Análise quantitativa das fibras mielínicas dos nervos laríngeos em humanos de acordo com a idade

• Autor(a) principal: Tiago, Romualdo Suzano Louzeiro [UNIFESP]
• Data de Publicação: 2008
• Outros Autores: Pontes, Paulo Augusto de Lima [UNIFESP], Brasil, Osiris de Oliveira Campones do [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0034-72992008000100008; http://repositorio.unifesp.br/handle/11600/4244
• topic: dysphagia; dysphonia; aging; laryngeal nerves; disfagia; disfonia; envelhecimento; nervos laríngeos

INTRODUCTION AND AIM: To carry out a morphometric analysis of myelinic fibers in laryngeal nerves aiming to identify quantitative changes as a result of aging. Study design: Clinical and experimental. MATERIAL AND METHOD: A 1cm fragment was collected from the superior laryngeal nerves and recurrent laryngeal nerves taken from twelve male cadavers. The sample was divided into two groups: those aged below 60 years (Adult) and those aged 60 years or more (Elderly). The material was evaluated under light microscopy coupled with an image analysis system. RESULTS: The total number of myelinic fibers from the superior laryngeal nerve was similar in both age groups; there was, however, a trend for a higher number of 1μm fibers in the adult group (p=0.0744). The adult group had a higher total number of myelinic fibers in the recurrent laryngeal nerve (p=0.0006), and this difference was seen in fibers with diameters betwee 1-3μm (p<0.007). The adult group had a higher total number of myelinic fibers in the laryngeal nerves (sum of superior laryngeal nerves and recurrent laryngeal nerves fibers) compared to the elderly group (p<0.0091). CONCLUSION:The total number of myelinic fibers in laryngeal nerves is higher for the group aged below 60 years.