotoxicity Biomarkers Multivariate approach |
topic |
Estuary Weight of evidence Environmental quality assessment Genotoxicity Biomarkers Multivariate approach |
description |
The goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA. (C) 2016 Elsevier Ltd. All rights reserved. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2020-08-21T16:59:51Z |
dc.date.available.fl_str_mv |
2020-08-21T16:59:51Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Marine Pollution Bulletin. Oxford, v. 104, n. 43497, p. 229-239, 2016. |
dc.identifier.uri.fl_str_mv |
https://repositorio.unifesp.br/handle/11600/57784 http://dx.doi.org/10.1016/j.marpolbul.2016.01.025 |
dc.identifier.issn.none.fl_str_mv |
0025-326X |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.marpolbul.2016.01.025 |
dc.identifier.wos.none.fl_str_mv |
WOS:000374198100039 |
identifier_str_mv |
Marine Pollution Bulletin. Oxford, v. 104, n. 43497, p. 229-239, 2016. 0025-326X 10.1016/j.marpolbul.2016.01.025 WOS:000374198100039 |
url |
https://repositorio.unifesp.br/handle/11600/57784 http://dx.doi.org/10.1016/j.marpolbul.2016.01.025 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Marine Pollution Bulletin |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
229-239 |
dc.coverage.none.fl_str_mv |
Oxford |
dc.publisher.none.fl_str_mv |
Pergamon-Elsevier Science Ltd |
publisher.none.fl_str_mv |
Pergamon-Elsevier Science Ltd |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
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1783460274221613056 |