Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.)
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | LOCUS Repositório Institucional da UFV |
Texto Completo: | http://locus.ufv.br/handle/123456789/2121 |
Resumo: | Concentration and composition of essential oil from 16 different commercial samples of Matricaria chamomilla L. in Brazil were evaluated. The dried samples were acquired from different regions of Brazil and submitted to hydrodistillation in a Clevenger type apparatus for 8 hours. Then the samples were analyzed for their moisture, essential oil and chemical composition in order to verify whether the commercial samples were in agreement with current standards or not. The analysis of moisture content showed the same variance from 9-22% (w/w). Five samples are commercially presented according to National Agency of Sanitary Surveillance (ANVISA), is less than 12%, in the meantime the other three adjacent exceeded this value reaching a content of approximately 20%. The samples content of blue oil ranged from 0.2-0.7% (w/w). Only six samples were in accordance with Brazilian Pharmacopoeia whose oil content is at least 0.4%. The samples were identified and quantified by gas chromatography coupled to mass spectrometry (GC-MS) and gas chromatography (GC) with a flame ionization detector a total of 27 compounds ranging from 46-84% yield. The main constituents were chamazulene (0.8 to 2.9%), β-farnesene (3-13%), the α-bisabolol A oxide (6-48%) and α-bisabolol B oxide (5.2 to 14.9%). It was also found that two other samples exceeded a quantity of α-bisabolol A oxide, and 47.8% to 31%. The sum of the content of α-bisabolol and its oxides in the samples varied from 12 to 61%, highlighting three of them with the highest level of these compounds. In addition to the main compounds, other compounds to a lesser extent also been identified and quantified such as α-muurolol (0.1 to 1.2%), spathulenol (1.3-2.5%), eudesmol β-(0.2-1.5 %), E-espiroéter (2.3 to 7.5%), hexadecanoic acid (7-22%), E,E-α- farnesene (0.1-0.6%) and nonacosane (1.7-3.5%). |
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Oliveira, Betina Pireshttp://lattes.cnpq.br/8227109432707028Maltha, Célia Regina álvareshttp://lattes.cnpq.br/7346715444030145Barbosa, Luiz Claudio de Almeidahttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4781106J2Demuner, Antônio Jacintohttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4783217D3Pinheiro, Antônio Lelishttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4783113E8Bastidas, Alberto de Jesus Oliveros2015-03-26T13:00:26Z2013-09-182015-03-26T13:00:26Z2012-08-10OLIVEIRA, Betina Pires. Analysis of yield and chemical composition of essential oil in commercial samples of chamomile (Matricaria chamomilla L.). 2012. 52 f. Dissertação (Mestrado em Agroquímica analítica; Agroquímica inorgânica e Físico-química; Agroquímica orgânica) - Universidade Federal de Viçosa, Viçosa, 2012.http://locus.ufv.br/handle/123456789/2121Concentration and composition of essential oil from 16 different commercial samples of Matricaria chamomilla L. in Brazil were evaluated. The dried samples were acquired from different regions of Brazil and submitted to hydrodistillation in a Clevenger type apparatus for 8 hours. Then the samples were analyzed for their moisture, essential oil and chemical composition in order to verify whether the commercial samples were in agreement with current standards or not. The analysis of moisture content showed the same variance from 9-22% (w/w). Five samples are commercially presented according to National Agency of Sanitary Surveillance (ANVISA), is less than 12%, in the meantime the other three adjacent exceeded this value reaching a content of approximately 20%. The samples content of blue oil ranged from 0.2-0.7% (w/w). Only six samples were in accordance with Brazilian Pharmacopoeia whose oil content is at least 0.4%. The samples were identified and quantified by gas chromatography coupled to mass spectrometry (GC-MS) and gas chromatography (GC) with a flame ionization detector a total of 27 compounds ranging from 46-84% yield. The main constituents were chamazulene (0.8 to 2.9%), β-farnesene (3-13%), the α-bisabolol A oxide (6-48%) and α-bisabolol B oxide (5.2 to 14.9%). It was also found that two other samples exceeded a quantity of α-bisabolol A oxide, and 47.8% to 31%. The sum of the content of α-bisabolol and its oxides in the samples varied from 12 to 61%, highlighting three of them with the highest level of these compounds. In addition to the main compounds, other compounds to a lesser extent also been identified and quantified such as α-muurolol (0.1 to 1.2%), spathulenol (1.3-2.5%), eudesmol β-(0.2-1.5 %), E-espiroéter (2.3 to 7.5%), hexadecanoic acid (7-22%), E,E-α- farnesene (0.1-0.6%) and nonacosane (1.7-3.5%).No presente trabalho avaliou-se a composição química do óleo essencial de 16 amostras de camomila (Matricaria chamomilla L.) comercializadas no Brasil. As amostras foram adquiridas em regiões distintas do Brasil e submetidas à hidrodestilação em aparelho tipo Clevenger, por 8 horas. Foram analisados teor de umidade, teor de óleo essencial e composição química, objetivando verificar se as amostras estavam de acordo com as normas vigentes de comercialização. Na análise do teor de umidade, verificou-se que o mesmo variou de 9 a 22% (m/m). Cinco amostras comerciais apresentavam-se de acordo com a Agência Nacional de Vigilância Sanitária (ANVISA), ou seja, valor inferior a 12%, três com valores próximos a 12% e as demais superaram esse valor alcançando um teor de até 22%, aproximadamente. Quanto ao teor de óleo essencial houve variação entre 0,2 e 0,7% (m/m). Das amostras analisadas, somente seis amostras estavam de acordo com a Farmacopéia Brasileira cujo teor de óleo recomendado deve ser acima de 0,4% (m/m). Identificou-se e quantificou-se por cromatografia gasosa acoplada a espectrometria de massas (CG-EM) e cromatografia gasosa (CG) com detector por ionização em chama um total de 27 compostos com um rendimento entre 46-84% do total de óleo essencial extraído. Os principais constituintes foram o camazuleno (0,8 2,9%), β-farneseno (3 13%), o óxido de α-bisabolol A (6 48%) e o óxido de α-bisabolol B (5,2-14,9%). Verificou-se ainda que duas amostras superaram as demais em quantidade de óxido de α-bisabolol A, com 47,8% e 31%. O somatório do teor do α-bisabolol e seus óxidos nas amostras variaram de 12 a 61%, destacando três delas com o maior teor desses compostos. Além dos compostos majoritários, outros compostos em menor proporção também foram identificados e quantificados tais como α-muurolol (0,1-1,2%), espatulenol (1,3-2,5%), β-eudesmol (0,2-1,5%), E-espiroéter (2,3-7,5%), ácido hexadecanóico (7-22%), E,E-α-farneseno (0,1-0,6) e nonacosano (1,7-3,5%).Conselho Nacional de Desenvolvimento Científico e Tecnológicoapplication/pdfporUniversidade Federal de ViçosaMestrado em AgroquímicaUFVBRAgroquímica analítica; Agroquímica inorgânica e Físico-química; Agroquímica orgânicaCamomilaÓleos essenciaisComposição químicaBisabololChamomileEssential oilsChemical compositionBisabololCNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA::QUIMICA ORGANICATeor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.)Analysis of yield and chemical composition of essential oil in commercial samples of chamomile (Matricaria chamomilla L.)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:LOCUS Repositório Institucional da UFVinstname:Universidade Federal de Viçosa (UFV)instacron:UFVORIGINALtexto completo.pdfapplication/pdf1877922https://locus.ufv.br//bitstream/123456789/2121/1/texto%20completo.pdf165b3284695cd070005af257d50fbddaMD51TEXTtexto completo.pdf.txttexto completo.pdf.txtExtracted texttext/plain74547https://locus.ufv.br//bitstream/123456789/2121/2/texto%20completo.pdf.txt267cd71f57148f8853822791d864bd2aMD52THUMBNAILtexto completo.pdf.jpgtexto completo.pdf.jpgIM Thumbnailimage/jpeg3568https://locus.ufv.br//bitstream/123456789/2121/3/texto%20completo.pdf.jpg230d93bed5b882c90d0fd555eb0e39ccMD53123456789/21212016-04-07 23:21:20.842oai:locus.ufv.br:123456789/2121Repositório InstitucionalPUBhttps://www.locus.ufv.br/oai/requestfabiojreis@ufv.bropendoar:21452016-04-08T02:21:20LOCUS Repositório Institucional da UFV - Universidade Federal de Viçosa (UFV)false |
dc.title.por.fl_str_mv |
Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.) |
dc.title.alternative.eng.fl_str_mv |
Analysis of yield and chemical composition of essential oil in commercial samples of chamomile (Matricaria chamomilla L.) |
title |
Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.) |
spellingShingle |
Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.) Oliveira, Betina Pires Camomila Óleos essenciais Composição química Bisabolol Chamomile Essential oils Chemical composition Bisabolol CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA::QUIMICA ORGANICA |
title_short |
Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.) |
title_full |
Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.) |
title_fullStr |
Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.) |
title_full_unstemmed |
Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.) |
title_sort |
Teor e composição química do óleo essencial em amostras comerciais de camomila (Matricaria chamomilla L.) |
author |
Oliveira, Betina Pires |
author_facet |
Oliveira, Betina Pires |
author_role |
author |
dc.contributor.authorLattes.por.fl_str_mv |
http://lattes.cnpq.br/8227109432707028 |
dc.contributor.author.fl_str_mv |
Oliveira, Betina Pires |
