Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica

Detalhes bibliográficos
Autor(a) principal: Locali, Rafael Fagionato [UNIFESP]
Data de Publicação: 2008
Outros Autores: Matsuoka, Priscila Katsumi [UNIFESP], Gabriel, Edmo Atique [UNIFESP], Bertini Júnior, Ayrton [UNIFESP], La Rotta, Carlos Arnulfo [UNIFESP], Catani, Roberto [UNIFESP], Carvalho, Antonio Carlos [UNIFESP], Buffolo, Enio [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0066-782X2008000500007
http://repositorio.unifesp.br/handle/11600/4370
Resumo: BACKGROUND: The surgical treatment of patency ductus arteriosus is indicated when the clinical intervention fails. However, this treatment may have some complications. OBJECTIVE: To analyze clinical and surgical aspects involved on the treatment of patency ductus arteriosus in premature newborn. METHODS: Twenty two premature newborns, submitted to surgical treatment for patency ductus arteriosus from January, 2000 to June, 2006, were evaluated. There were 77,3% female patients, the mean birth weight was 952,5g and the mean gestational age was 27 weeks. The use of vasoactive drugs, indometacin, echocardiograph parameters and complications, in the pre and postoperative periods were evaluated. RESULTS: In this casuistic 59,1% patients needed intratracheal intubation at birth, 77,3% needed surfactants, 59,1% used vasoactive drugs preoperative. The mean doses of indometacin were 3,43, with dose range 0,1 to 0,25 mg/Kg/day. The mean caliber of arterial duct patent was 1,96 mm. The surgical procedure was carried out through extrapleural approach in 59.1% of the patients, the mean time of postoperative intubation was 30,9 days, and 50% of the patients used vasoactive drugs postoperative. There were 18,1% postoperative complications (postoperative non-fatal complications). CONCLUSION: More than the half of the patients needed intratracheal intubation at birth, surfactant use and vasoactive drugs in the preoperative period. There was greater prevalence of the extrapleural approach during the surgery. In the postoperative period, there was less demand of vasoactive use and there was not deaths related to the surgical procedure.
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spelling Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgicaPatent ductus arteriosus treatment in the premature newborn: clinical and surgical analisysDuctus arteriosus, patentinfant, prematureheart defects, congenitalPersistência do conduto arteriosoprematurocardiopatias congênitasBACKGROUND: The surgical treatment of patency ductus arteriosus is indicated when the clinical intervention fails. However, this treatment may have some complications. OBJECTIVE: To analyze clinical and surgical aspects involved on the treatment of patency ductus arteriosus in premature newborn. METHODS: Twenty two premature newborns, submitted to surgical treatment for patency ductus arteriosus from January, 2000 to June, 2006, were evaluated. There were 77,3% female patients, the mean birth weight was 952,5g and the mean gestational age was 27 weeks. The use of vasoactive drugs, indometacin, echocardiograph parameters and complications, in the pre and postoperative periods were evaluated. RESULTS: In this casuistic 59,1% patients needed intratracheal intubation at birth, 77,3% needed surfactants, 59,1% used vasoactive drugs preoperative. The mean doses of indometacin were 3,43, with dose range 0,1 to 0,25 mg/Kg/day. The mean caliber of arterial duct patent was 1,96 mm. The surgical procedure was carried out through extrapleural approach in 59.1% of the patients, the mean time of postoperative intubation was 30,9 days, and 50% of the patients used vasoactive drugs postoperative. There were 18,1% postoperative complications (postoperative non-fatal complications). CONCLUSION: More than the half of the patients needed intratracheal intubation at birth, surfactant use and vasoactive drugs in the preoperative