Estudo da regeneração de nervos tibiais de ratos Wistar em sutura primária com gap e sem gap, cobertos por segmentos de veia

• Autor(a) principal: Santos, Ewerton Bastos Dos [UNIFESP]
• Data de Publicação: 2012
• Outros Autores: Fernandes, Marcela [UNIFESP], Santos, João Baptista Gomes dos [UNIFESP], Leite, Vilnei Mattioli [UNIFESP], Valente, Sandra Gomes [UNIFESP], Faloppa, Flávio [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S1413-78522012000300006; http://repositorio.unifesp.br/handle/11600/6906
• topic: Fluorescent dyes; Nerve regeneration; Tibial nerve; Wistar rats; Suture techniques; Corantes fluorescentes; Regeneração nervosa; Nervo tibial; Ratos Wistar; Técnicas de sutura

OBJECTIVE: This study compared nerve regeneration in Wistar rats, using epineural neurorrhaphy with a gap of 1.0 mm and without a gap, both wrapped with jugular vein tubes. Motor neurons in the spinal cord between L3 and S1 were used for the count, marked by exposure of the tibial nerve to Fluoro-Gold (FG). METHOD: The tibial nerves on both sides were cut and sutured, with a gap on one side and no gap in the other. The sutures were wrapped with a jugular vein. Four months after surgery the tibial nerves were exposed to Fluoro-Gold and the motor neuron count performed in the spinal cord. RESULTS: The results were statistically analyzed by the paired Wilcoxon test. There was a statistical difference between the groups with and without gap in relation to the motor neuron count (p=0.013). CONCLUSION: The epineural neurorraphy without gap wrapped with jugular vein showed better results for nerve regeneration than the same procedure with gap. Level of Evidence: Experimental Study.