dc.contributor.advisor-co1.fl_str_mv |
Maltha, Célia Regina álvares |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/7346715444030145 |
dc.contributor.advisor-co2.fl_str_mv |
Barbosa, Luiz Claudio de Almeida |
dc.contributor.advisor-co2Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4781106J2 |
dc.contributor.advisor1.fl_str_mv |
Demuner, Antônio Jacinto |
dc.contributor.advisor1Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4783217D3 |
dc.contributor.referee1.fl_str_mv |
Pinheiro, Antônio Lelis |
dc.contributor.referee1Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4783113E8 |
dc.contributor.referee2.fl_str_mv |
Bastidas, Alberto de Jesus Oliveros |
contributor_str_mv |
Maltha, Célia Regina álvares Barbosa, Luiz Claudio de Almeida Demuner, Antônio Jacinto Pinheiro, Antônio Lelis Bastidas, Alberto de Jesus Oliveros |
dc.subject.por.fl_str_mv |
Camomila Óleos essenciais Composição química Bisabolol |
topic |
Camomila Óleos essenciais Composição química Bisabolol Chamomile Essential oils Chemical composition Bisabolol CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA::QUIMICA ORGANICA |
dc.subject.eng.fl_str_mv |
Chamomile Essential oils Chemical composition Bisabolol |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA::QUIMICA ORGANICA |
description |
Concentration and composition of essential oil from 16 different commercial samples of Matricaria chamomilla L. in Brazil were evaluated. The dried samples were acquired from different regions of Brazil and submitted to hydrodistillation in a Clevenger type apparatus for 8 hours. Then the samples were analyzed for their moisture, essential oil and chemical composition in order to verify whether the commercial samples were in agreement with current standards or not. The analysis of moisture content showed the same variance from 9-22% (w/w). Five samples are commercially presented according to National Agency of Sanitary Surveillance (ANVISA), is less than 12%, in the meantime the other three adjacent exceeded this value reaching a content of approximately 20%. The samples content of blue oil ranged from 0.2-0.7% (w/w). Only six samples were in accordance with Brazilian Pharmacopoeia whose oil content is at least 0.4%. The samples were identified and quantified by gas chromatography coupled to mass spectrometry (GC-MS) and gas chromatography (GC) with a flame ionization detector a total of 27 compounds ranging from 46-84% yield. The main constituents were chamazulene (0.8 to 2.9%), β-farnesene (3-13%), the α-bisabolol A oxide (6-48%) and α-bisabolol B oxide (5.2 to 14.9%). It was also found that two other samples exceeded a quantity of α-bisabolol A oxide, and 47.8% to 31%. The sum of the content of α-bisabolol and its oxides in the samples varied from 12 to 61%, highlighting three of them with the highest level of these compounds. In addition to the main compounds, other compounds to a lesser extent also been identified and quantified such as α-muurolol (0.1 to 1.2%), spathulenol (1.3-2.5%), eudesmol β-(0.2-1.5 %), E-espiroéter (2.3 to 7.5%), hexadecanoic acid (7-22%), E,E-α- farnesene (0.1-0.6%) and nonacosane (1.7-3.5%). |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012-08-10 |
dc.date.available.fl_str_mv |
2013-09-18 2015-03-26T13:00:26Z |
dc.date.accessioned.fl_str_mv |
2015-03-26T13:00:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
OLIVEIRA, Betina Pires. Analysis of yield and chemical composition of essential oil in commercial samples of chamomile (Matricaria chamomilla L.). 2012. 52 f. Dissertação (Mestrado em Agroquímica analítica; Agroquímica inorgânica e Físico-química; Agroquímica orgânica) - Universidade Federal de Viçosa, Viçosa, 2012. |
dc.identifier.uri.fl_str_mv |
http://locus.ufv.br/handle/123456789/2121 |
identifier_str_mv |
OLIVEIRA, Betina Pires. Analysis of yield and chemical composition of essential oil in commercial samples of chamomile (Matricaria chamomilla L.). 2012. 52 f. Dissertação (Mestrado em Agroquímica analítica; Agroquímica inorgânica e Físico-química; Agroquímica orgânica) - Universidade Federal de Viçosa, Viçosa, 2012. |
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http://locus.ufv.br/handle/123456789/2121 |
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Universidade Federal de Viçosa |
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Mestrado em Agroquímica |
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UFV |
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BR |
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Agroquímica analítica; Agroquímica inorgânica e Físico-química; Agroquímica orgânica |
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Universidade Federal de Viçosa |
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