period. There was greater prevalence of the extrapleural approach during the surgery. In the postoperative period, there was less demand of vasoactive use and there was not deaths related to the surgical procedure.FUNDAMENTO: O tratamento cirúrgico da persistência de canal arterial é indicado quando a intervenção clínica fracassa. No entanto, esse tratamento não é livre de complicações. OBJETIVO: Analisar aspectos clínicos e cirúrgicos envolvidos no tratamento da persistência do canal arterial, em recém-nascidos prematuros. MÉTODOS: No período de janeiro de 2000 a junho de 2006, foram analisados 22 recém-nascidos prematuros submetidos a tratamento cirúrgico para persistência de canal arterial. Do total de pacientes, 77,3% eram do sexo feminino, com peso médio ao nascimento de 952,5 g e idade gestacional média de 27 semanas. O uso de agentes vasoativos, indometacina, parâmetros ecocardiográficos e complicações, nos períodos pré e pós-operatórios, foi avaliado. RESULTADOS: Na casuística avaliada, 59,1% dos pacientes necessitaram de intubação orotraqueal ao nascimento; 77,3%, de surfactante; e 59,1% usaram agentes vasoativos no pré-operatório. O número médio de aplicações de indometacina foi de 3,4, com dosagem variando de 0,1 a 0,25 mg/kg/dia. O calibre médio do canal arterial foi de 1,96 mm. O procedimento cirúrgico foi realizado por abordagem extrapleural em 59,1% dos casos, e no pós-operatório o tempo médio de intubação foi de 30,9 dias, com emprego de agentes vasoativos em 50% dos pacientes. Observaram-se 18,1% de complicações pós-operatórias não-fatais. CONCLUSÃO: Mais da metade dos pacientes necessitou de intubação orotraqueal ao nascimento, emprego de surfactante e agentes vasoativos no período pré-operatório. Houve maior prevalência de abordagem extrapleural durante o ato operatório. No período pós-operatório, houve menor demanda de agentes vasoativos e não houve óbitos diretamente relacionados ao procedimento cirúrgico.Universidade Federal de São Paulo (UNIFESP)UNIFESP, EPM, Sao Paulo, BrazilSciELOSociedade Brasileira de Cardiologia - SBCUniversidade Federal de São Paulo (UNIFESP)Locali, Rafael Fagionato [UNIFESP]Matsuoka, Priscila Katsumi [UNIFESP]Gabriel, Edmo Atique [UNIFESP]Bertini Júnior, Ayrton [UNIFESP]La Rotta, Carlos Arnulfo [UNIFESP]Catani, Roberto [UNIFESP]Carvalho, Antonio Carlos [UNIFESP]Buffolo, Enio [UNIFESP]2015-06-14T13:38:33Z2015-06-14T13:38:33Z2008-05-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion345-349application/pdfapplication/pdfhttp://dx.doi.org/10.1590/S0066-782X2008000500007Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 90, n. 5, p. 345-349, 2008.10.1590/S0066-782X2008000500007S0066-782X2008000500007-en.pdfS0066-782X2008000500007-pt.pdf0066-782XS0066-782X2008000500007http://repositorio.unifesp.br/handle/11600/4370WOS:000256281400007porArquivos Brasileiros de Cardiologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-10-14T11:00:00Zoai:repositorio.unifesp.br/:11600/4370Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-10-14T11:00Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica
Patent ductus arteriosus treatment in the premature newborn: clinical and surgical analisys
title Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica
spellingShingle Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica
Locali, Rafael Fagionato [UNIFESP]
Ductus arteriosus, patent
infant, premature
heart defects, congenital
Persistência do conduto arterioso
prematuro
cardiopatias congênitas
title_short Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica
title_full Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica
title_fullStr Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica
title_full_unstemmed Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica
title_sort Tratamento da persistência de canal arterial em recém-nascidos prematuros: análise clínica e cirúrgica
author Locali, Rafael Fagionato [UNIFESP]
