Is there a role for curcumin in the treatment of bipolar disorder?

Detalhes bibliográficos
Autor(a) principal: Brietzke, Elisa [UNIFESP]
Data de Publicação: 2013
Outros Autores: Mansur, Rodrigo Barbachan [UNIFESP], Zugman, André [UNIFESP], Carvalho, André Férrer, Macedo, Danielle Silveira, Cha, Danielle S., Abílio, Vanessa Costhek [UNIFESP], McIntyre, Roger S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1016/j.mehy.2013.02.001
http://repositorio.unifesp.br/handle/11600/36230
Resumo: Curcumin is a polyphenolic nonflavonoid compound extracted from the rhizome of turmeric (Curcuma longa), a plant commonly used in Indian and Chinese traditional medicine to treat rheumatism, cough, inflammation and wounds. Curcumin putative targets, known based on studies of diverse central nervous system disorders other than bipolar disorders (BD) include several proteins currently implicated in the pathophysiology of BD. These targets include, but are not limited to, transcription factors activated by environmental stressors and pro-inflammatory cytoldnes, protein kinases (PICA, PKC), enzymes, growth factors, inflammatory mediators, and anti-apoptotic proteins (Bcl-XL). Herein, we review previous studies on the anti-inflammatory and anti-oxidant properties of curcumin and discuss its therapeutic potential in BD. (C) 2013 Elsevier B.V. All rights reserved.
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spelling Is there a role for curcumin in the treatment of bipolar disorder?Curcumin is a polyphenolic nonflavonoid compound extracted from the rhizome of turmeric (Curcuma longa), a plant commonly used in Indian and Chinese traditional medicine to treat rheumatism, cough, inflammation and wounds. Curcumin putative targets, known based on studies of diverse central nervous system disorders other than bipolar disorders (BD) include several proteins currently implicated in the pathophysiology of BD. These targets include, but are not limited to, transcription factors activated by environmental stressors and pro-inflammatory cytoldnes, protein kinases (PICA, PKC), enzymes, growth factors, inflammatory mediators, and anti-apoptotic proteins (Bcl-XL). Herein, we review previous studies on the anti-inflammatory and anti-oxidant properties of curcumin and discuss its therapeutic potential in BD. (C) 2013 Elsevier B.V. All rights reserved.Universidade Federal de São Paulo, Dept Psychiat, São Paulo, BrazilUniv Fed Ceara, Dept Clin Med, Fortaleza, Ceara, BrazilUniv Fed Ceara, Psychiat Res Grp, Fortaleza, Ceara, BrazilUniv Fed Ceara, Neuropharmacol Lab, Dept Physiol & Pharmacol, Fortaleza, Ceara, BrazilUniversidade Federal de São Paulo, Dept Pharmacol, São Paulo, BrazilUniv Toronto, MDPU, Toronto, ON, CanadaUniversidade Federal de São Paulo, Dept Psychiat, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Pharmacol, São Paulo, BrazilWeb of ScienceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Churchill LivingstoneUniversidade Federal de São Paulo (UNIFESP)Univ Fed CearaUniv TorontoBrietzke, Elisa [UNIFESP]Mansur, Rodrigo Barbachan [UNIFESP]Zugman, André [UNIFESP]Carvalho, André FérrerMacedo, Danielle SilveiraCha, Danielle S.Abílio, Vanessa Costhek [UNIFESP]McIntyre, Roger S.2016-01-24T14:31:36Z2016-01-24T14:31:36Z2013-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion606-612application/pdfhttp://dx.doi.org/10.1016/j.mehy.2013.02.001Medical Hypotheses. Edinburgh: Churchill Livingstone, v. 80, n. 5, p. 606-612, 2013.10.1016/j.mehy.2013.02.001WOS000317995000022.pdf0306-9877http://repositorio.unifesp.br/handle/11600/36230WOS:000317995000022engMedical Hypothesesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-30T20:45:00Zoai:repositorio.unifesp.br/:11600/36230Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-30T20:45Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Is there a role for curcumin in the treatment of bipolar disorder?
title Is there a role for curcumin in the treatment of bipolar disorder?
spellingShingle Is there a role for curcumin in the treatment of bipolar disorder?
Brietzke, Elisa [UNIFESP]
title_short Is there a role for curcumin in the treatment of bipolar disorder?
title_full Is there a role for curcumin in the treatment of bipolar disorder?
title_fullStr Is there a role for curcumin in the treatment of bipolar disorder?
title_full_unstemmed Is there a role for curcumin in the treatment of bipolar disorder?
title_sort Is there a role for curcumin in the treatment of bipolar disorder?
author Brietzke, Elisa [UNIFESP]
author_facet Brietzke, Elisa [UNIFESP]
Mansur, Rodrigo Barbachan [UNIFESP]
Zugman, André [UNIFESP]
Carvalho, André Férrer
Macedo, Danielle Silveira
Cha, Danielle S.
Abílio, Vanessa Costhek [UNIFESP]
McIntyre, Roger S.
author_role author
author2 Mansur, Rodrigo Barbachan [UNIFESP]
Zugman, André [UNIFESP]
Carvalho, André Férrer
Macedo, Danielle Silveira
Cha, Danielle S.
Abílio, Vanessa Costhek [UNIFESP]
McIntyre, Roger S.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Univ Fed Ceara
Univ Toronto
dc.contributor.author.fl_str_mv Brietzke, Elisa [UNIFESP]
Mansur, Rodrigo Barbachan [UNIFESP]
Zugman, André [UNIFESP]
Carvalho, André Férrer
Macedo, Danielle Silveira
Cha, Danielle S.
Abílio, Vanessa Costhek [UNIFESP]
McIntyre, Roger S.
description Curcumin is a polyphenolic nonflavonoid compound extracted from the rhizome of turmeric (Curcuma longa), a plant commonly used in Indian and Chinese traditional medicine to treat rheumatism, cough, inflammation and wounds. Curcumin putative targets, known based on studies of diverse central nervous system disorders other than bipolar disorders (BD) include several proteins currently implicated in the pathophysiology of BD. These targets include, but are not limited to, transcription factors activated by environmental stressors and pro-inflammatory cytoldnes, protein kinases (PICA, PKC), enzymes, growth factors, inflammatory mediators, and anti-apoptotic proteins (Bcl-XL). Herein, we review previous studies on the anti-inflammatory and anti-oxidant properties of curcumin and discuss its therapeutic potential in BD. (C) 2013 Elsevier B.V. All rights reserved.
publishDate 2013
dc.date.none.fl_str_mv 2013-05-01
2016-01-24T14:31:36Z
2016-01-24T14:31:36Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.mehy.2013.02.001
Medical Hypotheses. Edinburgh: Churchill Livingstone, v. 80, n. 5, p. 606-612, 2013.
10.1016/j.mehy.2013.02.001
WOS000317995000022.pdf
0306-9877
http://repositorio.unifesp.br/handle/11600/36230
WOS:000317995000022
url http://dx.doi.org/10.1016/j.mehy.2013.02.001
http://repositorio.unifesp.br/handle/11600/36230
identifier_str_mv Medical Hypotheses. Edinburgh: Churchill Livingstone, v. 80, n. 5, p. 606-612, 2013.
10.1016/j.mehy.2013.02.001
WOS000317995000022.pdf
0306-9877
WOS:000317995000022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Medical Hypotheses
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 606-612
application/pdf
dc.publisher.none.fl_str_mv Churchill Livingstone
publisher.none.fl_str_mv Churchill Livingstone
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268402981666816

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