Displasia Fibrosa Craniofacial: relato de caso

• Autor(a) principal: Dias, Carlos Antonio Silva
• Data de Publicação: 2017
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UFU
• Texto Completo: https://repositorio.ufu.br/handle/123456789/19269
• topic: Bone diseases; Mutation; Maxillary diseases; Bone diseases; Mutation; Maxillary diseases; CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA

The so-called fibro-osseous lesions of the jows group of lesions that are characterized by the replacement of normal bone by fibrous connective tissue and immature bone. Histopathologically they are similar entities but clinically and radiographically they represent distinct and varied lesions. According to the latest classification of the World Health Organization of 2017, fibro-osseous lesions are divided into Ossifying Fibroma, Fibrous Dysplasia and Cement-Bone Dysplasia. Fibrous Dysplasias specifically result from genetic mutations associated with the GNAS 1 gene, and may depend on the time of occurrence of the genetic modification it can affect a single bone (monostotic) or more than one bone (polyostotic). They are usually asymptomatic and expansive lesions that commonly cause aesthetic and eventually functional imparement. The craniofacial fibrous dysplasia is characterized by the involvement of several contiguous bones of the face concomitantly and, although it affects more than one facial bone, it is considered a monostotic variant. The present work has the objective of approaching the fibrous dysplasia disease and report the clinical case of a patient affected by craniofacial fibrous dysplasia. The clinical and imaging characteristics will be considered, as well as the therapy used.