Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors
Main Author: | |
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Publication Date: | 2016 |
Other Authors: | , , , , , , , , |
Format: | Article |
Language: | eng |
Source: | Repositório Institucional da UNESP |
Download full: | http://dx.doi.org/10.1016/j.marpolbul.2016.01.025 http://hdl.handle.net/11449/172462 |
Summary: | The goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA. |
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Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressorsBiomarkersEnvironmental quality assessmentEstuaryGenotoxicityMultivariate approachWeight of evidenceThe goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA.Graduate Program in Ecology and Conservation Federal University of Paraná (UFPR), CP 19031Cellular Toxicology Laboratory Department of Cellular Biology Federal University of Paraná (UFPR), CP19031Laboratory for the Study of Aquatic Pollution and Ecotoxicology (NEPEA) São Paulo State University Sao Vicente Campus (UNESP Campus do Litoral Paulista), Praca Infante Dom Henrique, s/nDepartment of Marine Sciences Federal University of São Paulo Santos Campus (UNIFESP - Santos), Av. Almirante Saldanha da Gama, 89Genetics Department Federal University of Paraná (UFPR)Institute of Oceanography University of São Paulo (IOUSP), Praça do Oceanográfico, 191Research Group on Environmental and Sanitary Analytical Chemistry (QAAS) Ponta Grossa State University, Av. General Carlos Cavalcanti, 4748Laboratory for the Study of Aquatic Pollution and Ecotoxicology (NEPEA) São Paulo State University Sao Vicente Campus (UNESP Campus do Litoral Paulista), Praca Infante Dom Henrique, s/nUniversidade Federal do Paraná (UFPR)Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Ponta Grossa State UniversityGusso-Choueri, Paloma Kachel [UNESP]Choueri, Rodrigo BrasilSantos, Gustavo Souzade Araújo, Giuliana Seraphim [UNESP]Cruz, Ana Carolina Feitosa [UNESP]Stremel, Tatianade Campos, Sandro XavierCestari, Marta MargareteRibeiro, Ciro Alberto Oliveirade Sousa Abessa, Denis Moledo [UNESP]2018-12-11T17:00:27Z2018-12-11T17:00:27Z2016-03-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article229-239application/pdfhttp://dx.doi.org/10.1016/j.marpolbul.2016.01.025Marine Pollution Bulletin, v. 104, n. 1-2, p. 229-239, 2016.1879-33630025-326Xhttp://hdl.handle.net/11449/17246210.1016/j.marpolbul.2016.01.0252-s2.0-849555668392-s2.0-84955566839.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMarine Pollution Bulletininfo:eu-repo/semantics/openAccess2023-10-25T06:05:30Zoai:repositorio.unesp.br:11449/172462Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-25T06:05:30Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
spellingShingle |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors Gusso-Choueri, Paloma Kachel [UNESP] Biomarkers Environmental quality assessment Estuary Genotoxicity Multivariate approach Weight of evidence |
title_short |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title_full |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title_fullStr |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title_full_unstemmed |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
title_sort |
Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors |
author |
Gusso-Choueri, Paloma Kachel [UNESP] |
author_facet |
Gusso-Choueri, Paloma Kachel [UNESP] Choueri, Rodrigo Brasil Santos, Gustavo Souza de Araújo, Giuliana Seraphim [UNESP] Cruz, Ana Carolina Feitosa [UNESP] Stremel, Tatiana de Campos, Sandro Xavier Cestari, Marta Margarete Ribeiro, Ciro Alberto Oliveira de Sousa Abessa, Denis Moledo [UNESP] |
author_role |
author |
author2 |
Choueri, Rodrigo Brasil Santos, Gustavo Souza de Araújo, Giuliana Seraphim [UNESP] Cruz, Ana Carolina Feitosa [UNESP] Stremel, Tatiana de Campos, Sandro Xavier Cestari, Marta Margarete Ribeiro, Ciro Alberto Oliveira de Sousa Abessa, Denis Moledo [UNESP] |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal do Paraná (UFPR) Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) Ponta Grossa State University |
dc.contributor.author.fl_str_mv |
Gusso-Choueri, Paloma Kachel [UNESP] Choueri, Rodrigo Brasil Santos, Gustavo Souza de Araújo, Giuliana Seraphim [UNESP] Cruz, Ana Carolina Feitosa [UNESP] Stremel, Tatiana de Campos, Sandro Xavier Cestari, Marta Margarete Ribeiro, Ciro Alberto Oliveira de Sousa Abessa, Denis Moledo [UNESP] |
dc.subject.por.fl_str_mv |
Biomarkers Environmental quality assessment Estuary Genotoxicity Multivariate approach Weight of evidence |
topic |
Biomarkers Environmental quality assessment Estuary Genotoxicity Multivariate approach Weight of evidence |
description |
The goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-03-15 2018-12-11T17:00:27Z 2018-12-11T17:00:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.marpolbul.2016.01.025 Marine Pollution Bulletin, v. 104, n. 1-2, p. 229-239, 2016. 1879-3363 0025-326X http://hdl.handle.net/11449/172462 10.1016/j.marpolbul.2016.01.025 2-s2.0-84955566839 2-s2.0-84955566839.pdf |
url |
http://dx.doi.org/10.1016/j.marpolbul.2016.01.025 http://hdl.handle.net/11449/172462 |
identifier_str_mv |
Marine Pollution Bulletin, v. 104, n. 1-2, p. 229-239, 2016. 1879-3363 0025-326X 10.1016/j.marpolbul.2016.01.025 2-s2.0-84955566839 2-s2.0-84955566839.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Marine Pollution Bulletin |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
229-239 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1797789501111664640 |