author_facet Locali, Rafael Fagionato [UNIFESP]
Matsuoka, Priscila Katsumi [UNIFESP]
Gabriel, Edmo Atique [UNIFESP]
Bertini Júnior, Ayrton [UNIFESP]
La Rotta, Carlos Arnulfo [UNIFESP]
Catani, Roberto [UNIFESP]
Carvalho, Antonio Carlos [UNIFESP]
Buffolo, Enio [UNIFESP]
author_role author
author2 Matsuoka, Priscila Katsumi [UNIFESP]
Gabriel, Edmo Atique [UNIFESP]
Bertini Júnior, Ayrton [UNIFESP]
La Rotta, Carlos Arnulfo [UNIFESP]
Catani, Roberto [UNIFESP]
Carvalho, Antonio Carlos [UNIFESP]
Buffolo, Enio [UNIFESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Locali, Rafael Fagionato [UNIFESP]
Matsuoka, Priscila Katsumi [UNIFESP]
Gabriel, Edmo Atique [UNIFESP]
Bertini Júnior, Ayrton [UNIFESP]
La Rotta, Carlos Arnulfo [UNIFESP]
Catani, Roberto [UNIFESP]
Carvalho, Antonio Carlos [UNIFESP]
Buffolo, Enio [UNIFESP]
dc.subject.por.fl_str_mv Ductus arteriosus, patent
infant, premature
heart defects, congenital
Persistência do conduto arterioso
prematuro
cardiopatias congênitas
topic Ductus arteriosus, patent
infant, premature
heart defects, congenital
Persistência do conduto arterioso
prematuro
cardiopatias congênitas
description BACKGROUND: The surgical treatment of patency ductus arteriosus is indicated when the clinical intervention fails. However, this treatment may have some complications. OBJECTIVE: To analyze clinical and surgical aspects involved on the treatment of patency ductus arteriosus in premature newborn. METHODS: Twenty two premature newborns, submitted to surgical treatment for patency ductus arteriosus from January, 2000 to June, 2006, were evaluated. There were 77,3% female patients, the mean birth weight was 952,5g and the mean gestational age was 27 weeks. The use of vasoactive drugs, indometacin, echocardiograph parameters and complications, in the pre and postoperative periods were evaluated. RESULTS: In this casuistic 59,1% patients needed intratracheal intubation at birth, 77,3% needed surfactants, 59,1% used vasoactive drugs preoperative. The mean doses of indometacin were 3,43, with dose range 0,1 to 0,25 mg/Kg/day. The mean caliber of arterial duct patent was 1,96 mm. The surgical procedure was carried out through extrapleural approach in 59.1% of the patients, the mean time of postoperative intubation was 30,9 days, and 50% of the patients used vasoactive drugs postoperative. There were 18,1% postoperative complications (postoperative non-fatal complications). CONCLUSION: More than the half of the patients needed intratracheal intubation at birth, surfactant use and vasoactive drugs in the preoperative period. There was greater prevalence of the extrapleural approach during the surgery. In the postoperative period, there was less demand of vasoactive use and there was not deaths related to the surgical procedure.
publishDate 2008
dc.date.none.fl_str_mv 2008-05-01
2015-06-14T13:38:33Z
2015-06-14T13:38:33Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0066-782X2008000500007
Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 90, n. 5, p. 345-349, 2008.
10.1590/S0066-782X2008000500007
S0066-782X2008000500007-en.pdf
S0066-782X2008000500007-pt.pdf
0066-782X
S0066-782X2008000500007
http://repositorio.unifesp.br/handle/11600/4370
WOS:000256281400007
url http://dx.doi.org/10.1590/S0066-782X2008000500007
http://repositorio.unifesp.br/handle/11600/4370
identifier_str_mv Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 90, n. 5, p. 345-349, 2008.
10.1590/S0066-782X2008000500007
S0066-782X2008000500007-en.pdf
S0066-782X2008000500007-pt.pdf
0066-782X
S0066-782X2008000500007
WOS:000256281400007
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Arquivos Brasileiros de Cardiologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 345-349
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia - SBC
publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia - SBC
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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